Reproduction in the buffalo-cow: pH of the vaginal secretions

1958 ◽  
Vol 51 (1) ◽  
pp. 70-71
Author(s):  
M. R. Shalash
Keyword(s):  
Ph Value ◽  
Vaginal Secretion ◽  
Vaginal Secretions ◽  
Buffalo Cow ◽  
Sex Cycle

1. Fifty buffalo-cows were used for studying the pH of the vaginal secretion at different stages of the sex cycle.2. Highly significant differences were found in the pH value of the vaginal secretions during the different stages of the sex cycle. The average was 7·3 during oestrus, 8·1 during dioestrus and 8·3 during pregnancy.

Odour recognition by male hamsters: discrimination of the hormonal state of females by odour from vaginal secretions

1985 ◽  
Vol 105 (2) ◽  
pp. 255-262 ◽  
Author(s):  
E. Steel
Keyword(s):  
Scent Marking ◽  
Oestrous Cycle ◽  
Vaginal Secretion ◽  
Vaginal Secretions ◽  
Marking Behaviour ◽  
Circulating Levels

ABSTRACT Male hamsters were tested for their interest in females on different days of the oestrous cycle. Behaviour of males towards novel females was measured and (after exposure to vaginal secretion) towards females that matched or did not match that vaginal odour. Because pro-oestrous (day 4) females lay trails of vaginal secretion and will become receptive within a few hours, it was predicted that males would show more interest in day 4 than in other dioestrous females. While males showed no preference for novel, pro-oestrous females over dioestrous females, after pre-exposure to odour, their response to females was determined by the cycle day of the vaginal secretion to which they had been exposed. Males pre-exposed to vaginal odour from females carrying large implants of oestrogen preferred to spend more time with females who matched that vaginal odour than mismatching females and to sniff them more. This preference was not seen if the females carried small oestrogen implants or had no replacement oestrogen. This suggests that pro-oestrous females (who are known to have high circulating levels of oestrogen) can, by means of their scent-marking behaviour, attract and keep males nearby until they become receptive. J. Endocr. (1985) 105, 255–262

scholarly journals Immunoglobulin G, Plasma Cells, and Lymphocytes in the Murine Vagina after Vaginal or Parenteral Immunization with Attenuated Herpes Simplex Virus Type 2

1998 ◽  
Vol 72 (6) ◽  
pp. 5137-5145 ◽  
Author(s):  
Earl L. Parr ◽  
Margaret B. Parr
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
B Lymphocytes ◽  
Plasma Cells ◽  
Vaginal Secretion ◽  
Serum Titer ◽  
Vaginal Secretions ◽  
Parenteral Immunization ◽  
Simplex Virus

ABSTRACT This investigation evaluated immunity to vaginal herpes simplex virus type 2 (HSV-2) infection after local or parenteral immunization with attenuated HSV-2. Vaginal immunization induced sterilizing immunity against challenge with a high dose of wild-type virus, whereas parenteral immunizations protected against neurologic disease but did not entirely prevent infection of the vagina. Vaginal immunization caused 86- and 31-fold increases in the numbers of immunoglobulin G (IgG) plasma cells in the vagina at 6 weeks and 10 months after immunization, whereas parenteral immunizations did not increase plasma cell numbers in the vagina. Vaginal secretion/serum titer ratios and specific antibody activities in vaginal secretions and serum indicated that IgG viral antibody was produced in the vagina and released into vaginal secretions at 6 weeks and 10 months after vaginal immunization but not after parenteral immunizations. In contrast to the case for plasma cells, the numbers of T and B lymphocytes in the vagina were similar in vaginally and parenterally immunized mice. Also, lymphocyte numbers in the vagina were markedly but similarly increased by vaginal challenge with HSV-2 in both vaginally and parenterally immunized mice. Lymphocyte recruitment to the vagina after virus challenge appeared to involve memory lymphocytes, because it was not observed in nonimmunized mice. Thus, local vaginal immunization with attenuated HSV-2 increased the number of IgG plasma cells in the vagina and increased vaginal secretion/serum titer ratios to 3.0- to 4.7-fold higher than in parenterally immunized groups but caused little if any selective homing of T and B lymphocytes to the vagina.

La malattia infiammatoria pelvica

2020 ◽  
Vol 23 (8) ◽  
pp. 207-211
Author(s):  
Sara Tagliani ◽  
Silvia Ventresca ◽  
Lorenzo Mambelli ◽  
Alessandro Cuppari ◽  
Stefano Missiroli ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Chlamydia Trachomatis ◽  
Laboratory Data ◽  
Microscopic Analysis ◽  
Vaginal Swab ◽  
Sexually Active ◽  
Vaginal Secretion ◽  
Vaginal Secretions ◽  
Reproductive Life ◽  
Clinical Conditions

The paper describes a case of Pelvic Inflammatory Disease (PID) in a fourteen-year-old girl who presented with salpingitis, low abdominal pain, fever, high inflammation indexes and infection by Chlamydia trachomatis and Gardnerella. As guidelines suggest, she was treated with doxycycline, metronidazole and ceftriaxone and her clinical conditions rapidly improved. PID can develop also in teenagers, especially if sexually active, and it must be differentiated from other causes of acute abdomen. The diagnosis can be based on the presence of pain and on at least one criterion between clinical objectivity (fever, vaginal secretions) and laboratory data (vaginal swab, blood exams, vaginal secretion microscopic analysis). Instrumental exams can support the diagnosis but sometimes only laparoscopy and biopsy can reveal a condition of PID. Adequate antibiotic treatment should be performed to avoid complications over future reproductive life.

scholarly journals The state of some protective factors of the vaginal mucosa in healthy cows and cows with mycoplasmosis

2021 ◽  
Vol 36 ◽  
pp. 06008
Author(s):  
Roman Vasiliev ◽  
Sergey Kovalev ◽  
Vyacheslav Trushkin ◽  
Alexey Prusakov ◽  
Vladimir Ponamarev
Keyword(s):  
Protective Factors ◽  
Mucous Membrane ◽  
Defense Mechanisms ◽  
Specific Treatment ◽  
The State ◽  
Vaginal Mucosa ◽  
Hydrogen Ions ◽  
Vaginal Secretion ◽  
Protective Properties ◽  
Vaginal Secretions

Genital mycoplasmosis in cows is a disease accompanied by a latent course, which complicates its timely diagnosis and the appointment of specific treatment. This disease may lead to infertility. An obstacle to the introduction of pathogens into the epithelium of the mucous membrane is a variety of defense mechanisms. A study of the state of the protective properties of the vaginal mucosa in healthy and mycoplasma-infected cows was carried out by determining the concentration of hydrogen ions and immunoglobulins in vaginal secretions. The results of the study showed a shift in the reaction of vaginal secretions towards neutrality in mycoplasmosis. Thus, the persistence of mycoplasmas in the mucous membrane of the vagina of cows causes a change in the protective properties of the vaginal secretion, as a result of which conditions are created that promote the activation of pathogenic microflora.

scholarly journals Döderlein. Die Scheidensecretuntersuchungen. (Centralblatt für gynäkologie, No. I, 1894). Examination of vaginal secretions

2020 ◽  
Vol 8 (4) ◽  
pp. 387-388
Author(s):  
V. Stroganov
Keyword(s):  
Puerperal Fever ◽  
Vaginal Secretion ◽  
Vaginal Secretions ◽  
In The Beginning

In the beginning, D. is reviewing the results of studies by Burguburu, Williams, and Burckhardt. These results are quite similar to those presented by the author in his monograph Vaginal secretion and its significance in the development of puerperal fever. Then D. proceeds to the analysis of the above article by Krnig. The last day about the constant acidity of the vaginal secretion (which does not agree with the research of Dderlin and others) he explains by the property of the applied sensitive reactive papers, as well as by the amphoteric reaction.

Biostatistics Health Assessment of Matrix Metalloproteinases in Vaginal Secretions in Late Pregnant Women

2021 ◽  
Vol 11 (7) ◽  
pp. 2006-2010
Author(s):  
Chuanming Sun ◽  
Rongsheng Zhou ◽  
Lihua Yang
Keyword(s):  
Matrix Metalloproteinases ◽  
Pregnant Women ◽  
Health Assessment ◽  
Effective Intervention ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Vaginal Infection ◽  
Vaginal Secretion ◽  
Vaginal Secretions ◽  
Experimental Group

Objective: The health management of pregnant women in late pregnancy is difficult. Once vaginal infection occurs, adverse pregnancy outcomes will occur. The aim of this study was to explore the application value of biostatistics health assessment of matrix metalloproteinases (MMP) in vaginal secretions in late pregnant women with vaginal infection. Methods: A total of 120 late pregnant women with vaginal infection, including vulvovaginal candidiasis (WC) in 70 cases and bacterial vaginosis (BV) in 50 cases, were selected as the experimental group. Another 80 pregnant women with normal vaginal secretion in the same gestational week were randomly selected as the control group. Vaginal soft capsule of mycomycin was used in the treatment. The expression levels of MMP-8 and MMP-9 in vaginal secretions before and after treatment were detected by enzyme-linked immunosorbent assay (ELISA) and smear immunohistochemistry, Results: Both the ELISA and immunohistochemistry analysis showed that the levels of MMP-8 and MMP-9 in the vaginal secretion of experimental group were significantly increased than the data of control group (P < 0.05). After effective intervention, the levels of MMP-8 and MMP-9 were significantly lower than those before treatment (P < 0.05). Conclusion: The late pregnant women with vaginal infection was accompanied by the high level of MMP-8 and MMP-9 in vaginal secretions. Effective intervention will lead the reduction of MMP. Thus, the biostatistics health assessment of MMP is important for the late pregnant women with vaginal infection.

scholarly journals Vulvovaginal Candidiasis in Pregnant Women and its Importance for Candida Colonization of Newborns

Folia Medica ◽  
2016 ◽  
Vol 58 (2) ◽  
pp. 108-114 ◽  
Author(s):  
Liliya G. Zisova ◽  
Anastasia A. Chokoeva ◽  
Georgi I. Amaliev ◽  
Penka V. Petleshkova ◽  
Tsonka М. Miteva-Katrandzhieva ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Vulvovaginal Candidiasis ◽  
Vaginal Candidiasis ◽  
Candida Colonization ◽  
Vaginal Secretion ◽  
Candida Spp ◽  
Sabouraud Agar ◽  
Predominant Species ◽  
Vaginal Secretions ◽  
Yeast Assay

AbstractVulvovaginal candidiasis is the second most common cause of vaginitis worldwide (after bacterial candidiasis). Maternal vulvovaginal candidiasis is a major risk factor for Candida colonization and infection of the infant where prognosis depends on different predisposing factors. The aim of this study was to determine the incidence and the etiological structure of vulvovaginal candidiasis in pregnant women and its impact on Candida colonization of newborns.Materials and methods: Samples of vaginal secretions from 80 healthy pregnant women who were clinically suspicious for Candida vaginitis were collected within 48 hours before delivery. Samples for probable Candida colonization from the oral mucosa and feces were collected from their newborns within 47-72 hours after birth. Samples were plated on Sabouraud agar, followed by species identification by API Candida yeast assay.Results: Twenty-three (28.75 ± 5.06%) of the evaluated pregnant women were positive for Candida spp. Positive samples for Candida colonization were found in 18 (22.22 ± 4.62%) of the examined 81 newborns (one pair of twins) from mothers who were clinically suspicious for vaginal candidiasis. Isolates of the newborns were 100% identical to those of the mothers’ vaginal secretion. Candida albicans was the predominant species identified in the pregnant women (91.67 ± 0.06%) and in the neonates (83.33±8.78%).

Comparative Labelling and Biokinetic Studies of 99mTc-EDTA(Sn) and 99mTc-DTPA(Sn)

1977 ◽  
Vol 16 (01) ◽  
pp. 30-35 ◽  
Author(s):  
N. Agha ◽  
R. B. R. Persson
Keyword(s):  
Complex Formation ◽  
Significant Influence ◽  
Room Temperature ◽  
Ph Value ◽  
Maximum Activity ◽  
Reduction Step ◽  
Labelling Yield ◽  
Different Temperatures ◽  
Kinetics Of

SummaryGelchromatography column scanning has been used to study the fractions of 99mTc-pertechnetate, 99mTcchelate and reduced hydrolyzed 99mTc in preparations of 99mTc-EDTA(Sn) and 99mTc-DTPA(Sn). The labelling yield of 99mTc-EDTA(Sn) chelate was as high as 90—95% when 100 μmol EDTA · H4 and 0.5 (Amol SnCl2 was incubated with 10 ml 99mTceluate for 30—60 min at room temperature. The study of the influence of the pH-value on the fraction of 99mTc-EDTA shows that pH 2.8—2.9 gave the best labelling yield. In a comparative study of the labelling kinetics of 99mTc-EDTA(Sn) and 99mTc- DTPA(Sn) at different temperatures (7, 22 and 37°C), no significant influence on the reduction step was found. The rate constant for complex formation, however, increased more rapidly with increased temperature for 99mTc-DTPA(Sn). At room temperature only a few minutes was required to achieve a high labelling yield with 99mTc-DTPA(Sn) whereas about 60 min was required for 99mTc-EDTA(Sn). Comparative biokinetic studies in rabbits showed that the maximum activity in kidneys is achieved after 12 min with 99mTc-EDTA(Sn) but already after 6 min with 99mTc-DTPA(Sn). The long-term disappearance of 99mTc-DTPA(Sn) from the kidneys is about five times faster than that for 99mTc-EDTA(Sn).

Rhenium-188 Labeled Hydroxyapatite and Rhenium-188 Sulfur Colloid

1997 ◽  
Vol 36 (02) ◽  
pp. 71-75 ◽  
Author(s):  
S. Glatz ◽  
S. N. Reske ◽  
K. G. Grillenberger
Keyword(s):  
Synovial Fluid ◽  
Ph Value ◽  
Surgical Removal ◽  
Radiation Synovectomy ◽  
Sulfur Colloid ◽  
Target Organs ◽  
Aseptic Conditions ◽  
In Vitro Stability ◽  
Potential Use

Summary Aim: One therapeutic approach to rheumatoid arthritis and other inflammatory arthropathies besides surgical removal of inflamed synovium is radiation synovectomy using beta-emitting radionuclides to destroy the affected synovial tissue. Up to now the major problem associated with the use of labeled particles or colloids has been considerable leakage of radionuclides from the injected joint coupled with high radiation doses to liver and other non target organs. In this study we compared 188Re labeled hydroxyapatite particles and 188Re rhenium sulfur colloid for their potential use in radiation synovectomy. Methods: To this end we varied the labeling conditions (concentrations, pH-value, heating procedure) and analyzed the labeling yield, radiochemical purity, and in vitro stability of the resulting radiopharmaceutical. Results: After optimizing labeling conditions we achieved a labeling yield of more than 80% for 188Re hydroxyapatite and more than 90% for the rhenium sulfur colloid. Both of the radiopharmaceuticals can be prepared under aseptic conditions using an autoclav for heating without loss of activity. In vitro stability studies using various challenge solutions (water, normal saline, diluted synovial fluid) showed that 188Re labeled hydroxyapatite particles lost about 80% of their activity within 5 d in synovial fluid. Rhenium sulfur colloid on the other hand proved to be very stable with a remaining activity of more than 93% after 5 d in diluted synovial fluid. Conclusion: These in vitro results suggest that 188Re labeled rhenium sulfur colloid expects to be more suitable for therapeutic use in radiation synovectomy than the labeled hydroxyapatite particles.

Influence of saliva pH-value on the ratio of amphetamine saliva to serum concentration

2019 ◽  
Author(s):  
C Wohkittel ◽  
M Romanos ◽  
A Diehl ◽  
P Högger ◽  
M Gerlach
Keyword(s):  
Serum Concentration ◽  
Ph Value
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