scholarly journals Determinants and consequences of malnutrition in hospitalized patients at a Norwegian University Hospital

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Marte A. Trollebo ◽  
Ingrid Revheim ◽  
Hanne Rosendahl-Riise ◽  
Mette H. Morken ◽  
Randi J. Tangvik ◽  
...  

AbstractBackground:Malnutrition is a serious condition that is frequent in hospitalized patients even in countries with high healthcare standards, and may affect up to 30% of all hospitalized patients in tertiary hospitals. Malnutrition or risk of malnutrition (hereafter referred to as malnutrition) strongly relate to clinical outcomes and mortality, even after adjustment for age and co-morbidities. There is a great need for improved methods for detecting and treating malnutrition in this population.Objective:Investigate factors that are associated with malnutrition at hospitalization, and provide data on specific nutrient deficiencies that are associated with malnutrition. Analyse the association of malnutrition with nutritional biomarkers, quality of life, disease-related functions and re-hospitalization, morbidity and mortality.Design:The study is s a prospective case-control study including patients from different Departments of a tertiary hospital (Haukeland University Hospital, Bergen, Norway). As part of the patients security programme, all hospitalized patients are routinely screened for nutritional risk using NRS-2002. The result allocates the patient to either the case- or the control group. Included patients undergo extensive examinations; standardized assessments of quality of life, socio-economic status, lifestyle habits, dietary habits and food intake, and anthropometric measurements (mid-upper arm circumference, waist circumference and body composition by bioelectrical impedance analysis). Blood and urine samples are collected to assess nutritional biomarkers related to malnutrition.Results:The study recruitment is ongoing and up to April 2019, 220 patients have been recruited (n = 90 (41%) at nutritional risk, n = 130 (59%) not at nutritional risk. Most of the patients are recruited from the Department of Heart Disease, n = 69 (31%) and Thoracic Medicine, n = 98 (45%). The recruitment of patients faces many challenges, including a high degree of non-participation (about one in four patients), and a high degree of misclassification (patients falsely categorized as ‘not at nutritional risk’).Conclusion:The study is unique due to the integration of patient-derived data on quality of life, food intake, and socio-economic factors with multiple and complementary nutritional biomarkers. A first result from the recruitment period is the need for specification of the specificity and sensitivity of screening tools for malnutrition in hospitals under realistic circumstances. This should ideally be tested in a multicentre study

2021 ◽  
Vol 38 (2) ◽  
Author(s):  
Mira Sonneborn-Papakostopoulos ◽  
Clara Dubois ◽  
Viktoria Mathies ◽  
Mara Heß ◽  
Nicole Erickson ◽  
...  

AbstractCancer-related malnutrition has a high prevalence, reduces survival and increases side effects. The aim of this study was to assess oncology outpatients and risk of malnutrition. Reported symptoms and quality of life (QoL) in patients found to be at risk of malnutrition or malnourished were compared to patients without malnutrition. Using a standardized questionnaire, the European Organization for Research and Treatment of Cancer Questionnaire for Quality of Life and the Mini Nutritional Assessment (MNA), patients in an outpatient cancer clinic undergoing chemotherapy treatment at a German University Hospital were assessed for nutrition, risk of malnutrition and quality of life. Based on the MNA, 39 (45.9%) patients were categorized as malnourished or at risk for malnutrition. Loss of appetite (n = 37.6%, p < 0.001) and altered taste sensation (n = 30,3%, p < 0.001) were the symptoms most frequently associated with reduced food intake. Patients with risk of malnutrition scored lower on the global health status (n = 48.15%, p = 0.001). Side effects of cancer treatments lead to a higher risk of malnutrition and as a consequence lower QoL. These side effects should be addressed more efficiently in cancer care.


2017 ◽  
Vol 46 (6) ◽  
pp. 613-622 ◽  
Author(s):  
Matthias Lidin ◽  
Elin Ekblom-Bak ◽  
Monica Rydell Karlsson ◽  
Mai-Lis Hellénius

Aims: The aim of this study was to evaluate the effects of a structured intervention programme on lifestyle habits and quality of life after six months and one year in participants with increased cardiovascular risk. Methods: Participants aged ≥18 years with increased cardiovascular risk were referred from primary health care and hospitals. The programme was launched at an outpatient clinic in a department of cardiology at a university hospital. It consisted of individual visits to a nurse for a health check-up and lifestyle counselling at baseline, after six months and at one year. In addition, five group sessions – focusing on nicotine, alcohol, physical activity, eating habits, stress, sleep and behavioural change – were offered to the participants and their relatives or friends. Lifestyle habits and quality of life were assessed with questionnaires at baseline, after six months and at one year. Results: One hundred participants (64 women, 36 men, age 58±11 years) were included in the programme. Compared with the baseline, significant and favourable changes in reported lifestyle habits were noted. Exercise levels were higher after one year and sedentary time decreased from 7.4 to 6.3 h/day. Dietary habits improved and the number of participants with a high consumption of alcohol decreased. Quality of life improved after one year. Conclusions: Participating in a structured lifestyle programme resulted in improved lifestyle habits and quality of life over one year in people with increased cardiovascular risk. Components such as an inter-professional teamwork, a focus on lifestyle rather than the disease, and combining individual visits and group sessions, might be central to the positive outcome of the programme.


2018 ◽  
Vol 132 (3) ◽  
pp. 202-206 ◽  
Author(s):  
J S Phillips ◽  
J Fitzgerald ◽  
D Phillis ◽  
A Underwood ◽  
I Nunney ◽  
...  

AbstractObjective:To determine the effectiveness of vestibular rehabilitation using the Wii Fit balance platform, in adults with dizziness.Methods:A single-site prospective clinical trial was conducted in a university hospital in the UK. Forty patients with dizziness, who would normally be candidates for vestibular rehabilitation, were identified and considered as potential participants. Participants were randomised into either the treatment group (the Wii Fit group) or the control group (standard customised vestibular rehabilitation protocol). Participants were assessed over a 16-week period using several balance and quality of life questionnaires.Results:Both exercise regimes resulted in a reduction of dizziness and an improvement in quality of life scores over time, but no statistically significant difference between the two interventions was identified.Conclusion:This pilot study demonstrated that use of the Wii Fit balance platform resulted in a statistically significant improvement in balance function and quality of life. Furthermore, outcomes were comparable to a similar group of individuals following a standard customised vestibular rehabilitation protocol. The study provides useful information to inform the design and execution of a larger clinical trial.


Author(s):  
Wen-Xia Lan ◽  
Zhe Li

IntroductionTo investigate the effect of nurse-led multidisciplinary cooperation in the early screening and protection of fecal water dermatitis in hospitalized patients with enterostomy.Material and methodsAn enterostomy management team led by nurses with multidisciplinary cooperation was established to investigate the current situation of fecal water dermatitis in patients with enterostomy in our hospital, and the causes of fecal water dermatitis were analyzed. Based on the evidence-based results, the management plan for the prevention of fecal water dermatitis in patients with enterostomy was implemented.ResultsThe incidence of fecal water dermatitis in patients with enterostomy decreased from 45.56% to 20.73%, the screening rate of nutritional risk for patients with enterostomy increased from 45.57% to 97.56%, the accuracy of stoma positioning by nurses was increased from 65.82% to 98.78%, the incidence of basement warping in enterostomy was decreased from 29.80% to 1.95%, the incidence of fecal water leakage decreased from 50.76% to 22.53%, the one-hour leakage rate of stoma basement increased from 4.48% to 97.29%, the awareness rate of patients' related knowledge increased from 43.03% to 80.48%, and the average score of self-care ability of patients (family members) increased from 99.5 to 126.7, Patients' mean quality of life scores increased from 80.73 to 98.57, and patients' mean self-efficacy scores increased from 78.34 to 99.26.The differences in the above indicators were statistically significant (P < 0.01).ConclusionsNurse-led multidisciplinary cooperation can improve early screening and protection of fecal water dermatitis in hospitalized patients with enterostomy and improve the quality of life of patients.


2021 ◽  
Vol 9 ◽  
Author(s):  
Gabriela Markova ◽  
Lukas Houdek ◽  
Zuzana Kocabova

In the present study we examined the positive effects of a healthcare clown intervention on children undergoing surgeries, and the role parent-child relationships may play in their effectiveness. Children between 5 and 12 years, who were scheduled to undergo elective surgical procedures in a large university hospital, were randomly assigned to an intervention group (IG; n = 35) that was visited by a healthcare clown, and a control group (CG; n = 27) that received treatment as usual (i.e., company of parents before the surgery). Children in both groups were videotaped and the videos were later used to rate their activity, arousal, emotional expressivity, and vocalizations. Additionally, children and parents rated their mood and perceived quality of life at several points during the procedure, and parents reported their perceptions of the relationship with their children. Results showed that children in the IG showed more positive emotions and vocalizations than children in the CG. Parents of children in the IG also reported more positive mood than parents of children in the CG. In contrast, children in the CG reported higher quality of life than children in the IG. Importantly, analyses showed considerable effects of the parent-child relationship on all outcome measures. Results of the present study demonstrate that a healthcare clown intervention had some positive effects on behaviors and mood of hospitalized children and their parents. Importantly, our findings also suggest that we need to consider the pre-existing “relationship microcosmos” that the clowns enter when assessing their effectiveness in the hospital.


2019 ◽  
Vol 5 (2) ◽  
pp. 187-195
Author(s):  
Šárka Vévodová ◽  
Filip Havelka ◽  
Jiří Vévoda ◽  
Bronislava Grygová

Introduction: Psoriasis is a chronic skin disease characterized by scaly patches affecting approximately 2-5% of the population. The disease has a negative impact on quality of life and, therefore, psoriatic patients often develop depression. Our work deals with quality of life and depression in psoriasis sufferrers and strives to determine the correlation between their quality of life and depression. Methods: The research took place in the University Hospital Olomouc in 2017 and used questionnaires WHOQOL-BREF and BDI-II. 50 patients with psoriasis were chosen randomly. To process the data we used Mann-Whitney test (the level of significance = 5%) and Spearman´s correlation coefficient (the level of significance = 1%). Results: The results proved that psoriasis has a significant impact on quality of life. The scores for the overall life quality as well as for individual domains were significantly lower in psoriatic patients than in the control group (p&lt;0.001). The degree of depression in patients with psoriasis showed statistically significant correlation in all domains of the quality of life. We proved negative correlation in the overall quality of life (rs =- 0.691**), physical condition (rs =-0.499**), social relations (rs =-0.546**), overall health (rs =-0.396**), and environment (rs =-0.386**). Conclusion: With regard to the ascertained negative correlation between psoriasis and depression and lower quality of life of the sufferers compared to the healthy population, it is essential for healthcare professionals to pay attention not only to somatic manifestations of the disease but also to the patients´ mental health.


2020 ◽  
Vol 29 (12) ◽  
pp. 3375-3385
Author(s):  
Bianca Senf ◽  
Kirsten Grabowski ◽  
Natascha Spielmann ◽  
Jens Fettel

Abstract Purpose In this study, we examined distress levels and quality of life (QoL) of patients with hematologic malignancies under treatment in an acute setting. We used external- and self-assessment instruments for distress. Additionally, we investigated the relation between distress and QoL as well as whether highly distressed patients differed from less distressed patients concerning their QoL. Methods A cross-sectional study with patients of the Medical Clinic II of the University Hospital Frankfurt was conducted. One hundred and nine patients were assessed with an expert rating scale and completed self-report questionnaires. Data were exploratively analyzed and group comparisons between patients who scored above the cut-off of the respective screening instruments and those who did not were conducted. Results Patients with hematologic malignancies experience high levels of distress and low QoL. Especially, role and social functioning are affected. Patients suffer most from fatigue, appetite loss, and insomnia. Using established cut-offs, all screening instruments were able to differentiate between patients regarding distress and QoL. Patients scoring above the cut-off were significantly more distressed and had a lower QoL. There was a medium-to-strong correlation between distress and QoL indicators. Conclusion Cancer-specific screening instruments seem to be able to identify treatment needs more specifically. They also allowed a better differentiation concerning QoL. The close link between distress and QoL needs to be recognized to enable a holistic approach to treatment and thereby optimize the quality of treatment.


2021 ◽  
pp. 18-23
Author(s):  
Anatoliy Oparin ◽  
Aleksey Oparin ◽  
Murghuz Murghuzov

The aim of the study: to study the effect of the quality of life on the melatonin content, and at the same time to assess the state of the factors of aggression and protection of the esophageal mucosa in patients with GERD without comorbidities and with concomitant obstructive sleep apnea/hypopnea syndrome (OSAHS). Methods. 45 patients were taken for the study. 23 of them had GERD  concomitant COPD, 22 were with isolated GERD with a non-erosive form. Melatonin levels were determined using the enzyme immunoassay method (ELIZA). Quality of life was assessed using the SF-36 questionnaire. Antioxidant protection of the mucous membrane (protection factor) – was assessed by the activity of superoxide dismutase (SOD). SOD activity in blood serum was determined by calorimetric method. Determination of the DC level was carried out in the blood by the spectrofluorimetric method. Results. The study showed that in patients with GERD with concomitant COPD, there is a significant decrease in the indicators of antioxidant activity and melatonin, both with indicators from the control group and with indicators of patients with GERD without comorbidity. At the same time, in patients with GERD without comorbidities, an increase in the level of DC was observed in comparison with the control group and patients with GERD with concomitant pathology and acidity of gastric juice. When analyzing the indicators of QOL in patients with GERD with concomitant pathology, there is a significantly more pronounced decrease in mental health, role emotional functioning and vitality. Conclusions. It has been established that in patients with GERD in the stage of exacerbation of the disease, there is a statistically significant decrease in QOL indicators with a high degree of reliability, manifesting itself in patients without combined pathology in the spectrum of indicators of the physical component of health, and in patients with GERD with concomitant obstructive sleep syndrome – in the spectrum of the psychological component quality of life. It has been shown that with a decrease in QOL in patients with GERD, the level of melatonin decreases, the decrease in which more clearly increases in patients with concomitant obstructive sleep apnea. Simultaneously with a drop in the level of melatonin in patients with GERD without associated pathology, the aggression factor increases with a high degree of certainty - that is, a decrease in the pH of gastric juice and an increase in the content of DC, while in patients with GERD with concomitant sleep apnea syndrome, the factor decreases with a high degree of certainty. Protection of the esophageal mucosa – (that is, a decrease in SOD activity), which must be taken into account when treating this category of patients.


2016 ◽  
Vol 94 (6) ◽  
pp. 450-454
Author(s):  
Dmitry B. Kolesnikov ◽  
S. I. Rapoport ◽  
L. A. Voznesenskaya ◽  
M. I. Rasulov

Most clinicians consider duodenum ulcer as a psychosomatic disease. Objective: To show the interdependence of this condition and mental disorders and their relation to disturbances of melatonin production . Materials and Methods: 15 patients with seasonal DU and 15 healthy subjects of the control group were examined during 3 years using laboratory, endoscopic, and standard psychodiagnostic methods. Results. It was found that all patients with exacerbation of DU experienced enhanced anxiety, reduced background mood, and impaired quality of life based on general health and mental health scoring scales. The circadian rhythm of melatonin production was markedly distorted throughout the observation period but especially during exacerbations of the disease. Conclusions. The results indicate a high degree of correlation between DU and mental disorders caused by impaired production of melatonin. It suggests common etiological mechanisms of DU and psychosomatic symptom complex.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A M Ibrahim ◽  
A E Shoman ◽  
G E Mady ◽  
A M Hassan ◽  
D H Mohamed

Abstract Background Patients with renal failure had poorer quality of life than patients with other chronic diseases such as heart failure, diabetes mellitus and even cancer which makes them more susceptible to withdraw dialysis treatment. Objectives The study was conducted to implement a health education program for patients with end stage renal disease on hemodialysis and their caregivers at Ain Shams University Hospital and measure its effect on their quality of life. Methods A controlled interventional study was carried out on three phases. A sample of 56 patients on chronic regular hemodialysis and their caregivers (HD) were selected from the two hemodialysis units at Ain Shams university hospital and data were collected at the beginning and after six months of the health education program. Results The intervention group of the patients after the intervention reported significant better quality of life scores than the control group in all the domains except in work status, quality of social interaction, sexual function, social support and patient satisfaction and there were statistically significant increases in the intervention group of the caregivers than the control group in social function, emotional well-being, role emotional and mental component summary scores. Conclusion The health education and individualized nutritional program had a positive effect on many components of quality of life of the hemodialysis patients and their caregivers


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