Role of tympanic neurectomy in otalgia

1990 ◽  
Vol 104 (2) ◽  
pp. 114-117 ◽  
Author(s):  
J. A. Cook ◽  
R. M. Irving

AbstractTympanic neurectomy was first described 44 years ago. Although its indications have subsequently increased, it has not become a popular procedure. This paper concentrates on its use in treating otalgia. The history of tympanic neurectomy, the anatomy of the tympanic plexus and the aetiology of otalgia with specific reference to the tympanic plexus are discussed and a case of bilateral otalgia due to glossopharyngeal neuralgia successfully treated by staged, bilateral tympanic neurectomy reported. It is suggested tympanotomy performed under local anaesthesia with selective stimulation of the intra-tympanic nerves may lead to accurate diagnosis and treatment of the various forms of neuralgic otalgia.

Author(s):  
Judith Hayward ◽  
Anju Kulkarni ◽  
Imran Rafi

Advances in genomics have vastly increased our understanding of inherited cancer risk and underlying cancer predisposition syndromes, thereby underpinning a revolution in the diagnosis and treatment of cancer itself. Concern regarding family history of cancer is a common presentation within primary care. This article provides an overview of the role of primary care practitioners in the clinical identification and management of inherited cancer risk within primary care including risk assessment, screening and surveillance. The article will consider management issues, including access to genomic testing and advice on risk-reduction measures. The role of genomics in cancer diagnosis and treatment and future applications will be outlined.


2021 ◽  
Vol 1 (7) ◽  
pp. 479-495
Author(s):  
N. V. Starikova ◽  
A. V. Shurshikova ◽  
M. Y. Shlyakhov

The question of the use of the official labor biography in the 30—40s of the twentieth century as a means of instilling a sacred attitude to work in a Soviet person, a method of non-material stimulation of the production process is considered. The relevance of the study is due to the interest in biography in the context of the history of labor, in the authors’ appeal to the problem of forming a new attitude to work during the period of industrialization and the years of the Great Patriotic War. Attention is paid to the role of periodicals. The results of a comparative analysis of the official and real biography, recovered from the materials of the personal file, are presented. The question is raised about the tasks of the official biography of the Hero of Socialist Labor in this period. The novelty of the research is seen in the attraction of unpublished data from the production archive of the Gorky Railway, in the reconstruction of real biographical data. The authors compare the official and real biographies. The possibility of using heroic biography as a method of non-material stimulation of labor has been proved. The author’s reconstruction of the biography of Ivan Georgievich Makarov — Hero of Socialist Labor is presented. The experience of analytical research of documentary historical sources and their comparison with the narrative tradition is described.


Medicines ◽  
2021 ◽  
Vol 8 (11) ◽  
pp. 67
Author(s):  
Yusuke Watanabe ◽  
Shun Yamazaki ◽  
Hanako Yokoyama ◽  
Shunta Yakubo ◽  
Akihiko Osaki ◽  
...  

Since generalized peritonitis is a fatal disease, accurate diagnosis and treatment are important. In this paper, we report a case of recurrent generalized peritonitis associated with spontaneous urinary bladder rupture (SBR). A 65 year old woman, who underwent radiotherapy 21 years prior, was diagnosed with generalized peritonitis. Although the cause of the generalized peritonitis could not be identified, the patient recovered with conservative treatment in short period. However, recurrent episodes of generalized peritonitis occurred four times. We diagnosed the patient with urinary ascites due to SBR, based on a history of radiotherapy and dysuria. No recurrence of generalized peritonitis had occurred after accurate diagnosis and treatment with long-term bladder catheter placement. Since SBR often occurs as a late complication after radiotherapy, it is difficult to diagnose SBR, which leads to delayed treatment. This case and literature review of similar cases suggest that the information of the following might be helpful in the diagnosis of SBR: (i) history of recurrent generalized peritonitis, (ii) pseudo-renal failure, (iii) history of radiotherapy, (iv) dysuria, and (v) increase or decrease of ascites in a short period. It is important to list SBR in the differential diagnosis by knowing the disease and understanding its clinical features. This case and literature review will serve as a reference for future practices.


1977 ◽  
Vol 05 (02) ◽  
pp. 177-179
Author(s):  
László Debreceni

The case history of a patient with thoracic vertebra fracture and following pain syndrome of the inferior limbs is reported. As a result of acupuncture treatment the pain was significantly reduced, but it could be reinduced by stimulation of the B1-31-33 loci during treatment. On needling the connecting locus of the related meridian of the bladder (Ki-6) the pain disappeared; otherwise stimulation of other loci showed a failure to stop the pain induced by the stimulation of B1-31-33 loci. It is remarkable that both the bladder's and the Ki-6 loci belong to the lumbal 4 spinal segment. The problem of the specific role of the acupuncutre loci also is discussed.


1995 ◽  
Vol 104 (11) ◽  
pp. 895-898 ◽  
Author(s):  
Namju Kim ◽  
Soonkwan Hong ◽  
Seayuong Jeon ◽  
Euigee Hwang ◽  
Yang-Gi Min

To investigate the physiological role of substance P innervation (SPI) in the nasal mucosa from inhaled irritant macromolecules, SPI in the rat nasal mucosa was selectively stimulated with capsaicin and the degree of horseradish peroxidase (HRP) permeability across the nasal epithelium was evaluated by enzyme immunoassay or by histochemical electron microscopy. The serum level of HRP was reduced significantly in capsaicin-administered rats compared to control rats along the time course with quantitative analysis of the enzyme immunoassay. Control rats showed heavy permeation of HRP across the epithelium, but capsaicin-administered rats showed weak permeation of HRP across the epithelium with histochemical electron microscopy. The epithelial lining and its tight junctions were left intact as judged by electron microscopy. In conclusion, selective stimulation of SPI of the rat nasal mucosa with capsaicin decreased the epithelial absorption permeability to HRP without compromising the epithelial integrity. These findings imply that the physiological role of capsaicin-sensitive SPI in the rat mucosa is to protect the airway from inhaled irritant macromolecules.


2019 ◽  
Vol 11 (01) ◽  
pp. 091-093
Author(s):  
Manjari Kishore ◽  
Purnima Malhotra ◽  
Minakshi Bhardwaj

AbstractNeuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary neuroendocrine carcinoma of urinary bladder in an adult female with a history of smoking and hematuria. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis and thereby differentiating this tumor from other clinical mimics.


2019 ◽  
Vol 54 (3) ◽  
pp. 691-729
Author(s):  
LEWIS BREMNER

AbstractThis article explores the thoughts and ideas associated with magic-lantern technology in late eighteenth- and early nineteenth-century Japan. Its primary focus is on trends in Japanese thought from the 1770s until the 1820s, with specific reference to the Rangaku (‘Dutch Studies’) movement. The article examines connections between the magic lantern and a wider discourse within Japan on epistemology, knowledge about nature, and the study of the human body, centring upon the device's vital role in the endeavour to understand the workings of the human eye. Through this lens, a fresh perspective is offered on the role of critical analysis in the translation and interpretation of European texts in Tokugawa Japan, as well as on the shifting prominence of empiricism and deductive reasoning in Japanese epistemology. In this way, the history of the magic lantern is used to look beyond the prevailing West-centred narrative of global technological and intellectual development.


2021 ◽  
Vol 19 (1) ◽  
pp. 97-107
Author(s):  
P. Ilkova ◽  
Z. Stoyneva ◽  
N. Dimitrova

Angioedema is a disease characterized by various triggers and an increasing prevalence. The great Greek physician Hippocrates (377-460 BC), considered one of the most outstanding figures in the history of medicine and "Father of the Western Medicine," already used the term oídēma to describe „swelling of organs“. It took many centuries later until the first description of angioedema as a distinct medical entity was minted by Quinсke in 1882. The contemporary perception, defines аngioedema as a transient swelling of the skin or submucosal surface due to increased vascular permeability of small venules. The overlying skin may be normal or mildly erythematous. Over time, many causes and factors that cause or trigger angioedema have been discussed. There are two main types of angioedema without urticarial (histaminergic and nonhistaminergic) as the role of histamine in the pathogenesis of the disease is crucial. Angioedema is a frequent clinical condition that sometimes can be life-threatening. Different types of angioedema can be challenging to distinguish clinically. However, establishing a correct diagnosis is critical as different forms of angioedema require distinct treatment approaches. Implementation of contemporary differential diagnostic approaches could be a prerequisite for an accurate diagnosis, which secures appropriate management strategies are possible.


2018 ◽  
Vol 41 ◽  
Author(s):  
Kevin Arceneaux

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.


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