Dietary methyl donor micronutrients intake in relation to psychological disorders in adults

2021 ◽  
pp. 1-33
Author(s):  
Keyhan Lotfi ◽  
Ammar Hassanzadeh Keshteli ◽  
Parvane Saneei ◽  
Hamid Afshar ◽  
Ahmad Esmaillzadeh ◽  
...  
Keyword(s):  
Psychological Distress ◽  
General Health Questionnaire ◽  
Depression Scale ◽  
Psychological Disorders ◽  
Cross Sectional Study ◽  
Dietary Intakes ◽  
Cross Sectional ◽  
Lower Odds ◽  
Methyl Donor ◽  
Stratified Analysis

Abstract Previous investigations have mostly studied an individual methyl donor nutrient in relation to psychological disorders and the findings were inconsistent. We investigated the association of methyl donor micronutrients (folate, B6, B12, choline, betaine, and methionine) with psychological disorders (depression, anxiety, psychological distress) in Iranian adults. In this cross-sectional study, dietary intakes of 3299 adults were collected using a validated food frequency questionnaire. Methyl donor micronutrient score (MDMS) was calculated based on energy-adjusted deciles of each nutrient. Hospital Anxiety and Depression Scale (HADS) and General Health Questionnaire (GHQ), validated for Iranians, have been applied to assess depression, anxiety, and psychological distress. Participants had a mean age of 36.3±7.9 years, of whom 58.5% were women. After considering potential confounders, adults in the top quartile of MDMS, compared to the bottom one, had decreased odds of anxiety (OR: 0.53, 95%CI: 0.37–0.75), depression (OR: 0.75, 95%CI: 0.58–0.97) and psychological distress (OR: 0.61, 95%CI: 0.46–0.80). Stratified analysis revealed that the highest category of MDMS among men was related to a 68% lower odds of anxiety (95%CI: 0.15–0.68). Among women, the top quartile of MDMS was protectively associated with anxiety (OR: 0.60, 95%CI: 0.40–0.90), depression (OR: 0.68, 95%CI: 0.50–0.93) and psychological distress (OR: 0.53, 95%CI: 0.38–0.74). Overweight and obese subjects in the highest quartile of MDMS had a 67%, 35%, and 53% lower odds of anxiety (95%CI: 0.20–0.56), depression (95%CI: 0.44–0.94), and psychological distress (95%CI: 0.31–0.70), respectively. We found that high consumption of methyl donor micronutrients was related to a reduced odds of psychological disorders, especially in women and overweight or obese individuals. Further prospective studies are needed to affirm these findings.

Association between dietary insulin index and load and psychological disorders

2019 ◽  
Vol 123 (2) ◽  
pp. 161-171
Author(s):  
Javad Anjom-Shoae ◽  
Ammar Hassanzadeh Keshteli ◽  
Hamid Afshar ◽  
Ahmad Esmaillzadeh ◽  
Peyman Adibi
Keyword(s):  
Psychological Distress ◽  
General Health Questionnaire ◽  
Depression Scale ◽  
Positive Association ◽  
Psychological Disorders ◽  
Cross Sectional Study ◽  
Dietary Intakes ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
Bottom Quartile

AbstractThe present study was carried out to determine whether the dietary insulin index (DII) and dietary insulin load (DIL) are related to psychological disorders in a cross-sectional study among adults. A total of 3172 Iranian adults (age range of 18–55 years) were included. Data on dietary intakes were collected using a validated dish-based 106-item semi-quantitative FFQ. DII and DIL were calculated using food insulin index values published earlier. To assess depression and anxiety, an Iranian validated version of the Hospital Anxiety and Depression Scale was used. Furthermore, psychological distress was examined using the General Health Questionnaire. Among women, a significant positive association was seen; such that women in the highest quartile of DIL had higher odds of depression than those in the lowest quartile (OR 1·84; 95 % CI 1·14, 2·96). In terms of DII, in the fully adjusted model, women in the top quartile of DII were more likely to be depressed compared with those in the bottom quartile (OR 1·65; 95 % CI 1·05, 2·58). In conclusion, we found a significant positive association between DIL and DII and odds of depression among women, but not in men. However, such findings were not seen for anxiety and psychological distress.

scholarly journals Mother-Father Differences in Postnatal Psychological Distress and Its Determinants in Iran

2017 ◽  
Vol 5 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Hassan Mahmoodi ◽  
Farzaneh Golboni ◽  
Haidar Nadrian ◽  
Moradali Zareipour ◽  
Shayesteh Shirzadi ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Health Care Providers ◽  
General Health Questionnaire ◽  
Mode Of Delivery ◽  
Family Health ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
Three Dimensions ◽  
Care Providers ◽  
Cross Sectional

AIM: The aim of this study was to investigate the mother-father differences in Postnatal Psychological Distress (PPD) and its determinants among the parents with 8-weeks old children.MATERIALS AND METHODS: In this cross-sectional study, applying simple random sampling, 306 postnatal parents with an 8-weeks old infant in Saqqez County, Iran, were invited to answer the General Health Questionnaire-28 (GHQ-28) items through the telephone interview. Fifty-eight subjects declined to participate in the study (Response Rate = 81.04%). The data were analysed using the SPSS Statistics v. 21.RESULTS: About 16.9% of all the parents had PPD. The difference in the prevalence of PPD in three dimensions between the two groups were statistically significant (p < 0.01): social dysfunction (25.8% for fathers vs. 5.6% for mothers), somatic disorders (21% for fathers vs. 7.3% for mothers), and anxiety (21% for fathers vs. 6.5% for mothers). The mode of delivery of the mothers and the level of education, the number of children, monthly income, and being consent with pregnancy among the fathers were significant predictors for PPD.CONCLUSION: The level of PPD was more prevalent among the new fathers compared to the new mothers. Among the fathers, but not the mothers, socioeconomic characteristics were contributed to PPD. Considering the differences in risk factors for maternal and paternal PPD, our findings may help family health care providers and policymakers in designing gender-specific intervention programs and diagnosis tools aimed at PPD prevention among new parents.

Unconfirmed death as a predictor of psychological morbidity in family members of disappeared persons

2018 ◽  
Vol 49 (16) ◽  
pp. 2764-2771
Author(s):  
Amila Isuru ◽  
S. N. Hewage ◽  
Padmakumara Bandumithra ◽  
S. S. Williams
Keyword(s):  
General Health Questionnaire ◽  
Family Members ◽  
Depression Scale ◽  
Civil Conflict ◽  
Cross Sectional Study ◽  
Psychological Morbidity ◽  
Cross Sectional ◽  
Loved One ◽  
2004 Tsunami ◽  
The Disappeared

AbstractBackgroundThe 2004 tsunami, the civil conflict until 2009 and the youth insurrection in the late 1980s in Sri Lanka resulted in many persons being classified as ‘missing’ as they disappeared and were unaccounted for. Our aim was to compare the prevalence of major depressive disorder (MDD) and prolonged grief disorder (PGD) in families of disappeared individuals, who eventually received the mortal remains and those who did not.MethodAn ethically approved cross sectional study was conducted in a purposively selected sample after informed consent. Information on the circumstances of the family member going missing was gathered. Culturally adapted versions of the General Health Questionnaire and the Beck Depression Scale were administered. Those who screened positive were assessed by a psychiatrist on Diagnostic and Statistical Manual of Mental Disorders-5 criteria to arrive at a diagnosis.ResultsOf 391 cases of disappearances studied, MDD (17.5% v. 6%) and PGD (22% v. 7%) were significantly higher in those who did not eventually receive the mortal remains of the disappeared person. Among those who did not receive the mortal remains, being unsure whether the disappeared person was dead or alive was highly predictive of MDD and PGD. Mothers and wives, older family members and those with a family history of mental illness were more vulnerable.ConclusionsFamily members of missing individuals unsure whether their loved one was alive or dead have higher psychological morbidity in the form of MDD and PGD.

scholarly journals Is device-based total and domain-specific sedentary behaviour associated with psychological distress in Flemish workers?

2020 ◽  
Author(s):  
Katrien De Cocker ◽  
Margo Ketels ◽  
Jason A Bennie ◽  
Els Clays
Keyword(s):  
Psychological Distress ◽  
Sedentary Behaviour ◽  
Sedentary Time ◽  
General Health Questionnaire ◽  
Modern Society ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Physically Active ◽  
Work Related ◽  
Domain Specific

Abstract Background There is increasing interest in the association between psychological distress and time spent in sedentary behaviour (e.g. sitting), a highly prevalent behaviour in modern society. The limited evidence is mixed and mainly based on studies using self-reported sedentary time. Few studies have investigated device-based total sedentary time in its association with distress. None, however, have examined device-based domain-specific sedentary time in relation to psychological distress. The aim of this study was to investigate whether device-based total and domain-specific sedentary behaviour were associated with psychological distress. Methods Flemish employees (n = 401; 20–64 years; 42.6% male; 83.6% had a ‘physically active occupation’) of seven organizations in service and production sectors participated. Sedentary behaviour (exposure) was assessed by two Axivity AX3 accelerometers (one placed on the thigh and one placed between the shoulders) for two to four consecutive working days. Based on diary completion, domain-specific sedentary behaviour (leisure vs. work) was assessed. The 12-item General Health Questionnaire was used to assess psychological distress (outcome). Adjusted hierarchical multiple regression models were conducted to report on the associations between total and domain-specific sedentary behaviour and psychological distress. Results About 35% of the sample had high levels of distress and average total sedentary time was 7.2 h/day. Device-based total sedentary behaviour [B = −0.009, 95% confidence interval (CI), −0.087 to 0.068], leisure-time (B = 0.001, 95% CI, −0.017 to 0.018) and work-related (B = 0.004, 95% CI, −0.006 to 0.015) sedentary behaviour were not significantly associated with psychological distress. Conclusion This cross-sectional study examining the association between device-based total and domain-specific sedentary behaviour and psychological distress among employees showed a lack of significant findings.

scholarly journals Does pain, psychological distress and deteriorated family economy follow traumatic amputation among war casualties? A retrospective, cross-sectional study from Gaza

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e029892 ◽  
Author(s):  
Hanne Edoy Heszlein-Lossius ◽  
Yahya Al-Borno ◽  
Samar Shaqqoura ◽  
Nashwa Skaik ◽  
Lasse Melvaer Giil ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Family Income ◽  
General Health Questionnaire ◽  
Cross Sectional Study ◽  
Physical Pain ◽  
Rehabilitation Centre ◽  
Cross Sectional ◽  
Family Economy ◽  
Current Employment Status ◽  
Extremity Amputation

ObjectivesThe aim of this study was to explore determinants of psychosocial distress and pain in patients who have survived severe extremity amputation in Gaza.SettingThis study was conducted in a secondary care rehabilitation centre in Gaza, Palestine. The clinic is Gaza’s sole provider of artificial limbs.ParticipantsWe included 254 civilian Palestinians who had survived but lost one or more limb(s) during military incursions from 2006 to 2016. We included patients with surgically treated amputation injuries who attended physical rehabilitation at a specialist prosthesis centre in Gaza. Amputees with injuries prior to 2006 or non-military related injuries were excluded.We assessed their pain and psychological stress using the General Health Questionnaire (GHQ-12). We used income, amputation severity scored by proximity to torso, current employment status, loss of family members and loss of home as independent variables.ResultsThe amputees median age was 23 years at the time of trauma, while a median of 4.3 years had passed from trauma to study inclusion. Nine of 10 were male, while 43 were children when they were amputated (17%≤18 years). One hundred and ninety-one (75%) were unemployed and 112 (44%) reported unemployment caused by being amputated. Pain was the most frequent problem, and 80 amputees (32%) reported to suffer from daily pain. Family income was significantly correlated with the physical pain (OR=0.54, CI 0.36 to 0.80, p=0.002). Psychological distress was higher among unemployed amputees (OR=1.36, CI 1.07 to 1.72, p=0.011). We found no association between psychological distress (GHQ-scores) and the extent of the initial amputation.ConclusionPain and psychological distress following war-related extremity amputation of one or more limbs correlated stronger with deteriorated family economy and being unemployed than with the anatomical and medical severity of extremity amputations.

Relationship between perceptions of treatment goals and psychological distress in patients with advanced cancer.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 11621-11621
Author(s):  
Amanda L. Jankowski ◽  
Deborah Anne Forst ◽  
Joseph Greer ◽  
Ryan David Nipp ◽  
Lauren Waldman ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Cognitive Dissonance ◽  
Advanced Cancer ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Treatment Goal ◽  
Depression Symptoms ◽  
Cross Sectional ◽  
Patients At Risk ◽  
The Relationship

11621 Background: Several studies have demonstrated discordance between how patients perceive their goal of treatment versus how they perceive their oncologist’s goal. Studies evaluating the extent and risk factors of this discordance are lacking. Methods: We conducted a cross-sectional study of 559 patients with incurable lung, gastrointestinal, breast, and brain cancers. We used the Perception of Treatment and Prognosis Questionnaire to assess patients’ perceptions of both their treatment goal and their oncologist’s goal and categorized responses: 1) patients who reported that both their goal and their oncologist’s goal was concordant (either to cure or not to cure); and 2) patients who reported discordant perceptions of their goal versus their oncologist’s goal. We assessed patients’ psychological distress using the Hospital-Anxiety-and-Depression-Scale and used linear regression to assess the relationship between patients’ perceptions of their treatment goal and psychological outcomes. Results: 61.7% of patients reported that both their goal and their oncologist’s goal was non-curative; 19.3% reported that both their goal and their oncologist’s goal was to cure their cancer; and 19.0% reported discordance between their goal and their perception of the oncologist’s goal. Older age (OR = 0.98, P = 0.01), non-Hispanic ethnicity (OR = 0.31, P = 0.049), and higher education (OR = 0.62, P = 0.042) were associated with lower likelihood of reporting discordant goals. Patients with discordant perceptions of their goal and their oncologist’s goal reported higher anxiety (B = 1.56, P = 0.003) compared to those who reported that both their goal and their oncologist’s goal was curative. Patients who reported both their goal and the oncologist’s goal was non-curative had higher depression symptoms (B = 1.06, P = 0.013) compared to those who reported that both their goal and the oncologists’ goal was curative. Conclusions: One-fifth of patients with advanced cancer report discrepancies between their perceptions of their own and their oncologists’ treatment goal which is associated with psychological distress. Tools are needed to identify patients at risk of cognitive dissonance about their prognosis.

scholarly journals Prevalence and Associated Factors of Psychological Distress and Burnout among Medical Students: Findings from Two Campuses

2021 ◽  
Vol 18 (16) ◽  
pp. 8446
Author(s):  
Nik Muhammad Arif Nik Ahmad ◽  
Nurhanis Syazni Roslan ◽  
Shaiful Bahari Ismail ◽  
Ramyashilpa D. Nayak ◽  
Muhamad Ridzuan Jamian ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Medical Students ◽  
Medical Training ◽  
General Health Questionnaire ◽  
Skills Training ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Work Related ◽  
Brief Cope ◽  
And Coping

Medical training is intensive and predisposes students to psychological distress and burnout. Unaddressed burnout in medical training may persist in the internship phase and impact the quality of patient care. While some associations have been established, the link between some individual factors and training characteristics with distress and burnout in medical training remained unclear. In this study, we aim to examine the prevalence of psychological distress and burnout, and its association with gender, training phase, funding status, cumulative grade points average (CGPA), and coping strategies among medical students. The study applied a multicenter cross-sectional study design and convenience sampling on medical students from two medical schools from Malaysia and India. We used a self-reporting instrument that includes demographic details, the 12-item General Health Questionnaire (GHQ), the Copenhagen Burnout Inventory (CBI), and the Brief Coping Orientation to Problems Experienced (Brief COPE). A total of 748 medical students participated in the study. The prevalence of psychological distress, personal-related, work-related, and patient-related burnout were 33.0%, 56.1%, 35.0%, and 26.2%, respectively. Being male, clinical year, self-funded, and having a CGPA of more than 3.50 predicted psychological distress and burnout with mixed results. Maladaptive coping mechanisms consistently predicted the risk of psychological distress and burnout by more than two times. The findings indicate that primary and secondary mental health interventions have a role in medical training. A systematic intervention should incorporate coping skills training alongside institutional-targeted intervention.

scholarly journals Adherence to low carbohydrate diet and prevalence of psychological disorders in adults

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Soraiya Ebrahimpour-Koujan ◽  
Ammar Hassanzadeh Keshteli ◽  
Hamid Afshar ◽  
Ahmad Esmaillzadeh ◽  
Peyman Adibi
Keyword(s):  
Psychological Distress ◽  
Depression Scale ◽  
Psychological Disorders ◽  
Carbohydrate Intake ◽  
Carbohydrate Diet ◽  
Cross Sectional ◽  
Low Carbohydrate Diet ◽  
Increased Risk ◽  
Low Carbohydrate ◽  
Prevalence Of Depression

Abstract Background Although individual macronutrients were studied in relation to mental health, no information exist about the association between adherence to low carbohydrate diet and psychological disorders. This study was conducted to investigate the association between adherence to a low carbohydrate diet and prevalence of psychological disorders among Iranian adults. Methods In this cross-sectional study on 3362 adult men and women, dietary intakes were examined by the use of a validated semi-quantitative food frequency questionnaire. Low carbohydrate diet (LCD) score was computed for each participant based on deciles of percentages of energy from macronutrients. Then the scores of carbohydrate, protein and fat intake for each participant were summed up to achieve the overall LCD score, which ranged from 3 (highest carbohydrate intake and lowest fat and protein intakes) to 30 (lowest carbohydrate intake and highest fat and protein intakes). Anxiety, depression, and psychological distress were assessed by validated Iranian versions of the Hospital Anxiety and Depression Scale and General Health Questionnaire-12. Results Prevalence of depression, anxiety and psychological distress in the whole population were 28.0, 13.3 and 22.6%, respectively. No significant differences were observed in the distribution of depression, anxiety and psychological distress across different quartiles of LCD score. After controlling for potential confounders, no significant association was seen between LCD score and prevalence of depression (OR for the highest vs. the lowest quartile of LCD score: (1.15; 95% CI: 0.93, 1.39). Consumption of LCD was not also associated with increased risk of anxiety (0.82; 95% CI: 0.59, 1.14) and psychological distress (0.92; 95% CI: 0.72, 1.16). These associations did not alter when the analyses were done stratified by gender or BMI status. Conclusion Adherence to the low carbohydrate diet, which contains high amount of fat and proteins but low amounts of carbohydrates, was not associated with increased odds of psychological disorders including depression, anxiety and psychological distress. Given the cross-sectional nature of the study which cannot reflect causal relationships, longitudinal studies, focusing on types of macronutrients, are required to clarify this association.

Comparison of the psychological health of students at the higher institutes of nursing and health techniques: A Moroccan multicentre study

2021 ◽  
pp. 002076402110621
Author(s):  
Ali Ikrou ◽  
Sam Gnanapragasam ◽  
Redouane Abouqal ◽  
Jihane Belayachi
Keyword(s):  
Psychological Distress ◽  
Academic Success ◽  
Nursing Students ◽  
Psychological Health ◽  
General Health Questionnaire ◽  
Female Gender ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Convenience Sample

Background: Mental health is essential to students’ academic success as well as their ability to participate fully and meaningfully throughout all aspects of their lives and throughout their lifespan. Aims: This study aims to determine the psychological health status of Moroccan nursing and technique health students. In doing so, it also seeks to compare differences based on sociodemographic factors. Method: A multicenter cross-sectional study with a convenience sample was conducted with 2,054 participants in the academic year of 2018/2019. A set of socio-demographic information were collected, and The General Health Questionnaire-12 (GHQ-12) was used. Results: The mean GHQ-12 score was 4.33 ± 2.61, and 58.7% respondents scored 4 and above in the GHQ-12 scores and thus were considered to be in psychological distress. Students’ psychological distress was associated with female gender (60.4% for female compared to 52.4% for men, p = .003); living in parental residence (61.6% compared to 54.7% living away parental residence; p = .02 ), the second and the third training level year respectively (64.6%; 59.2%) compared to first-year (55.2%, p = .001), and midwifery and nursing students (61.6%; 60.3%) as compared to technique health students (43.6%, p = .001). Conclusions: It appears that a substantial number of students have psychological distress and this is likely to have negative effects on students’ educational attainment and wider wellbeing.

Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study

2020 ◽  
pp. 1-11
Author(s):  
Hadis Mozaffari ◽  
Manije Darooghegi Mofrad ◽  
Pamela J Surkan ◽  
Mohammadreza Askari ◽  
Leila Azadbakht
Keyword(s):  
Psychological Distress ◽  
Dietary Intake ◽  
Psychological Disorders ◽  
Cross Sectional Study ◽  
B Vitamins ◽  
Dietary Vitamin ◽  
Vitamin B ◽  
Sectional Study ◽  
Iranian Women ◽  
Cross Sectional

Abstract Objective: B-vitamins affect brain function through multiple pathways. Given limited evidence on the relationship between dietary intake of these vitamins and psychological disorders, we examined dietary intake of vitamin B6-9-12 in relation to psychological disorders among Iranian women. Design: Cross-sectional study. Dietary intake was assessed using a valid and reliable FFQ. To assess psychological disorders, we used a version of the Depression Anxiety Stress Scale-21 validated in Iran. Setting: Ten public health centres in southern Tehran, Iran. Participants: A total of 447 female participants aged 20–50 years. Results: The median values of vitamin B6 (pyridoxine), B9 (folate) and B12 (cobalamin) were 1·30 mg/d, 313·89 µg/d and 3·99 µg/d, respectively. After adjustment for potential confounders, dietary vitamin B6 intake was associated with lower odds of depression (OR: 0·54; 95 % CI: 0·31, 0·95; Ptrend: 0·03). However, there was a positive association between dietary vitamin B12 intake with the odds of depression (OR: 2·05; 95 % CI: 1·17, 3·60; Ptrend: 0·01) and psychological distress (OR: 2·00; 95 % CI: 1·17, 3·41; Ptrend: 0·01). No association was found between vitamin B9 with any psychological disorders. Conclusions: Women with higher dietary intakes of vitamin B6 had lower likelihood of depression. However, women with higher dietary intake of vitamin B12 had higher odds of depression and psychological distress. Future prospective studies in different populations are needed to clarify whether B-vitamin deficiency is a cause or consequence of psychological disorders.

Sign in / Sign up

Export Citation Format

Share Document