scholarly journals Endorsement of self-report neurovegetative items of depression is associated with multiple sclerosis disease symptoms

2008 ◽  
Vol 14 (6) ◽  
pp. 1057-1062 ◽  
Author(s):  
JOE E. BEENEY ◽  
PETER A. ARNETT

AbstractSome researchers have suggested that general self-report depression scales may be inadequate for assessing depression among individuals with Multiple Sclerosis (MS), because many of such items represent MS disease symptoms. However, research has been mixed on this issue: whereas some studies provide support for symptom overlap, others have found opposing evidence. We investigated this issue in two different MS samples with three different strategies. We (1) examined reliable change in depression symptom categories at two time points over three years, (2) assessed the relationship between variables associated with depression and different depression symptom subscales, and (3) assessed the relationship between symptom subscales and physical disability. In each instance we found significant evidence that items meant to assess vegetative symptoms of depression may be influenced by presence of MS disease symptoms or were not associated with other core elements or central correlates of depression. (JINS, 2008, 14, 1057–1062.)

1995 ◽  
Vol 1 (3) ◽  
pp. 291-296 ◽  
Author(s):  
David L. Nyenhuis ◽  
Stephen M. Rao ◽  
John M. Zajecka ◽  
Tracy Luchetta ◽  
Linda Bernardin ◽  
...  

AbstractWe administered the Multiscale Depression Inventory (MDI) and the Beck Depression Inventory (BDI) to 84 multiple sclerosis (MS) patients, 101 patients diagnosed with major depression and 87 nonmedical, nonpsychiatric controls. The MDI consists of three separate depression scales measuring mood, vegetative, and evaluative symptoms. We found that: (a) MS patients did not significantly differ from the controls in mood symptoms, (b) the depression prevalence rate in MS patients was significantly lower when measured by the mood scale (17·7%) than by the BDI (30·5%) or MDI total score (26·6%), and (c) MS patients showed significantly less mood disturbance than a non-MS comparison group matched on BDI measured depression severity. We suggest that the inclusion of nonmood symptoms in self-report depression scales may artificially raise both prevalence rates and severity ratings of MS related depression and that the most valid measure of depression in MS is mood disturbance. (JINS, 1995, I, 291–296.)


1989 ◽  
Vol 18 (4) ◽  
pp. 325-338 ◽  
Author(s):  
Bruce R. Deforge ◽  
Jeffery Sobal

Depression is one of the most common mental health problems in the elderly, but there is little consensus about the best way to assess depression in the aged. The relationship between the CES-D and the ZUNG self-report depression scales was investigated in seventy-eight elderly people with osteoarthritis (mean age 71). The correlation between the scales was r = .69, with the CES-D classifying 15 percent of the participants as depressed, as compared to 6 percent by the ZUNG. Psychological symptoms had the strongest relationship with overall depression scores on both scales. No sex differences were found on psychological items on either scale, but females reported more somatic symptoms on the ZUNG. People over age seventy-four reported more psychological symptoms than their younger counterparts.


CNS Spectrums ◽  
2005 ◽  
Vol 10 (5) ◽  
pp. 372-382 ◽  
Author(s):  
Peter A. Arnett

AbstractBackground: Lifetime prevalence rates of cognitive dysfunction and depression in multiple sclerosis (MS) have typically been reported to be ∼50%. However, an inconsistent relationship between these two common features of MS has been reported in the literature. Because neurovegetative depression symptoms overlap with MS symptoms, it may be that literature inconsistencies can partly be explained by the fact that only those depression symptom clusters unambiguously reflective of depression are associated with cognitive dysfunction.Objective: To explore the relationship between different depression symptom clusters and a battery of tests measuring cognitive domains commonly impaired in MS and was examined at two time points 3 years apart.Methods: The Chicago Multiscale Depression Inventory was employed to measure mood, negative evaluative, and neurovegetative symptom clusters in 53 MS patients who were also administered a battery of neuropsychological tests.Results: At time point 1, Mood and Evaluative Chicago Multiscale Depression Inventory scales were significantly associated with tasks of complex speeded attention, planning, and working memory. At time point 2, the Evaluative scale was still significantly associated with these domains, in addition to spatial memory; however, all of the significant correlations with the Mood scale dropped out.Conclusion: These results show that negative evaluative depression symptoms are most consistently predictive of cognitive dysfunction in MS. It may be that negative evaluative depression symptoms use up available cognitive capacity, thus compromising performance on cognitive capacity demanding tasks in MS patients.


2012 ◽  
Vol 17 (5) ◽  
pp. 335-340 ◽  
Author(s):  
Whitney Scott ◽  
Michael Sullivan

BACKGROUND: Numerous investigations report that depressive symptoms frequently coexist with persistent pain. However, evidence suggests that symptoms of depression are not an inevitable consequence of pain. Diathesis-stress formulations suggest that psychological factors interact with the stress of pain to heighten the risk of depressive symptoms. Perceptions of injustice have recently emerged as a factor that may interact with the stress of pain to increase depressive symptoms.OBJECTIVES: The purpose of the present study was to examine whether perceived injustice moderates the relationship between pain and depressive symptoms.METHODS: A total of 107 individuals with persistent musculoskeletal pain completed self-report measures of pain severity, depressive symptoms, perceived injustice and catastrophizing.RESULTS: A hierarchical regression analysis revealed that the interaction between pain severity and perceived injustice uniquely contributed an additional 6% of the variance to the prediction of depressive symptoms, beyond the main effects of these variables. Post hoc probing indicated that pain was significantly related to depressive symptoms at high, but not low levels of perceived injustice. This finding remained statistically significant even when controlling for pain catastrophizing.CONCLUSIONS: The results suggest that perceived injustice augments the relationship between pain severity and depressive symptoms. The inclusion of techniques specifically targeting perceptions of injustice may enhance the effectiveness of interventions aimed at reducing symptoms of depression for individuals presenting with strong perceptions of injustice.


2018 ◽  
Vol 9 (2) ◽  
pp. 76
Author(s):  
Kalon R. Eways ◽  
Kymberley K. Bennett ◽  
Kadie M. Harry ◽  
Jillian M.R. Clark ◽  
Elizabeth J. Wilson

Background: Symptoms of depression and anxiety have been shown to negatively impact physical health outcomes among individuals with cardiovascular disease (CVD). Therefore, an important step in developing interventions to reduce risk for cardiac event recurrence is to identify the emotional and cognitive predictors of psychological distress. This study examined one possible cognitive predictor: perceived control (PC). Specifically, this study tested whether symptoms of depression and anxiety mediate the relationship between PC and adherence to health behavior recommendations in patients participating in a cardiac rehabilitation (CR) program.Methods: Self-report measures were administered to 146 CR patients at the beginning of CR and 12-weeks later, at the end of CR.Results: Anxiety and depressive symptoms did not mediate the relationship between PC and health behavior adherence. Rather, PC was cross-sectionally related to symptoms of psychological distress, and it predicted health behavior adherence 12-weeks later.Conclusions: Results imply that PC has long-term effects on health behavior adherence, an important outcome in CR that reduces risk for recurrence.


2016 ◽  
Vol 2 ◽  
pp. 205521731668277 ◽  
Author(s):  
Mayis Aldughmi ◽  
Jessie Huisinga ◽  
Sharon G Lynch ◽  
Catherine F Siengsukon

Background Perceived fatigue and fatigability are constructs of multiple sclerosis (MS)-related fatigue. Sleep disturbances lead to poor sleep quality, which has been found to be associated with perceived fatigue in people with MS (PwMS). However, the relationship between fatigability and sleep quality is unknown. Objective To explore the relationship between physical and cognitive fatigability with self-reported and objective measures of sleep quality in PwMS. Methods Fifty-one ambulatory PwMS participated in the study. Physical fatigability was measured by percent-change in meters walked on the six-minute walk test (6MWT) and in force exerted on a repeated maximal hand grip test. Cognitive fatigability was measured using response speed variability on the continuous performance test. Self-report sleep quality was measured using the Pittsburgh Sleep Quality Index, and objective sleep quality was measured using 1 week of actigraphy. Results Components of the Pittsburgh Sleep Quality Index and several actigraph parameters were significantly associated with physical fatigability and cognitive fatigability. However, controlling for depression eliminated the association between the sleep outcomes and cognitive fatigability and attenuated the association between the sleep outcomes and physical fatigability. Conclusion Poor sleep quality is related to fatigability in MS but depression appears to mediate these relationships.


2005 ◽  
Vol 7 (4) ◽  
pp. 137-142 ◽  
Author(s):  
Erin M. Snook ◽  
Mina C. Mojtahedi ◽  
Ellen M. Evans ◽  
Edward McAuley ◽  
Robert W. Motl

Individuals with multiple sclerosis (MS) engage in less physical activity than the general population. This level of inactivity may increase a person's risk of being overweight and obese. The relationship between physical activity and body composition is examined among 34 ambulatory adults with a definite diagnosis of MS. Participants wore pedometers and accelerometers, objective measures of physical activity, for 7 days; completed a self-report measure of physical activity; and underwent various measurements of body composition, including body mass index (BMI), waist circumference, and relative body fat by dual energy X-ray absorptiometry (DXA). Statistically significant negative correlations were found between physical activity levels and measures of body fatness, and the correlations were strong between the objective measures of physical activity and DXA measures of body composition. The correlations were moderate between the self-report measure of physical activity and less precise measures of body composition. Our findings suggest that inactivity plays an important role in body fatness among people with MS, and subjective measures of physical activity and less precise measures of body fatness, such as BMI, may underestimate the strength of the relationship between physical activity and risk for obesity in the MS population.


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