Longitudinal changes in within-salience network functional connectivity mediate the relationship between childhood abuse and neglect, and mental health during adolescence

2021 ◽  
pp. 1-13
Author(s):  
Divyangana Rakesh ◽  
Nicholas B. Allen ◽  
Sarah Whittle
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Functional Connectivity ◽  
Childhood Abuse ◽  
Childhood Maltreatment ◽  
Resting State Fmri ◽  
Poor Mental Health ◽  
Risk And Resilience ◽  
Abuse And Neglect ◽  
Problematic Substance

Abstract Background Understanding the neurobiological underpinnings of childhood maltreatment is vital given consistent links with poor mental health. Dimensional models of adversity purport that different types of adversity likely have distinct neurobiological consequences. Adolescence is a key developmental period, during which deviations from normative neurodevelopment may have particular relevance for mental health. However, longitudinal work examining links between different forms of maltreatment, neurodevelopment, and mental health is limited. Methods In the present study, we explored associations between abuse, neglect, and longitudinal development of within-network functional connectivity of the salience (SN), default mode (DMN), and executive control network in 142 community residing adolescents. Resting-state fMRI data were acquired at age 16 (T1; M = 16.46 years, s.d. = 0.52, 66F) and 19 (T2; mean follow-up period: 2.35 years). Mental health data were also collected at T1 and T2. Childhood maltreatment history was assessed prior to T1. Results Abuse and neglect were both found to be associated with increases in within-SN functional connectivity from age 16 to 19. Further, there were sex differences in the association between neglect and changes in within-DMN connectivity. Finally, increases in within-SN connectivity were found to mediate the association between abuse/neglect and lower problematic substance use and higher depressive symptoms at age 19. Conclusions Our findings suggest that childhood maltreatment is associated with altered neurodevelopmental trajectories, and that changes in salience processing may be linked with risk and resilience for the development of depression and substance use problems during adolescence, respectively. Further work is needed to understand the distinct neurodevelopmental and mental health outcomes of abuse and neglect.

scholarly journals Emotional abuse and neglect: time to focus on prevention and mental health consequences

2020 ◽  
Vol 217 (5) ◽  
pp. 597-599 ◽  
Author(s):  
Veena Kumari
Keyword(s):  
Mental Health ◽  
Health Outcomes ◽  
Childhood Maltreatment ◽  
Emotional Abuse ◽  
Intervention Studies ◽  
Poor Mental Health ◽  
Mental Health Outcomes ◽  
Health Consequences ◽  
Correlational Research ◽  
Abuse And Neglect

SummaryEmotional abuse and emotional neglect are among the most prevalent of childhood maltreatment types and associated with a range of poor mental health outcomes. We need to move beyond correlational research and shift our focus to sophisticated multimodal studies to fully understand the psychobiological mechanisms underlying these associations and to intervention studies.

scholarly journals Investigating patterns of neural response associated with childhood abuse v. childhood neglect

2019 ◽  
Vol 50 (8) ◽  
pp. 1398-1407 ◽  
Author(s):  
Vanessa Bianca Puetz ◽  
Essi Viding ◽  
Mattia Indi Gerin ◽  
Jean-Baptiste Pingault ◽  
Arjun Sethi ◽  
...  
Keyword(s):  
Childhood Abuse ◽  
Cognitive Processing ◽  
Childhood Maltreatment ◽  
Poor Mental Health ◽  
Self Report ◽  
Childhood Neglect ◽  
Differential Effects ◽  
Increased Risk ◽  
Abuse And Neglect ◽  
Neural Reactivity

AbstractBackgroundChildhood maltreatment is robustly associated with increased risk of poor mental health outcome and changes in brain function. The authors investigated whether childhood experience of abuse (e.g. physical, emotional and sexual abuse) and neglect (physical and emotional deprivation) was differentially associated with neural reactivity to threat.MethodsParticipants were drawn from an existing study and allocated to one of four groups based on self-report of childhood maltreatment experience: individuals with childhood abuse experiences (n = 70); individuals with childhood neglect experiences (n = 87); individuals with combined experience of childhood abuse and neglect (n = 50); and non-maltreated individuals (n = 207) propensity score matched (PSM) on gender, age, IQ, psychopathology and SES. Neural reactivity to facial cues signalling threat was compared across groups, allowing the differential effects associated with particular forms of maltreatment experience to be isolated.ResultsBrain imaging analyses indicated that while childhood abuse was associated with heightened localised threat reactivity in ventral amygdala, experiences of neglect were associated with heightened reactivity in a distributed cortical fronto-parietal network supporting complex social and cognitive processing as well as in the dorsal amygdala. Unexpectedly, combined experiences of abuse and neglect were associated with hypo-activation in several higher-order cortical regions as well as the amygdala.ConclusionsDifferent forms of childhood maltreatment exert differential effects in neural threat reactivity: while the effects of abuse are more focal, the effects of neglect and combined experiences of abuse are more distributed. These findings are relevant for understanding the range of psychiatric outcomes following childhood maltreatment and have implications for intervention.

scholarly journals A Faith to Move Mountains? Childhood Abuse, Religious Change, and Mental Health at Midlife

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 461-461
Author(s):  
Laura Upenieks
Keyword(s):  
Mental Health ◽  
Life Course ◽  
Childhood Abuse ◽  
Childhood Maltreatment ◽  
Well Being ◽  
The United States ◽  
Religious Attendance ◽  
Three Dimensions ◽  
Religious Importance ◽  
The Life Course

Abstract Of all the various forms of adversity experienced during childhood, childhood maltreatment (emotional and physical abuse) is shown to have the largest impacts on mental health and well-being. Yet we still have a limited understanding of why some victims of early maltreatment suffer immense mental health consequences later on in the life course, while others are able to cushion the blow of these early insults. Using two waves of data from the National Survey of Midlife Development in the United States (MIDUS), this study considers change in religiosity as a buffer across three dimensions for victims of childhood abuse: religious importance, attendance, and the specific act of seeking comfort through religion. Results suggest that increases in religious comfort during adulthood are positively associated with adult mental health for victims of abuse, while decreases in religious comfort over time were associated with worse mental health. Changes in religious attendance and religious importance were not significant associated with mental health for victims of abuse. Taken together, my results show that the stress-moderating effects of religion for victims of childhood maltreatment are contingent on the stability or increases or decreases in religiosity over the life course, which has been overlooked in previous work.

Young construction workers: substance use, mental health, and workplace psychosocial factors

2017 ◽  
Vol 10 (4) ◽  
pp. 155-168 ◽  
Author(s):  
Ken Pidd ◽  
Vinita Duraisingam ◽  
Ann Roche ◽  
Allan Trifonoff
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Substance Use ◽  
Psychological Distress ◽  
Construction Industry ◽  
Psychosocial Factors ◽  
Job Stress ◽  
Poor Mental Health ◽  
Psychological Wellbeing ◽  
Content Type

Purpose Young Australian workers are at elevated risk of mental health and alcohol and other drug related problems. The purpose of this paper is to examine the relationship between alcohol and drug (AOD) use, psychological wellbeing, and the workplace psychosocial environment among young apprentices in the construction industry. Design/methodology/approach A cross-sectional survey of a cohort of 169 construction industry apprentices in their first year of training was undertaken. The survey included measures of psychological distress (K10), quantity/frequency measures of alcohol and illicit drug use, and workplace psychosocial factors. Findings Construction industry apprentices are at elevated risk of AOD related harm and poor mental health. Levels of psychological distress and substance use were substantially higher than age/gender equivalent Australian population norms. Job stress, workplace bullying, and general social support accounted for 38.2 per cent of the variance in psychological distress. General social support moderated the effects of job stress and bullying on psychological distress. Substance use was not associated with psychological distress. However, workplace social support accounted for 2.1 per cent of the variance in AUDIT-C scores, and 2.0 per cent of the variance in cannabis use. Workplace bullying explained 2.4 per cent of the variance in meth/amphetamine use. Practical implications Construction trades apprentices are a high-risk group for harmful substance use and poor mental health. Study results indicate that psychosocial wellbeing interventions are warranted as a harm reduction strategy. Originality/value This is the first study of its kind to describe a cohort of Australian construction trade apprentices in terms of their substance use and psychological wellbeing. The study shows workplace psychosocial factors may predict young workers psychological wellbeing.

scholarly journals Cyberbullying victimisation and internalising and externalising problems among adolescents: the moderating role of parent–child relationship and child's sex

2018 ◽  
Vol 29 ◽  
Author(s):  
H. Sampasa-Kanyinga ◽  
K. Lalande ◽  
I. Colman
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Psychological Distress ◽  
Poor Mental Health ◽  
Self Report ◽  
Parent Child Relationship ◽  
Child Relationship ◽  
Externalising Problems ◽  
Bullying Victimisation ◽  
Parent Child

Abstract Aims Previous research has found links between cyberbullying victimisation and internalising and externalising problems among adolescents. However, little is known about the factors that might moderate these relationships. Thus, the present study examined the relationships between cyberbullying victimisation and psychological distress, suicidality, self-rated poor mental health and substance use among adolescents, and tested whether parent–child relationship and child's sex would moderate these relationships. Methods Self-report data on experiences of cyberbullying victimisation, self-rated poor mental health, psychological distress, suicidality and substance use were derived from the 2013 Ontario Student Drug Use and Health Survey, a province-wide school-based survey of students in grades 7 through 12 aged 11–20 years (N = 5478). Logistic regression models adjusted for age, sex, ethnicity, subjective socioeconomic status and involvement in physical fighting, bullying victimisation and perpetration at school. Results Cyberbullying victimisation was associated with self-rated poor mental health (adjusted odds ratio (OR) 2.15; 95% confidence interval (CI) 1.64–2.81), psychological distress (OR 2.41; 95% CI 1.90–3.06), suicidal ideation (OR 2.38; 95% CI 1.83–3.08) and attempts (OR 2.07; 95% CI 1.27–3.38), smoking tobacco cigarette (OR 1.96; 95% CI 1.45–2.65), cannabis use (OR 1.82; 95% CI 1.32–2.51), and binge drinking (OR 1.44; 95% CI 1.03–2.02). The association between cyberbullying victimisation and psychological distress was modified by parent–child relationship and child's sex (three-way interaction term p < 0.05). The association between cyberbullying victimisation and psychological distress was much stronger among boys who have a negative relationship with their parents. Conclusions Findings suggest that cyberbullying victimisation is strongly associated with psychological distress in most adolescents with the exception of males who get along well with their parents. Further research using a longitudinal design is necessary to disentangle the interrelationship among child's sex, parent–child relationship, cyberbullying victimisation and mental health outcomes among adolescents in order to improve ongoing mental health prevention efforts.

scholarly journals Normative range parenting and the developing brain: a scoping review of the literature

2019 ◽  
Author(s):  
Madeline Farber ◽  
Dylan Gee ◽  
Ahmad R. Hariri
Keyword(s):  
Mental Health ◽  
Brain Development ◽  
Scoping Review ◽  
Developmental Trajectories ◽  
Future Research ◽  
Risk And Resilience ◽  
Abuse And Neglect ◽  
Brain Structure And Function ◽  
And Function ◽  
The Impact

Studies of early adversity such as trauma, abuse, and neglect highlight the critical importance of quality caregiving in brain development and mental health. However, the impact of normative range variability in caregiving on such biobehavioral processes remains poorly understood. Thus, we lack an essential foundation for understanding broader, population-representative developmental mechanisms of risk and resilience. Here, we conduct a scoping review of the extant literature centered on the question, “Is variability in normative range parenting associated with variability in brain structure and function?” After removing duplicates and screening by title, abstract, and full-text, 23 records were included in a qualitative review. The most striking outcome of this review was not only how few studies have explored associations between brain development and normative range parenting, but also how little methodological consistency exists across published studies. In light of these limitations, we propose recommendations for future research on normative range parenting and brain development. In doing so, we hope to facilitate evidence-based research that will help inform policies and practices that yield optimal developmental trajectories and mental health.

scholarly journals Cyber Sexual Harassment: Prevalence and association with substance use, poor mental health, and STI history among sexually active adolescent girls

2019 ◽  
Vol 75 ◽  
pp. 53-62 ◽  
Author(s):  
Elizabeth Reed ◽  
Marissa Salazar ◽  
Alma I. Behar ◽  
Niloufar Agah ◽  
Jay G. Silverman ◽  
...  
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Sexual Harassment ◽  
Adolescent Girls ◽  
Poor Mental Health ◽  
Sexually Active

scholarly journals Changes in millennial adolescent mental health and health-related behaviours over 10 years: a population cohort comparison study

2019 ◽  
Vol 48 (5) ◽  
pp. 1650-1664 ◽  
Author(s):  
Praveetha Patalay ◽  
Suzanne H Gage
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Depressive Symptoms ◽  
Mental Health Problems ◽  
Poor Mental Health ◽  
Poor Sleep ◽  
Birth Cohorts ◽  
Health Related ◽  
Self Harm ◽  
Social Behaviours

Abstract Background There is evidence that mental health problems are increasing and substance use behaviours are decreasing. This paper aimed to investigate recent trends in mental ill health and health-related behaviours in two cohorts of UK adolescents in 2005 and 2015. Methods Prevalences in mental health (depressive symptoms, self-harm, anti-social behaviours, parent-reported difficulties) and health-related behaviours (substance use, weight, weight perception, sleep, sexual intercourse) were examined at age 14 in two UK birth cohorts; Avon Longitudinal Study of Parents and Children (ALSPAC, N = 5627, born 1991–92) and Millennium Cohort Study (MCS, N = 11 318, born 2000–02). Prevalences and trend estimates are presented unadjusted and using propensity score matching and entropy balancing to account for differences between samples. Results Depressive symptoms (9% to 14.8%) and self-harm (11.8% to 14.4%) were higher in 2015 compared with 2005. Parent-reported emotional difficulties, conduct problems, hyperactivity and peer problems were higher in 2015 compared with 2005 (5.7–8.9% to 9.7–17.7%). Conversely, substance use (tried smoking, 9.2% to 2.9%; tried alcohol, 52.1% to 43.5%, cannabis, 4.6% to 3.9%), sexual activity (2% to 0.9%) and anti-social behaviours (6.2–40.1% to 1.6–27.7%) were less common or no different. Adolescents in 2015 were spending less time sleeping (&lt;8 h 5.7% to 11.5%), had higher body mass index (BMI) (obese, 3.8% to 7.3%) and a greater proportion perceived themselves as overweight (26.5% to 32.9%). The findings should be interpreted bearing in mind limitations in ability to adequately harmonize certain variables and account for differences in attrition rates and generalizability of the two cohorts. Conclusions Given health-related behaviours are often cited as risk factors for poor mental health, our findings suggest relationships between these factors might be more complex and dynamic in nature than currently understood. Substantial increases in mental health difficulties, BMI and poor sleep-related behaviours highlight an increasing public health challenge.

scholarly journals Child maltreatment (neglect and abuse) in the 1958 birth cohort: an overview of associations with developmental trajectories and long-term outcomes

2020 ◽  
Vol 11 (4) ◽  
pp. 431-458
Author(s):  
Chris Power ◽  
Leah Li ◽  
Snehal M. Pinto Pereira
Keyword(s):  
Mental Health ◽  
Sexual Abuse ◽  
Child Maltreatment ◽  
Birth Cohort ◽  
Childhood Abuse ◽  
Physical Functioning ◽  
Childhood Maltreatment ◽  
Cognitive Abilities ◽  
Blood Lipids ◽  
Adult Health

Childhood maltreatment types (neglect and psychological, physical or sexual abuse) are associated with many poor outcomes in adulthood. Yet, research mainly focuses on the cumulative adversity burden rather than specificities and commonalities of associations with adult outcomes and intervening pathways. This overview therefore summarises evidence from several research studies using the 1958 British Birth Cohort on specific maltreatment types, child development trajectories, adult intermediaries and outcomes. About one in five participants were identified as neglected or abused in childhood. Neglect was associated with key dimensions of development: slower height growth, delayed maturation, faster BMI gain, and poorer emotional and cognitive development. Associated adulthood outcomes included harmful behaviours (notably smoking), poorer physical health (shorter height, excess BMI, poorer blood lipids and glucose, poor-rated health and physical functioning), worse mental health, lower socio-economic circumstances (e.g. poorer living conditions) and elevated mortality in mid-adulthood. Childhood abuse associations were less widespread and were often only for specific types: most were unrelated to childhood height and cognitive abilities, but all were associated with poorer child emotional development, adult mental health, smoking, blood lipids and self-rated health. Additionally, physical abuse was associated with faster BMI gain, higher adult BMI, blood glucose, inflammation and mortality in mid-adulthood; sexual abuse with faster BMI gain, higher adult BMI, poor physical functioning at 50y and higher mortality in mid-adulthood. Adult health measures associated with child maltreatment are key predictors of serious disease, disability and death. Therefore, child maltreatment associations with these measures represent an important burden for individuals and society.

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