scholarly journals The effect of polyphenol-rich dark chocolate on fasting capillary whole blood glucose, total cholesterol, blood pressure and glucocorticoids in healthy overweight and obese subjects

2009 ◽  
Vol 103 (6) ◽  
pp. 842-850 ◽  
Author(s):  
Suzana Almoosawi ◽  
Lorna Fyfe ◽  
Clement Ho ◽  
Emad Al-Dujaili
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Total Cholesterol ◽  
Whole Blood ◽  
Statistical Significance ◽  
Fasting Blood Glucose ◽  
Dark Chocolate ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Obese Subjects

Numerous studies indicate that polyphenol-rich chocolate reduces fasting blood glucose, blood pressure (BP) and total cholesterol in healthy individuals and hypertensives with or without glucose intolerance. The aim of the present study was to investigate the effect of two doses of polyphenol-rich dark chocolate (DC) on fasting capillary whole blood glucose, total cholesterol and BP and to examine whether improvements in these parameters are associated with changes in adrenocorticoid excretion in overweight and obese individuals. The study used a randomised, single-blind, cross-over design where fourteen overweight and obese subjects were randomised to either take 20 g DC with 500 mg polyphenols then 20 g DC with 1000 mg polyphenols or vice-versa. Participants followed each diet for 2 weeks separated by a 1-week washout period. It was observed that the 500 mg polyphenol dose was equally effective in reducing fasting blood glucose levels, systolic BP (SBP) and diastolic BP (DBP) as the 1000 mg polyphenol dose suggesting that a saturation effect might occur with increasing dose of polyphenols. There was also a trend towards a reduction in urinary free cortisone levels with both groups although it did not reach statistical significance. No changes in anthropometrical measurements were seen. We suggest that more research is required to investigate the mechanism(s) by which polyphenol-rich foods influence health.

scholarly journals Korelasi Lingkar Pinggang dengan Kadar Gula Darah Puasa, Kadar Trigliserida, dan Tekanan Darah pada Mahasiswa Fakultas Kedokteran Universitas HKBP Nommensen

2021 ◽  
Vol 3 (2) ◽  
pp. 08-13
Author(s):  
Ervina Julien Sitanggang
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Young Adults ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Blood Sugar ◽  
Fasting Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Sugar Levels

Introduction: Cardiovascular disease is the number one cause of death globally with an incidence of adolescents and young adults in Indonesia as many as 153.705 cases. Central obesity is associated with the risk of cardiovascular disease due to increase in fasting blood glucose levels, cholesterol and triglyceride levels, and blood pressure. Aims: to determine the correlation between waist circumference and fasting blood glucose levels, triglyceride levels, and blood pressure in young adults. Method: This analytic study with a cross-sectional approach involved 53 young adult subjects (18-25 years old). Waist circumference is measured using a tape measure. Blood sugar and triglyceride levels were measured using Cobas® 6000 analyzer machine from blood samples of subjects after fasting for 8-12 hours. Blood pressure data are obtained by measurement using aneroid sphygmomanometer. Results: In this study, the mean waist circumference of the research subjects was 77,4 cm. No correlation was found between waist circumference and fasting blood sugar levels (p = 0,159). However, a positive correlation was found between waist circumference and triglyceride levels (p = 0,008; r = 0,332), between waist circumference and systolic blood pressure (p = 0,049; r = 0,230), and between waist circumference and diastolic blood pressure (p = 0,017; r = 0,293). Conclusion: waist circumference is positively correlated with triglyceride levels and blood pressure, but does not correlate with fasting blood sugar levels.

scholarly journals Insulin, C-peptide and proinsulin for the biochemical diagnosis of hypoglycaemia related to endogenous hyperinsulinism

2007 ◽  
Vol 157 (1) ◽  
pp. 75-83 ◽  
Author(s):  
D Vezzosi ◽  
A Bennet ◽  
J Fauvel ◽  
P Caron
Keyword(s):  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Diagnostic Specificity ◽  
C Peptide ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Specificity And Sensitivity ◽  
Obese Subjects ◽  
Best Parameters ◽  
Rule Out

Objective: We evaluated the respective value of insulin, C-peptide and proinsulin levels in 33 patients with endogenous hyperinsulinism and in 67 controls to determine the best parameters and thresholds to make or to rule out the diagnosis of endogenous hyperinsulinism. Results: When blood glucose levels were below 2.5 mmol/l, insulin was <21 pmol/l in 8–35% of the patients and in all controls; C-peptide was >0.2 nmol/l in all insulinomas but not in the nesidioblastosis or in the controls; proinsulin was >5 pmol/l in all patients but not in the controls. When fasting blood glucose levels reached 2.5–3.3 mmol/l, proinsulin was <22 pmol/l in all the controls and >22 pmol/l in 74% of the patients. Proinsulin after an overnight fast was below 22 pmol/l in all non-obese controls and above 22 pmol/l in 73% of non-obese patients. Conclusion: Proinsulin levels above 5 pmol/l with blood glucose levels below 2.5 mmol/l during a 72 h fast test represent the best criterion for the diagnosis of endogenous hyperinsulinism, reaching 100% diagnostic specificity and sensitivity. Concomitant C-peptide levels above 0.2 nmol/l also make the diagnosis of all our insulinoma patients, not the diagnosis of nesidioblastosis, while insulin levels have much less diagnostic accuracy. Whether proinsulin levels above 22 pmol/l could also make the diagnosis of endogenous hyperinsulinism in part of the patients at the time of fasting blood glucose levels between 2.5 and 3.3 mmol/l or after an overnight fast in non-obese subjects needs further study.

scholarly journals Fasting blood glucose level and its association with sex, body mass index and blood pressure: a cross sectional study on a Bangladeshi public university students

2017 ◽  
Vol 4 (8) ◽  
pp. 2663
Author(s):  
Md Imam Hossain ◽  
Md. Shariful Islam ◽  
Mirza Rokibul Hasan ◽  
Moriom Akter ◽  
Md. Sadek Hosen Khoka
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Blood Glucose ◽  
University Students ◽  
Blood Glucose Level ◽  
Body Mass ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels

Background: In resource-limited countries like Bangladesh, there is a scarcity of epidemiological researches examining the relationship of blood glucose level with hypertension and BMI among the graduate level students. This research was therefore undertaken to evaluate fasting blood glucose levels of Mawlana Bhashani Science and Technology University students and to check its associations with sex, body mass index (BMI) and hypertension. Methods: For the study the 240 students (120 male and 120 female) were randomly selected. The demographic data of the study subjects were collected by interviewing the subjects with standardized questionnaires. Their fasting blood glucose levels were measured using portable blood glucose meter. The BMI and blood pressure of the subjects were also recorded following standard protocol. Finally the data were analyzed with SPSS software. Results: The fasting blood glucose levels of the study subjects indicated that 0.4% of subjects were diabetic and, 5.4% of subjects were pre-diabetic. The blood glucose levels (mean±SE) of female subjects (4.88±0.07) were higher than that of the male (4.61±0.04) subjects. The mean blood glucose levels of hypertensive subjects (4.81±0.07 mmol/L) were higher than that of the normotensive counterpart (4.73±0.05 mmol/L). The fasting blood glucose levels shows significant positive associations with SBP (r=0.155, p<0.05) and DBP (r=0.149, p<0.05).The fasting blood glucose levels also showed a significant positive association with the BMI (r=0.193, p<0.01) of the subjects. Conclusions: This study reveals the diabetic and hypertension status of the Bangladeshi graduate level students. The result of the study is very important in the context of public concern health of Bangladesh.  

scholarly journals Association between chronic generalized periodontitis and hyperlipidemia – a case control study

2010 ◽  
Vol 9 (2) ◽  
pp. 95-100 ◽  
Author(s):  
Amirisetty Ramesh ◽  
Jacob P Shaju ◽  
RM Zade
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Periodontal Disease ◽  
Total Cholesterol ◽  
Chronic Periodontitis ◽  
Plasma Lipids ◽  
Fasting Blood Glucose ◽  
Low Density ◽  
Glucose Levels ◽  
Blood Glucose Levels

Introduction: Hyperlipidemia is a major risk factor for cardiovascular disease. Periodontal disease is caused by predominantly anaerobic gram negative bacteria. Microbial substances initiate and perpetuate the inflammation resulting in the production of high levels of proinflammatory cytokines and hyperactivity of white blood cells and of blood platelets, thus promoting the development of hyperlipidemia. Objective: To evaluate the plasma lipids (Total cholesterol, Low Density Lipoproteins and Triglycerides) as well as Fasting blood glucose levels in non diabetic, non-obese periodontal disease patients and controls. Materials and methods: 18 subjects with chronic periodontal disease (aged 38 to 50 years) were matched for age, sex and BMI (Body Mass Index) with 18 healthy subjects. Total cholesterol, low density lipoprotein, triglycerides and fasting blood glucose levels were measured using routine enzymatic biochemical methods. Results: Total cholesterol, LDL cholesterol and triglycerides was significantly higher in chronic periodontitis patients by 12% ( p<0.02), 14% ( p<0.03) and 22% ( p<0.03) respectively as compared to controls. Fasting blood glucose levels was higher by 7% (p<0.04) in chronic periodontitis patients than controls. Conclusion: Hyperlipidemia and prediabetic state may be associated with chronic periodontitis. Key words: chronic periodontitis; plasma lipids; body mass index; fasting blood glucose. DOI: 10.3329/bjms.v9i2.5657Bangladesh Journal of Medical Science Vol.09 No.2 Apr 2010 pp.95-100

scholarly journals Effect of laparoscopic sleeve gastrectomy on blood sugar and blood pressure

2019 ◽  
Vol 15 (1) ◽  
pp. 95-102
Author(s):  
Rida J. Al-Basri
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Sleeve Gastrectomy ◽  
Blood Glucose ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Fasting Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels

Background: Surgery is one and may be the most effective method to treat obesity. In the last decade, Laparoscopic Sleeve Gastrectomy is perceived to be less invasive, technically simple, less morbid and more popular form of bariatric surgery. Objectives: This study aims to assess the effect of Laparoscopic Sleeve Gastrectomy on Fasting Blood Glucose Levels and Blood Pressure.  Methods: A prospective controlled study in which 50 obese patients were involved, 36 of patients have hypertension and type 2 diabetes mellitus , 7 patients have type 2 diabetes mellitus only, and 7 patients don’t have hypertension or type 2 diabetes. All patients were submitted to Laparoscopic Sleeve Gastrectomy at Al-Kindy Teaching Hospital between October 2014 and October 2016. Results: Forty five of patients were females, while five were males . Mean age was 34 years, mean height 159 cm mean pre Laparoscopic Sleeve Gastrectomy weight was 121kg. Mean post- Laparoscopic Sleeve Gastrectomy weight was 82kg. Mean weight loss outcome at 1 year follow-up is 32.23% of total body weight. . Preoperative initial mean value of fasting blood glucose was 157.4 mg/dL and the declining occurred at 12 months after Laparoscopic Sleeve Gastrectomy was 97 mg/dL . The hypertension remission rates 1 year after Laparoscopic Sleeve Gastrectomy ranges up to 54% of total number of patients and 75% of those with Hypertension. Conclusions: Laparoscopic Sleeve Gastrectomy has an effect in improving Fasting Blood Glucose Levels and Blood Pressure.

scholarly journals Effect of fasting blood glucose on risk of new‐onset hypertension in rural Chinese population: a 15-year follow-up cohort

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jing Liu ◽  
Nan N. Cheng ◽  
Zi Y. Zhou ◽  
Yue Zhang ◽  
Jie Yang ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Total Cholesterol ◽  
Repeated Measures ◽  
Chinese Women ◽  
Fasting Blood Glucose ◽  
Estimating Equation ◽  
Cut Points ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
New Onset

Abstract Background The purpose of this study was to examine the correlation between fasting blood glucose and new-onset hypertension and examine any synergistically effect modification with multiple risk factors. Methods We conducted post-hoc analyses of repeated-measures data in the original Dongzhi osteoporosis cohort study. In total, 3985 participants without hypertension aged 25–64 years were included in the current analyses. Generalized estimating equation models were used to assess the relationship between fasting blood glucose and risk of new-onset hypertension after adjusting for pertinent covariates and autocorrelations among siblings. Results 393 men (19.4%) and 398 women (20.3%) without hypertension at the baseline developed hypertension by the end of the study period. Compared to lower baseline fasting blood glucose levels (Q1–Q3: < 5.74 mmol/L; clinical cut points: < 5.6 mmol/L), higher baseline fasting blood glucose levels (Q4: ≥ 5.74 mmol/L; clinical cut points: ≥ 5.6 mmol/L and < 7.0 mmol/L) increased the risk of new-onset hypertension significantly [(OR: 1.54, 95% CI 1.19–1.98, P < 0.001); (OR: 1.38, 95% CI 1.09–1.75, P = 0.008)] in women. Additionally, a stronger significant association was found in women with elevated fasting blood glucose on risk of new-onset of hypertension with higher total cholesterol (≥ 5.2 mmol/L) [(OR: 2.76; 95% CI: (1.54, 4.96), P < 0.001)]. However, no association was found between fasting blood glucose and risk of new-onset hypertension in men. Conclusions High fasting blood glucose may be significantly associated with risk of new-onset hypertension in Chinese women, especially in women with higher total cholesterol. Further randomized studies are needed to confirm our findings.

scholarly journals Effects of Aerobic Exercise on Fasting Blood Glucose and Blood Pressure Levels of Diabetic-Hypertensive Clients at a Diabetes Clinicin Accra, Ghana

2021 ◽  
Vol 3 (2) ◽  
pp. 75-84
Author(s):  
Edmund Lotsu ◽  
◽  
Samuel Kwakye ◽  
Tawagidu Mohammed ◽  
Bridgette Opoku ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Aerobic Exercise ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Type 2 Diabetic

Background: Hypertension and diabetes are associated with an increased risk of cardiovascular diseases. Effective interventions are therefore relevant in reducing the morbidity and mortality associated with hypertension and diabetes. We set out to determine the effect of aerobic exercise on type-2 diabetic-hypertensive clients at a diabetes clinic in Accra.Method: Twenty-one participants were recruited from the National Diabetes Management and Research Center in Korle-Bu in Accra.Participants undertook 30 minutes of aerobic exercise comprising, warm up, ergonomic cycling and cool down, three times a week for a period of eight weeks. Fasting blood glucose and blood pressure levels were measured and changes with respect to exercise were analysed. The mixed model ANOVA was used to test for the differences in the weekly blood pressure and blood glucose levels while the paired t-test was used to compare the baseline and final readings of blood pressure and blood glucose levels. Pearson’s correlation test was used to determine the relationship between age and change in blood pressure and blood glucose levels after eight weeks of exercise.Results: Mean systolic blood pressure reduced from 142mmHg to 135mmHg while the mean diastolic blood pressure also reduced from 89mmHg to 84mmHg post exercises. The baseline and eighth week post exercise average blood glucose level were 8.0 mmol/L and 5.2 mmol/L respectively. There were significant differences in baseline and week eight systolic (p = 0.0017), and diastolic (p = 0.006) blood pressure as well as blood glucose (p=0.0027) levels. There was also a significant positive correlation between age and change in blood glucose level (p = 0.036).Conclusion: Aerobic exercise reduces the fasting blood glucose level and blood pressure in type-2 diabetic-hypertensives. Diabetic-hypertensives should therefore be encouraged to participate in aerobic exercises.

scholarly journals Milk Fermented with Lactobacillus casei Strain AP Improves Lipid Profiles in Obese Indonesian Adults

2021 ◽  
Author(s):  
Widodo Widodo ◽  
Anggeria Oktavisa Denta ◽  
Sunarti Sunarti ◽  
Dietmar Haltrich
Keyword(s):  
Blood Glucose ◽  
Total Cholesterol ◽  
Lactobacillus Casei ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Fermented Milk ◽  
Milk Products ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Fermented Milk Products

Obesity and hyperglycemia can trigger various diseases, including diabetes mellitus and cardiovascular ailments. Health-promoting fermented milk products can be useful in tackling these issues. One such product is the fermented milk developed using Lactobacillus casei AP, a probiotic strain from Indonesia that has not been tested in humans thus far. Our objective was to examine the effects of L. casei AP-fermented milk products on lipid profiles, blood glucose levels and monocyte chemoattractant protein-1 (MCP-1) levels in obese adults. A total of 29 obese subjects were given L. casei AP-fermented milk products, and their fasting blood glucose, total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglyceride levels were measured using diagnostic system kits. MCP-1 levels were measured using enzyme-linked immunosorbent assay. It was determined that the administration of L. casei AP-fermented milk products significantly reduced total cholesterol, LDL and triglyceride levels (p &lt; 0.05); however, it did not increase HDL (p &gt; 0.05), MCP-1 or fasting blood glucose levels (p &ge; 0.05). In conclusion, in obese Indonesian adults, L. casei AP-fermented milk might reduce total cholesterol, LDL and triglyceride levels but may not affect HDL, MCP-1 or fasting blood glucose levels.

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