Animal fats and human health

2003 ◽  
Vol 2003 ◽  
pp. 214-214 ◽  
Author(s):  
A.M. Salter

In 1991 it was recommended that total fat intake in the UK should be reduced to a population average of less that 33% of total daily energy intake and that saturated fatty acids should contribute no more than 10% of total energy (Department of Health, 1991). A further recommendation was that the intake of trans fatty acids should not exceed 2% of total energy. These recommendations were made primarily on the basis of the influence of fatty acids on plasma cholesterol and thereby on the development of cardiovascular disease. While associations of fat intake with other chronic diseases such as cancer, obesity and diabetes have also been suggested, it was felt that there was insufficient evidence to make specific recommendations on the basis of such claims. A reduction in saturated fat intake has remained a central target of public health nutrition within the United Kingdom ever since. Despite concerted efforts, particularly throughout the 1990s., to achieve these targets little progress has been made. In 2000, total fat intake remained at 38% and saturated fatty acid intake at 15% (DEFRA, 2001).

2001 ◽  
Vol 85 (3) ◽  
pp. 333-341 ◽  
Author(s):  
Gösta Samuelson ◽  
Lars-Erik Bratteby ◽  
Rawya Mohsen ◽  
Bengt Vessby

The objective of the present study was to describe the intake of dietary fatty acids among healthy 15-year-old boys and girls and to relate the intake of specific fatty acids and the fatty acid composition of the serum cholesterol esters to serum lipid, apolipoprotein (Apo) and insulin concentrations respectively. Fifty-two girls and forty-two boys were randomly selected from the official population register. Unexpectedly, significant inverse associations were found between the dietary content of saturated fatty acids with a chain length of four to fifteen C atoms, mainly derived from milk fat, as well as the corresponding fatty acids in the serum cholesterol esters, on the one hand and the serum concentrations of cholesterol and ApoB on the other. The estimated dietary intake of 4:0–10:0, 12:0 and 14:0 respectively, were all significantly inversely related to the serum cholesterol (r-0.32,r-0.31,r-0.30, all P<0.05) and ApoB (r-0.42,r-0.42, andr-0.40, all P<0.05) concentrations in girls and 12:0 to the ApoB concentration (r-0.55, P<0.01) in boys. The proportions of 12:0 and 15:0 in the serum cholesterol esters were negatively correlated with the serum cholesterol concentrations in both girls (r-0.34,r-0.32, P<0.05) and boys (r-0.53, P<0.01;r-0.32, P<0.05) and with the ApoB concentrations among boys (r-0.61, P<0.01;r-0.43, P<0.05). It is conceivable that milk fat contains or is associated with some component in the diet, or some other characteristics of the food intake, which counterbalances the expected positive relationships between saturated fat intake and lipid levels.


Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1493 ◽  
Author(s):  
Alicia Julibert ◽  
Maria Bibiloni ◽  
Cristina Bouzas ◽  
Miguel Martínez-González ◽  
Jordi Salas-Salvadó ◽  
...  

Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55–75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3–1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia.


1995 ◽  
Vol 74 (4) ◽  
pp. 509-521 ◽  
Author(s):  
Lars B. Nielsen ◽  
Per Leth-Espensen ◽  
Børge G. Nordestgaard ◽  
Eline Forged ◽  
Knud Kjeldsen ◽  
...  

The aim was to compare the effect on atherogenesis of dietary monounsaturated and saturated fatty acids in cholesterol-clamped rabbits. To obtain an average plasma cholesterol concentration of 20 mmol/l in each rabbit during the 13-week cholesterol-feeding period, dietary cholesterol was adjusted weekly. The amount of fat fed daily was 10 g per rabbit in Expts A (n 23), C (n 36), and D (n 58) and 5 g per rabbit in Expt B (n 24). The source of monounsaturated fatty acids was olive oil in all four experiments. The source of saturated fatty acids was butter in Expt A, lard in Expt B, coconut oil in Expt C, and butter or lard in Expt D. Generally, olive oil-fed groups received more cholesterol and tended to have more cholesterol in VLDL and less in LDL compared with groups receiving saturated fat. Analysis of variance of the combined results of all four experiments showed that, in comparison with saturated fat, olive oil lowered aortic cholesterol by 13 (−9–30, 95% confidence interval) % in the aortic arch, and by 10 (−10–26) % in the thoracic aorta, which was not significant. In the comparison with olive oil, no differences in effects on aortic cholesterol content were detected between butter, lard and coconut oil. These findings do not support the view that replacement of dietary saturated fat with olive oil has a major impact on the development of atherosclerosis in addition to that accounted for by changes in plasma cholesterol levels.


2013 ◽  
Vol 25 (1) ◽  
pp. 217
Author(s):  
V. Van Hoeck ◽  
P. E. J. Bols ◽  
M. Arias Alvares ◽  
E. Merckx ◽  
S. Andries ◽  
...  

In humans, diets rich in carbohydrates and saturated fatty acids are common and the subsequent altered metabolism has been linked to reduced fertility. Also, modern dairy cows are fed milk-stimulating diets rich in starch and fatty acids. The pre-implantation embryo is vulnerable to nutritionally induced changes in its micro-environment. We have shown that a dietary induced hyperlipidemia has detrimental consequences on development, quality and gene expression patterns of the pre-implantation embryo (Leroy et al. 2010 Hum. Reprod. 25, 768–778). Hyperlipidemia was induced by feeding starch- and saturated-fat-rich diets and the collected serum was added during bovine embryo culture. In the present study, we hypothesized that changing the saturated into a polyunsaturated fat source could alleviate these negative effects. We furthermore hypothesized that the sequence in which the different fat sources are given can affect embryo development and quality. Therefore, in the first setup: bovine zygotes (n = 1104; 4 replicates) were cultured in SOF medium supplemented with 10% serum collected from 3 synchronized heifers after 3 successive dietary treatments each fed during 4 weeks: control serum after a hay-based maintenance diet, saturated serum (SAT1) after a carbohydrate rich diet supplemented with saturated fatty acids (twice maintenance, C16 : 0, palmitic acid, 4.5% total fat), or unsaturated serum (UNSAT1) after a carbohydrate-rich diet supplemented with unsaturated fatty acids (twice maintenance, C18 : 3, linolenic acid, 4.45% total fat). In the second setup (n = 1483; 5 replicates): bovine zygotes were cultured in SOF medium supplemented with 10% serum from 3 synchronized heifers successively fed the 3 same dietary treatments in different order: control, unsaturated (UNSAT2), or saturated serum (SAT2). Day 7 blastocyst developmental competence (binary logistic regression), total cell number, and apoptotic cell ratio (ACR) (mixed model ANOVA) were evaluated. Supplementation of SAT1 serum in culture significantly reduced blastocysts from cleaved zygotes (36.7% v. 44.7%) and significantly increased ACR (0.1% ± 0.05 v. 0.06% ± 0.04) compared to controls (P < 0.05). Zygotes cultured in UNSAT1 displayed a significant higher cell number than control and SAT1 blastocysts (126.4 ± 25.7 v. 120.4 ± 24.3 and 108.3 ± 15.5, respectively; P ≤ 0.05) and lower ACR compared to SAT1 blastocysts (0.06% ± 0.03 v. 0.1% ± 0.05; P < 0.05). However, UNSAT1 zygotes showed a tendency for reduced development into blastocysts compared to control zygotes (P = 0.05). By contrast, UNSAT2 serum significantly improved blastocysts development from cleaved zygotes (40.0% v. 26.7%) and led to a lower ACR (0.06% ± 0.04 v. 0.1% ± 0.05) compared to SAT2 embryos (P < 0.05). In conclusion, our study confirmed the negative effects diets rich in starch and saturated fat on pre-implantation embryo development and quality. Changing the fat source to polyunsaturated eliminated these negative effects. Furthermore, we showed that the order in which different fat types are fed affects the zygote’s ability to sustain further development.


2002 ◽  
Vol 88 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Peter Sanderson ◽  
Jason M. R. Gill ◽  
Chris J. Packard ◽  
Thomas A. B. Sanders ◽  
Bengt Vessby ◽  
...  

The UK Food Standards Agency convened a group of expert scientists to review current research investigating the optimal dietary intake forn-9cis-monounsaturated fatty acids (MUFA). The aim was to review the mechanisms underlying the reported beneficial effects of MUFA on CHD risk, and to establish priorities for future research. The issue of optimal MUFA intake is contingent upon optimal total fat intake; however, there is no consensus of opinion on what the optimal total fat intake should be. Thus, it was recommended that a large multi-centre study should look at the effects on CHD risk of MUFA replacement of saturated fatty acids in relation to varying total fat intakes; this study should be of sufficient size to take account of genetic variation, sex, physical activity and stage of life factors, as well as being of sufficient duration to account for adaptation to diets. Recommendations for studies investigating the mechanistic effects of MUFA were also made. Methods of manipulating the food chain to increase MUFA at the expense of saturated fatty acids were also discussed.


Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3547
Author(s):  
Cathriona Monnard ◽  
Mathilde Fleith

This work reviews available data on dietary intakes of total fat, saturated fatty acids (SFA) and individual polyunsaturated fatty acids (PUFA) in children in different countries worldwide and for the first time, compares them with recent international recommendations. Studies published before June 2021 reporting total fat, total SFA and individual PUFA intakes in children aged 1–7 y were included. Observed intakes were evaluated against FAO/WHO and EFSA recommendations. 65 studies from 33 countries were included. Fat intake was too low in 88% of studies in young children (1–3 y). SFA intake was >10%E in 69–73% of children, especially in Europe. Linoleic acid intake was <3%E in 24% of studies in 1–2 y olds and within FAO/WHO recommendations among all other ages. Alpha-linolenic acid intake was <0.5%E in almost half of studies. Docosahexaenoic acid (DHA) or eicosapentaenoic acid + DHA intakes were below recommendations in most studies. In summary, while total fat intake was too low among younger children, SFA intake was above, especially in Europe and n-3 PUFA intake, especially DHA, were below recommendations for all ages. Intake of n-3 PUFA, especially DHA, is generally suboptimal. More data, particularly from developing countries, are required to refine these findings and guide implementation of adapted nutrition policies.


Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 3073 ◽  
Author(s):  
SuJin Song ◽  
Jae Eun Shim

We analyzed the trends in dietary intake of total fat and fatty acids among Korean adolescents during 2007–2017. A total of 6406 adolescents from the 2007–2017 Korea National Health and Examination Surveys were selected. Total fat and fatty acids intakes were calculated based on single 24-hour recall data and presented as grams (g) and percentage of energy intake (% kcal) across the survey period. Linear trends in intake across the survey period were compared using the multiple regression model. Total fat intake increased during the 11-year period from 54.3 g (21.7% kcal) to 61.8 g (25.2% kcal). Saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) intakes changed from 17.8 g (7.1% kcal) and 17.2 g (6.8% kcal) to 20.6 g (8.4% kcal) and 20.7 g (8.4% kcal) over time, respectively. For polyunsaturated fatty acids (PUFA), n-3 fatty acid intake did not change during the survey period. The proportions of individuals who had total fat and SFA above the recommendations increased across the survey period: 13.7% to 27.5% for total fat and 36.0% to 49.7% for SFA. Among Korean adolescents, dietary fat intake increased over time and the increases in SFA and MUFA intake were prominent. Monitoring dietary fat intake is helpful to suggest dietary guidelines and health policies.


Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3305
Author(s):  
Arne Astrup ◽  
Nina Teicholz ◽  
Faidon Magkos ◽  
Dennis M. Bier ◽  
J. Thomas Brenna ◽  
...  

The last decade has seen nearly 20 papers reviewing the totality of the data on saturated fats and cardiovascular outcomes, which, altogether, have demonstrated a lack of rigorous evidence to support continued recommendations either to limit the consumption of saturated fatty acids or to replace them with polyunsaturated fatty acids. These papers were unfortunately not considered by the process leading to the most recent U.S. Dietary Guidelines for Americans, the country’s national nutrition policy, which recently reconfirmed its recommendation to limit saturated fats to 10% or less of total energy intake, based on insufficient and inconsistent evidence. Continuation of a cap on saturated fat intake also fails to consider the important effects of the food matrix and the overall dietary pattern in which saturated fatty acids are consumed.


PEDIATRICS ◽  
1990 ◽  
Vol 86 (4) ◽  
pp. 520-526 ◽  
Author(s):  
R. Sue McPherson ◽  
Milton Z. Nichaman ◽  
Harold W. Kohl ◽  
Debra B. Reed ◽  
Darwin R. Labarthe

To investigate the nutrient intake and food use patterns among schoolchildren, diet was assessed among 138 children and adolescents in grades 5 through 12 using three random, nonconsecutive, 1-day food records. Mean intake of total fat, saturated fat, and polyunsaturated fat as percent of calories was 35.6%, 13.4%, and 6.6%, respectively. Among all subjects, 17% consumed diets containing &lt;30% of calories from fat, 34% consumed3≥8% of calories from fat, 7% consumed &lt;10% of calories from saturated fatty acids, and &gt;97% ate &lt;300 mg of cholesterol per day. While intake of calories, sodium, and β-carotene per 1000 kcal was higher in subjects consuming higher fat diets, intake of other micronutrients was either higher among those eating low-fat diets or did not differ by level of fat intake. Differences were seen in the amount of saturated fat and cholesterol that individual food sources contributed to the diets of subjects eating high and low fat diets. These cross-sectional data show that a substantial proportion of children and adolescents in this population are consuming diets low in fat and cholesterol without systematic differences in intake of other nutrients, suggesting that current dietary guidelines regarding fat intake are attainable within the current food use pattern of healthy, school-aged children and adolescents.


2021 ◽  
Vol 22 (3) ◽  
Author(s):  
Nadia Lingiardi ◽  
◽  
Yaela Dalessando ◽  
Florencia Lo Piccolo ◽  

Introduction: the evidence showed that fats have a role in diabetes development. Even though fat ideal amount in this pathology`s treatments controversial; it is known that fat quality is more important that fat quantity. Objectives: to assay the fat intake in type 2 diabetes (T2D) patients who attended in a health care center in Rosario. Materials and methods: a descriptive, observational and cross-sectional study was conducted. The sample included 88 male and female adults, with T2D aged 45.55±12.33. The total energy, total fat, satured, unsatured fatty acids and cholesterol intakes were estimated through three 24-hour food recall instruments and then were compared with recommended values. Statistical analysis was performed using R statistical software 4.0.2 version. Results: mean total energy intake was 1851 kcal. Mean total fat intake was 43.30%, satured fatty acid intake 13.44%, monounsatured 14.10%, polyunsatured 12.86% and choresterol 388.55 mg. Total fat, satured and monounsatured fatty acids and cholesterol intakes were significantly higher in men (p=0.008, p=0.004, p=0.023, p=0.027; respectively). The 78.41% exceeded total fat intake. Satured fatty acid intake was inadequate in 99% of participants. The 92% had a monounsatured intake adequate to recommendations. Polyunsatured fatty acid showed an inadequate intake in 68% of patients. Cholesterol intake was inadequate in 83% of participants. There were not found significant differences in adherence to recommendations between sex. Conclusions: more than a half of T2D patients show and excessive total fat intake with inadequate intakes of saturated and polyunsaturated fatty acids and cholesterol. Only monounsaturated fat intake was adequate to recommendations.


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