Effects of dry sow housing conditions on muscle weight and bone strength

1996 ◽  
Vol 62 (1) ◽  
pp. 105-113 ◽  
Author(s):  
J. N. Marchant ◽  
D. M. Broom
Keyword(s):  
Bone Strength ◽  
Total Body Weight ◽  
Muscle Weight ◽  
Locomotor Muscles ◽  
Lack Of Exercise ◽  
Three Point Bend Test ◽  
Point Bend ◽  
Total Body ◽  
Both Bones ◽  
Left Humerus

AbstractConfinement has been shown to affect bone strenth in poultry but this weakness has not been documented in other species housed in confinement. The objectives of this experiment were to compare muscle weight and bone strength in non-pregnant sows, of similar age and parity, housed throughout eight or nine pregnancies in two different dry sow systems: (1) individually in stalls and (2) communally in a large group. Following slaughter, the left thoracic and pelvic limbs were dissected and 14 locomotor muscles removed and c. ???lied. A proportional muscle weight was then calculated by dividing individual muscle weight (g) by total body weight (kg). Where there were significant differences, stall-housed sows had lower absolute and proportional muscle weights than group-housed sows. The left humerus and femur were also removed. The bones were broken by a three-point bend test using an Instron Universal Tester. Both bones from stall-housed sows had breaking strengths that were about two-thirds those of group-housed sows. The results indicate that confinement of sows, with a consequent lack of exercise, results in reduction of muscle weight and considerable reduction of bone strength.

The Effects of Dry Sow Housing Conditions on Bone Strength and Muscle Conformation

1994 ◽  
Vol 1994 ◽  
pp. 42-42 ◽  
Author(s):  
J.N. Marchant ◽  
D.M. Broom
Keyword(s):  
Body Weight ◽  
Bone Strength ◽  
Total Body Weight ◽  
Large White ◽  
Genetic Stock ◽  
Muscle Weight ◽  
Three Point Bend Test ◽  
Genetic And Environmental Factors ◽  
Point Bend ◽  
Total Body

Lameness is the second commonest cause of culling in breeding sows after reproductive failure and can occur as a result of physical injury, infection or inherent leg weakness. Lameness incidence may be affected by both genetic and environmental factors, and is especially prevalent in confined systems such as stalls and tethers, which restrict the amount of exercise that the sows can perform. Confinement, with a corresponding lack of exercise, has been shown to affect bone strength in poultry but this weakness has not been documented in other species housed in confinement. The objectives of this experiment were to compare bone strength and muscle conformation in sows housed in two different dry sow systems.A total of 18 non-pregnant Large White X Landrace sows of similar age, parity and genetic stock, were studied in two different dry sows systems: 1) permanent stalls (n=8) and 2) a large group with Electronic Sow Feeder system (n=10). All sows were weighed and following slaughter by pentabarbitone injection, the left thoracic and pelvic limbs were dissected and five forelimb and nine hindlimb locomotory muscles were removed and weighed. The muscles were chosen partly on the basis of perceived importance for locomotion and partly on the basis of ease of identification and removal. A proportional muscle weight was then calculated by dividing individual muscle weight (in grams) by total body weight (in kilograms). This removed any differences in muscle weight due purely to differences in total body weight between systems. The left humerus and femur were also removed, and were broken by a three-point bend test using an Instron Universal Tester.

Factors affecting posture-changing in loose-housed and confined gestating sows

1996 ◽  
Vol 63 (3) ◽  
pp. 477-485 ◽  
Author(s):  
J. N. Marchant ◽  
D. M. Broom
Keyword(s):  
Body Length ◽  
Total Body Weight ◽  
Muscle Weight ◽  
Factors Affecting ◽  
Housing Systems ◽  
Standing Up ◽  
Total Body ◽  
The Times ◽  
Lying Down

AbstractThe time taken to lie down and stand up was determined for dry sows from different housing systems and related to physical and genetic parameters. In experiment 1, the times taken to lie down by 32 sows in two dry-sow housing conditions were measured. Sows housed long-term in stalls took longer to lie down than group-housed sows (20·42 v. 9·28 s, P < 0·001). Group-housed sows took longer to lie down in the open than to lie down against a wall (11·07 v. 7·48 s, P = 0·004). The length of time taken for stall-housed sows to lie down had strongest association with body length (P = 0·033, R2 = 0·718). The length of time taken for group-housed sows to lie down in the open had strongest association with the proportional weight of the extensor carpi radialis, (P = 0·001, R2 = 0·915). In experiment 2, the times taken for 30 sows in stalls to lie down and stand up were measured and genotype differences investigated. There were no differences between genotypes in total times taken to stand up or lie down, but total times taken to stand up quickly and lie down had strongest association with body length (P = 0·032, R2 = 0·185, and P < 0·001, R2 = 0·574 respectively). The results indicate that sows housed long-term in gestation stalls experience difficulty of movement when standing up quickly and lying down. Although the chronic effects of lack of exercise and the acute effects offloor type may contribute to this difficulty, the major factor is likely to be space restriction as the times taken to lie down and stand up quickly both increase as body length, and hence dynamic space requirement, increases. Lying down in an unrestricted environment is under muscular control and the degree of control depends on the proportion of muscle weight to total body weight. The factors affecting lying down and standing up should be considered when designing dry-sow and farrowing accommodation.

Differential Effects of Dietary Fatty Acids on Body Composition and Adiposity

2020 ◽  
Vol 16 (2) ◽  
pp. 142-154 ◽  
Author(s):  
Hadi Emamat ◽  
Zahra Yari ◽  
Hossein Farhadnejad ◽  
Parvin Mirmiran
Keyword(s):  
Fatty Acids ◽  
Body Composition ◽  
Unsaturated Fatty Acids ◽  
Saturated Fatty Acids ◽  
Total Body Weight ◽  
Fat Distribution ◽  
Monounsaturated Fatty Acids ◽  
Dietary Fatty Acids ◽  
Dietary Fats ◽  
Total Body

Recent evidence has highlighted that fat accumulation, particularly abdominal fat distribution, is strongly associated with metabolic disturbance. It is also well-recognized that the metabolic responses to variations in macronutrients intake can affect body composition. Previous studies suggest that the quality of dietary fats can be considered as the main determinant of body-fat deposition, fat distribution, and body composition without altering the total body weight; however, the effects of dietary fats on body composition have controversial results. There is substantial evidence to suggest that saturated fatty acids are more obesogen than unsaturated fatty acids, and with the exception of some isomers like conjugate linoleic acid, most dietary trans fatty acids are adiposity enhancers, but there is no consensus on it yet. On the other hand, there is little evidence to indicate that higher intake of the n-3 and the n-6 polyunsaturated fatty acids can be beneficial in attenuating adiposity, and the effect of monounsaturated fatty acids on body composition is contradictory. Accordingly, the content of this review summarizes the current body of knowledge on the potential effects of the different types of dietary fatty acids on body composition and adiposity. It also refers to the putative mechanisms underlying this association and reflects on the controversy of this topic.

scholarly journals Lean body weight versus total body weight to calculate the iodinated contrast media volume in abdominal CT: a randomised controlled trial

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Moreno Zanardo ◽  
Fabio Martino Doniselli ◽  
Anastassia Esseridou ◽  
Massimiliano Agrò ◽  
Nicol Antonina Rita Panarisi ◽  
...  
Keyword(s):  
Body Weight ◽  
Contrast Media ◽  
Controlled Trial ◽  
Total Body Weight ◽  
Lean Body Weight ◽  
Iodinated Contrast Media ◽  
Abdominal Ct ◽  
Iodinated Contrast ◽  
Significant Difference ◽  
Total Body

Abstract Objectives Iodinated contrast media (ICM) could be more appropriately dosed on patient lean body weight (LBW) than on total body weight (TBW). Methods After Ethics Committee approval, trial registration NCT03384979, patients aged ≥ 18 years scheduled for multiphasic abdominal CT were randomised for ICM dose to LBW group (0.63 gI/kg of LBW) or TBW group (0.44 gI/kg of TBW). Abdominal 64-row CT was performed using 120 kVp, 100–200 mAs, rotation time 0.5 s, pitch 1, Iopamidol (370 mgI/mL), and flow rate 3 mL/s. Levene, Mann–Whitney U, and χ2 tests were used. The primary endpoint was liver contrast enhancement (LCE). Results Of 335 enrolled patients, 17 were screening failures; 44 dropped out after randomisation; 274 patients were analysed (133 LBW group, 141 TBW group). The median age of LBW group (66 years) was slightly lower than that of TBW group (70 years). Although the median ICM-injected volume was comparable between groups, its variability was larger in the former (interquartile range 27 mL versus 21 mL, p = 0.01). The same was for unenhanced liver density (IQR 10 versus 7 HU) (p = 0.02). Median LCE was 40 (35–46) HU in the LBW group and 40 (35–44) HU in the TBW group, without significant difference for median (p = 0.41) and variability (p = 0.23). Suboptimal LCE (< 40 HU) was found in 64/133 (48%) patients in the LBW group and 69/141 (49%) in the TBW group, but no examination needed repeating. Conclusions The calculation of the ICM volume to be administered for abdominal CT based on the LBW does not imply a more consistent LCE.

Studies on reproductive biology and ecology of blue swimming crab Portunus pelagicus from Chilika Lagoon, Orissa, India

2010 ◽  
Vol 91 (1) ◽  
pp. 257-264 ◽  
Author(s):  
D. Sahoo ◽  
S. Panda ◽  
B.C. Guru
Keyword(s):  
Gonadosomatic Index ◽  
Carapace Width ◽  
Food Habit ◽  
Total Body Weight ◽  
Fish Bone ◽  
Chilika Lagoon ◽  
Portunus Pelagicus ◽  
Commercially Important ◽  
Total Body ◽  
The Relationship

Portunus pelagicus a commercially important crab species found in Chilika lagoon constitutes about 20% of the total crab production. The carapace width (CW) ranges from 4.5–10.5 cm in both the sexes during the study period. The maximum abundance of male was at 6.6 to 7.5 cm CW whereas the females predominate from 6.6 to 9.5 cm CW. The relationship between carapace length (CL) and CW is linear in both sexes which indicates isometric growth. However, the relationship between CL, CW with total body weight (TW) is exponential. The food habit from gut content analysis shows that the species is highly carnivorous and the main food items include prawn carapace and appendages (27.58%), molluscan remaining (21.55%), fish bone (7.75%), seagrass (1.72%), unidentified materials (4.31%) and the mixed food (37.06%). The feeding index was found highest (80.95%) in February whereas it is lowest (60.9%) in June. The mature females are observed from May to July with a peak in July in the lagoon. The highest gonadosomatic index is found in July with an average CW of 10.5 cm. No berried females are found in the study period, which indicates that it did not spawn inside the lagoon and migrates to the sea during the rainy season.

Increases in adipose and total body weight, but not in lean body mass, associated with subcutaneous administration of Sonic hedgehog-Ig fusion protein to mice

2002 ◽  
Vol 57 (3) ◽  
pp. 107-114 ◽  
Author(s):  
Pauline L. Martin ◽  
Joan Lane ◽  
Louise Pouliot ◽  
Malcolm Gains ◽  
Rudolph Stejskal ◽  
...  
Keyword(s):  
Body Weight ◽  
Fusion Protein ◽  
Lean Body Mass ◽  
Body Mass ◽  
Sonic Hedgehog ◽  
Subcutaneous Administration ◽  
Total Body Weight ◽  
Total Body

scholarly journals Comparable Population Pharmacokinetics and Pharmacodynamic Breakpoints of Cefpirome in Cystic Fibrosis Patients and Healthy Volunteers

2011 ◽  
Vol 55 (6) ◽  
pp. 2927-2936 ◽  
Author(s):  
J. B. Bulitta ◽  
M. Kinzig ◽  
C. B. Landersdorfer ◽  
U. Holzgrabe ◽  
U. Stephan ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Healthy Volunteers ◽  
High Performance ◽  
Standard Dose ◽  
Total Body Weight ◽  
Volume Of Distribution ◽  
Nonparametric Bootstrap ◽  
Population Pk ◽  
Total Body ◽  
Similar Body

ABSTRACTCystic fibrosis (CF) patients are often reported to have higher clearances and larger volumes of distribution per kilogram of total body weight (WT) for beta-lactams than healthy volunteers. As pharmacokinetic (PK) data on cefpirome from studies of CF patients are lacking, we systematically compared its population PK and pharmacodynamic breakpoints for CF patients and healthy volunteers of similar body size. Twelve adult CF patients (median lean body mass [LBM] = 45.7 kg) and 12 healthy volunteers (LBM = 50.0 kg) received a single 10-min intravenous infusion of 2 g cefpirome. Plasma and urine concentrations were determined by high-performance liquid chromatography (HPLC). Population PK and Monte Carlo simulations were performed using NONMEM and S-ADAPT and a duration of an unbound plasma concentration above the MIC ≥ 65% of the dosing interval as a pharmacodynamic target. Unscaled clearances for CF patients were similar to those seen with healthy volunteers, and the volume of distribution was 6% lower for CF patients. Linear scaling of total clearance by WT resulted in clearance that was 20% higher (P≤ 0.001 [nonparametric bootstrap]) in CF patients. Allometric scaling by LBM explained the differences between the two subject groups with respect to average clearance and volume of distribution and reduced the unexplained between-subject variability of renal and nonrenal clearance by 10 to 14%. For the CF patients, robust (>90%) probabilities of target attainment (PTA) were achieved by the administration of a standard dose of 2 g/70 kg WT every 12 h (Q12h) given as 30-min infusions for MICs ≤ 1.5 mg/liter. As alternative dosage regimens, a 5-h infusion of 1.33 g/70 kg WT Q8h achieved robust PTAs for MICs ≤ 8 to 12 mg/liter and a continuous infusion of 4 g/day for MICs ≤ 12 mg/liter. Prolonged infusion of cefpirome is expected to be superior to short-term infusions for MICs between 2 and 12 mg/liter.

Effects of the teratogenic folic acid antagonist, 9-methyl pteroylglutamic acid, on hydroxyproline levels in fetal rat limbs

Development ◽  
1977 ◽  
Vol 41 (1) ◽  
pp. 289-294
Author(s):  
R. R. Schmidt ◽  
K. P. Chepenik ◽  
B. V. Paynton
Keyword(s):  
Body Weight ◽  
Folic Acid ◽  
Total Body Weight ◽  
Pregnant Rats ◽  
Skeletal Malformations ◽  
Fetal Rat ◽  
Pteroylglutamic Acid ◽  
Limb Malformations ◽  
Total Body ◽  
Rate Of Accumulation

Pregnant rats were subjected to either a folic-acid-deficient regimen that produces multiple congenital skeletal malformations, or a control folic-acid-supplemented regimen. Fetal limbs were extirpated on days 16 and 18 of gestation, pooled from each litter, homogenized, and aliquots set aside for hydroxyproline, protein and DNA determinations. We found that (1) the amount of protein recovered per treated limb was approximately half that of controls on both days, (2) the amount of protein recovered per treated or controlday-18 limb was twice that of a day-16 limb, (3) treated limbs constituted the same percentage of total body weight as in controls on day 16, but a smaller percentage than in controls on day 18, and (4) the concentration of hydroxyproline (μg/mg protein) was significantly less for treated limbs than for controls on day 18 of gestation. We noted also that: (1) lowest hydroxyproline concentrations were found in limbs from treated fetuses with gross limb malformations, (2) intermediate concentrations were found in limbs of treated fetuses not exhibiting gross limb malformations, and (3) highest concentrations were found in control limbs. We suggest that the treatment resulted in (1) a decreased rate of accumulation of protein in limbs prior to day 16, but not from day 16 to day 18, (2) a decreased rate of accumulation of some non-protein component(s) in treated limbs from day 16 to day 18, and (3) an altered collagen metabolism.

Revisión de la obesidad como concepto científico (Obesity review as a scientific concept)

Retos ◽  
2021 ◽  
Vol 42 ◽  
pp. 365-374
Author(s):  
Sagrario Lobato Huerta ◽  
Juan Víctor Moneda Rovira ◽  
Yaneth Martínez Tovilla ◽  
José Hugo Eloy Meléndez Aguilar
Keyword(s):  
Scientific Research ◽  
Total Body Weight ◽  
Scientific Concept ◽  
Individual Level ◽  
Adverse Health Effects ◽  
Noam Chomsky ◽  
Theoretical Perspectives ◽  
Grasa Corporal ◽  
Total Body ◽  
The Individual

  El lenguaje según Noam Chomsky, es una capacidad innata que puede emplearse para comunicar la ciencia. Analizar el término obesidad como concepto científico, permitirá su correcto abordaje epistemológico para contribuir con la investigación científica multidisciplinaria que busca reducir esta pandemia. La obesidad es una acumulación excesiva de grasa corporal, por encima de las necesidades fisiológicas y capacidad de adaptación, que puede conducir a efectos adversos para la salud, como una discapacidad. Se considera un estado en el que el tejido adiposo representa más del 20% del peso corporal total en hombres y el 25% en mujeres. Un IMC de 30 kg/m2 o más se cataloga como obesidad. Desde una perspectiva genética, la obesidad es clasificada en tres subdivisiones de acuerdo con el trastorno y número de genes involucrados: monogénica, sindrómica y poligénica. Para las ciencias sociales, involucra un problema sociocultural injertado en una predisposición a nivel individual. Desde la perspectiva evolutiva, el cuerpo humano no está desarrollado para la exposición constante a un ambiente rico en calorías y sedentario. Comprender las perspectivas teóricas actuales que conceptualizan a la obesidad, estipulada como patología en sí misma, como factor de riesgo para las demás enfermedades no transmisibles y como etiología indirecta de discapacidad, permitirá que la investigación científica pueda desarrollarse con panoramas más amplios, a través de su diseño con variables, categorías y teorías mixtas, que permitan formular hipótesis y explicaciones con un enfoque multidisciplinario, en concordancia con la etiología multifactorial de la obesidad.  Abstract. Language according to Noam Chomsky, is an innate ability that can be used to communicate science. Analyzing the term obesity as a scientific concept will allow its correct epistemological approach to contribute to multidisciplinary scientific research that seeks to reduce this pandemic. Obesity is an excessive accumulation of body fat, in excess of physiological needs and adaptability, which can lead to adverse health effects, such as disability. It is considered a state in which adipose tissue represents more than 20% of total body weight in men and 25% in women. A BMI of 30 kg / m2 or more is classified as obesity. From a genetic perspective, obesity is classified into three subdivisions according to the disorder and number of genes involved: monogenic, syndromic and polygenic. For the social sciences, it involves a sociocultural problem grafted onto a predisposition at the individual level. From an evolutionary perspective, the human body is not developed for constant exposure to a calorie-rich and sedentary environment. Understanding the current theoretical perspectives that conceptualize obesity, stipulated as a pathology in itself, as a risk factor for other non-communicable diseases and as an indirect etiology of disability, will allow scientific research to be developed with broader perspectives, through its design with mixed variables, categories and theories, which allow the formulation of hypotheses and explanations with a multidisciplinary approach, in accordance with the multifactorial etiology of obesity.

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