Phytic acid and phosphorus in crop seeds and fruits: a global estimate

2000 ◽  
Vol 10 (1) ◽  
pp. 11-33 ◽  
Author(s):  
John N.A. Lott1 ◽  
Irene Ockenden ◽  
Victor Raboy ◽  
Graeme D. Batten
Keyword(s):  
Phytic Acid ◽  
Fruit Production ◽  
Mineral Fertilizers ◽  
Global Estimate ◽  
Anti Cancer ◽  
Potential Benefits ◽  
Anti Oxidant ◽  
Total Crop ◽  
Cancer Agent ◽  
Seeds And Fruits

AbstractA very important mineral storage compound in seeds is phytate, a mixed cation salt of phytic acid (myo-inositol hexakis phosphoric acid). This compound is important for several reasons: (1) It is vital for seed/grain development and successful seedling growth. (2) It is often considered to be an antinutritional substance in human diets, but it may have a positivenutritional role as an anti-oxidant and an anti-cancer agent. (3) It represents a very significant amount of phosphorus being extracted from soilsand subsequently removed with the crop. (4) It plays a role in eutrophication of waterways. A key part of this review is an estimate of the annualtonnage of phosphorus and phytic acid sequestered in up to 4.1 billion metric tonnes of crop seeds and fruits globally each year. We estimate thatnearly 35 million metric tonnes of phytic acid, containing 9.9 million metric tonnes of P, is combined with about 12.5 and 3.9 million metric tonnes of K and Mg respectively, to form each year over 51 million metric tonnes of phytate. The amount of P inthis phytate is equal to nearly 65÷ of the elemental P sold world wide for use in mineral fertilizers. Dry cereal grains account for 69÷ of the total crop seed/fruit production but account for 77÷ of the total phytic acid stored each year. Low phytate mutants, that are now available for some key staple food crops such as maize and barley, offer potential benefits in such areas as the sustainability of lands used to grow crops, the mineral nutrition of humans and animals, and reduction in pollution of waterways.

scholarly journals Purification, Structural Characteristics, and Biological Activities of Exopolysaccharide Isolated From Leuconostoc mesenteroides SN-8

2021 ◽  
Vol 12 ◽  
Author(s):  
Junrui Wu ◽  
Danli Yan ◽  
Yumeng Liu ◽  
Xue Luo ◽  
Yang Li ◽  
...  
Keyword(s):  
Leuconostoc Mesenteroides ◽  
Biological Activities ◽  
Structural Characteristics ◽  
Molecular Weights ◽  
Cycle Arrest ◽  
Glycosidic Bonds ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Inhibitory Potential ◽  
Cancer Agent

In this study, a novel exopolysaccharide (EPS) was extracted from Leuconostoc mesenteroides Shen Nong’s (SN)-8 which can be obtained from Dajiang. After the purification step, EPS-8-2 was obtained with molecular weights of 1.46 × 105 Da. The structural characterization of EPS indicated that the EPS belonged to the class polysaccharide, mainly composed of glucan and also contained certain mannose residues that were found to be connected by α-1,6 glycosidic bonds. Moreover, the results demonstrated that EPS displayed a significant capacity to scavenge free radical to some extent, and this anti-oxidant potential was found to be concentration dependent. The results further revealed that EPS displayed a significant inhibitory potential on the growth of HepG2 cells by promoting apoptosis and induced cell cycle arrest in G1 and G2 phases. Overall, these results suggested that EPS can be explored as a possible anti-cancer agent.

scholarly journals POTENTIAL AND THERAPEUTIC BENEFITS OF TINOSPORA CORDIFOLIA

2021 ◽  
Vol 10 (3) ◽  
pp. 2965-2970
Author(s):  
Prashant L Pingale ◽  
Keyword(s):  
Tinospora Cordifolia ◽  
Immunomodulatory Activity ◽  
Antipyretic Activity ◽  
Therapeutic Benefits ◽  
Anti Cancer ◽  
Potential Benefits ◽  
Anti Oxidant ◽  
Large Application ◽  
Ayurvedic Treatment

Essential crude products with potential benefits are steadily achieving significance in clinical studies and research because of their quality of minimal adverse effects as associated with allopathic medications. Tinospora cordifolia usually recognized as Guduchi is known for its large application in the therapy and cure of various diseases in conventional ayurvedic treatment. Recently the classification of active constituents of Guduchi and their inherent function in disease limitation has led us to an active activity in the plant around the globe. This review comprises the genetic variety of the parts of Tinospora cordifolia and active ingredients isolated from Tinospora cordifolia and helps in treating diseases due to their potential benefits such as Anti-oxidant activity, Anti-diabetic activity, Immunomodulatory activity, Anti-cancer activity, Anti-toxic effect, Anti-hyperlipidemic Property, Analgesic, anti-inflammatory, antipyretic activity, and many others. This review aims to utilize the biochemical and significant routes induced by the aggregates separated from Tinospora cordifolia to allow different and efficient therapeutic formulations in disease elimination.

A Global Estimate of Phytic Acid and Phosphorus in Crop Grains, Seeds, and Fruits

Food Phytates ◽  
2001 ◽  
Author(s):  
John Lott ◽  
irene ockenden ◽  
victor raboy ◽  
graemed batten
Keyword(s):  
Phytic Acid ◽  
Global Estimate ◽  
Seeds And Fruits

scholarly journals A review on Tinospora cordifolia: as an Immunomodulating agent

2021 ◽  
pp. 6-14
Author(s):  
Pritika Devi
Keyword(s):  
Clinical Studies ◽  
Indian Subcontinent ◽  
Tinospora Cordifolia ◽  
Skin Disorders ◽  
Anti Cancer ◽  
The Family ◽  
Different Types ◽  
Anti Oxidant ◽  
Immunomodulating Property ◽  
Cancer Agent

Guduchi is a plant also known as Tinospora cordifolia, having heart shaped leave, an herb of the family Menispermaceae native of hot areas of the Indian subcontinent. In our classical Ayurvedic texts, it is indicated to be beneficial in treating various types of diseases like skin disorders, different types of fever, jaundice & gout. Guduchi also claimed to have various properties as an anti-oxidant, antihyperglycemic, antihyperlipidemic, hepatoprotective, cardiovascular protective, neuroprotective, osteoprotective, radioprotective, anti-anxiety, adaptogenic agent, analgesic, anti-inflammatory, antipyretic, athrombolytic agent, anti-diarrheal, anti-ulcer, antimicrobial and anti-cancer agent. Several experimental and clinical studies based on available reports, present paper is an attempt to assemble the information on immunomodulating property of Tinospora cordifolia

Stimulated Growth of Green Algae Haematococcus Pluvialis Under Different Environmental Conditions

2018 ◽  
Vol 18 (1) ◽  
pp. 53-61
Author(s):  
Arevik Minasyan
Keyword(s):  
Growth Rate ◽  
Green Algae ◽  
Haematococcus Pluvialis ◽  
Parallel Testing ◽  
Anti Cancer ◽  
Health Promoting ◽  
Sustainable Cultivation ◽  
Anti Oxidant ◽  
Culture Growth ◽  
Cancer Agent

Abstract Haematococcus pluvialis is a genus of green algae that keeps the high interest of the scientists for decades due to its capacity to synthesize astaxanthin. Among many others, astaxanthin is one of the most demanded natural anti-oxidant and the product of the future. It has the widest usage as source of nutrient rich food and health promoting compounds. Astaxanthin has got various applications in the nutraceuticals as immune system enhancer and anti-cancer agent, in the cosmetics as anti-aging component, as additive to food, as well as in the aquaculture industries. As a key requirement for the research in this field is to find out the better conditions and media to stimulate the H.pluvialis higher growth rate to reach in the field of microalgae economically sustainable cultivation and processing. The effect of WC versus BG-11 media to enhance growth rate of Haematococcus pluvialis has been examined. This study employed a parallel testing of stimulating effect of extra vitamins versus phosphorus. Combination of mentioned parameters with gentle shacking have been determined as multiple effectors that contribute to green algae cultures to grow to high density. Importantly, this study demonstrates that extra phosphorus contribute to growth rate of H.pluvilais positively, meanwhile addition of extra vitamins in combination with extra phosphorus impact both positively and negatively to promote cells division. Shacking influences the culture growth as either stimulator or repressor.

scholarly journals Enhanced cytotoxic potential of Orthosiphon stamineus extract in MCF-7 cells through suppression of nucleolin and bcl2

2017 ◽  
Vol 12 (3) ◽  
pp. 268 ◽  
Author(s):  
Renuka Saravanan ◽  
Brindha Pemaiah ◽  
Sriram Sridharan ◽  
Mahesh Narayanan ◽  
Sivakumar Ramalingam
Keyword(s):  
Cytochrome C ◽  
Cinnamic Acid ◽  
Video Clip ◽  
Orthosiphon Stamineus ◽  
Ms Analysis ◽  
Anti Cancer ◽  
Full Screen ◽  
Anti Oxidant ◽  
Cancer Agent ◽  
Mcf 7

<p>The aim of the present study was to analyze the anti-cancer effect of <em>Orthosiphon stamineus</em> leaf extract on MCF-7 cells. Ethyl acetate extract of the plant was eluted and pooled into 6 fractions based on their R<sub>f</sub> values and the fractions were tested for cytotoxicity. Fraction 3 was found effective (IC<sub>50 </sub>= 28.5 µL/mL) and was subjected to LC-MS analysis which indicated the presence of biochanin, eleutherol and cinnamic acid. Further, cytotoxic effect of the fraction was confirmed in terms of nucleolin, bcl<sub>2</sub>, bax and cytochrome c expression in MCF-7 cells through RT-PCR where a marked decrease in nucleolin, bcl<sub>2</sub> and increase in bax and cytochrome c were observed. The presence of eleutherol, a well-known anti-oxidant and anti-cancer agent, has been reported for the first time in<em> O. stamineus</em>. The anti-cancer activity of <em>O. stamineus</em> may be due to the presence of elutherol and cinnamic acid.</p><p><strong>Video Clip of Methodology</strong>:</p><p>LC-MS analysis of <em>Orthosiphon stamineus</em> extract: 7 min 33 sec   <a href="https://youtube.com/v/7Vop4epRjB0">Full Screen</a>   <a href="https://youtube.com/watch?v=7Vop4epRjB0">Alternate</a> </p>

Benzoxazinoids in human diet: an anti-cancer agent?

2019 ◽  
Author(s):  
B Bhattarai ◽  
SK Steffensen ◽  
PL Gregersen ◽  
JH Jensen ◽  
KD Sørensen ◽  
...  
Keyword(s):  
Human Diet ◽  
Anti Cancer ◽  
Cancer Agent

Role of Rasayan Churna in outbreak of Covid -19 as preventive and curative aspect

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1208-1212
Author(s):  
Amol Madhav Deshpande ◽  
Mayuri Amol Deshpande
Keyword(s):  
Recurrent Infection ◽  
Symptomatic Patient ◽  
H1n1 Influenza ◽  
Drug Of Choice ◽  
Asymptomatic Patients ◽  
Diseased Person ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Immune Booster ◽  
Respiratory Droplets

In last two decade world suffer with three epidemic diseases like SARS-CoV, H1N1 influenza, MERS –CoV and presently the world under a pandemic of Covid-19, out of these SARS-CoV, MERS –CoV and Covid-19 are form the same virus call as corona, which primary present on bats and transferred from animal to human, and then it transfer from human to human mostly by respiratory droplets or in the direct contact with the diseased person, these recurrent infection of corona virus is the burning issue in the word, so to avoid these recurrent infections good habitual behaviour with regular immune booster medicine should be taken which can be used in both normal and symptomatic patient for this Rasayan churna  is the best drug of choice as it is used for  rejuvenation therapy. From literally study from various recourses it is found that Rasayan churna have property anti-depressant, anti-xylotic, Immunomodulatory, Anti-diabetes, anti hypertensive, anti-inflammatory, Anti-toxic effects, Anti-arthritic, Anti-cancer effects, Anti-microbial effect, and Anti-oxidant which can be useful in preventive aspect of Covid -19 in all phase like normal individual, also can be used in asymptomatic patients and symptomatic patients, clinical study can be performed for the same to evaluate the result.

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