246 Prevalence of depression and anxiety symptoms and clinical characteristics of adult patients with cystic fibrosis: experience with 75 patients from Turkey

Background: Patients with chronic diseases and their caregivers are at risk for mental disorders, such as depression and anxiety. Objectives: This study aimed to investigate the prevalence of depression and anxiety symptoms among cystic fibrosis (CF) patients and their parent caregivers in Iran. Methods: This descriptive-analytical cross-sectional study was carried out on 96 participants, including 60 patients and 36 parents. The Hospital Anxiety and Depression Scale was used to measure the depression and anxiety in this study. The research site was the Pediatric Respiratory Diseases Research Center of the National Research Institute of Tuberculosis and Lung Diseases in Tehran, Iran. SPSS software (version 22) was used to examine and analyze the raw data. Results: The prevalence of anxiety in patients with a mean incidence of 12.17% was higher than that in parents with a mean incidence of 11.81%. Moreover, the prevalence of depression in patients and parents (10.58%) was almost similar. In the patients’ group, there was a direct and significant relationship between the duration of diagnosis with depression and anxiety; nevertheless, there was an inverse and significant relationship between the patient’s age and anxiety. In the parents’ group, there was a significant inverse association between age and depression, as well as between the duration of diagnosis and anxiety. However, there was no significant relationship between anxiety and depression, neither in the parents’ group nor in the patients’ group. Conclusions: The high prevalence of depression and anxiety symptoms among CF patients and their parents indicates the poor mental state of these individuals, which requires planning and implementation of psychological interventions for this group.

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The Prevalence of Depression and Anxiety Symptoms among Overweight/Obese and Non-Overweight/Non-Obese Children/Adolescents in China: A Systematic Review and Meta-Analysis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16030340 ◽

2019 ◽

Vol 16 (3) ◽

pp. 340 ◽

Cited By ~ 10

Author(s):

Simeng Wang ◽

Qi Sun ◽

Lingling Zhai ◽

Yinglong Bai ◽

Wei Wei ◽

...

Keyword(s):

Meta Analysis ◽

Depression Scale ◽

Middle School Student ◽

Chinese Economy ◽

Anxiety Symptoms ◽

Depression Symptoms ◽

Depression And Anxiety ◽

Obese Children ◽

Prevalence Of Depression ◽

Scale Types

With the dramatic growth of the Chinese economy, the number of children/adolescents with being overweight/having obesity is increasing, which has a certain impact on their psychology, such as depression and anxiety symptoms. Our purpose was to conduct a meta-analysis to assess the prevalence and odds ratios of depression and anxiety symptoms among overweight/obese children/adolescents and non-overweight/obese children/adolescents in China. As of July 2018, the three most comprehensive computerized academic databases in China have been systematically screened, namely China national knowledge infrastructure (CNKI) databases, Wanfang databases and Vip databases. The same operations are performed in PubMed and Web of Science (SCIE) databases without language restrictions. Case-control studies on prevalence of depression and anxiety symptoms in overweight/obese children/adolescents in China were analyzed. Study selection and evaluation were performed independently by three authors. Unweighted prevalence, pooled random-effects estimates of odds ratio (OR), and 95% confidence intervals (CI) were all calculated. A total of 11 eligible studies involving 17,894 subjects were included. The prevalence of depression and anxiety symptoms in overweight/obese children/adolescents was significantly higher than that in non-overweight/non-obese children/adolescents (depression: 21.73% vs. 17.96%, OR = 1.46, 95% CI: 1.14, 1.87, p = 0.003; anxiety: 39.80% vs. 13.99%, OR = 1.47, 95% CI: 1.21, 1.79, p < 0.001). Subgroup analyses conducted according to scale types showed that scale types have certain significance to evaluate the relationship between depression symptoms and overweight/obesity. The OR of depression symptoms between overweight/obese children/adolescents and non-overweight/non-obese children/adolescents was greatest on the Middle School Student Mental Health Scale (MSSMHS) was 2.06 (95% CI: 1.41, 3.02, I2 = 0.00%), Center for Epidemiologic Studies Depression Scale (CES-D) was 1.03 (95% CI: 0.84, 1.25, I2 = 0.00%), and Children’s Depression Inventory (CDI) was 1.21 (95% CI: 1.02, 1.42, I2 = 0.00%). We concluded that the prevalence of depression and anxiety symptoms in overweight/obese children/adolescents in China is higher than that in the non-overweight/obese children/adolescents. The results of the study indicate that the prevalence of depression and anxiety symptoms among overweight/obese children/adolescents in Chinese medical institutions should receive more attention. Physical exercise and psychological interventions should be strengthened to prevent psychological problems. However, because of some clear limitations (no clinical interview and few studies), these results should be interpreted with caution.

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Prevalence of Depression and Anxiety Symptoms among Families of Survivors in a Neurosciences Intensive Care Unit (P02.217)

Neurology ◽

10.1212/wnl.78.1_meetingabstracts.p02.217 ◽

2012 ◽

Vol 78 (Meeting Abstracts 1) ◽

pp. P02.217-P02.217

Author(s):

D. Hwang ◽

D. Yagoda ◽

P. Currier ◽

H. Perrey ◽

T. Tehan ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Anxiety Symptoms ◽

Depression And Anxiety ◽

Prevalence Of Depression

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Prevalence of depression and anxiety symptoms in elderly patients admitted in post-acute intermediate care

International Journal of Geriatric Psychiatry ◽

10.1002/gps.2041 ◽

2008 ◽

Vol 23 (11) ◽

pp. 1141-1147 ◽

Cited By ~ 28

Author(s):

A. M. Yohannes ◽

R. C. Baldwin ◽

M. J. Connolly

Keyword(s):

Elderly Patients ◽

Anxiety Symptoms ◽

Intermediate Care ◽

Depression And Anxiety ◽

Prevalence Of Depression

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Prevalence of depression and anxiety in patients with cystic fibrosis and parent caregivers: results of The International Depression Epidemiological Study across nine countries

Thorax ◽

10.1136/thoraxjnl-2014-205983 ◽

2014 ◽

Vol 69 (12) ◽

pp. 1090-1097 ◽

Cited By ~ 167

Author(s):

Alexandra L Quittner ◽

Lutz Goldbeck ◽

Janice Abbott ◽

Alistair Duff ◽

Patrick Lambrecht ◽

...

Keyword(s):

Cystic Fibrosis ◽

Epidemiological Study ◽

Depression And Anxiety ◽

Prevalence Of Depression ◽

Parent Caregivers

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Psychosocial distress in patients with driver-mutant lung cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2021.39.15_suppl.e24125 ◽

2021 ◽

Vol 39 (15_suppl) ◽

pp. e24125-e24125

Author(s):

Lia Head ◽

Nicole Yun ◽

Sanjib Basu ◽

Lauren Rynar ◽

Jill Elizabeth Feldman ◽

...

Keyword(s):

Lung Cancer ◽

Academic Medical Center ◽

Well Being ◽

Psychosocial Distress ◽

Anxiety Symptoms ◽

Depression Symptoms ◽

Rapid Weight Loss ◽

Depression And Anxiety ◽

Prevalence Of Depression ◽

The Impact

e24125 Background: Project PRIORITY, a collaborative research study between The EGFR Resisters and the LUNGevity Foundation, found that 29% of United States respondents had clinical depression. While tyrosine kinase inhibitors (TKI) prolong lives, the impact of an oncogene driven lung cancer diagnosis on emotional well-being is not well studied nor are resource utilization and potential contributing factors to psychosocial distress. Methods: Our primary objective was to study cancer related distress in patients (pts) with newly diagnosed oncogene driver lung cancer. The secondary objective was to correlate distress with neutrophil to lymphocyte ratio (NLR) and body mass index loss (BMI) as a surrogate for cancer cachexia/precachexia to gauge the relationship to psychosocial distress. We retrospectively reviewed pts treated with TKI between 1/1/2008 and 2/1/2021. Sample size was based on estimates of depression in this population. A diagnosis of depression or anxiety was defined by documentation in the visit problem list, and active symptoms were based on progress note documentation. Depression and anxiety were recorded at 6 time points from diagnosis to progression on TKI, and their associations with treatment toxicities, progression free survival (PFS) and overall survival (OS) were assessed. Association with serial BMI and NLR were assessed using longitudinal statistical models. Results: We studied 78 pts: 71.8% female, 62.8% Caucasian, 15.4% African American, 15.6% Hispanic/LatinX, and 11.5% Asian. 94.9% had an EGFR mutation, and 5.1% had an ALK mutation. Prevalence of depression at diagnosis and progression was 11.5% and 25%, with anxiety prevalence 28.2% and 40.6%, respectively. Of these pts, 22.2% had active depression symptoms and 54.5% had active anxiety symptoms at diagnosis, although symptoms were not addressed in 33.3% and 22.7%, respectively. At progression, 68.8% had active depression symptoms and 46.2% had active anxiety symptoms, but symptoms were not addressed in 6.3% and 26.9%, respectively. At diagnosis and progression, 24.4% and 35.9%, respectively, were on treatment for anxiety and/or depression. Social work and psychology evaluated 12.8% and 10.3% of all pts at diagnosis and 10.9% and 17.2% at progression. NLR > 3.5 and > 5 were not associated with depression or anxiety. A more rapid longitudinal decrease in BMI was associated with depression. Grade ≥3 toxicities were not associated with depression or anxiety. Shorter PFS and OS were associated with higher rates of depression, but not anxiety. Conclusions: In this retrospective study of an ethnically diverse patient group at an academic medical center, we found a prevalence of depression and anxiety consistent with the Project PRIORITY findings. We saw an association between depression and more rapid weight loss but did not see correlation with NLR. Prospective evaluation with accurate documentation is needed to better address these questions in future studies.

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High Prevalence of Depression and Anxiety Symptoms among Hospitalized Geriatric Medical Inpatients: A study from a Tertiary Level Hospital in Nepal

University of Toronto Medical Journal ◽

10.5015/utmj.v88i1.1283 ◽

2010 ◽

Vol 88 (1) ◽

Author(s):

Aditya Kumar ◽

Santosh Raj Sharma ◽

Santosh Timalsina ◽

Smith Giri ◽

Vijay Yadav

Keyword(s):

Anxiety Symptoms ◽

Tertiary Level ◽

Depression And Anxiety ◽

High Prevalence ◽

Prevalence Of Depression ◽

Medical Inpatients ◽

Level Hospital

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Assessment on Occurrences of Depression and Anxiety and Associated Risk Factors in the Infertile Chinese Men

American Journal of Men s Health ◽

10.1177/1557988317695901 ◽

2017 ◽

Vol 11 (3) ◽

pp. 767-774 ◽

Cited By ~ 9

Author(s):

Bin Yang ◽

Jianchao Zhang ◽

Yuxia Qi ◽

Pu Wang ◽

Ronghuan Jiang ◽

...

Keyword(s):

Risk Factors ◽

Psychological Symptoms ◽

Short Form ◽

Significant Risk ◽

Anxiety Symptoms ◽

Reproductive Age ◽

Depression And Anxiety ◽

Male Population ◽

Chinese Men ◽

Prevalence Of Depression

The prevalence of depression and anxiety in the Chinese male population with infertility is still uncertain. The prevalence of depression, anxiety, and a combination of both psychological symptoms was 20.8%, 7.8%, and 15.4%, respectively in 771 infertile Chinese men in the current study by the Mental Health Inventory–5 and the State–Trait Anxiety Inventory–Short Form questionnaires. Differences in demographics (age, education, and income) had no noticeable impact on the development of psychological symptoms. Clinical factors such as concomitant disorders (varicocele, epididymal cyst, and erectile dysfunction) were identified as risk factors associated with depressive symptoms ( OR = 1.47; 95% CI [1.14, 1.90]; p < .001) and both depressive and anxiety symptoms ( OR = 1.56; 95% CI [1.17, 2.08]; p < .001). An infertility duration over 2 years was associated with a high risk of anxiety symptoms ( OR = 3.94; 95% CI [1.20, 12.93], p < .02). Other clinical conditions such as type of treatment and quality of sperm were not significant risk factors for psychological symptoms. This study provides evidence that Chinese men of reproductive age who suffer from infertility are vulnerable to psychological distress.

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