Biflorin, Isolated from the Flower Buds of Syzygium aromaticum L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock

2016 ◽  
Vol 79 (4) ◽  
pp. 711-720 ◽  
Author(s):  
Hwi-Ho Lee ◽  
Ji-Sun Shin ◽  
Woo-Seok Lee ◽  
Byeol Ryu ◽  
Dae Sik Jang ◽  
...  
2012 ◽  
Vol 3 (3) ◽  
pp. 323 ◽  
Author(s):  
Shakir Ali ◽  
TijjaniSalihu Shinkafi ◽  
Indusmitha Routray ◽  
Tasleem Ahmad ◽  
Amena Mahmood

Author(s):  
Rajalekshmy V. S. ◽  
V. Manimekalai

Objective: To analyse and compare the major chemical components in the flower buds, pedicels and leaves of Syzygium aromaticum by Gas-Chromatography Mass spectrometry technique. Methods: Healthy and mature flower buds, pedicels and leaves were shade dried and pulverized using a mechanical grinder. The powder was successively extracted with ethanol (40-60o C). The extracts were concentrated under reduced pressure in a rotary evaporator. The ethanolic extracts of the plant parts such as leaves, pedicels, and buds were used for GC-MS analysis.Results: The major constituent is eugenol. Pedicels contain 79.75% eugenol, buds contain 74.12% eugenol and leaves contain 51.03% eugenol. In addition to eugenol, other important components are Acetyl eugenol, Caryophyllene, Humulene and Caryophyllene oxide.Conclusion: Eugenol has a wide range of medicinal properties such as antiseptic, anaesthetic, analgesic anti-inflammatory. Commercially pedicel is not used for eugenol extraction. Present study has revealed that it could be used as a promising one in pharmaceutical industry in addition to flower buds.


RSC Advances ◽  
2014 ◽  
Vol 4 (106) ◽  
pp. 61927-61935 ◽  
Author(s):  
Brian R. Donovan ◽  
Jared S. Cobb ◽  
Ethan F. T. Hoff ◽  
Derek L. Patton

This paper reports the synthesis of catechol-functionalized thiol–ene networks as photocurable adhesives, where adhesive interactions are derived from 4-allylpyrocatechol – an alkene readily obtained from Syzygium aromaticum flower buds (clove oil).


2021 ◽  
Vol 15 (3) ◽  
pp. 327-334
Author(s):  
Patience Fankem Mekemzeu ◽  
Sylvie Kwanga Nguikwie ◽  
François Nguimatsia ◽  
Samanta Lafortune Mbouwe Chouela ◽  
Bienvenue Gnowe Bawane ◽  
...  

In order to provide an effective alternative for efficient management of dermatophytosis, we evaluate in vitro the antioxidant and antiradical potentials of the essential oil of the dry flower buds of Syzygium aromaticum and its antidermatophytic activity against Epidermophyton floccosum and Trichophyton soudanense, For this purpose, the essential oil was obtained by hydrodistillation through a Clevenger apparatus and the antioxidant and antiradical potentials were evaluated by the ferric reducing antioxidant power (FRAP) and the trapping of the ABTS•+ radical methods, respectively. The evaluation of the antidermatophytic activity was made by the agar incorporation method. The results showed that the essential oil reduced ferric iron (Fe3+) to ferrous iron (Fe2+) in a more significant manner than BHT (reference antioxidant). Moreover, the antiradical power of the essential oil was twice greater than that of BHT. Furthermore, the essential oil inhibited the mycelial growth of the two dermatophytes, with 500 ppm and 1000 ppm of minimal inhibitory concentrations against Epidermophyton floccosum and Trichophyton soudanense, respectively. This activity was greater than that of griseofulvin whose minimal inhibitory concentration was greater than 4000 ppm against both studied germs. These findings show that, withon the framework of safeguarding human lives and protecting the environment, the essential oil from the dry flower buds of Syzygium aromaticum appeared as reliable alternative for the treatment of dermatophytosis caused by Epidermophyton floccosum and Trichophyton soudanense. Our results lay scientific foundation toward the promotion and development of Cameroonian biodiversity in treatments of dermatophytosis.


2016 ◽  
Vol 64 (15) ◽  
pp. 3048-3053 ◽  
Author(s):  
Byeol Ryu ◽  
Hye Mi Kim ◽  
Jin Su Lee ◽  
Chan Kyu Lee ◽  
Jurdas Sezirahiga ◽  
...  

2019 ◽  
Vol 10 ◽  
Author(s):  
Thimappa Ramachandrappa Lakshmeesha ◽  
Naveen Kumar Kalagatur ◽  
Venkataramana Mudili ◽  
Chakrabhavi Dhananjaya Mohan ◽  
Shobith Rangappa ◽  
...  

2011 ◽  
Vol 66 (2) ◽  
pp. 394-399 ◽  
Author(s):  
Minpei Kuroda ◽  
Yoshihiro Mimaki ◽  
Takayuki Ohtomo ◽  
Junji Yamada ◽  
Tozo Nishiyama ◽  
...  

Author(s):  
Matseu Sakou Gerardine Noël ◽  
Ngatanko Illiassa ◽  
Kouninki Habiba ◽  
Nukenine Nchiwan Elias

The bioinsecticidal effect of powders and essential oils of S. aromaticum (L.) flower buds and V. heterophylla (Engl.) leaves against adult cowpea weevil C. maculatus was studied. Powders were tested by direct contact only while essential oils were tested by direct contact and indirect contact (inhalation and repellency). In 500 mL glass jars, the individual and combined powders were applied to 100 g of cowpea seeds at 0.5 g, 1 g, 1.5 g and 2 g doses for both leaves and flower buds of V. heterophylla and S. aromaticum respectively. The essential oils were also applied individually and after equilibrium combination on 50 g of cowpea at 4 µL/mL, 8 µL/mL, 12 µL/mL, 16 µL/mL. All the infestations were then achieved by adding 20 bruchids of 48 h old. The essential oil obtained was purified and analyzed with Gas Chromatography and Mass Spectrometry (GC-MS). 72 h after the individual treatment, 100% mortality was obtained at 2 g dose for V. heterophylla and 0.5 g dose for S. aromaticum compared to the control jars (1%). The combined powders were found to be more effective with 100% of mortality at a dose 1 g after 48 h of exposure. For essential oils, 100% and 90% of mortality were obtained respectively at 8 µL/mL dose for S. aromaticum (160 µL/kg) and 16 µL/mL dose for V. heterophylla (320 µL/kg) 72 h after treatment. In addition, the essential oil of S. aromaticum showed relatively higher repellant properties with an average repellency percentage of PR = 89.37% than that of V. heterophylla (PR = 70.62%). 100% of mortality was induced after inhalation of essential oils of S. aromaticum and V. heterophylla at doses 10 µL and 40 µL respectively after 72 h of exposure time. The results obtained from the GC-MS showed that the major components in the essential oil of S. aromaticum were eugenol (83.40%) although that of V. heterophylla were Spathulenol (23.66%), Beta-Caryophyllene oxide (16.46%) and 6-Isopropenyl-4 (16.30%). The powders and essential oils of the tested plants applied individually or after equilibrium combination showed interesting prospects for controlling Callosobruchus maculatus and effectively preserving cowpea seeds in storage warehouses.


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