scholarly journals Döderlein. Die Scheidensecretuntersuchungen. (Centralblatt für gynäkologie, No. I, 1894). Examination of vaginal secretions

2020 ◽  
Vol 8 (4) ◽  
pp. 387-388
Author(s):  
V. Stroganov

In the beginning, D. is reviewing the results of studies by Burguburu, Williams, and Burckhardt. These results are quite similar to those presented by the author in his monograph Vaginal secretion and its significance in the development of puerperal fever. Then D. proceeds to the analysis of the above article by Krnig. The last day about the constant acidity of the vaginal secretion (which does not agree with the research of Dderlin and others) he explains by the property of the applied sensitive reactive papers, as well as by the amphoteric reaction.

1985 ◽  
Vol 105 (2) ◽  
pp. 255-262 ◽  
Author(s):  
E. Steel

ABSTRACT Male hamsters were tested for their interest in females on different days of the oestrous cycle. Behaviour of males towards novel females was measured and (after exposure to vaginal secretion) towards females that matched or did not match that vaginal odour. Because pro-oestrous (day 4) females lay trails of vaginal secretion and will become receptive within a few hours, it was predicted that males would show more interest in day 4 than in other dioestrous females. While males showed no preference for novel, pro-oestrous females over dioestrous females, after pre-exposure to odour, their response to females was determined by the cycle day of the vaginal secretion to which they had been exposed. Males pre-exposed to vaginal odour from females carrying large implants of oestrogen preferred to spend more time with females who matched that vaginal odour than mismatching females and to sniff them more. This preference was not seen if the females carried small oestrogen implants or had no replacement oestrogen. This suggests that pro-oestrous females (who are known to have high circulating levels of oestrogen) can, by means of their scent-marking behaviour, attract and keep males nearby until they become receptive. J. Endocr. (1985) 105, 255–262


1998 ◽  
Vol 72 (6) ◽  
pp. 5137-5145 ◽  
Author(s):  
Earl L. Parr ◽  
Margaret B. Parr

ABSTRACT This investigation evaluated immunity to vaginal herpes simplex virus type 2 (HSV-2) infection after local or parenteral immunization with attenuated HSV-2. Vaginal immunization induced sterilizing immunity against challenge with a high dose of wild-type virus, whereas parenteral immunizations protected against neurologic disease but did not entirely prevent infection of the vagina. Vaginal immunization caused 86- and 31-fold increases in the numbers of immunoglobulin G (IgG) plasma cells in the vagina at 6 weeks and 10 months after immunization, whereas parenteral immunizations did not increase plasma cell numbers in the vagina. Vaginal secretion/serum titer ratios and specific antibody activities in vaginal secretions and serum indicated that IgG viral antibody was produced in the vagina and released into vaginal secretions at 6 weeks and 10 months after vaginal immunization but not after parenteral immunizations. In contrast to the case for plasma cells, the numbers of T and B lymphocytes in the vagina were similar in vaginally and parenterally immunized mice. Also, lymphocyte numbers in the vagina were markedly but similarly increased by vaginal challenge with HSV-2 in both vaginally and parenterally immunized mice. Lymphocyte recruitment to the vagina after virus challenge appeared to involve memory lymphocytes, because it was not observed in nonimmunized mice. Thus, local vaginal immunization with attenuated HSV-2 increased the number of IgG plasma cells in the vagina and increased vaginal secretion/serum titer ratios to 3.0- to 4.7-fold higher than in parenterally immunized groups but caused little if any selective homing of T and B lymphocytes to the vagina.


1958 ◽  
Vol 51 (1) ◽  
pp. 70-71
Author(s):  
M. R. Shalash

1. Fifty buffalo-cows were used for studying the pH of the vaginal secretion at different stages of the sex cycle.2. Highly significant differences were found in the pH value of the vaginal secretions during the different stages of the sex cycle. The average was 7·3 during oestrus, 8·1 during dioestrus and 8·3 during pregnancy.


2020 ◽  
Vol 23 (8) ◽  
pp. 207-211
Author(s):  
Sara Tagliani ◽  
Silvia Ventresca ◽  
Lorenzo Mambelli ◽  
Alessandro Cuppari ◽  
Stefano Missiroli ◽  
...  

The paper describes a case of Pelvic Inflammatory Disease (PID) in a fourteen-year-old girl who presented with salpingitis, low abdominal pain, fever, high inflammation indexes and infection by Chlamydia trachomatis and Gardnerella. As guidelines suggest, she was treated with doxycycline, metronidazole and ceftriaxone and her clinical conditions rapidly improved. PID can develop also in teenagers, especially if sexually active, and it must be differentiated from other causes of acute abdomen. The diagnosis can be based on the presence of pain and on at least one criterion between clinical objectivity (fever, vaginal secretions) and laboratory data (vaginal swab, blood exams, vaginal secretion microscopic analysis). Instrumental exams can support the diagnosis but sometimes only laparoscopy and biopsy can reveal a condition of PID. Adequate antibiotic treatment should be performed to avoid complications over future reproductive life.


2021 ◽  
Vol 36 ◽  
pp. 06008
Author(s):  
Roman Vasiliev ◽  
Sergey Kovalev ◽  
Vyacheslav Trushkin ◽  
Alexey Prusakov ◽  
Vladimir Ponamarev

Genital mycoplasmosis in cows is a disease accompanied by a latent course, which complicates its timely diagnosis and the appointment of specific treatment. This disease may lead to infertility. An obstacle to the introduction of pathogens into the epithelium of the mucous membrane is a variety of defense mechanisms. A study of the state of the protective properties of the vaginal mucosa in healthy and mycoplasma-infected cows was carried out by determining the concentration of hydrogen ions and immunoglobulins in vaginal secretions. The results of the study showed a shift in the reaction of vaginal secretions towards neutrality in mycoplasmosis. Thus, the persistence of mycoplasmas in the mucous membrane of the vagina of cows causes a change in the protective properties of the vaginal secretion, as a result of which conditions are created that promote the activation of pathogenic microflora.


2021 ◽  
Vol 11 (7) ◽  
pp. 2006-2010
Author(s):  
Chuanming Sun ◽  
Rongsheng Zhou ◽  
Lihua Yang

Objective: The health management of pregnant women in late pregnancy is difficult. Once vaginal infection occurs, adverse pregnancy outcomes will occur. The aim of this study was to explore the application value of biostatistics health assessment of matrix metalloproteinases (MMP) in vaginal secretions in late pregnant women with vaginal infection. Methods: A total of 120 late pregnant women with vaginal infection, including vulvovaginal candidiasis (WC) in 70 cases and bacterial vaginosis (BV) in 50 cases, were selected as the experimental group. Another 80 pregnant women with normal vaginal secretion in the same gestational week were randomly selected as the control group. Vaginal soft capsule of mycomycin was used in the treatment. The expression levels of MMP-8 and MMP-9 in vaginal secretions before and after treatment were detected by enzyme-linked immunosorbent assay (ELISA) and smear immunohistochemistry, Results: Both the ELISA and immunohistochemistry analysis showed that the levels of MMP-8 and MMP-9 in the vaginal secretion of experimental group were significantly increased than the data of control group (P < 0.05). After effective intervention, the levels of MMP-8 and MMP-9 were significantly lower than those before treatment (P < 0.05). Conclusion: The late pregnant women with vaginal infection was accompanied by the high level of MMP-8 and MMP-9 in vaginal secretions. Effective intervention will lead the reduction of MMP. Thus, the biostatistics health assessment of MMP is important for the late pregnant women with vaginal infection.


Folia Medica ◽  
2016 ◽  
Vol 58 (2) ◽  
pp. 108-114 ◽  
Author(s):  
Liliya G. Zisova ◽  
Anastasia A. Chokoeva ◽  
Georgi I. Amaliev ◽  
Penka V. Petleshkova ◽  
Tsonka М. Miteva-Katrandzhieva ◽  
...  

AbstractVulvovaginal candidiasis is the second most common cause of vaginitis worldwide (after bacterial candidiasis). Maternal vulvovaginal candidiasis is a major risk factor for Candida colonization and infection of the infant where prognosis depends on different predisposing factors. The aim of this study was to determine the incidence and the etiological structure of vulvovaginal candidiasis in pregnant women and its impact on Candida colonization of newborns.Materials and methods: Samples of vaginal secretions from 80 healthy pregnant women who were clinically suspicious for Candida vaginitis were collected within 48 hours before delivery. Samples for probable Candida colonization from the oral mucosa and feces were collected from their newborns within 47-72 hours after birth. Samples were plated on Sabouraud agar, followed by species identification by API Candida yeast assay.Results: Twenty-three (28.75 ± 5.06%) of the evaluated pregnant women were positive for Candida spp. Positive samples for Candida colonization were found in 18 (22.22 ± 4.62%) of the examined 81 newborns (one pair of twins) from mothers who were clinically suspicious for vaginal candidiasis. Isolates of the newborns were 100% identical to those of the mothers’ vaginal secretion. Candida albicans was the predominant species identified in the pregnant women (91.67 ± 0.06%) and in the neonates (83.33±8.78%).


Author(s):  
Sarah A. Luse

In the mid-nineteenth century Virchow revolutionized pathology by introduction of the concept of “cellular pathology”. Today, a century later, this term has increasing significance in health and disease. We now are in the beginning of a new era in pathology, one which might well be termed “organelle pathology” or “subcellular pathology”. The impact of lysosomal diseases on clinical medicine exemplifies this role of pathology of organelles in elucidation of disease today.Another aspect of cell organelles of prime importance is their pathologic alteration by drugs, toxins, hormones and malnutrition. The sensitivity of cell organelles to minute alterations in their environment offers an accurate evaluation of the site of action of drugs in the study of both function and toxicity. Examples of mitochondrial lesions include the effect of DDD on the adrenal cortex, riboflavin deficiency on liver cells, elevated blood ammonia on the neuron and some 8-aminoquinolines on myocardium.


2019 ◽  
Vol 62 (6) ◽  
pp. 1775-1786 ◽  
Author(s):  
Lucía I. Méndez ◽  
Gabriela Simon-Cereijido

Purpose This study investigated the nature of the association of lexical–grammatical abilities within and across languages in Latino dual language learners (DLLs) with specific language impairment (SLI) using language-specific and bilingual measures. Method Seventy-four Spanish/English–speaking preschoolers with SLI from preschools serving low-income households participated in the study. Participants had stronger skills in Spanish (first language [L1]) and were in the initial stages of learning English (second language [L2]). The children's lexical, semantic, and grammar abilities were assessed using normative and researcher-developed tools in English and Spanish. Hierarchical linear regressions of cross-sectional data were conducted using measures of sentence repetition tasks, language-specific vocabulary, and conceptual bilingual lexical and semantic abilities in Spanish and English. Results Results indicate that language-specific vocabulary abilities support the development of grammar in L1 and L2 in this population. L1 vocabulary also contributes to L2 grammar above and beyond the contribution of L2 vocabulary skills. However, the cross-linguistic association between vocabulary in L2 and grammar skills in the stronger or more proficient language (L1) is not observed. In addition, conceptual vocabulary significantly supported grammar in L2, whereas bilingual semantic skills supported L1 grammar. Conclusions Our findings reveal that the same language-specific vocabulary abilities drive grammar development in L1 and L2 in DLLs with SLI. In the early stages of L2 acquisition, vocabulary skills in L1 also seem to contribute to grammar skills in L2 in this population. Thus, it is critical to support vocabulary development in both L1 and L2 in DLLs with SLI, particularly in the beginning stages of L2 acquisition. Clinical and educational implications are discussed.


1980 ◽  
Vol 25 (6) ◽  
pp. 462-463
Author(s):  
NORMAN A. MILGRAM
Keyword(s):  

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