scholarly journals Selenium levels and hypertension: a systematic review of the literature

2013 ◽  
Vol 17 (6) ◽  
pp. 1342-1352 ◽  
Author(s):  
Dulanji Kuruppu ◽  
Hugh C Hendrie ◽  
Lili Yang ◽  
Sujuan Gao
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Glutathione Peroxidase ◽  
Conclusive Evidence ◽  
Outcome Variable ◽  
Review Of The Literature ◽  
Lower Blood ◽  
Study Population ◽  
The Relationship ◽  
Antioxidant Micronutrient

AbstractObjectiveSe is an antioxidant micronutrient and has been studied for its potential role in CVD prevention. The purpose of the present study was to conduct a systematic review of the literature on the relationship between Se and hypertension.DesignWe conducted a systematic literature search in PubMed and OVID of studies on Se levels and hypertension or blood pressure published in English up to June 2011. Articles meeting inclusion criteria were reviewed and the following information was gathered from each publication: study setting, participant demographics, exclusion criteria, intervention if applicable, medium of Se measure, mean level of Se, outcome definition, relationship between Se and the outcome variable, significance of this relationship, and covariates. In studies that also reported glutathione peroxidase levels, we extracted results on the relationship between glutathione peroxidase and hypertension.ResultsTwenty-five articles were included. Approximately half of the studies reported no significant relationship between Se and hypertension. Of the remaining studies, about half found that higher Se levels were associated with lower blood pressure and the other half found the opposite relationship. The studies varied greatly in terms of study population, study design and Se levels measured in participants.ConclusionsBased on the present systematic review, there is no conclusive evidence supporting an association between Se and hypertension. Randomized controlled trials and prospective studies with sufficient sample size in populations with different Se levels are needed to fully investigate the relationship between Se and hypertension.

scholarly journals 3157 Relationship between abnormal nocturnal blood pressure patterns and end-organ damage following heart transplantation.

2019 ◽  
Vol 3 (s1) ◽  
pp. 52-52
Author(s):  
Kris Oreschak ◽  
Eugene E. Wolfel ◽  
Amrut V. Ambardekar ◽  
Christina L. Aquilante
Keyword(s):  
Blood Pressure ◽  
Heart Transplant ◽  
Organ Damage ◽  
Left Ventricular ◽  
High Risk Population ◽  
Study Cohort ◽  
End Organ Damage ◽  
Study Population ◽  
Blood Pressure Patterns ◽  
The Relationship

OBJECTIVES/SPECIFIC AIMS: Heart transplant (HTx) recipients are more likely to exhibit abnormal circadian blood pressure (BP) patterns (e.g., lack of nocturnal dip in BP) compared with the general population. Our goal was to assess the relationship between abnormal circadian BP patterns and end-organ damage in HTx recipients. METHODS/STUDY POPULATION: The retrospective study included 30 patients who were ≥ 6 months post-heart transplant and had 24-hour ambulatory BP data collected during a parent study. Nocturnal BP decline was categorized as: ≥10% decline, dipper; <10% decline, non-dipper. The primary end-organ damage outcomes we plan to analyze are left ventricular hypertrophy (LVH), chronic kidney disease (CKD), and proteinuria. The association between nocturnal BP decline and the primary outcomes will be analyzed using logistic regression. RESULTS/ANTICIPATED RESULTS: The study cohort consists of 83% men and 83% Caucasians (mean age=57±14 years; mean time post-transplant =9.0±6.6 years). Systolic and diastolic non-dippers represent 53.3% and 40% of the cohort, respectively. Data are currently being analyzed for the association between nocturnal BP dipping status and LVH, CKD, and proteinuria. These findings will be presented at the conference. DISCUSSION/SIGNIFICANCE OF IMPACT: An understanding of factors, such as abnormal circadian BP patterns, that contribute to the development of end-organ damage following HTx may provide opportunities to improve BP management and prevent adverse complications in this high-risk population.

scholarly journals Association between Traffic Related Air Pollution and the Development of Asthma Phenotypes in Children: A Systematic Review

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Nelson Lau ◽  
Alex Norman ◽  
Mary Jane Smith ◽  
Atanu Sarkar ◽  
Zhiwei Gao
Keyword(s):  
Systematic Review ◽  
Air Pollution ◽  
Childhood Asthma ◽  
Literature Search ◽  
Late Onset ◽  
Meta Analysis ◽  
Persistent Asthma ◽  
Review Of The Literature ◽  
Asthma Phenotypes ◽  
The Relationship

Introduction. Traffic related air pollution (TRAP) has long been associated with the onset of childhood asthma. The relationship between TRAP exposure and the development of childhood asthma phenotypes is less understood. To better understand this relationship, we performed a systematic review of the literature studying childhood TRAP exposure and the development of childhood asthma and wheezing phenotypes (transient, persistent, and late-onset asthma/wheezing phenotypes). Methods. A literature search was performed in PubMed, Embase, and Scopus databases for current literature, returning 1706 unique articles. After screening and selection, 7 articles were included in the final review. Due to the low number of articles, no meta-analysis was performed. Results. TRAP exposure appears to be associated with both transient and persistent asthma/wheezing phenotypes. However, there was little evidence to suggest a relationship between TRAP exposure and late-onset asthma/wheezing. The differing results may be in part due to the heterogeneity in study methods and asthma/wheezing phenotype definitions, in addition to other factors such as genetics. Conclusion. TRAP exposure may be associated with transient and persistent asthma/wheezing phenotypes in children. The low number of studies and differing results suggest that further studies are warranted.

P3-039: The relationship between blood pressure and incident Alzheimer's disease: A systematic review and meta-analysis

2010 ◽  
Vol 6 ◽  
pp. S460-S460
Author(s):  
Melinda C. Power ◽  
Jennifer Weuve ◽  
Joshua Gagne ◽  
Matthew B. McQueen ◽  
Deborah Blacker
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Blood Pressure ◽  
Alzheimer's Disease ◽  
Meta Analysis ◽  
The Relationship

scholarly journals Is birth weight associated with blood pressure among African children and adolescents? A systematic review

2018 ◽  
Vol 9 (3) ◽  
pp. 270-280 ◽  
Author(s):  
S. A. Lule ◽  
A. M. Elliott ◽  
L. Smeeth ◽  
E. L. Webb
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Birth Weight ◽  
Children And Adolescents ◽  
Low Income ◽  
Later Life ◽  
Low Income Countries ◽  
Inverse Association ◽  
African Children ◽  
The Relationship

There is substantial evidence of an inverse association between birth weight and later blood pressure (BP) in populations from high-income countries, but whether this applies in low-income countries, where causes of low birth weight are different, is not certain. Objective: We conducted a review of the evidence on the relationship between birth weight and BP among African children and adolescents. Medline, EMBASE, Global Health and Web of Science databases were searched for publications to October 2016. Papers reporting the relationship between birth weight and BP among African children and adolescents were assessed. Bibliographies were searched for further relevant publications. Selected papers were summarized following the preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines. In total, 16 papers from 13 studies conducted in nine African countries (Nigeria, Republic of Seychelles, Gambia, Democratic Republic of Congo, Cameroon, South Africa, Algeria, Zimbabwe and Angola) were reviewed. Eight studies were cohorts, while five were cross-sectional. The relationship between birth weight and later BP varied with age of the participants. Studies in neonates showed a consistently positive association, while predominantly inverse associations were seen among children, and studies in adolescents were inconsistent. Based on the limited number of studies identified, the relationship between birth weight and later BP may vary with age in African children and adolescents. Not all studies adequately controlled for confounding, notably gender or age. Whether the inverse relationship between birth weight and BP in later life observed in Western settings is also seen in Africa remains unclear.

The Relationship between Religious Activities and Blood Pressure in Older Adults

1998 ◽  
Vol 28 (2) ◽  
pp. 189-213 ◽  
Author(s):  
Harold G. Koenig ◽  
Linda K. George ◽  
Judith C. Hays ◽  
David B. Larson ◽  
Harvey J. Cohen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
High Blood Pressure ◽  
Religious Activity ◽  
Religious Activities ◽  
The Bible ◽  
Lower Blood ◽  
Religious Services ◽  
Blood Pressures ◽  
The Relationship

Objective: To examine the relationship between religious activities and blood pressure in community-dwelling older adults. Method: Blood pressure and religious activities were assessed in a probability sample of 3,963 persons age sixty-five years or older participating in the Duke EPESE survey. Participants were asked if their doctor had ever informed them that they had high blood pressure and if they were currently taking medication for high blood pressure. After the interview, systolic and diastolic blood pressures were measured following a standardized protocol. Data were available for three waves of the survey (1986, 1989–90, and 1993–94). Analyses were stratified by age (65–74 vs. over 75) and by race (Whites vs. Blacks) and were controlled for age, race, gender, education, physical functioning, body mass index, and, in longitudinal analyses, blood pressure from the previous wave. Results: Cross-sectional analyses revealed small (1–4 mm Hg) but consistent differences in measured systolic and diastolic blood pressures between frequent (once/wk) and infrequent (< once/wk) religious service attenders. Lower blood pressures were also observed among those who frequently prayed or studied the Bible (daily or more often). Blood pressure differences were particularly notable in Black and younger elderly, in whom religious activity at one wave predicted blood pressures three years later. Among participants who both attended religious services and prayed or studied the Bible frequently, the likelihood of having a diastolic blood pressure of 90 mm Hg or higher was 40 percent lower than found in participants who attended religious services infrequently and prayed or studied the Bible infrequently (OR 0.60, 95% CI, 0.48–0.75, p < .0001). Among participants told they had high blood pressure, religiously active persons were more likely to be taking their blood pressure medication; this could not, however, explain the differences in blood pressure observed. While most religious activity was associated with lower blood pressure, those who frequently watched religious TV or listened to religious radio actually had higher blood pressures. Conclusions: Religiously active older adults tend to have lower blood pressures than those who are less active. This applies to attendance at religious services and private religious activities, but not to religious media. Physiological mechanisms are discussed.

scholarly journals SERUM LEPTIN LEVENS AND HEPATOCELLULAR CARCINOMA: REVIEW ARTICLE

2016 ◽  
Vol 29 (4) ◽  
pp. 276-278 ◽  
Author(s):  
Luiza Vitelo ANDRIGHETTO ◽  
◽  
Aline Kirjner POZIOMYCK ◽  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Adipose Tissue ◽  
Key Words ◽  
Malignant Tumors ◽  
Review Article ◽  
Review Of The Literature ◽  
Serum Leptin ◽  
The World ◽  
The Relationship

ABSTRACT Introduction: Hepatocellular carcinoma is one of the most frequent types of malignant tumors in the world. There is growing evidence of the relationship between it development and obesity. The mechanism that links obesity to cancer is still not fully understood; however, it is essential to the understanding the adipose tissue in metabolic changes related to obesity and hepatocellular carcinoma. Objective: To review the influence of serum leptin levels in patients with hepatocelular carcinoma. Method: Systematic review of the literature based on the methodology of the Cochrane Institute. The search for articles was in the database: Science Direct, Scielo, Medline, Lilacs e Pubmed. The key words used were hepatocellular carcinoma, leptin, adipokine. Results: After evaluation of individual studies, were selected seven studies. The results previously studied are still inconsistent and contradictory, and leptin can be effectively involved in the occurrence and development of hepatocellular carcinoma. Conclusion: Therefore, it is necessary to develop prospective, well-designed and conducted focusing on the role and specific mechanisms of this hormone in patients with hepatocellular carcinoma, so that new correlations can be properly supported.

scholarly journals Relationship Between the Aldosterone-to-Renin Ratio and Blood Pressure in Young Adults: A Longitudinal Study

Hypertension ◽  
2021 ◽  
Author(s):  
Jun Yang ◽  
Stella May Gwini ◽  
Lawrence J. Beilin ◽  
Markus Schlaich ◽  
Michael Stowasser ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Young Adults ◽  
Population Based ◽  
Continuous Variable ◽  
Sexually Dimorphic ◽  
Plasma Aldosterone Concentration ◽  
Specific Interpretation ◽  
Study Population ◽  
Aldosterone To Renin Ratio ◽  
The Relationship

Hypertension tracks throughout childhood into adulthood. Elevated aldosterone in the setting of low renin predicts incident hypertension in normotensive adults, but the relationship is unclear in adolescents and young adults. To explore this relationship, we analyzed data from the offsprings (Gen2) of women enrolled during pregnancy into the Raine Study (population-based birth cohort), who had blood pressure (BP) measurements and blood samples at age 17 years (N=871) and age 27 years (N=758). At 17 years, females had similar median aldosterone levels (349 versus 346 pmol/L) but significantly lower direct renin concentration (20.6 versus 25.7 mU/L) and thus a higher aldosterone-to-renin ratio (ARR; 18.3 versus 13.5) compared with males. However, females had lower systolic BP (109 versus 118 mm Hg) versus males. A significant association between ARR and systolic BP was detected in 17 years males when adjusted for alcohol consumption, physical activity, and body mass index. This was true whether the ARR was expressed as a continuous variable (β-coefficient 0.1, P =0.009) or categorical variable (highest versus lowest quartile, β-coefficient 3.15, P =0.003). No such correlation was observed in females at 17 years. However, the ARR at 17 years was significantly associated with both systolic (β-coefficient 0.15, P =0.009) and diastolic BP (β-coefficient 0.14, P =0.003) at 27 years among females, but not males. The sexually dimorphic relationship between the ARR and BP in 17 and 27 years participants suggests that the ARR, calculated from the plasma aldosterone concentration and direct renin concentration, could be a useful tool for BP prediction and assessment in young people, but require sex-specific interpretation.

Interpersonal Autonomic Physiology: A Systematic Review of the Literature

2016 ◽  
Vol 21 (2) ◽  
pp. 99-141 ◽  
Author(s):  
Richard V. Palumbo ◽  
Marisa E. Marraccini ◽  
Lisa L. Weyandt ◽  
Oliver Wilder-Smith ◽  
Heather A. McGee ◽  
...  
Keyword(s):  
Systematic Review ◽  
Scientific Literature ◽  
Physiological Activity ◽  
Social Processes ◽  
Review Of The Literature ◽  
Physiological Synchrony ◽  
Statistical Issues ◽  
Autonomic Physiology ◽  
Continuous Measures ◽  
The Relationship

Interpersonal autonomic physiology is defined as the relationship between people’s physiological dynamics, as indexed by continuous measures of the autonomic nervous system. Findings from this field of study indicate that physiological activity between two or more people can become associated or interdependent, often referred to as physiological synchrony. Physiological synchrony has been found in both new and established relationships across a range of contexts, and it correlates with a number of psychosocial constructs. Given these findings, interpersonal physiological interactions are theorized to be ubiquitous social processes that co-occur with observable behavior. However, this scientific literature is fragmented, making it difficult to evaluate consistency across reports. In an effort to facilitate more standardized scholarly approaches, this systematic review provides a description of existing work in the area and highlights theoretical, methodological, and statistical issues to be addressed in future interpersonal autonomic physiology research.

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