Determining bronchial morphology for the purposes of segregating so-called heterotaxy

2015 ◽  
Vol 26 (4) ◽  
pp. 725-737 ◽  
Author(s):  
Rohit S. Loomba ◽  
Andrew N. Pelech ◽  
Parinda H. Shah ◽  
Robert H. Anderson
Keyword(s):  
Bronchial Tree ◽  
Clinical Findings ◽  
Chest Radiographs ◽  
Clinical Entity ◽  
Imaging Modalities ◽  
Clinical Imaging ◽  
Cardiac Morphology ◽  
Abdominal Organs ◽  
Left Isomerism ◽  
Routine Clinical Imaging

AbstractIntroductionHeterotaxy is a unique clinical entity in which lateralisation of the thoraco-abdominal organs is abnormal, typically with isomerism of the bronchial tree and atrial appendages. This study was carried out to determine whether routine clinical imaging such as chest radiographs, angiographic images, and CT/MRI can determine bronchial isomerism, and how sidedness of bronchial isomerism correlates with overall features anticipated in hearts with isomeric atrial appendages.Methods and resultsWe identified 73 patients with heterotaxy, in whom imaging clearly demonstrated the bronchial tree, seen at our institution since 1998. We calculated bronchial angles and lengths using all the available imaging modalities to determine the presence and sidedness of bronchial isomerism. This was then compared with the anticipated presence of isomeric atrial appendages based on the overall clinical findings, as the appendages themselves had not specifically been imaged.The ratio of bronchial lengths revealed bronchial isomerism in all patients, with bronchial angles permitting distinction of right as opposed to left isomerism. We noted discordances between the identified bronchial isomerism and the presumed arrangement of the atrial appendages in nearly 20% of the patients in our cohort.ConclusionRoutine clinical imaging with chest radiographs, angiographic imaging, and CT/MRI can determine the presence of bronchial isomerism in patients with so-called heterotaxy. Right as opposed to left isomerism can be distinguished based on bronchial angles. The finding of bronchial isomerism correlates well, but not totally, with the presumed isomerism of the atrial appendages as predicted from the identified intra-cardiac morphology.

scholarly journals Radiological findings in ancient Egyptian canopic jars: comparing three standard clinical imaging modalities (x-rays, CT and MRI)

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Patrick E. Eppenberger ◽  
Mislav Cavka ◽  
Michael E. Habicht ◽  
Francesco M. Galassi ◽  
Frank Rühli
Keyword(s):  
Imaging Modalities ◽  
X Rays ◽  
Radiological Findings ◽  
Clinical Imaging ◽  
Ancient Egyptian ◽  
Ct And Mri

scholarly journals Role of99mTc-ECD SPECT in the Management of Children with Craniosynostosis

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Mayadhar Barik ◽  
Minu Bajpai ◽  
Rashmi Ranajn Das ◽  
Arun Malhotra ◽  
Shasanka Shekhar Panda ◽  
...  
Keyword(s):  
Perfusion Defect ◽  
Cerebral Hemisphere ◽  
Clinical Findings ◽  
Regional Perfusion ◽  
Imaging Modalities ◽  
Early Surgery ◽  
Mental Performance ◽  
Perfusion Defects ◽  
The Mean

Purpose of the Report. There is a paucity of data on correlation of various imaging modalities with clinical findings in craniosynostosis. Moreover, no study has specifically reported the role ofTc99m-ECD SPECT in a large number of subjects with craniosynostosis.Materials and Methods. We prospectively analyzed a cohort of 85 patients with craniosynostosis from year 2007 to 2012. All patients underwent evaluation withTc99m-ECD SPECT and the results were correlated with radiological and surgical findings.Results.Tc99m-ECD SPECT revealed regional perfusion abnormalities in the cerebral hemisphere corresponding to the fused sutures preoperatively that disappeared postoperatively in all the cases. Corresponding to this, the mean mental performance quotient (MPQ) increased significantlyP<0.05postoperatively only in those children with absent perfusion defect postoperatively.Conclusions. Our study suggests that early surgery and release of craniosynostosis in patients with preoperative perfusion defects (absent onTc99m-ECD SPECT study) are beneficial, as theylead to improved MPQ after surgery.

High-resolution echo-planar imaging of the brain: is it suitable for routine clinical imaging?

1997 ◽  
Vol 39 (12) ◽  
pp. 833-840 ◽  
Author(s):  
C. Ozdoba ◽  
L. Remonda ◽  
O. Heid ◽  
K.-O. L�vblad ◽  
G. Schroth
Keyword(s):  
High Resolution ◽  
Echo Planar Imaging ◽  
Planar Imaging ◽  
Clinical Imaging ◽  
Routine Clinical Imaging ◽  
Echo Planar ◽  
The Brain

scholarly journals Current Progress and Perspective: Clinical Imaging of Islet Transplantation

Life ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 213
Author(s):  
Taylor Marie Richards ◽  
Aixia Sun ◽  
Hasaan Hayat ◽  
Neil Robertson ◽  
Zhaoda Zhang ◽  
...  
Keyword(s):  
Beta Cell ◽  
Islet Transplantation ◽  
Cell Mass ◽  
Beta Cell Mass ◽  
Molecular Probes ◽  
Imaging Modalities ◽  
Diabetic Patients ◽  
Clinical Imaging ◽  
Non Invasive

Islet transplantation has great potential as a cure for type 1 diabetes. At present; the lack of a clinically validated non-invasive imaging method to track islet grafts limits the success of this treatment. Some major clinical imaging modalities and various molecular probes, which have been studied for non-invasive monitoring of transplanted islets, could potentially fulfill the goal of understanding pathophysiology of the functional status and viability of the islet grafts. In this current review, we summarize the recent clinical studies of a variety of imaging modalities and molecular probes for non-invasive imaging of transplanted beta cell mass. This review also includes discussions on in vivo detection of endogenous beta cell mass using clinical imaging modalities and various molecular probes, which will be useful for longitudinally detecting the status of islet transplantation in Type 1 diabetic patients. For the conclusion and perspectives, we highlight the applications of multimodality and novel imaging methods in islet transplantation.

Evaluation of pulmonary arterial stiffness using routine clinical imaging methods

2013 ◽  
Vol 154 (49) ◽  
pp. 1931-1933 ◽  
Author(s):  
Attila Nemes ◽  
Tamás Forster
Keyword(s):  
Pulmonary Hypertension ◽  
Arterial Stiffness ◽  
Pulmonary Artery ◽  
Arterial Hypertension ◽  
Therapeutic Options ◽  
Present Review ◽  
Clinical Imaging ◽  
Imaging Methods ◽  
Routine Clinical Imaging ◽  
Pulmonary Arterial

Recently, there has been much debate about pulmonary hypertension due to modern therapeutic options available. Arterial hypertension is frequently associated with stiffening of a given artery. The aim of the present review is to present clinical imaging methods for the evaluation of the function and stiffness of the pulmonary artery. Orv. Hetil., 154(49), 1931–1933.

First 18F-Labeled Tracer Suitable for Routine Clinical Imaging of sst Receptor-Expressing Tumors Using Positron Emission Tomography

2004 ◽  
Vol 10 (11) ◽  
pp. 3593-3606 ◽  
Author(s):  
Margret Schottelius ◽  
Thorsten Poethko ◽  
Michael Herz ◽  
Jean-Claude Reubi ◽  
Horst Kessler ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Clinical Imaging ◽  
Positron Emission ◽  
Routine Clinical Imaging

Neoplastic zebras of venous thrombosis: Diagnostic challenges in vascular medicine

2014 ◽  
Vol 30 (10) ◽  
pp. 744-748 ◽  
Author(s):  
A Cornejo ◽  
A Lekah ◽  
AK Kurklinsky
Keyword(s):  
Venous Thrombosis ◽  
Correct Diagnosis ◽  
Medical Problem ◽  
Clinical Findings ◽  
Imaging Modalities ◽  
Resonance Imaging ◽  
Imaging Studies ◽  
Vascular Medicine ◽  
Ultrasound Computed Tomography ◽  
Magnetic Resonance Imaging Imaging

Venous thrombosis is a common medical problem. Imaging differentiation of neoplasms and venous clots may prove challenging. We report three cases of “mistaken identities” of venous thrombi and neoplasms on the basis of clinical findings and different imaging modalities: ultrasound, computed tomography, and magnetic resonance imaging. Imaging studies are not always reliable and consideration of clinical features, including pretest probability, is necessary for correct diagnosis. A combination of imaging modalities and biopsies is needed for correct diagnosis in some cases.

scholarly journals Coccidioidomycosis in Nonhuman Primates: Pathologic and Clinical Findings

2018 ◽  
Vol 55 (6) ◽  
pp. 905-915 ◽  
Author(s):  
Keith Koistinen ◽  
Lisa Mullaney ◽  
Todd Bell ◽  
Sherif Zaki ◽  
Aysegul Nalca ◽  
...  
Keyword(s):  
Vertebral Column ◽  
Nonhuman Primates ◽  
Case Series ◽  
Granulomatous Inflammation ◽  
Clinical Findings ◽  
Review Of The Literature ◽  
Endemic Region ◽  
Cutaneous Infections ◽  
Abdominal Organs ◽  
Disseminated Disease

Coccidioidomycosis in nonhuman primates has been sporadically reported in the literature. This study describes 22 cases of coccidioidomycosis in nonhuman primates within an endemic region, and 79 cases of coccidioidomycosis from the veterinary literature are also reviewed. The 22 cases included baboons ( n = 10), macaques ( n = 9), and chimpanzees ( n = 3). The majority died or were euthanized following episodes of dyspnea, lethargy, or neurologic and locomotion abnormalities. The lungs were most frequently involved followed by the vertebral column and abdominal organs. Microscopic examination revealed granulomatous inflammation accompanied by fungal spherules variably undergoing endosporulation. Baboons represented a large number of cases presented here and had a unique presentation with lesions in bone or thoracic organs, but none had both intrathoracic and extrathoracic lesions. Although noted in 3 cases in the literature, cutaneous infections were not observed among the 22 contemporaneous cases. Similarly, subclinical infections were only rarely observed (2 cases). This case series and review of the literature illustrates that coccidioidomycosis in nonhuman primates reflects human disease with a varied spectrum of presentations from localized lesions to disseminated disease.

scholarly journals Multimodality imaging review of complex pelvic lesions in female pelvis

2020 ◽  
Vol 93 (1116) ◽  
pp. 20200489
Author(s):  
Anuradha Chandramohan ◽  
Tameem Ahmed Bhat ◽  
Reetu John ◽  
Betty Simon
Keyword(s):  
Multimodality Imaging ◽  
Clinical Findings ◽  
Imaging Modalities ◽  
Imaging Features ◽  
Female Pelvis ◽  
Diagnostic Dilemma ◽  
Multiple Imaging ◽  
Wide Range ◽  
Risk Of Cancer ◽  
Pelvic Lesions

Complex pelvic lesions can originate from various anatomical structures in the pelvis and pose a diagnostic dilemma due to a wide range of possible diagnoses. Accurate characterisation of these lesions would often require an algorithmic approach, which incorporates clinical findings, sequential use of multiple imaging modalities and a multiparametric approach. This approach usually aims at identifying key imaging features, which aid in anatomical localisation, morphology and tissue characterisation. There have been various attempts to standardise the lexicon used for describing adnexal masses in female patients; stratify their risk of cancer and suggest appropriate next steps in the management pathway. Through this review, we extend this approach to complex pelvic masses in female pelvis in general and will focus on optimal use of different imaging modalities to arrive at definitive diagnosis or meaningful differential diagnosis. We will also discuss potential pitfalls of imaging diagnosis and common mimics.

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