LB025-MON QUALITY OF LIFE, COGNITION AND PHYSICAL FUNCTIONING BETWEEN HIGHER AND LOWER INTAKES OF NUTRIENTS OF HOME-DWELLING OLDER AD PATIENTS

CONTEXT: Hemiparesia changes quality of life of patients with stroke making difficult a normal life. OBJECTIVE: To evaluate the effect of Functional Eletric Orthesis (FEO) applied over the paretic leg in the quality of life of stroke patients. METHOD: The quality of life of 50 stroke patients of Associacao de Assistencia a Crianca Deficiente (AACD) was evaluated with SF-36 questionnaire before and after the treatment with a FEO for rehabilitation of walking. We analyzed data according to gender and affected hemisphere. RESULTS: The average values from all domains of SF-36 improved significantly (p<0.001). Female patients improved more than male in Emotional Domain (p=0.04) and presented a trend to be better regarding Bodily Pain and Social Functioning. Patients with right hemiparesia improved more than those with left hemiparesia (p=0.02). CONCLUSION: FEO over a paretic leg is efficient to improve quality of life of stroke patients, mainly Physical Functioning.

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Quality of life during the first 6 months of interferon-b treatment in patients with MS

Multiple Sclerosis Journal ◽

10.1177/135245850000600508 ◽

2000 ◽

Vol 6 (5) ◽

pp. 338-342

Author(s):

J HA Arnoldus ◽

J Killestein ◽

L EMA Pfennings ◽

B Jelles ◽

B MJ Uitdehaag ◽

...

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Side Effects ◽

Physical Functioning ◽

Bodily Pain ◽

Significant Linear Trend ◽

Role Physical ◽

Sf 36 ◽

The Impact

Objectives: To determine the quality of life (QoL) of MS patients during the initial 6 months of treatment with interferon-b (IFN-b). Furthermore, to determine whether changes in QoL relate to disability, emotional state, therapeutic expectations or side effect profile. Background: IFN-b has been shown to have beneficial effects on the course of MS. Since the aim of IFN-b treatment is not to cure but to slow down the disease it is important to know how this treatment affects QoL. Surprisingly, the impact of treatment with IFN-b on QoL measures has not been extensively studied so far. Methods: Case report documentation, including EDSS, SF-36 and MADRAS scores, of 51 relapsing-remitting MS patients treated with IFN-b was obtained at baseline and at months 1, 3 and 6. Patients also filled in a form about their expectations of therapy and a questionnaire on side effects. Results: During treatment there was a significant linear trend indicating improvement in the role-physical functioning (RPF) scale of the SF-36 (F1,50=4.9, P=0.032). A transient decrease at month 1 was found in the scale for bodily pain, indicating more experienced pain (F1,50=19.8, P50.001). Subgroup analysis showed that patients with most depressive symptoms on the MADRAS at baseline contributed most to the increase in RPF scores over time (F1,24=5,6 P=0.026). Furthermore, we found associations between adverse event scores and several domains of QoL. Conclusions: Our findings suggest that IFN-b therapy has an impact on QoL of MS patients in that it improves role-physical functioning and transiently worsens experienced bodily pain. QoL during treatment with IFN-b is influenced by depressive symptoms at baseline as well as by treatment-associated side-effects.

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QUALITY-OF-LIFE STUDY IN PATIENTS WITH METABOLIC SYNDROME AND COGNITIVE DISORDERS

Bulletin Biomedicine and sociology ◽

10.26787/nydha-2618-8783-2021-6-1-13-22 ◽

2021 ◽

pp. 13-22

Author(s):

Zueva I.B. ◽

Yushkova I.D. ◽

Makarenko S.V. ◽

Kim Y.V.

Keyword(s):

Quality Of Life ◽

Metabolic Syndrome ◽

Physical Functioning ◽

Cognitive Functions ◽

Test Score ◽

Neuropsychological Testing ◽

Strong Association ◽

Cognitive Disorders ◽

Aged Patients

Nowadays, there is a tendency for an increasing prevalence of metabolic syndrome (MS) among middle-aged patients. It seems relevant to determine the quality of life in patients with MS and cognitive impairment (CI) in this age group. Aim of the study. Studying the quality of life in patients with MS and CI. Material and methods. In total, 208 people were examined. Out of a total number, 178 patients were divided into 2 groups: some were diagnosed with MS and CI, and some patients had MS but no cognitive deficit. The comparison group consisted of 30 healthy individuals of comparable age. All patients underwent neuropsychological testing. The method of cognitive evoked potential (P300) with the use of EMG/VP Nicolet Viking Select was chosen to quantitatively assess cognitive functions of the patients. Quality of life was assessed by the use of SF 36. Results and discussion. In the group with MS and CI, compared with patients who have MS but no cognitive disorders, the indicators of general health were lower (52.30±13.90 and 58.22±10.96 points, respectively, p<0.05), physical functioning (69.23±19.79 and 77.13±15.46 points, respectively, p<0.05), emotional role functioning (42.17±21.79 and 56.93±19.84 points, respectively, p<0.05), self-assessment of mental state (53.68±11.84 and 58.39±12.4 points, respectively, p<0.05). In patients with MS and cognitive disorders, a strong association was found between the results of the MMSE test (r=0.39; p=0.015), the Wechsler memory test score (r=0.29; p=0.014), the FAB test score (r=0.43; p=0.018), and physical functioning scores. Mental health scores were associated with the results of the Wexler test (r=0.27; p=0.014). In the group with MS and CI, there was a positive correlation between the amplitude of P300 and indicators of physical functioning (r=0.40; p=0.016). Findings. In the group of patients with MS and CI, compared with patients without cognitive disorders, there is a decrease in the quality of life, especially in indicators of physical functioning. The quality-of-life parameters of patients with MS are associated with cognitive functions determined both by neuropsychological testing and by P300.

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Dynamics of quality of life of patients as a method of evaluating surgical treatment outcome in oral and oropharyngeal cancer

Oncologia i radiologia Kazakhstana ◽

10.52532/2663-4864-2021-1-59-31-35 ◽

2021 ◽

Vol 59 (1) ◽

pp. 31-35

Author(s):

N. Trizna ◽

Z. Kaliadich ◽

E. Zhaleika ◽

A. Evmenenko

Keyword(s):

Quality Of Life ◽

Treatment Outcome ◽

Physical Functioning ◽

Oropharyngeal Cancer ◽

Individual Therapy ◽

Quality Of Life Indicators ◽

Eortc Qlq C30 ◽

Oral And Oropharyngeal Cancer ◽

Eortc Qlq

Study of the quality of life indicators is an important part of a comprehensive analysis of new diagnosis, treatment, and prevention methods. It can serve as an additional criterion for selecting individual therapy or rehabilitation, examining the ability to work, and identifying psychological problems. Purpose of the study: The authors took a clinical case to demonstrate the use of внтфьшс monitoring of the quality of life indicators for the assessment of surgical and reconstructive treatment outcome for oral and oropharyngeal cancer. Results: The anticancer treatment effects were reflected in the physical functioning score according to the EORTC QLQ-C30 questionnaire (reduced to 80 points) and some symptomatic scores according to the EORTC QLQ-C30 and EORTC QLQ-H & N35 questionnaires. Medical rehabilitation measures resulted in positive dynamics of physical functioning scores according to the EORTC QLQ-C30 questionnaire (increase to 93.3 points) and symptomatic scores according to the EORTC QLQ-H & N35 questionnaire related to nutrition. At that, the patient has stopped having difficulty eating in public places; his body weight increased. The absence of pain and refusal to take analgesics also testified to successful treatment and improved quality of life. Conclusion: A subjective assessment of the various quality of life aspects in a particular patient provides valuable information about the individual response to the conducted treatment.

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MO068HIGH INTENSITY INTERVAL TRAINING IMPROVES PHYSICAL FUNCTIONING, INFLAMMATION AND QUALITY OF LIFE IN PERITONEAL DIALYSIS PATIENTS

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfw142.05 ◽

2016 ◽

Vol 31 (suppl_1) ◽

pp. i58-i58 ◽

Cited By ~ 1

Author(s):

Myriam Isnard Rouchon ◽

Céline Coutard ◽

Marion Matysiak ◽

Pierre Ravel ◽

Céline Forte ◽

...

Keyword(s):

Quality Of Life ◽

Peritoneal Dialysis ◽

Physical Functioning ◽

Interval Training ◽

Dialysis Patients

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Impact of stimulating cognitive-motor training on neuropsychological status and quality of life in patients with Parkinson's disease

Neurology neuropsychiatry Psychosomatics ◽

10.14412/2074-2711-2018-4-65-71 ◽

2018 ◽

Vol 10 (4) ◽

pp. 65-71

Author(s):

Yu. N. Bykov ◽

T. B. Bender ◽

Yu. N. Vasiliev ◽

A. N. Kalyagin ◽

Т. М. Maksikova ◽

...

Keyword(s):

Quality Of Life ◽

Parkinson’S Disease ◽

Parkinson's Disease ◽

Combination Therapy ◽

Mobile Devices ◽

Physical Functioning ◽

Motor Training ◽

Neuropsychological Status ◽

Sf 36

Motor and non-motor symptoms are identified in the clinical picture of Parkinson's disease (PD). Among its non-motor manifestations, cognitive impairment (CI) and emotional disorders play a special role in PD. It is important to search for new forms and methods of cognitive therapy in patients with PD.Objective:to analyze neuropsychological status and quality of life (QOL) in PD patients and to evaluate the efficiency of personalized combination therapy with a stimulating cognitive motor training on computer and mobile devices in these patients.Patients and methods. The investigation enrolled 112 patients with PD. A study group included 56 PD patients who received a cycle of combination therapy with cognitive-motor training on PC and mobile devices; a control group consisted of 56 PD patients who had only a drug therapy cycle. To evaluate neuropsychological status and QOL, the investigators used the Montreal Cognitive Assessment (MoCA), the McNair and Kahn memory self-evaluation scale, the Hospital Anxiety and Depression Scale (HADS), and the 36-Item Short Form Health Survey (SF-36) questionnaire.Results and discussion. According to MoCA scores, CI of varying severity was diagnosed in the majority of patients: in 75 and 80.4% in the study and control groups, respectively. Depressive syndrome was detected in 53.6 and 64.3% in these groups, respectively. According to the SF-36, the physical status of patients had the greatest effect in reducing their QOL. There were treatment-induced statistically significant positive changes for the following domains: physical functioning (p<0.01), role-physical functioning (p<0.001), pain intensity (p<0.01), general health (p<0.01), role emotional (p<0.0001), and mental health (p<0.01).Conclusion.The investigation has shown the efficiency of personalized therapy including stimulating cognitive-motor training on computer and mobile devices, which improves neuropsychological status and QOL in patients with PD.

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A study of patients’ quality of life more than 5 years after trauma: a prospective follow-up

Health and Quality of Life Outcomes ◽

10.1186/s12955-020-01652-1 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Fanny Vardon-Bounes ◽

Romain Gracia ◽

Timothée Abaziou ◽

Laure Crognier ◽

Thierry Seguin ◽

...

Keyword(s):

Quality Of Life ◽

Economic Impact ◽

Physical Functioning ◽

Major Trauma ◽

Injury Severity ◽

Number Of Patients ◽

Sf 36 ◽

Socio Economic Impact

Abstract Background The long-term fate of severely injured patients in terms of their quality of life is not well known. Our aim was to assess the quality of life of patients who have suffered moderate to severe trauma and to identify primary factors of long-term quality of life impairment. Methods A prospective monocentric study conducted on a number of patients who were victims of moderate to severe injuries during the year 2012. Patients were selected based on an Injury Severity Score (ISS) more than or equal to 9. Quality of life was assessed by the MOS SF-36 and NHP scores as a primary evaluation criterion. The secondary evaluation criteria were the determination of the socio-economic impact on quality of life and the identification of factors associated with disability. Results Two hundred and eight patients were contacted by e-mail or telephone. Fifty-five patients participated in this study (with a participation level of 26.4%), including 78.2% men, with a median age of 46. Significant alterations in quality of life were observed with the NHP and MOS SF-36 scale, including physical and psychological components. This resulted in a major socio-economic impact as 26% of the patients could not resume their professional activities (n = 10), 20% required retraining in other lines of work, and 36.4% had a disability status. The study showed that scores ≤ 85 on the physical functioning variable of the MOS SF 36 scale was associated with disability. Conclusion More than five years after a moderate to severe injury, patients’ quality of life was significantly impacted, resulting in significant socio-economic consequences. Disability secondary to major trauma seems to be associated with a score ≤ 85 on the physical functioning dimension of the MOS SF-36 scale. This study raises the question of whether or not early rehabilitation programs should be implemented in order to limit the long-term impact of major trauma.

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Patient-assessed outcomes after excision of acoustic neuroma: postoperative symptoms and quality of life

Journal of Neurosurgery ◽

10.3171/jns.2001.94.2.0211 ◽

2001 ◽

Vol 94 (2) ◽

pp. 211-216 ◽

Cited By ~ 99

Author(s):

Helen C. Martin ◽

Jagjit Sethi ◽

Dorothy Lang ◽

Glen Neil-Dwyer ◽

Mark E. Lutman ◽

...

Keyword(s):

Quality Of Life ◽

Social Functioning ◽

Acoustic Neuroma ◽

Physical Functioning ◽

Short Form ◽

Content Type ◽

Sf 36 ◽

Postoperative Symptoms ◽

Fine Print

Object. The aim of this study was to assess whether outcomes from excision of acoustic neuroma vary among patients and have a material impact on their quality of life (QOL). Methods. A questionnaire concerning postoperative symptoms and the Short Form 36 (SF-36) QOL instrument were mailed to 97 consecutive patients who had undergone acoustic neuroma surgery via the translabyrinthine approach. The survey response rate was 78% and the symptomatology was consistent with other reports, supporting the representativeness of the sample. The respondents' QOL was rated significantly below published norms and their work capacity was reportedly reduced. Specifically, the following SF-36 dimensions were reduced: physical functioning and role-physical, together with vitality, general health, and social functioning. Greater numbers of postoperative symptoms and larger tumors were associated with a worse rating of physical functioning. More severe balance problems were associated with lower ratings of social functioning. The disparity between the patient's self-estimate and self-measurement and the clinician's assessment of the patient's facial functioning raises doubts about the validity of subjective reports and assessment. Conclusions. The present study supports the use of generic QOL measures to assess outcome and to draw comparisons between different populations.

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