Single spies and battalions: the clinical epidemiology of mental disorders

1993 ◽  
Vol 23 (4) ◽  
pp. 891-907 ◽  
Author(s):  
Brian Cooper

SynopsisClinical epidemiology, a term that has been variously defined, is used here to refer to a discipline which, commencing with examination and diagnosis of the individual patient who presents in medical practice, proceeds to study the occurrence of similar, possibly connected cases in the local community, and in so doing may provide hypotheses for population-based studies of disease and its risk factors. While the relevance of this discipline to the modern practice of clinical psychiatry remains largely unexplored, its importance in the search for causes of mental disorder is attested by many instances, both historical and more recent, in which the spread or clustering of psychiatric syndromes in populations could be related to nutritional deficiency, infectious disease, the presence of environmental neurotoxins, the social communication of psychopathology or the transmission of abnormal, harmful behaviour patterns within family groups. Observations made in clinical practice have repeatedly served as the starting point for epidemiological investigation of mental disorders, while conversely epidemiological findings have influenced clinical thinking about their classification, diagnosis, prognosis and morbid risk. A review of the relevant literature underlines the need for a keener awareness of environmental risk factors and a fundamentally epidemiological frame of reference in trying to grapple with the aetiological problems of mental disorder.

2021 ◽  
Vol 10 (1) ◽  
pp. e15510110385
Author(s):  
Aline de Sousa Rocha ◽  
Benedita Maryjose Gleyk Gomes ◽  
Roberta Sousa Meneses ◽  
Marcos Antonio Silva Batista ◽  
Rosane Cristina Mendes Gonçalves ◽  
...  

The psychiatric reform that took place in Brazil carries characteristics of other movements that occurred in other parts of the world. The idea common to all movements is the struggle for the rights of the individual in mental suffering, seeking mainly the rupture of the mental model. These changes led to several transformations in the care scenario, for all professions directly linked to the patient. Nursing in turn has experienced and experiences significant changes in the provision of care. The aim of this study is to talk about nursing care for patients affected by mental disorder, making a temporal analysis of how this care occurred and how it presents itself in the current mental health conjuncture. The methodology is of the literature review type, which occurred through research in the databases BIREME, Lilacs, Scielo, BDENF and VHL. For this, the descriptors: nursing care for people with disorders were selected; nursing care for patients with mental disorders. In view of the results, it was evidenced that nurses are an important part of caring for patients with mental disorders, noting that these make up a multidisciplinary team and highlighting that care goes far beyond just caring for the patient, but that it consists mainly in the relationship with the patient's family, in bonding, in the work that aims at social reintegration and often also the family reinsertion of the individual. Profession that needs to undergo constant updates, but has experienced numerous transformations throughout this period of Reformation.


2021 ◽  
pp. jrheum.201251
Author(s):  
Johanna Karlsson Sundbaum ◽  
Elizabeth V. Arkema ◽  
Judith Bruchfeld ◽  
Jerker Jonsson ◽  
Johan Askling ◽  
...  

Objective To investigate risk factors and characteristics of active tuberculosis (TB) in biologics-naïve rheumatoid arthritis (RA) patients. Methods Population-based case-control study using the Swedish Rheumatology Quality Register, the National Patient Register and the Tuberculosis Register to identify RA cases with active TB and matched RA controls without TB 2001-2014. Clinical data were obtained from medical records. TB risk was estimated as adjusted (adj) odds ratios (OR) with 95% confidence intervals (CI) using univariate and multivariable logistic regression analyses. Results After validation of diagnoses, the study included 31 RA cases with TB, and 122 matched RA controls. All except three cases had reactivation of latent TB. Pulmonary TB dominated (84%). Ever use of methotrexate was not associated with increased TB risk (adj OR 0.8; 95% CI 0.3-2.0), whereas ever treatment with leflunomide (adj OR 6.0; 95% CI 1.5-24.6), azathioprine (adj OR 3.8; 95% CI 1.1-13.8) and prednisolone (adj OR 2.4 (95% CI 1.0-5.9) was. There were no significant differences of maximum dose of prednisolone, treatment duration with prednisolone before TB, or cumulative dose of prednisolone the year before TB diagnosis between cases and controls. Obstructive pulmonary disease was associated with an increased TB risk (adj OR 3.9; 95% CI 1.4-10.7). Conclusion Several RA-associated factors may contribute to the increased TB risk in biologics-naïve RA patients, making risk of TB activation difficult to predict in the individual patient. To further decrease TB in RA patients, the results suggest that screening for latent TB should also be considered in biologics-naïve patients.


2021 ◽  
Author(s):  
Jasmina Veljković ◽  

The family as a living system is an organizedand permanent whole with changing patterns of human behavior, ie the family is the first life and social environment in which the child finds himself and acquires the first experiences that form the starting point of the overall development of the individual. In addition to the family, the time that the child spends in school is relatively long, and accordingly, she manages to achieve her influence on the development and formation of the student's personality. The cooperation established between the family and the school can contribute to both parties in different ways, improving the general atmosphere, the school climate and improving the work of teachers and providing support for the development of the family and parenting skills. By studying the relevant literature, we want to determine the importance of cooperation between the family and the school for the development of students' personalities, which is also the basic goal. The paper uses the historical method, as the basic method of historical research and analysis of the content of pedagogical documentation.


2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S289-S289
Author(s):  
Maria Christensen ◽  
Carmen Lim ◽  
Sukanta Saha ◽  
Danielle Cannon ◽  
Finley Presley ◽  
...  

Abstract Background About a third of the world’s population will develop a mental disorder over their lifetime. Having a mental disorder is a huge burden in health loss and cost for the individual, but also for society because of treatment cost, production loss and caregivers’ cost. The objective of this study is to synthesize the international published literature on the economic burden of mental disorders. Methods Systematic literature searches were conducted in the databases PubMed, Embase, Web of Science, EconLit, NHS York Database and PsychInfo using key terms for cost and mental disorders. Searches were restricted to 1980 until May 2019. The inclusion criteria were: (1) cost-of-illness studies or cost-analyses; (2) diagnosis of at least one mental disorder (3) samples based on the general population; (4) outcome in monetary units. 13,640 publications were screened by their title/abstract and 439 articles were full-text screened by two independent reviewers. 113 articles were included from the systematic searches and 31 articles from snowball searching, giving a total of 144 included articles. Of these, 41 studies had estimates of the economic burden among people with schizophrenia. Results Information about diagnosis, diagnostic criteria, sample size, age, sex, data sources, study perspective, study period, costing approach, cost categories, discount rate and production loss method and cost unit was extracted. The preliminary results show a substantial variety in the used perspective, methodology, costs components and outcomes in the included studies. An online tool is under development enabling the reader to explore the published information on costs by type of mental disorder, subgroups, country, methodology, and study quality. Discussion To the best of our knowledge, this is the first systematic review synthesizing the economic cost of mental disorders worldwide. The paper will provide an important and comprehensive overview over the economic burden of mental disorders, and the output from this review will inform policy-making.


2006 ◽  
Vol 40 (10) ◽  
pp. 882-888 ◽  
Author(s):  
Kate M. Scott ◽  
Mark A. Oakley Browne ◽  
Magnus A. Mcgee ◽  
J. Elisabeth Wells ◽  

Objective: To estimate the prevalence of chronic physical conditions, and the risk factors for those conditions, among those with 12 month mental disorder; to estimate the prevalence of 12 month mental disorder among those with chronic physical conditions. Method: A nationally representative face-to-face household survey was carried out in October 2003 to December 2004 with 12 992 participants aged 16 years and over, achieving a response rate of 73.3%. Mental disorders were measured with the World Mental Health version of the Composite International Diagnostic Interview (CIDI 3.0). Physical conditions were self-reported. All associations are reported adjusted for age and sex. Results: People with (any) mental disorder, relative to those without mental disorder, had higher prevalences of several chronic physical conditions (chronic pain, cardiovascular disease, high blood pressure and respiratory conditions) and chronic condition risk factors (smoking, overweight/obesity, hazardous alcohol use). Around a quarter of people with chronic physical conditions had a comorbid mental disorder compared with 15% of the population without chronic conditions. Significant relationships occurred between some mental disorders and obesity, cardiovascular disease and diabetes for females, but not for males. Conclusions: This paper provides evidence of substantial comorbidity between mental disorders and chronic physical conditions in New Zealand. This should be borne in mind by clinicians working in both mental health and medical services.


2021 ◽  
Vol 15 (1) ◽  
pp. 127-136
Author(s):  
Qiuyue Ma ◽  
Fude Yang ◽  
Botao Ma ◽  
Wenzhan Jing ◽  
Jue Liu ◽  
...  

Abstract Background and Purpose Non-alcoholic fatty liver disease (NAFLD) is becoming the most common liver disease in China. However, the understanding of NAFLD prevalence among Chinese mental disorder inpatients remains insufficient. We aim to investigate the prevalence of NAFLD among mental disorder inpatients in Beijing, China. Methods In this observational study, we included 66,273 mental disorder inpatients between 2014 and 2018, including inpatients with schizophrenia, bipolar disorder, depressive disorder and other mental disorders. Data were obtained from electronic health records of 19 specialized psychiatric hospitals in Beijing. NAFLD was defined by ICD-10 code, excluding other causes of liver disease. We calculated the overall and annual prevalence rates of NAFLD from 2014 to 2018, and compared NAFLD prevalence between sexes, age groups, mental disorders types, antipsychotics use, and comorbidities. Multivariable logistic regression was used to examine risk factors associated with NAFLD. Subgroup analysis was performed in different mental disorder types. Results The prevalence of NAFLD was 17.63% (95% CI 17.34–17.92%) in mental disorder inpatients, increasing from 16.88% in 2014 to 19.07% in 2018. The NAFLD prevalence in participants with schizophrenia (22.44%) was higher than that in participants with bipolar disorder (17.89%), depressive disorder (12.62%), and other mental disorders (12.99%). Women had similar or even higher NAFLD prevalence than men after 50 years. Men, 50–59 years (aOR = 1.71), schizophrenia (aOR = 1.56), bipolar disorder (aOR = 1.47), antipsychotics use (aOR = 1.46), hypertension (aOR = 1.50), diabetes (aOR = 1.83), dyslipidemia (aOR = 2.50) were risk factors for NAFLD in mental disorder inpatients. Conclusion NAFLD was common among Chinese mental disorder inpatients, and increased over years. The prevalence of NAFLD was higher among men, old women, inpatients with schizophrenia, bipolar disorder, antipsychotics, hypertension, diabetes, and dyslipidemia. Fatty liver disease among mental disorder population warrants the attention of psychiatric specialists and health policy-makers.


2010 ◽  
Vol 196 (3) ◽  
pp. 192-199 ◽  
Author(s):  
Madhabika B. Nayak ◽  
Vikram Patel ◽  
Jason C. Bond ◽  
Thomas K. Greenfield

BackgroundThe relationship between partner alcohol use and violence as risk factors for poor mental health in women is unclear.AimsTo describe partner-related and other psychosocial risk factors for common mental disorders in women and examine interrelationships between these factors.MethodData are reported on 821 women aged 18–49 years from a larger population study in north Goa, India. Logistic regression models evaluated the risks for women's common mental disorders and tested for mediation effects in the relationship between partner alcohol use and these disorders.ResultsExcessive partner alcohol use increased the risk for common mental disorders two- to threefold. Partner violence and alcohol-related problems each partially mediated the association between partner excessive alcohol use and these mental disorders. Women's own violence-related attitudes were also independently associated with them.ConclusionsPartner alcohol use, partner violence and women's violence-related attitudes must be addressed to prevent and treat common mental disorders in women.


2012 ◽  
Vol 28 (10) ◽  
pp. 1854-1866 ◽  
Author(s):  
Anadergh Barbosa-Branco ◽  
Ute Bültmann ◽  
Ivan Steenstra

This study aims to determine the prevalence and duration of sickness benefit claims due to mental disorders and their association with economic activity, sex, age, work-relatedness and income replacement using a population-based study of sickness benefit claims (> 15 days) due to mental disorders in Brazil carried out in 2008. The prevalence of mental disorders was 45.1 claims per 10,000 workers. Prevalence and duration of sickness benefit claims due to mental disorder were higher and longer in workers aged over 40 years. Prevalence of claims was 73% higher in women but duration of sickness benefit claims was longer in men. Prevalence rates for claims differed widely according to economic activity, with sewage, residential care and programming and broadcasting activities showing the highest rates. Claims were deemed to be work-related in 8.5% of cases with mental disorder showing low work-relatedness in Brazil. A wide variation of prevalence and duration between age, economic activity and work-relatedness was observed, suggesting that working conditions are a more important factor in mental disorder work disability than previously assumed.


1999 ◽  
Vol 29 (6) ◽  
pp. 1265-1271 ◽  
Author(s):  
A. S. HENDERSON ◽  
D. H. R. BLACKWOOD

Psychiatric epidemiology is becalmed. Since mid-century, there has been substantial progress in finding risk factors for the common mental disorders of anxiety and depression. This has been almost entirely within a social paradigm. Much has been learned about the effects of interpersonal and other social exposures across the lifespan in contributing to these disorders (Brown & Harris, 1978, 1989; Paykel, 1992; Blazer, 1995; Henderson, 1988, 1999). But the range of possibly causal variables has been narrow: demography, socio-economic status, childhood experiences, recent exposure to adversity and the availability of social support. The dominant paradigm has been environmental exposure, examining how experiences that arise outside the individual may have an enduring impact on mental health. The environment in question has been interpersonal or social. Within this paradigm, no new hypotheses of major significance have emerged in recent years.Epidemiologists have known that the biological domain might be important in aetiology, but for the common mental disorders it has been largely passed over. Properties of the adult brain, whether innate or moulded by environmental exposures, have only rarely been accessible. With the advances in molecular genetics, this is changing (Rutter & Plomin, 1997). For epidemiology, there is now the possibility of bringing molecular genetics into studies of aetiology. Because of the significance of this development, we present a critical assessment of the prospects for population-based research using molecular genetics, the work already reaching publication and the methodological issues that are arising.


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