Ommoord District Residents: Prevalence and Treatment of Depression

1999 ◽  
Vol 11 (4) ◽  
pp. 385-397 ◽  
Author(s):  
F. M. Baker ◽  
Lenore J. Launer ◽  
Monique M. R. Breteler ◽  
Albert Hofman
Keyword(s):  
Psychiatric Disorders ◽  
Depressive Disorders ◽  
Psychotic Disorders ◽  
Suicide Attempts ◽  
Demographic Data ◽  
Antidepressant Medication ◽  
Cohort Effect ◽  
Lifetime Prevalence ◽  
Age Cohort ◽  
History Of

Background: Ommoord District residents of Rotterdam, The Netherlands, age 55 and older, completed a two-stage interview to assess the risk factors for chronic disease and disability. Methods: In the in-home Stage I interview (N = 7,983), demographic data and medical history were collected by a trained lay interviewer. During Stage II, a physician interview and examination were conducted at the study center. Subjects (N = 7,129) were asked about their history of psychiatric disorders and 6,596 responded. Results: The lifetime prevalence of self-reported psychiatric disorders was 5.44% for unipolar and bipolar depressive disorders combined, 0.27% for psychotic disorders, 0.08% for alcoholism, 0.05% for drug addiction, and 3.71% for other diagnoses. Residents reporting a psychiatric diagnosis of depression were more likely to be currently taking an antidepressant medication (p < .001) and an antipsychotic medication (p < .0001), to be in current outpatient treatment (p < .001), to have been hospitalized for psychiatric illness (p < .001), to have undergone electroconvulsive treatments (p < .001), and to report a history of having made suicide attempts (p < .001). Conclusion: The self-reported lifetime prevalence of affective disorders was similar to the rates found in the Stirling County Study (Canada) and the Epidemiologic Catchment Area Survey (United States). The lower prevalence rates of the other psychiatric disorders may reflect underreporting or an age cohort effect, or may be due to the nonresponse bias.

The epidemiology of non-suicidal self-injury: lifetime prevalence, sociodemographic and clinical correlates, and treatment use in a nationally representative sample of adults in England

2021 ◽  
pp. 1-9
Author(s):  
Richard T. Liu
Keyword(s):  
Psychiatric Disorders ◽  
Suicide Attempts ◽  
Clinical Importance ◽  
High Rate ◽  
Lifetime Prevalence ◽  
Medical Attention ◽  
Treatment Needs ◽  
Self Injury ◽  
Biological Parents ◽  
Nationally Representative

Abstract Background Although the clinical importance of non-suicidal self-injury (NSSI) has received increasing recognition, relatively little is known about its epidemiology. The objective of this study was to estimate the lifetime prevalence of NSSI in adults and its association with sociodemographic characteristics, psychiatric disorders, and lifetime treatment for NSSI. Methods A nationally representative face-to-face survey was conducted with 7192 adults aged ≥18 years in England. Respondents were interviewed about engagement in NSSI, psychiatric illness, suicidal thoughts and behavior, and treatment history for this behavior. Results The estimated lifetime prevalence rate of NSSI was 4.86%. Younger age, growing up without biological parents in the household, being unmarried, and impoverished backgrounds were associated with NSSI. The majority of respondents with lifetime NSSI (63.82%) had at least one current psychiatric disorder. Most psychiatric conditions were associated with greater odds of lifetime NSSI in multivariate models. NSSI was strongly associated with suicidal ideation and suicide attempts, respectively, even after accounting for psychiatric disorders and sociodemographic covariates. A substantial proportion of respondents with NSSI history (30.92%) have engaged in medically severe self-harm, as indexed by requiring medical attention for this behavior. The majority of respondents with NSSI (56.20%) had not received psychiatric care for this behavior. Conclusions NSSI is prevalent in the general population and associated with considerable psychiatric comorbidity. A high rate of unmet treatment needs is evident among those with this behavior. Those at the greatest lifetime risk for NSSI may also be particularly limited in their resources to cope with this behavior.

Insomnia Symptom Severity is Associated with Increased Suicidality and Death by Suicide in a Sample of Patients with Psychiatric Disorders

SLEEP ◽  
2021 ◽  
Author(s):  
Zach Simmons ◽  
Gary Burlingame ◽  
Juergen Korbanka ◽  
Kevin Eastman ◽  
Douglas Thomas ◽  
...  
Keyword(s):  
Psychiatric Disorders ◽  
Suicidal Behavior ◽  
Symptom Severity ◽  
Suicide Attempts ◽  
Sleep Problems ◽  
Manner Of Death ◽  
Insomnia Symptom ◽  
History Of ◽  
Depressive Personality ◽  
Insomnia Symptoms

Abstract Study Objectives Insomnia is a risk factor for suicidal behavior including attempts and death by suicide. We investigated whether insomnia symptom severity was associated with suicidality and death by suicide in patients with psychiatric disorders. Methods The sample included 180 deceased patients with psychiatric disorders seen at Weber Human Services between 2008 and 2018 who completed the Outpatient Questionnaire-45.2 (OQ) prior to death. Insomnia symptom severity was assessed using item 41 from the OQ. Manner of death was determined by death records and autopsy reports. History of suicidality was determined through electronic medical records. Cases were grouped into 4 lifetime categories: non-suicidal (n=30), suicidal ideation (n=36), suicide attempt (n=95), and death by suicide (n=19). Demographic, medical, and psychiatric features of each group were compared using linear regression. Logistic regression was used to determine whether insomnia symptom severity was associated with lifetime suicidality severity grouping, adjusting for psychiatric disorders commonly linked to suicidality. Results Lifetime suicidality was associated with sleep problems, fatigue, headaches, and psychiatric disorders (i.e., depressive, personality, and trauma-related disorders). Referenced to the non-suicidal group, greater insomnia symptom severity was significantly associated with suicide attempts and death by suicide, with odds ratios (OR) of OR=2.67, p=0.011, and OR=5.53, p=0.002, respectively, even after adjusting important psychiatric diagnoses. Conclusions Results suggest that insomnia symptom severity endorsed during a clinical visit is associated with heightened suicidality, especially suicidal behavior. The presence of insomnia symptoms in patients with psychiatric disorders may indicate risk for suicide and is a target for suicide prevention.

scholarly journals Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores

2020 ◽  
Author(s):  
Brandon J. Coombes ◽  
Matej Markota ◽  
J. John Mann ◽  
Colin Colby ◽  
Eli Stahl ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Psychiatric Disorders ◽  
Suicide Attempts ◽  
Risk Scores ◽  
Rapid Cycling ◽  
Clinical Heterogeneity ◽  
Polygenic Risk ◽  
Clinical Observations ◽  
History Of ◽  
Dsm Iv

AbstractBipolar disorder (BD) has high clinical heterogeneity, frequent psychiatric comorbidities, and elevated suicide risk. To determine genetic differences between common clinical sub-phenotypes of BD, we performed a systematic PRS analysis using multiple polygenic risk scores (PRSs) from a range of psychiatric, personality, and lifestyle traits to dissect differences in BD sub-phenotypes in two BD cohorts: the Mayo Clinic BD Biobank (N = 968) and Genetic Association Information Network (N = 1001). Participants were assessed for history of psychosis, early-onset BD, rapid cycling (defined as four or more episodes in a year), and suicide attempts using questionnaires and the Structured Clinical Interview for DSM-IV. In a combined sample of 1969 bipolar cases (45.5% male), those with psychosis had higher PRS for SCZ (OR = 1.3 per S.D.; p = 3e-5) but lower PRSs for anhedonia (OR = 0.87; p = 0.003) and BMI (OR = 0.87; p = 0.003). Rapid cycling cases had higher PRS for ADHD (OR = 1.23; p = 7e-5) and MDD (OR = 1.23; p = 4e-5) and lower BD PRS (OR = 0.8; p = 0.004). Cases with a suicide attempt had higher PRS for MDD (OR = 1.26; p = 1e-6) and anhedonia (OR = 1.22; p = 2e-5) as well as lower PRS for educational attainment (OR = 0.87; p = 0.003). The observed novel PRS associations with sub-phenotypes align with clinical observations such as rapid cycling BD patients having a greater lifetime prevalence of ADHD. Our findings confirm that genetic heterogeneity underlies the clinical heterogeneity of BD and consideration of genetic contribution to psychopathologic components of psychiatric disorders may improve genetic prediction of complex psychiatric disorders.

Euthanasia and assisted suicide of persons with psychiatric disorders: the challenge of personality disorders

2019 ◽  
Vol 50 (4) ◽  
pp. 575-582 ◽  
Author(s):  
Marie E. Nicolini ◽  
John R. Peteet ◽  
G. Kevin Donovan ◽  
Scott Y. H. Kim
Keyword(s):  
Content Analysis ◽  
Personality Disorders ◽  
Psychiatric Disorders ◽  
Assisted Suicide ◽  
Suicide Attempts ◽  
Cross Sectional ◽  
Psychiatric Comorbidities ◽  
Directed Content Analysis ◽  
Complex Patient ◽  
History Of

AbstractBackgroundEuthanasia or assisted suicide (EAS) for psychiatric disorders, legal in some countries, remains controversial. Personality disorders are common in psychiatric EAS. They often cause a sense of irremediable suffering and engender complex patient–clinician interactions, both of which could complicate EAS evaluations.MethodsWe conducted a directed-content analysis of all psychiatric EAS cases involving personality and related disorders published by the Dutch regional euthanasia review committees (N = 74, from 2011 to October 2017).ResultsMost patients were women (76%, n = 52), often with long, complex clinical histories: 62% had physical comorbidities, 97% had at least one, and 70% had two or more psychiatric comorbidities. They often had a history of suicide attempts (47%), self-harming behavior (27%), and trauma (36%). In 46%, a previous EAS request had been refused. Past psychiatric treatments varied: e.g. hospitalization and psychotherapy were not tried in 27% and 28%, respectively. In 50%, the physician managing their EAS were new to them, a third (36%) did not have a treating psychiatrist at the time of EAS request, and most physicians performing EAS were non-psychiatrists (70%) relying on cross-sectional psychiatric evaluations focusing on EAS eligibility, not treatment. Physicians evaluating such patients appear to be especially emotionally affected compared with when personality disorders are not present.ConclusionsThe EAS evaluation of persons with personality disorders may be challenging and emotionally complex for their evaluators who are often non-psychiatrists. These factors could influence the interpretation of EAS requirements of irremediability, raising issues that merit further discussion and research.

scholarly journals Adolescent suicide and suicidal behavior: a review

2021 ◽  
Vol 3 (Number 2) ◽  
pp. 38-42
Author(s):  
Mohammad Nurunnabi ◽  
Monowar Ahmad Tarafdar ◽  
Afroza Begum ◽  
Sultana Jahan ◽  
A F M Rezaul Islam
Keyword(s):  
Risk Factors ◽  
Psychiatric Disorders ◽  
Suicidal Behavior ◽  
Depressive Disorders ◽  
Adolescent Suicide ◽  
Suicide Attempts ◽  
Public Health Issue ◽  
Family Adversity ◽  
Middle Income ◽  
Effective Prevention

Suicide among adolescent has emerged as a major public health issue in many low and middle-income (LAMI) countries. Suicidal behavior including ideation and attempt are the most important predictors of completed suicide and offer critical points for intervention. This article reviews recent population and national data based studies of adolescent suicide and suicide attempters for analyzing risk factors for adolescent suicide and suicidal behavior. According to WHO estimates, 800,000 suicide deaths occurred worldwide in 2016 and it is the third leading cause of death for 15-19 year olds. The suicide rate in Bangladesh was 5.9 per 100,000 population in 2016 (4.7 for males and 7.0 for females). Approximately, 90 percent of suicide cases meet criteria for a psychiatric disorder, particularly major depression, substance abuse and prior suicide attempts are strongly related to adolescent suicides. The relationship between psychiatric disorders and adolescent suicide is now well established. Factors related to family adversity, social alienation and precipitating problems also contribute to the risk of suicide. The main target of effective prevention of adolescent suicides is to reduce suicide risk factors. Recognition and effective management and control of psychiatric disorders, e.g. depression, are essential in preventing adolescent suicides. Research on the treatment of diagnosed depressive disorders and of those with suicidal behavior is reviewed.

Impulsive-aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide

2007 ◽  
Vol 38 (3) ◽  
pp. 407-417 ◽  
Author(s):  
A. McGirr ◽  
J. Renaud ◽  
A. Bureau ◽  
M. Seguin ◽  
A. Lesage ◽  
...  
Keyword(s):  
Depressive Disorders ◽  
Psychotic Disorders ◽  
Novelty Seeking ◽  
Psychological Autopsy ◽  
Age Related ◽  
Younger Age ◽  
Cluster B Personality Disorders ◽  
Substance Abuse Disorders ◽  
History Of ◽  
Aggressive Behaviours

BackgroundIt is unclear whether the association between impulsive-aggressive behaviours and suicide exists across different ages.MethodVia psychological autopsy, we examined a total of 645 subjects aged 11–87 years who died by suicide. Proxy-based interviews were conducted using the SCID-I & SCID-II or K-SADS interviews and a series of behavioural and personality-trait assessments. Secondarily, 246 living controls were similarly assessed.ResultsHigher levels of impulsivity, lifetime history of aggression, and novelty seeking were associated with younger age of death by suicide, while increasing levels of harm avoidance were associated with increasing age of suicide. This effect was observed after accounting for age-related psychopathology (current and lifetime depressive disorders, lifetime anxiety disorders, current and lifetime substance abuse disorders, psychotic disorders and cluster B personality disorders). Age effects were not due to the characteristics of informants, and such effects were not observed among living controls. When directly controlling for major psychopathology, the interaction between age, levels of impulsivity, aggression and novelty seeking predicted suicide status while controlling for the independent contributions of age and these traits.ConclusionsHigher levels of impulsive-aggressive traits play a greater role in suicide occurring among younger individuals, with decreasing importance with increasing age.

Prevalence of and Risk Factors for Suicide Attempts Among Patients With Severe Psychiatric Disorders in Eastern Morocco

Crisis ◽  
2021 ◽  
Author(s):  
Mohammed Barrimi ◽  
Khalid Serraj ◽  
Ismail Rammouz ◽  
Rachid Alouane ◽  
Najoua Messaoudi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Suicide Attempt ◽  
Psychiatric Disorders ◽  
Suicide Attempts ◽  
Personal History ◽  
University Hospital ◽  
Number Of Patients ◽  
History Of ◽  
Risk Factors For Suicide

Abstract. Background: Suicide attempts are common in patients with severe psychiatric disorders; however, they are rarely studied in this population. Aims: To investigate the prevalence and risk factors associated with suicide attempts among patients with severe psychiatric disorders. Method: This is a cross-sectional study of patients admitted to the Mohammed VI University Hospital of Psychiatry in Oujda, Morocco. Results: A total of 250 patients with a psychiatric disorder were recruited in this study. Among these, 78 cases (31.2%) had a personal history of suicide attempts. A personal history of suicide attempt was significantly higher among women compared to men (45.5% vs. 27.2%, p = .0099). The most common method of suicide attempts was jumping from heights (31%). Patients with a personal history of suicide attempts had a significantly higher prevalence of alcohol consumption ( p = .0063), family history of psychiatric disorders ( p = .002), family history of suicide attempt ( p = .00004), and family history of suicide ( p = .018) compared to those who had never made suicide attempts. Limitations: As suicidal behavior is highly stigmatized in Morocco, the number of patients who have made a suicide attempt may be underestimated. Conclusion: Our findings justify the need to provide specialized support to psychiatric patients with risk factors for suicide attempts.

Psychiatric disorders and suicide attempts among adolescents victimized by school bullying

2017 ◽  
Vol 25 (4) ◽  
pp. 376-380 ◽  
Author(s):  
Young Rong Bang ◽  
Jae Hong Park
Keyword(s):  
Psychiatric Disorders ◽  
Suicide Ideation ◽  
Suicide Attempts ◽  
School Bullying ◽  
Bullying Victimization ◽  
School Students ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
The Face ◽  
History Of

Objective: We conducted a cross-sectional school-based study to investigate psychiatric disorders and suicide risk among adolescents victimized by bullying. Method: The study was designed in two stages. In the screening stage, 33,038 middle school students were screened for psychopathology. Next, in the face-to-face interview stage, 1196 participants were assessed for psychiatric disorders using a structured diagnostic instrument. We also collected information about the participants’ experiences of bullying and history of suicidal ideation/attempts. Results: The results indicate that adolescents with a history of bullying victimization were more likely to be diagnosed with depression and psychosis than those without such a history. Multivariate logistic regression models revealed that bullying victimization was significantly associated with suicide attempts even after adjusting for demographic characteristics, depression and psychosis. Conclusions: Bullying victimization is a risk factor for depression, psychosis, and suicide ideation and attempts. The findings warrant an early intervention and suicide prevention program for victimized students and anti-bullying policies in schools.

Factors Associated with Repeat Suicide Attempts among Adolescents

2000 ◽  
Vol 34 (3) ◽  
pp. 437-445 ◽  
Author(s):  
Jacqualine Vajda ◽  
Kate Steinbeck
Keyword(s):  
Substance Abuse ◽  
Sexual Abuse ◽  
Alcohol Abuse ◽  
Psychotic Disorders ◽  
Attempted Suicide ◽  
Suicide Attempts ◽  
Chronic Medical Conditions ◽  
Medical Conditions ◽  
Factors Associated ◽  
History Of

Objective: To determine potential risk factors associated with repeat suicide attempts among adolescents. Method: Retrospective medical record review of all patients aged 13–20 years who presented to the emergency department at an inner city tertiary hospital after attempted suicide between 1994 and 1996. Subjects were identified using the International Classification of Diseases (ICD-9) codes E950.0 to E959.9 for attempted suicide. Study variables included demographic parameters, chronic medical conditions/illnesses, psychiatric and substance abuse disorders, history of sexual abuse and previous and subsequent suicide attempts. Variables univariately associated with repetition at p < 0.25 were entered into a multiple regression analysis. Results: Eighty seven per cent of patients presented with a drug overdose. Seventy-six per cent of all subjects attempted suicide in the context of a dispute or relationship break-up. At least one psychiatric disorder was present in 76% of subjects at the index attempt. The most frequently diagnosed disorders were depression (45.5%) and drug (34%) and alcohol abuse (27%). Variables predicting repetition within 12 months were drug (OR = 3.891, p = 0.02) and alcohol abuse (OR = 3.56, p = 0.05), non-affective psychotic disorders (OR = 3.81, p = 0.04), and chronic medical conditions/illness (OR = 3.29, p = 0.03). A history of sexual abuse was almost significant (OR = 3.03, p = 0.06). Conclusions: Adolescents most likely to re-attempt suicide with 12 months present with either substance abuse, non-affective psychotic disorders, chronic medical conditions, or a history of sexual abuse. All adolescents with a possible suicide attempt should receive a comprehensive mental health and psychosocial assessment. Closer scrutiny of the role of chronic illnesses and sexual abuse in both future research and clinical management is urged. A broad based, multidisciplinary intervention approach is recommended.

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