Infertility, zinc and other metals

2010 ◽  
Vol 323 ◽  
pp. 1-4
Keyword(s):  
Heavy Metals ◽  
Essential Metals ◽  
Toxic Heavy Metals ◽  
Mineral Status ◽  
Lead And Cadmium ◽  
Human Fertility ◽  
Zinc Supplements

In a nutshellPhysiological but not excessive levels of zinc, copper and other essential metals are required for human fertility, and may also help protect against accumulation of reproductively toxic heavy metals, e.g. lead and cadmium.There is limited RCT evidence for zinc supplements in treating infertility, and very little for other essential metals. Nevertheless, clinicians treating infertility should pay attention to the patient's mineral status.

Metal-induced oxidative stress level in patients with fibromyalgia syndrome and its contribution to the severity of the disease: A correlational study

2020 ◽  
pp. 1-8
Author(s):  
Varsha Shukla ◽  
Siddharth Kumar Das ◽  
Abbas Ali Mahdi ◽  
Shweta Agarwal ◽  
Ragini Alok ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heavy Metals ◽  
Fibromyalgia Syndrome ◽  
Positive Association ◽  
Protein Carbonyl ◽  
Essential Metals ◽  
Toxic Heavy Metals ◽  
Essential Trace Elements ◽  
Rheumatological Disease ◽  
Severity Of The Disease

BACKGROUND: Fibromyalgia syndrome (FMS) is an extra-articular rheumatological disease characterised by widespread chronic musculoskeletal pain. Metal-induced oxidative stress contributes to the severity of FMS. AIMS: First, this study evaluated the association between plasma levels of toxic heavy metals and essential metals with oxidative stress (OS) markers. Second, the OS markers and metal contents were correlated with the disease severity by assessing the Fibromyalgia Impact Questioner Revised (FIQR) and tender points (TP). METHOD: A total of 105 FMS patients and 105 healthy controls of similar age and sex were recruited. OS parameter such as lipid peroxidation (LPO), protein carbonyl group (PCG), nitric oxide (NO) and essential metals such as zinc (Zn), magnesium (Mg), manganese (Mn), copper (Cu) and toxic heavy metals such as aluminium (Al), arsenic (As), lead (Pb) were estimated. RESULTS: Levels of LPO, PCG, NO (p< 0.001) and Cu, Mn, and Al (p< 0.001), were significantly higher, and Mg (p< 0.001) and Zn (p< 0.001) were significantly lower in patients compared to controls. A positive association was observed between OS parameters, FIQR and TP with Cu, Al and Mn. A significant negative association was observed between Zn and Mg with FIQR, TP and OS parameters. CONCLUSION: Heavy metals such as Al induce OS parameters and decrease the levels of essential trace elements such as Mg and Zn, which may be responsible for the severity of FMS.

scholarly journals Paper-based electroanalytical devices for stripping analysis of lead and cadmium in children's shoes

RSC Advances ◽  
2020 ◽  
Vol 10 (68) ◽  
pp. 41482-41487
Author(s):  
Chen-Chen Zhu ◽  
Ning Bao ◽  
Xiao-Lei Huo
Keyword(s):  
Heavy Metals ◽  
Toxic Heavy Metals ◽  
Stripping Analysis ◽  
Lead And Cadmium ◽  
Potential Sources

Children's shoes are potential sources of toxic heavy metals, especially for younger children.

scholarly journals Pregnant Inuit Women’s Exposure to Metals and Association with Fetal Growth Outcomes: ACCEPT 2010–2015

2019 ◽  
Vol 16 (7) ◽  
pp. 1171 ◽  
Author(s):  
◽  
Eva Bonefeld-Jørgensen ◽  
Keyword(s):  
Heavy Metals ◽  
Birth Outcomes ◽  
Environmental Contaminants ◽  
Population Characteristics ◽  
The Arctic ◽  
Essential Metals ◽  
Toxic Heavy Metals ◽  
Cross Sectional ◽  
Normal Ranges ◽  
Increased Risk

Environmental contaminants such as heavy metals are transported to the Arctic regions via atmospheric and ocean currents and enter the Arctic food web. Exposure is an important risk factor for health and can lead to increased risk of a variety of diseases. This study investigated the association between pregnant women’s levels of heavy and essential metals and the birth outcomes of the newborn child. This cross-sectional study is part of the ACCEPT birth cohort (Adaption to Climate Change, Environmental Pollution, and dietary Transition) and included 509 pregnant Inuit women ≥18 years of age. Data were collected in five Greenlandic regions during 2010–2015. Population characteristics and birth outcomes were obtained from medical records and midwives, respectively, and blood samples were analyzed for 13 metals. Statistical analysis included one-way ANOVA, Spearman’s rho, and multiple linear and logistic regression analyses. The proportion of current smokers was 35.8%. The levels of cadmium, chromium, and nickel were higher compared to reported normal ranges. Significant regional differences were observed for several metals, smoking, and parity. Cadmium and copper were significantly inversely related to birth outcomes. Heavy metals in maternal blood can adversely influence fetal development and growth in a dose–response relationship. Diet and lifestyle factors are important sources of toxic heavy metals and deviant levels of essential metals. The high frequency of smokers in early pregnancy is of concern, and prenatal exposure to heavy metals and other environmental contaminants in the Greenlandic Inuit needs further research.

scholarly journals Surface Modification of the Biowaste for Purification of Wastewater Contaminated with Toxic Heavy Metals—Lead and Cadmium

2013 ◽  
Vol 03 (03) ◽  
pp. 178-184 ◽  
Author(s):  
Bindra Shrestha ◽  
Jagjit Kour ◽  
Puspa Lal Homagai ◽  
Megh Raj Pokhrel ◽  
Kedar Nath Ghimire
Keyword(s):  
Heavy Metals ◽  
Surface Modification ◽  
Toxic Heavy Metals ◽  
Lead And Cadmium

scholarly journals Simultaneous analysis of metals in various types of medicinl herbs commonly used to produce functional foods by ICP-MS

2020 ◽  
Vol 3 (1) ◽  
pp. 29-37
Author(s):  
Chien Dinh Viet ◽  
Ha Le Van ◽  
Hieu Pham Cong ◽  
Chau Nguyen Minh ◽  
Minh Hien Lu Thi ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Functional Foods ◽  
Limit Of Detection ◽  
Medicinal Herbs ◽  
Simultaneous Analysis ◽  
Toxic Heavy Metals ◽  
Lead And Cadmium ◽  
Performance Requirements ◽  
Icp Ms ◽  
Limit Of Quantitation

ICP-MS method was optimized for the simultaneous analysis of 16 metals (Pb, Cd, As, Hg, Sn, Sb, Co, Ni, Cr, Mn, Mo, Se, Cu, Fe, Zn , Al) in types of medicinal herbs commonly used to produce functional foods. The conditions of samples digestion in a closed system using a microwave and an opened system in Kjeldahl method have been studied in order to flexibly apply different methods of sample preparation in practice. The method was validated with parameters such as calibration curve, limit of detection, limit of quantitation, repeatability RSDr % (0.98 - 19.7%), reproducibility RSDR% (2.72 - 23.5%)&nbsp;and recovery R% (80.3 -109%) meeting the AOAC performance requirements. The method was applied to determine heavy metals in 40 samples of medicinal herbs of apart from the risk of pollution with some toxic heavy metals such as lead and cadmium in medicinal herbs.

Isolation of Burkholderia cepacia JB12 from lead- and cadmium-contaminated soil and its potential in promoting phytoremediation with tall fescue and red clover

2013 ◽  
Vol 59 (7) ◽  
pp. 449-455 ◽  
Author(s):  
Zhong Min Jin ◽  
Wei Sha ◽  
Yan Fu Zhang ◽  
Jing Zhao ◽  
Hongyang Ji
Keyword(s):  
Heavy Metals ◽  
Tall Fescue ◽  
Contaminated Soil ◽  
Burkholderia Cepacia ◽  
Red Clover ◽  
Toxic Heavy Metals ◽  
Cadmium Resistance ◽  
Lead And Cadmium ◽  
Net Uptake ◽  
Resistant Bacterial Strain

Phytoremediation combined with suitable microorganisms and biodegradable chelating agents can be a means of reclaiming lands contaminated by toxic heavy metals. We investigated the ability of a lead- and cadmium-resistant bacterial strain (JB12) and the biodegradable chelator ethylenediamine-N,N′-disuccinic acid (EDDS) to improve absorption of these metals from soil by tall fescue and red clover. Strain JB12 was isolated from contaminated soil samples, analysed for lead and cadmium resistance, and identified as Burkholderia cepacia. Tall fescue and red clover were grown in pots to which we added JB12, (S,S)-EDDS, combined JB12 and EDDS, or water only. Compared with untreated plants, the biomass of plants treated with JB12 was significantly increased. Concentrations of lead and cadmium in JB12-treated plants increased significantly, with few exceptions. Plants treated with EDDS responded variably, but in those treated with combined EDDS and JB12, heavy metal concentrations increased significantly in tall fescue and in the aboveground parts of red clover. We conclude that JB12 is resistant to lead and cadmium. Its application to the soil improved the net uptake of these heavy metals by experimental plants. The potential for viable phytoremediation of lead- and cadmium-polluted soils with tall fescue and red clover combined with JB12 was further enhanced by the addition of EDDS.

Content of Toxic Heavy Metals (Mercury, Lead, and Cadmium) in Canned Variegated Scallops (Chlamys varia)

2007 ◽  
Vol 70 (12) ◽  
pp. 2911-2915 ◽  
Author(s):  
A. J. GUTIÉRREZ ◽  
D. GONZÁLEZ-WELLER ◽  
T. GONZÁLEZ ◽  
A. BURGOS ◽  
G. LOZANO ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Canary Islands ◽  
Human Consumption ◽  
Santa Cruz ◽  
Toxic Heavy Metals ◽  
Lead And Cadmium ◽  
Shopping Area ◽  
Commission Regulation ◽  
Wet Weight ◽  
Maximum Limit

The concentrations of three toxic heavy metals, mercury (Hg), lead (Pb), and cadmium (Cd), were determined in preserved variegated scallops (Chlamys varia, Bivalvia, Mollusca), which are often consumed in Tenerife (Canary Islands, Spain). A total of 300 samples of seven commercial brands (A, B, D, H, J, L, and M) and one processed product (“scallop sauce”) were analyzed. Samples were collected weekly in a major shopping area in Santa Cruz de Tenerife during a 12-month period. The concentrations of lead and mercury were far below the maximum limit permitted for human consumption by the European Communities Commission regulation (EC) 466/2001 (1 and 0.5 mg kg−1 wet weight for Pb and Hg, respectively). Concentrations of cadmium were close to the maximum limit permitted by regulation (EC) 466/2001 (1 mg kg−1 wet weight).

scholarly journals A Food-Safety Risk Assessment of Mercury, Lead and Cadmium in Fish Recreationally Caught from Three Lakes in Poland

Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3507
Author(s):  
Agnieszka Chałabis-Mazurek ◽  
Jacek Rechulicz ◽  
Renata Pyz-Łukasik
Keyword(s):  
Heavy Metals ◽  
Food Safety ◽  
Muscle Tissue ◽  
Fish Species ◽  
Safety Assessment ◽  
Anthropogenic Activities ◽  
Fish Muscle ◽  
Predatory Fish ◽  
Toxic Heavy Metals ◽  
Lead And Cadmium

Heavy metals are introduced into water due to anthropogenic activities and can significantly affect an entire ecosystem. Due to their close integration with the water environment, fish are a sensitive indicator of contamination. In addition, fish is an important element in human diets, therefore, monitoring the concentrations of metallic contaminants in their meat is particularly important for food safety. This study aimed to assess the pollution of water ecosystems with selected toxic heavy metals in lakes Dratów, Czarne Sosnowickie, and Syczyńskie. The concentration of Pb, Cd, and Hg in water, sediment, and freshwater fish muscle tissue was determined, and a food safety assessment was performed. The analysis of water and sediments showed that the sediments were characterised by a significantly higher concentration of heavy metals. Presumably, this ecosystem element plays an important role in the uptake of heavy metal contaminants by fish whose levels were higher in planktonophagous and benthophagous fish species as compared to predatory fish. The food safety assessment showed that amounts of heavy metals in the muscle tissue posed no threat to the health of consumers ingesting that fish species, neither individually (THQ) nor collectively (TTHQ).

Polymorphism of p-450 cytochrome detoxication genes in adolescents depending on the degree of contamination of the organism by heavy metals

2020 ◽  
Vol 99 (5) ◽  
pp. 478-482
Author(s):  
N. P. Setko ◽  
A. G. Setko ◽  
Ekaterina V. Bulycheva ◽  
A. V. Tyurin ◽  
E. Yu. Kalinina
Keyword(s):  
Heavy Metals ◽  
Environmental Factors ◽  
Heavy Metal Contamination ◽  
Atomic Absorption Spectrophotometry ◽  
The Body ◽  
Lead And Cadmium ◽  
Cyp2b6 Gene ◽  
Cytochrome P 450 ◽  
Gene Cyp1a1 ◽  
Group 1

Introduction. Changes in the body of children and adolescents aimed at adapting to environmental factors are determined by genetic polymorphism in xenobiotic biotransformation genes, determining the degree of susceptibility of the child’s body to pollutants, which is the basis of modern personalized preventive medicine when managing risks to the health of the child population under the influence of environmental factors. Material and methods. Trace elements, including heavy metals, lead and cadmium, were determined in the hair of 256 practically healthy teenagers by atomic absorption spectrophotometry. Depending on the level of content of the latter, two groups of adolescents were formed to determine six genes of the cytochrome P-450 family. Group 1 consisted of adolescents whose cadmium lead content exceeded the average Russian indices. The second group included adolescents whose heavy metals were above the level of average Russian standards. Results. Studies have shown that in adolescents of the 1st group, compared with the data of adolescents of the 2nd group, an increase in the number of carriers of two mutant alleles at the locus rs 1048943 (gene CYP1A1) is 3.08 times, rs 464621 (gene CYP1A1) is 1. 8 times; locus rs 2069522 (CYP1A2 gene) 3.63 times; locus rs 1799853 (CYP2C9 * 2 gene) 4.5 times; locus rs 1057910 (gene CYP2C9 * 3) 3.8 times and locus rs 2279343 (gene CYP2B6) 4.25 times. Moreover, carriers of two normal alleles in adolescents of the first group at the locus rs 1048943 (gene CYP1A1) were 5.14 times; locus rs 2279343 (CYP2B6 gene) was 6.5 fold less than among adolescents of the 2nd group; and at the locus rs 464621 (gene CYP1A1), rs 2069522 (gene CYP1A2), rs 1799853 (gene CYP2C9 * 2), rs 1057910 (gene CYP2C9 * 3) there were no carriers of normal homozygotes. Conclusion. Group 1 adolescents with heavy metal contamination of the body are carriers significantly in a greater number of pathological mutations in the genes of the cytochrome P-450 detoxification system in comparison with data from group 2 adolescents.

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