The effects of stress–tension on depression and anxiety symptoms: evidence from a novel twin modelling analysis

2016 ◽  
Vol 46 (15) ◽  
pp. 3213-3218 ◽  
Author(s):  
C. G. Davey ◽  
C. López-Solà ◽  
M. Bui ◽  
J. L. Hopper ◽  
C. Pantelis ◽  
...  

BackgroundNegative mood states are composed of symptoms of depression and anxiety, and by a third factor related to stress, tension and irritability. We sought to clarify the nature of the relationships between the factors by studying twin pairs.MethodA total of 503 monozygotic twin pairs completed the Depression Anxiety Stress Scales (DASS), an instrument that assesses symptoms of depression, anxiety and stress–tension. We applied a recently developed twin regression methodology – Inference about Causation from Examination of FAmiliaL CONfounding (ICE FALCON) – to test for evidence consistent with the existence of ‘causal’ influences between the DASS factors.ResultsThere was evidence consistent with the stress–tension factor having a causal influence on both the depression (p < 0.0001) and anxiety factors (p = 0.001), and for the depression factor having a causal influence on the anxiety factor (p < 0.001).ConclusionsOur findings suggest a critical role for stress–tension in the structure of negative mood states, and that interventions that target it may be particularly effective in reducing depression and anxiety symptoms.

1990 ◽  
Vol 66 (2) ◽  
pp. 509-510 ◽  
Author(s):  
Kathleen Moore ◽  
Robb Stanley ◽  
Graham Burrows

The Profile of Mood States was administered to 90 Australian women, 30 depressed, 30 anxious, and 30 nonpsychiatric controls. Both clinical groups scored higher than the McNair, Lorr, and Droppleman (1971) normative samples on the negative mood states and scored lower on Vigor. The means for these groups are presented and compared with the 1971 normative data of McNair, Lorr, and Droppleman.


2021 ◽  
pp. 026988112097233
Author(s):  
Richard J Xia ◽  
Thomas Chao ◽  
Divya Patel ◽  
Gillinder Bedi

Background: Aspects of the canonical stress response differ in stimulant, opioid, and alcohol users relative to controls, and dysregulated responses to stress may contribute to continued use of these drugs. Little prior research has focused on stress responses in regular cannabis smokers. We assessed responses to a standardized laboratory social stress assay (the Trier Social Stress Task; TSST) in regular cannabis smokers (CANs) compared with controls (CONs). Methods: Healthy, non-treatment-seeking adult CANs (⩾4×/week; smoking cannabis as usual) and demographically matched CONs completed the TSST. Outcome measures were subjective mood, heart rate, and salivary cortisol. Results: Nineteen CANs (1 female) and 20 CONs (2 female) participated; groups were matched on trauma exposure, sex, race, and age. CANs smoked cannabis 6.4 ± 1.1 days/week. Eight CANs and one CON smoked tobacco cigarettes daily. Overall, the TSST produced expected increases in anxiety, negative mood states, cortisol, and heart rate. CANs had blunted subjective response to stress relative to CONs, but they did not differ in physiological (cortisol and cardiovascular) stress responding. Conclusion: These results indicate that CANs have blunted mood responses to social stress, but normative physiological stress responding. Observed differences could be due to residual effects of cannabis, reluctance to endorse negative mood states, or to issues related to identifying (i.e., emotional identification) or feeling (i.e., interoception) stress-related affective states. Further research is warranted to characterize the mechanisms of these differences and assess implications for daily functioning and treatment outcomes.


2020 ◽  
Author(s):  
Anita Lungu ◽  
Janie Jihee Jun ◽  
Okhtay Azarmanesh ◽  
Yan Leykin ◽  
Connie E-Jean Chen

BACKGROUND The past few decades saw considerable advances in research and dissemination of evidence-based psychotherapies, yet available treatment resources are not able to meet the high need for care for individuals suffering from depression or anxiety. Blended care psychotherapy, which combines the strengths of therapist-led and internet interventions, can narrow this gap and be clinically effective and efficient, but has rarely been evaluated outside of controlled research settings. OBJECTIVE This study evaluated the effectiveness of a blended care intervention (video-based cognitive behavior therapy and internet intervention) under real-world conditions. METHODS This is a pragmatic retrospective cohort analysis of 385 participants with clinical range depression and/or anxiety symptoms at baseline, measured using Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7), who enrolled in blended care psychotherapy treatment. Participants resided in the United States and had access to the blended care intervention as a mental health benefit offered through their employers. Levels of depression and anxiety were tracked throughout treatment. Hierarchical linear modeling was used to examine the change in symptoms over time. The effects of age, gender, and providers on participants’ symptom change trajectories were also evaluated. Paired sample t-tests were also conducted, and rates of positive clinical change and clinically significant improvement were calculated. RESULTS The average depression and anxiety symptoms at 6 weeks after the start of treatment were 5.94 and 6.57, respectively. There were significant linear effects of time on both symptoms of depression and anxiety (β=–.49, <i>P</i>&lt;.001 and β=–.64, <i>P</i>&lt;.001). The quadratic effect was also significant for both symptoms of depression and anxiety (β=.04, P&lt;.001 for both), suggesting a decelerated decrease in symptoms over time. Approximately 73% (n=283) of all 385 participants demonstrated reliable improvement, and 83% (n=319) recovered on either the PHQ-9 or GAD-7 measures. Large effect sizes were observed on both symptoms of depression (Cohen d=1.08) and of anxiety (d=1.33). CONCLUSIONS Video blended care cognitive behavioral therapy interventions can be effective and efficient in treating symptoms of depression and anxiety in real-world conditions. Future research should investigate the differential and interactive contribution of the therapist-led and digital components of care to patient outcomes to optimize care.


2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Kaiyi Han

The aim of this study was to confirm if there was a correlation between trait mindfulness, negative mood states, and stress. Our study is based on the assumption that practicing mindfulness did have the efficacy and ability to regulate negative emotions and thoughts produced by negativity-inducing external stimuli. A hundred and fifteen individuals (M age = 32.17 years, SD = 8.21, 59 males and 56 females) mostly from Beijing and Shanghai completed a series of measures, which included the Five-Facet Mindfulness Questionnaire (FFMQ), the Profile of Mood States-Brief Questionnaire (POMS-B), and the Stress Self-Perception Scale. After analyzing the collected data with SPSS 22.0, results showed that trait mindfulness has a significant relation with both negative mood states and stress, the relation being negative mood states and stress having a negative correlation to mindfulness and vice versa. This study verified the ability of mindfulness to stabilize and regulate negative emotions like depression and indicated the importance of practicing mindfulness as a way to cope with negativity-inducing stimuli and associated thoughts and emotions. Limitations and future research directions are discussed.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S45-S45
Author(s):  
Courtney J Bolstad ◽  
Anisha L Thomas ◽  
Michael R Nadorff

Abstract Symptoms of insomnia are associated with symptoms of depression and anxiety in older adults, yet less is known about the impact of specific forms of insomnia (i.e. onset, maintenance, and terminal insomnia). We explored how insomnia type predicted symptoms of anxiety and depression in older adults (n = 133; mean age 69, range 65-89). We hypothesized that onset and maintenance insomnia would have stronger relations to depression and anxiety than terminal insomnia. Regression analyses indicated that onset insomnia was the only significant predictor of anxiety symptoms, and maintenance was the only significant predictor of depressive symptoms. Thus, our findings suggest that despite overlap between depression and anxiety, insomnia may have different mechanisms of affecting each disorder. Implications for the treatment of anxiety and depressive symptoms by addressing insomnia problems will be discussed.


2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Arndt Büssing ◽  
Anne-Gritli Wirth ◽  
Knut Humbroich ◽  
Kathrin Gerbershagen ◽  
Sebastian Schimrigk ◽  
...  

The aim of this cross-sectional anonymous survey with standardized questionnaires was to investigate which resources to cope were used by patients with multiple sclerosis (MS). We focussed on patients' conviction that their faith might be a strong hold in difficult times and on their engagement in different forms of spirituality. Consecutively 213 German patients (75% women; mean age 43 ± 11 years) were enrolled. Fifty-five percent regarded themselves as neither religious nor spiritual (R−S−), while 31% describe themselves as religious. For 29%, faith was a strong hold in difficult times. This resource was neither related to patients' EDSS scores, and life affections, fatigue, negative mood states, life satisfaction nor to Positive attitudes. Instead it was moderately associated with a Reappraisal strategy (i.e., and positive interpretation of illness) and experience of gratitude/awe. Compared to spiritual/religious patients, R−S− individuals had significantly (P<.0001) lower Reappraisal scores and lower engagement in specific forms of spiritual practices. The ability to reflect on what is essential in life, to appreciate and value life, and also the conviction that illness may have meaning and could be regarded as a chance for development was low in R−S− individuals which either may have no specific interest or are less willing to reflect these issues.


1983 ◽  
Vol 7 (3) ◽  
pp. 327-331 ◽  
Author(s):  
Patricia B. Sutker ◽  
Julian M. Libet ◽  
Albert N. Allain ◽  
Carrie L. Randall

2013 ◽  
Vol 2 (2) ◽  
pp. 113-119 ◽  
Author(s):  
Dianah Rodrigues ◽  
Yvonne Tran ◽  
Nirupama Wijesuriya ◽  
Rebecca Guest ◽  
James Middleton ◽  
...  

2016 ◽  
Vol 29 (3) ◽  
pp. 697-710 ◽  
Author(s):  
Evin Aktar ◽  
Cristina Colonnesi ◽  
Wieke de Vente ◽  
Mirjana Majdandžić ◽  
Susan M. Bögels

AbstractThe present study investigated the associations of mothers' and fathers' lifetime depression and anxiety symptoms, and of infants' negative temperament with parents' and infants' gaze, facial expressions of emotion, and synchrony. We observed infants' (age between 3.5 and 5.5 months, N = 101) and parents' gaze and facial expressions during 4-min naturalistic face-to-face interactions. Parents' lifetime symptoms of depression and anxiety were assessed with clinical interviews, and infants' negative temperament was measured with standardized observations. Parents with more depressive symptoms and their infants expressed less positive and more neutral affect. Parents' lifetime anxiety symptoms were not significantly related to parents' expressions of affect, while they were linked to longer durations of gaze to parent, and to more positive and negative affect in infants. Parents' lifetime depression or anxiety was not related to synchrony. Infants' temperament did not predict infants' or parents' interactive behavior. The study reveals that more depression symptoms in parents are linked to more neutral affect from parents and from infants during face-to-face interactions, while parents' anxiety symptoms are related to more attention to parent and less neutral affect from infants (but not from parents).


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