Risk factors for sanitary condemnation in broiler chickens and their relative impact: application of an original multiblock approach

2009 ◽  
Vol 138 (3) ◽  
pp. 364-375 ◽  
Author(s):  
C. LUPO ◽  
S. BOUGEARD ◽  
L. BALAINE ◽  
V. MICHEL ◽  
I. PETETIN ◽  
...  
Keyword(s):  
Risk Factors ◽  
Broiler Chickens ◽  
Relative Impact ◽  
Event Analysis ◽  
Explanatory Variables ◽  
Production Stages ◽  
Health Event ◽  
Block Organization ◽  
On Farm ◽  
Significant Factors

SUMMARYAn innovative and well-adapted statistical method, called multiblock redundancy analysis, is proposed for a complex health-event analysis to account for the thematic block organization of variables. The outcome block contained the condemnation rates of 404 broiler chicken flocks, distinguishing infectious and traumatic condemnation categories. Explanatory variables were organized in blocks related to the different production stages (farm structure and routine husbandry practices; on-farm flock history and characteristics; catching, transport and lairage conditions; slaughterhouse and inspection features). The aim was to determine risk factors for both condemnation categories, and the relative impact of the different production stages on the whole condemnation rate. Results showed that significant factors were either specific to one condemnation category or related to both categories, and each of the explanatory blocks was involved in the explanation of infectious and traumatic condemnation rates. On-farm flock information explained 40% of the overall condemnation process whereas the other explanatory blocks had similar relative impacts.

scholarly journals The Analysis of Risk Factors in the Conversion from Laparoscopic to Open Cholecystectomy

2020 ◽  
Vol 17 (20) ◽  
pp. 7571
Author(s):  
Łukasz Warchałowski ◽  
Edyta Łuszczki ◽  
Anna Bartosiewicz ◽  
Katarzyna Dereń ◽  
Marta Warchałowska ◽  
...  
Keyword(s):  
Risk Factors ◽  
Laparoscopic Cholecystectomy ◽  
Open Surgery ◽  
Open Cholecystectomy ◽  
Control Group ◽  
Inflammatory Infiltration ◽  
Peritoneal Adhesions ◽  
Explanatory Variables ◽  
Predictive Risk ◽  
Significant Factors

Laparoscopic cholecystectomy is a standard treatment for cholelithiasis. In situations where laparoscopic cholecystectomy is dangerous, a surgeon may be forced to change from laparoscopy to an open procedure. Data from the literature shows that 2 to 15% of laparoscopic cholecystectomies are converted to open surgery during surgery for various reasons. The aim of this study was to identify the risk factors for the conversion of laparoscopic cholecystectomy to open surgery. A retrospective analysis of medical records and operation protocols was performed. The study group consisted of 263 patients who were converted into open surgery during laparoscopic surgery, and 264 randomly selected patients in the control group. Conversion risk factors were assessed using logistic regression analysis that modeled the probability of a certain event as a function of independent factors. Statistically significant factors in the regression model with all explanatory variables were age, emergency treatment, acute cholecystitis, peritoneal adhesions, chronic cholecystitis, and inflammatory infiltration. The use of predictive risk assessments or nomograms can be the most helpful tool for risk stratification in a clinical scenario. With such predictive tools, clinicians can optimize care based on the known risk factors for the conversion, and patients can be better informed about the risks of their surgery.

A Strategy for Analysing Multiple Risk Factors with Application to Cervical Pain Syndrome

1989 ◽  
Vol 28 (01) ◽  
pp. 14-19 ◽  
Author(s):  
J. F. Dartigues ◽  
Ph. Peytour ◽  
E. Puymirat ◽  
P. Henry ◽  
M. Gagnon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Low Power ◽  
Head Trauma ◽  
Pain Syndrome ◽  
Psychological Status ◽  
Confounding Factors ◽  
Cervical Pain ◽  
Extreme Form ◽  
Explanatory Variables ◽  
Multiple Risk Factors

Abstract:When studying the possible effects of several factors in a given disease, two major problems arise: (1) confounding, and (2) multiplicity of tests. Frequently, in order to cope with the problem of confounding factors, models with multiple explanatory variables are used. However, the correlation structure of the variables may be such that the corresponding tests have low power: in its extreme form this situation is coined by the term “multicollinearity”. As the problem of multiplicity is still relevant in these models, the interpretation of results is, in most cases, very hazardous. We propose a strategy - based on a tree structure of the variables - which provides a guide to the interpretation and controls the risk of erroneously rejecting null hypotheses. The strategy was applied to a study of cervical pain syndrome involving 990 subjects and 17 variables. Age, sex, head trauma, posture at work and psychological status were all found to be important risk factors.

scholarly journals Effect of water features proximity on farmland prices in a landlocked country: the consequences for planning

2017 ◽  
Vol 12 (No. 1) ◽  
pp. 18-28 ◽  
Author(s):  
P. Sekáč ◽  
M. Šálek ◽  
A. Wranová ◽  
P. Kumble ◽  
P. Sklenička
Keyword(s):  
Water Resources Planning ◽  
The Czech Republic ◽  
Explanatory Variables ◽  
Land Prices ◽  
Five Factors ◽  
Real Estate Brokers ◽  
Farmland Prices ◽  
Agricultural Use ◽  
Resources Planning ◽  
Significant Factors

Conversion of farmland to non-farm uses significantly influences the spatial variability of farmland prices. We tested 12 factors of land prices that experienced real estate brokers indicated to be the most important determinants for the conversion of farmland to non-agricultural use. Five factors can be described as landscape, four as geographic, and three as climatic explanatory variables influencing farmland prices. Our results indicate that the two most powerful factors in explaining the sales price per square metre were proximity to a river and proximity to a lake. In both cases, the price of land diminished significantly with the increasing distance from the edge of water bodies, so the prices in their immediate vicinity are 3.5 to 3.7 times higher than the prices of similar lands more than 5 km from the edge of a water body. The other significant factors were population size of the nearest municipality and percentage representation of forest. The fact that the two most powerful factors indicate the distance to a river, brook, lake or pond shows how important are these freshwater features as determinants of farmland prices in a landlocked country such as the Czech Republic, where this study was performed. The consequences of this finding for water resources planning and management are discussed.

scholarly journals Leg Disorders in Broiler Chickens: Prevalence, Risk Factors and Prevention

PLoS ONE ◽  
2008 ◽  
Vol 3 (2) ◽  
pp. e1545 ◽  
Author(s):  
Toby G. Knowles ◽  
Steve C. Kestin ◽  
Susan M. Haslam ◽  
Steven N. Brown ◽  
Laura E. Green ◽  
...  
Keyword(s):  
Risk Factors ◽  
Broiler Chickens

scholarly journals Impact of On-Farm Interventions against CTX-Resistant Escherichia coli on the Contamination of Carcasses before and during an Experimental Slaughter

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 228
Author(s):  
Michaela Projahn ◽  
Jana Sachsenroeder ◽  
Guido Correia-Carreira ◽  
Evelyne Becker ◽  
Annett Martin ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Broiler Chickens ◽  
Stocking Density ◽  
Resistant Bacteria ◽  
Control Group ◽  
Cross Contamination ◽  
High Prevalence ◽  
On Farm ◽  
The Impact ◽  
Slow Growing

Cefotaxime (CTX)-resistant Enterobacteriaceae are still an ongoing challenge in human and veterinary health. High prevalence of these resistant bacteria is detected in broiler chickens and the prevention of their dissemination along the production pyramid is of major concern. The impact of certain on-farm interventions on the external bacterial contamination of broiler chickens, as well as their influence on single processing steps and (cross-) contamination, have not yet been evaluated. Therefore, we investigated breast skin swab samples of broiler chickens before and during slaughter at an experimental slaughter facility. Broiler chickens were previously challenged with CTX-resistant Escherichia coli strains in a seeder-bird model and subjected to none (control group (CG)) or four different on-farm interventions: drinking water supplementation based on organic acids (DW), slow growing breed Rowan × Ranger (RR), reduced stocking density (25 kg/sqm) and competitive exclusion with Enterobacteriales strain IHIT36098(CE). Chickens of RR, 25 kg/sqm, and CE showed significant reductions of the external contamination compared to CG. The evaluation of a visual scoring system indicated that wet and dirty broiler chickens are more likely a vehicle for the dissemination of CTX-resistant and total Enterobacteriaceae into the slaughterhouses and contribute to higher rates of (cross-) contamination during processing.

Clostridioides difficile on Ohio swine farms (2015): A comparison of swine and human environments and assessment of on‐farm risk factors

2019 ◽  
Vol 66 (7) ◽  
pp. 861-870
Author(s):  
Rory A. O’Shaughnessy ◽  
Gregory G. Habing ◽  
Wondwossen A. Gebreyes ◽  
Andrew S. Bowman ◽  
J. Scott Weese ◽  
...  
Keyword(s):  
Risk Factors ◽  
Swine Farms ◽  
Clostridioides Difficile ◽  
On Farm

scholarly journals 547. Risk Factors Associated with 30-Day Mortality in a Large Cohort of Patients who Received Remdesivir and Corticosteroids for Severe COVID-19

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S375-S376
Author(s):  
Kartik Gupta ◽  
Lea Monday ◽  
Milan Kaushik ◽  
George J Alangaden ◽  
Indira Brar
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Health System ◽  
Drug Administration ◽  
Food And Drug Administration ◽  
Antiviral Agent ◽  
Advanced Age ◽  
Event Analysis ◽  
Time To Event ◽  
Factors Associated

Abstract Background Remdesivir (RDV), an antiviral agent, is approved by Food and Drug Administration (FDA) for the treatment of patients (pts) admitted with SARS-COV-2 infection (COVID-19). Earlier RDV studies (such as ACCT-1) prior to widespread use of corticosteroids (CS), showed a 30-day mortality of 11%. Advanced age, obesity, and certain comorbidities are known risk factors for death in COVID-19, but whether these risks vary in pts treated with RDV and CS is unknown. As of March 20, 2020 CS were routinely used for the treatment of pts admitted with COVID19 in our health care system. The objective of this study was to identify risk factors associated with 30 -Day mortality in a cohort of pts admitted with COVID-19 and who received RDV and CS. Methods This retrospective cohort study evaluated pts admitted to a health system in South East Michigan with COVID-19 between March and November 2020 who received ≥1 dose RDV. Demographics, comorbidities, and characteristics including quick sequential organ failure assessment (qSOFA) score were collected and compared between patients who died versus survived. Primary outcome was 30 day mortality. Secondary outcomes were risk factors for death using logistic regression and time-to-event analysis. Results A total of 1,591 pts received RDV and were included in the study; median age 67 years, 56% male and 18% Black. RDV use increased after emergency use authorization and FDA approval (Fig 1). Death within 30 days occurred in 15.3%. Patients who died were older males with higher rates of hypertension, kidney disease, diabetes, and were more likely to have qSOFA ≥2 on arrival (Table 1). In a multivariable logistic model, advanced age, male gender, pulmonary disease, CKD, obesity, and qSOFA≥2 were independent predictors of death (Figure 2). Among these, age and qSOFA≥2 were the most important risk factors (Figure 2). Patients receiving remdesivir (red) were included in the study. Routine use of corticosteroids was adopted on all patients in our health system beginning March 20, 2020. System-wide use of remdesivir increased following Food and Drug Administration approval in fall 2020. On both logistic regression and time-to-event analysis, advanced age and qSOFA ≥ 2 had the highest predictive value for mortality. Others comorbidities were similar and comparable in importance. Conclusion The population in our Real-world study was older with more comorbidities as compared to ACCT-1, and the 30 day mortality was 15%. Despite the use of CS and RDV advanced age and qSOFA were the most important drivers of mortality. Future, therapeutic strategies need to focus on this group which is at the highest risk of dying from COVID-19 infection. Disclosures All Authors: No reported disclosures

SIGNIFICANT ASPECTS OF EPIDEMIOLOGY, RISK FACTORS AND TREATMENT OF VARICOSE VEINS

2020 ◽  
pp. 320-328
Author(s):  
O.F. SOLIEV ◽  
◽  
D.D. SULTANOV ◽  
S.P. KURBANO ◽  
N.R. KURBANOV ◽  
...  
Keyword(s):  
Risk Factors ◽  
Optical Fibers ◽  
High Efficiency ◽  
Varicose Veins ◽  
Laser Wavelength ◽  
Comprehensive Treatment ◽  
Literature Analysis ◽  
Pregnancy And Childbirth ◽  
Laser Ablation Technique ◽  
Significant Factors

The literature review focuses on the significant aspects of epidemiology, analysis of risk factors and modern principles of surgical treatment of varicose veins. Literature data show that considering pathology in recent years has a tendency to increase the frequency and the significant factors at risk of its development are the inheritance, overweight, as also pregnancy and childbirth of two or more. In recent years, new thermal catheter techniques have become more frequent in the treatment of varicose veins, which demonstrate their advantages and high efficiency. The literature analysis shows that the use of a 1470 nm laser wavelength with a radial type of optical fibers has the highest coagulating effect compared to other types of laser. The authors of the article provided detailed coverage of the endovascular laser ablation technique, showing its advantages over other methods, and its role and place in the comprehensive treatment of the varicose veins.

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