Prevalence, predictors, and treatment of eating disorders in children: a national study

2021 ◽  
pp. 1-8
Author(s):  
Christina M. Sanzari ◽  
Rachel Y. Levin ◽  
Richard T. Liu
Keyword(s):  
Eating Disorders ◽  
Psychiatric Treatment ◽  
Unmet Need ◽  
Population Based ◽  
National Study ◽  
Treatment Utilization ◽  
Age Group ◽  
Prevalence Rates ◽  
Economic Insecurity ◽  
Cross Sectional

Abstract Background Although the prevalence rates of preadolescent eating disorders (EDs) are on the rise, considerably less is known about the correlates and treatment of EDs in this age group. Clarifying the epidemiology of EDs in preadolescent children is a necessary first step to understand the nature and scope of this problem in this age group. Methods Analysis of data collected in the ABCD Study release 2.0.1. The ABCD cohort was a population-based sample that consisted of 11 721 children ages 9–10 years. Measures included reports of a lifetime and current mental disorders determined using a diagnostic interview for DSM-5 disorders, sociodemographic factors, and psychiatric treatment utilization. Results The lifetime prevalence of EDs was 0.95%. Being Black, multiracial, having unmarried parents, and family economic insecurity were significant predictors for developing an ED. Among psychiatric conditions, the major depressive disorder was most robustly associated with EDs in both cross-sectional and temporal analyses. Only 47.40% of children who had a lifetime ED received some type of psychiatric treatment. EDs were not a significant predictor of psychiatric treatment utilization after accounting for sex, sexual orientation, parent marital status, economic insecurity, and all other psychiatric diagnoses. Conclusions Despite increasing prevalence rates of preadolescent EDs, the current findings suggest that the majority of children with these disorders remain untreated. Devoting increased attention and resources to reaching families of children with EDs with the least means for receiving care, and screening for EDs in children with depression, may be important steps for reducing this unmet need.

scholarly journals Gender differences in the use of atypical antipsychotics in early-onset schizophrenia: a nationwide population-based study in Brazil

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Izabela Fulone ◽  
Marcus Tolentino Silva ◽  
Luciane Cruz Lopes
Keyword(s):  
Gender Differences ◽  
Early Onset ◽  
Atypical Antipsychotics ◽  
Population Based ◽  
Cross Sectional Study ◽  
Administrative Database ◽  
Age Group ◽  
Early Onset Schizophrenia ◽  
Cross Sectional ◽  
Assistance Programme

Abstract Background The use of atypical antipsychotics for the treatment of schizophrenia and other mental disorders in populations under 18 years of age is increasing worldwide. Little is known about treatment patterns and the influence of gender differences, which may be a predictor of clinical outcomes. The aim of this study was to investigate gender differences in the use of atypical antipsychotics in patients with early-onset schizophrenia (EOS) assisted by the public health system in Brazil. Methods We conducted a cross-sectional study of outpatients with EOS aged 10 to 17 years who received at least one provision of atypical antipsychotics (clozapine, olanzapine, risperidone, quetiapine or ziprasidone) from a large Brazilian pharmaceutical assistance programme. Data were retrieved from a nationwide administrative database from 2008 to 2017. Results Of the 49,943 patients with EOS, 63.5% were males, and the mean age was 13.6 years old. The patients were using risperidone (62.5%), olanzapine (19.6%), quetiapine (12.4%), ziprasidone (3.3%) and clozapine (2.2%). We found gender differences, especially in the 13–17 year age group (65.1% for males vs. 34.9% for females, p < 0.001), in the use of risperidone (72.1% for males vs. 27.9% for females, p < 0.001) and olanzapine (66.5% for males vs. 33.5% for females, p < 0.001). Only in the 13 to 17 years age group were the prescribed doses of olanzapine (p = 0.012) and quetiapine (p = 0.041) slightly higher for males than for females. Conclusions Our findings showed gender differences among patients diagnosed with EOS and who received atypical antipsychotics. More attention should be devoted to gender differences in research and clinical practice.

Prevalence and Associated Factors of Sarcopenia and Frailty in Parkinson’s Disease: A Cross-Sectional Study

Gerontology ◽  
2018 ◽  
Vol 65 (3) ◽  
pp. 216-228 ◽  
Author(s):  
Marina Peball ◽  
Philipp Mahlknecht ◽  
Mario Werkmann ◽  
Kathrin Marini ◽  
Franziska Murr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Population Based ◽  
Cross Sectional Study ◽  
Prevalence Rates ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tertiary Center

Background: Sarcopenia and frailty are found in up to one-third of the general elderly population. Both are associated with major adverse health outcomes such as nursing home placement, disability, decreased quality of life, and death. Data on the frequency of both syndromes in Parkinson’s disease (PD), however, are very limited. Objective: We aimed to screen for sarcopenia and frailty in PD patients and to assess potential associations of both geriatric syndromes with demographic and clinical parameters as well as quality of life. Methods: In this observational, cross-sectional study, we included 104 PD patients from a tertiary center and 330 non-PD controls from a population-based cohort aged > 65 years. All groups were screened for sarcopenia using the SARC-F score and for frailty using the Clinical Frailty Scale of the Canadian Study of Health and Aging (CSHA CFS). Prevalence rates of sarcopenia and frailty were also assessed in 18 PD patients from a population-based cohort aged > 65 years. Moreover, PD patients from the tertiary center were evaluated for motor and non-motor symptoms, quality of life, and dependency. Results: The prevalence of sarcopenia was 55.8% (95% CI: 46.2–64.9%) in PD patients from the tertiary center and 8.2% (5.7–11.7%; p < 0.001) in non-PD controls. Frailty was detected in 35.6% (27.0–45.2%) and 5.2% (3.2–8.1%; p < 0.001). Prevalence rates for sarcopenia and frailty were 33.3% (16.1–56.4%; p = 0.004) and 22.2% (8.5–45.8%; p = 0.017) in the community-based PD sample. Both sarcopenia and frailty were significantly associated with longer disease duration, higher motor impairment, higher Hoehn and Yahr stages, decreased quality of life, higher frequency of falls, a higher non-motor symptom burden, institutionalization, and higher care levels in PD patients from a tertiary center compared to not affected PD patients (all p < 0.05). Conclusions: Both frailty and sarcopenia are more common in PD patients than in the general community and are associated with a more adverse course of the disease. Future studies should look into underlying risk factors for the occurrence of sarcopenia and frailty in PD patients and into adequate management to prevent and mitigate them.

scholarly journals Testing the assumptions of an indicator of unmet need for obstetric surgery in Ghana: A cross‐sectional study of linked hospital and population‐based delivery data

Birth ◽  
2019 ◽  
Vol 46 (4) ◽  
pp. 638-647
Author(s):  
Francesca L. Cavallaro ◽  
Lisa S. Hurt ◽  
Jenny A. Cresswell ◽  
Karen Edmond ◽  
Seeba Amenga‐Etego ◽  
...  
Keyword(s):  
Unmet Need ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstetric Surgery

scholarly journals Is healthcare-seeking with gynaecological alarm symptoms influenced by personal and professional relations? A Danish population-based, cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e033471
Author(s):  
Anja Schmidt Vejlgaard ◽  
Sanne Rasmussen ◽  
Dorte Ejg Jarbøl ◽  
Kirubakaran Balasubramaniam
Keyword(s):  
Social Network ◽  
Population Based ◽  
Cross Sectional Study ◽  
Age Group ◽  
Cross Sectional ◽  
Registration System ◽  
Healthcare Seeking ◽  
Civil Registration ◽  
Personal Relation ◽  
Alarm Symptom

ObjectivesTo identify the personal and professional relations of women experiencing gynaecological alarm symptoms, to analyse if involving a personal relation is related to healthcare-seeking with gynaecological alarm symptoms, and to analyse if having an available social network is associated with involvement of this relation.DesignWeb-based, population-based, cross-sectional questionnaire survey.SettingThe general population in Denmark.ParticipantsThe study invited 100 000 individuals randomly drawn from the Danish Civil Registration System. Pregnant women and women who did not answer relevant questions about social network were excluded. A total of 5053 women who experienced at least one gynaecological alarm symptom were included in the study.Primary and secondary outcomes(1) Personal and professional relations that women experiencing gynaecological alarm symptoms involve; (2) the association between involving a personal relation and healthcare-seeking; and (3) the association between having an available social network and involvement of this relation.ResultsThe general practitioner (GP) was the most involved professional relation, while the spouse/partner was the most involved personal relation. When experiencing gynaecological alarm symptoms, more than 50% of women did not involve a professional relation and 20% did not involve a personal relation. For all four gynaecological alarm symptoms, the odds of involving the GP were higher in the oldest age group. Women were two to seven times more likely to involve their GP if they had personal relation involvement. No statistically significant association was found between having an available social network and involving the GP.ConclusionInvolving a personal relation in healthcare-seeking was associated with increased involvement of the GP, who consequently was the most involved professional relation when experiencing gynaecological alarm symptoms. Spouse/partner was the most involved personal relation. The oldest age group had the highest odds of involving the GP. No association was found between having an available social network and involving the GP.

scholarly journals Epidemiology of Childhood Hyperthyroidism in France: A Nationwide Population-Based Study

2018 ◽  
Vol 103 (8) ◽  
pp. 2980-2987 ◽  
Author(s):  
Marie Simon ◽  
Annabel Rigou ◽  
Joëlle Le Moal ◽  
Abdelkrim Zeghnoun ◽  
Alain Le Tertre ◽  
...  
Keyword(s):  
Age Groups ◽  
Poisson Model ◽  
Epidemiological Data ◽  
Epidemiological Survey ◽  
Population Based ◽  
Antithyroid Drugs ◽  
Childhood And Adolescence ◽  
Age Group ◽  
Cross Sectional ◽  
The Impact

Abstract Context Hyperthyroidism affects all age groups, but epidemiological data for children are scarce. Objective To perform a nationwide epidemiological survey of hyperthyroidism in children and adolescents. Design A cross-sectional descriptive study. Setting Identification of entries corresponding to reimbursements for antithyroid drugs in the French national insurance database. Participants All cases of childhood hyperthyroidism (6 months to 17 years of age) in 2015. Main Outcome Measures National incidence rate estimated with a nonlinear Poisson model and spatial distribution of cases. Results A total of 670 cases of childhood hyperthyroidism were identified. Twenty patients (3%) had associated autoimmune or genetic disease, with type 1 diabetes and Down syndrome the most frequent. The annual incidence for 2015 was 4.58/100,000 person-years (95% CI 3.00 to 6.99/100,000). Incidence increased with age, in both sexes. This increase accelerated after the age of 8 in girls and 10 in boys and was stronger in girls. About 10% of patients were affected before the age of 5 years (sex ratio 1.43). There was an interaction between age and sex, the effect of being female increasing with age: girls were 3.2 times more likely to be affected than boys in the 10 to 14 years age group and 5.7 times more likely to be affected in the 15 to 17 years age group. No conclusions about spatial pattern emerged. Conclusion These findings shed light on the incidence of hyperthyroidism and the impact of sex on this incidence during childhood and adolescence. The observed incidence was higher than expected from the results published for earlier studies in Northern European countries.

scholarly journals Emergency department presentations of alcohol and other substance misuse: first cross-sectional national study in Qatar

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e055181
Author(s):  
Majid Alabdulla ◽  
Shuja Reagu ◽  
Nahid M Elhassan ◽  
Dhanya Shinith ◽  
Saba T Shiekh ◽  
...  
Keyword(s):  
Substance Abuse ◽  
Substance Use ◽  
Population Based ◽  
Cross Sectional Study ◽  
National Study ◽  
Electronic Patient Records ◽  
Community Based ◽  
Cross Sectional ◽  
Starting Point ◽  
Good Starting Point

ObjectivesThis study attempts the first in a series of investigations into the misuse of alcohol and substances in Qatar. This study explores the emergency presentations of alcohol and substance abuse to all the state funded emergency departments (EDs) in the country which serve around 90% of the population over a 22-month period. Due to legal penalties for alcohol and substance use, and lack of subsidised community-based facilities, ED presentations are a good starting point to explore this burden.Design and participantsA retrospective population-based, cross-sectional study, analysing electronic patient records of all state funded EDs spanning a period of 22 months, from 1 January 2019 to 31 October 2020 was carried out. The study included all eligible individuals aged 18 or over. Primary reason/diagnosis for presentation containing any of the alcohol or substance use key words were included in the study using composite data capture forms by trained clinicians.ResultsAn overwhelming majority (95.5%) of the total 1495 cases presenting to the EDs with substance abuse were using alcohol. Only 2.1% of the cases were females. Those of Asian (non-Arab) constituted 70% of this group. Qatari citizens presented with highest proportion of substance abuse other than alcohol (23%). Overall, 2.26% of all presentations to the EDs were related to alcohol and substance abuse and this amounted to 3 ED visits per 10 000 of population per year. 56.6% of the cases presented over the weekend. Less than 1% were referred to psychiatry and no other meaningful rehabilitative interventions were offered to others.ConclusionAs Qatar moves towards establishing community-based rehabilitative resources for alcohol and substances abuse, the findings from this study will help in shaping these developments. These can include ED-based routine screening for alcohol abuse and referral to rehabilitation services without fear of legal penalties.

scholarly journals Factors Associated with Social Avoidance of Recovered COVID-19 Patients in Iran: A National Study

2021 ◽  
Author(s):  
Teamur Aghamolaei ◽  
Shokrollah Mohseni ◽  
Azin alavi ◽  
mohammed hossein chalak ◽  
Hesamaddin Kamalzadeh Takhti ◽  
...  
Keyword(s):  
Linear Regression Analysis ◽  
Education Level ◽  
National Study ◽  
Multivariate Linear Regression Analysis ◽  
Age Group ◽  
Social Avoidance ◽  
Cross Sectional ◽  
Factors Associated ◽  
Study Results ◽  
The Impact

Abstract Background: Misconceptions about the infection and health consequences of recovered Coronavirus Disease 2019 (COVID-19) patients often lead to a fear, social avoidance and discriminatory attitude. The present study explored the Factors associated with social avoidance and job-related discriminatory attitude against recovered COVID-19 patients. Methods: The present cross-sectional online study was conducted on 3,836 Iranian participants above 15 years old. The participant selected conveniently between February 19, 2021 and May 21, 2021. The data collected using a reliable and valid questionnaire that developed by research team. Univariate and multivariate linear regression analysis was used to identify the impact of factors related to social discrimination and discriminatory attitudes towards improved COVID-19 patients. Results: The results shows 56.72 and 49.06% of the population had social avoidance and job-related discriminatory attitude respectively. Furthermore, age, gender, education level, marital status, employment, presence of a recovered COVID-19 patient in family and place of residence were significant factors influencing social avoidance and job-related discriminatory attitude. As an instance, those in the 45-64 age group showed 1.1 times more social avoidance than the 20-29 age group. Also, men showed 37% less social avoidance than women. Social avoidance was significantly higher and the discriminatory attitude was higher in participants of lower education level. Besides, the job-related discriminatory attitude was 1.2 times higher in the 45-64 than the 20-29 age group. The discriminatory attitude was 16% less in men, 39%, 25% and 49% less, respectively in participants with a secondary school, diploma or university degree.Conclusions: To reduce social avoidance and job-related discriminatory attitude we suggest that the medical sector and relevant organizations provide clear and comprehensive information about improved COVID-19 patients to their families and general public through direct communication and the mass media. Base on the study results they need more focus on urban residents, women and families with a recovered member

scholarly journals Sex ratios at birth in Australia according to mother’s country of birth: A national study of all 5 614 847 reported live births 1997–2016

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0251588
Author(s):  
Kristina Edvardsson ◽  
Mary-Ann Davey ◽  
Rhonda Powell ◽  
Anna Axmon
Keyword(s):  
Total Sample ◽  
Population Based ◽  
Cross Sectional Study ◽  
High Income ◽  
Son Preference ◽  
National Study ◽  
Country Of Birth ◽  
Cross Sectional ◽  
Live Births ◽  
Promote Gender Equality

Objectives Son preference and sex selective practices have resulted in a deficit of girls in several countries, primarily across Asia. Emerging evidence indicates that son preference survives migration to Western high-income countries. The objective of this study was to assess male-to-female (M/F) ratios at birth per mother’s country of birth in Australia 1997–2016, in total and by parity, and by states/territories and over time. Methods Data for this national population-based cross-sectional study were obtained from the National Perinatal Data Collection (NPDC) and included all live births in Australia 1997–2016 (N = 5 614 847). M/F ratios with 95% Confidence Intervals were estimated. Results The M/F ratio for births to Australian-born mothers was within the expected range (1.03–1.07) regardless of parity and time period. M/F ratios were elevated above the expected range for births to mothers born in China in the total sample (M/F ratio 1.084, 95% confidence interval 1.071–1.097) and at parity 2 (1.175, 1.120–1.231), and for births to mothers born in India at parity 2 (1.146, 1.090–1.204). Parity 2 births were the most consistently male-biased across time. Across states, elevated M/F ratios were identified for both groups in New South Wales (China parity 2: 1.182, 1.108–1.260; India parity 2: 1.182, 1.088–1.285), for births to Chinese-born mothers in Victoria (total births: 1.097, 1.072–1.123; parity 1: 1.115, 1.072–1.159) and Australian Capital Territory (total births: 1.189, 1.085–1.302) and births to Indian-born mothers Western Australia (parity 2: 1.307, 1.122–1.523). Conclusions Son preference persists in some immigrant communities after migration to Australia. The consistent pattern of elevated M/F ratios across the larger states indicates that sex imbalances at birth are largely independent of restrictiveness of local abortion laws. Drivers and consequences of son preference in Western high-income settings should be explored to further promote gender equality, and to strengthen support for women who may be vulnerable to reproductive coercion.

scholarly journals Seroepidemiological Study of Novel Corona Virus (CoVID-19) in Tehran, Iran

2021 ◽  
Author(s):  
Zeinab Tabanejad ◽  
Sorena Darvish ◽  
Zeinab Borjian Boroujeni ◽  
Seyed Saeed Asadi ◽  
Morteza Mesri ◽  
...  
Keyword(s):  
False Negative ◽  
Underlying Disease ◽  
Population Based ◽  
Immunological Methods ◽  
Age Group ◽  
Igg Antibodies ◽  
Rt Pcr ◽  
Igg Antibody ◽  
Cross Sectional ◽  
Exposed Population

AbstractA novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has now spread to all countries of the world, including Iran. Although new anti-coronavirus antibodies in patients may be identified by immunological methods with sufficient sensitivity and specificity, the conclusive diagnosis of the disease is by the molecular RT-PCR process. We used a population-based seroepidemiological survey to quantify the proportion of the exposed population with SARS-CoV-2 antibodies and evaluated whether the antibodies are a marker of total or partial immunity to the proportion of the population that remains susceptible to the virus. This cross-sectional study was conducted to investigate the seroprevalence of CoVID-19 in Tehran, the capital of Iran, between April and end of October 2020. Specimens of clotted and heparinized blood (2ml) were collected from the patients. The serum and plasma were separated and stored at − 80LJ°C until use. We examined serum anti-SARS-CoV-2 IgG and IgM antibodies from 1375 in-patients admitted to our hospitals using ELISA kits. In total, 1375 participants were enrolled in this study, and SARS-CoV-2 antibodies were detected using IgM-IgG antibody assay in 291 patients. Among the seropositive patients studied, 187 were men (64.3%), and 104 were women (35.7%) (P<0.05). The mean age of the patients was 49±8.4 years; the majority (27%) were in age group 31-40 years. Also, the lowest frequency of cases was reported in the age group of 1-10 years (P <0.05). We determined the seroprevalence of SARS-CoV-2 for IgM or IgG antibodies to be 21.2%. Diabetes mellitus was the most common underlying disease among SARS-CoV-2 patients [P=0.05; Odd Ratio=1.61(0.90-2.91)]. Conventional serological assays in SARS-CoV-2 cases, such as the enzyme-linked immunoassay (ELISA) for specific IgM and IgG antibodies, have a high-throughput advantage and minimize false-negative rates that occur with the RT-PCR method. This study determined the seroprevalence of SARS-CoV-2 antibodies to be 21%. Control of diabetes among other cases factors shall play important role in management and control of COVID-19.

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