Zinc–Carboxylate Binding in Mixed Octadecanoic Acid and Octadecanol Monolayers on Proxy Seawater Solution Surfaces

All parts of A. indica (neem) and R. communis (castor) plants have mostly been used as natural remedies in the control and treatment of several ailments, control of pests and insects, animal feeds and production of industrial products globally. The seed oils of A. indica and R. communis are known to have antidiabetic, anti-helminthic, antifertility, antioxidant, antibacterial, anti-inflammatory, anti-cancer, insecticidal and mosquitocidal activity. This study reports for the first time the chemical composition of A. indica and R. communis seed oils from Marigat, Baringo County, Kenya. Seed oils of A. indica and R. communis were extracted from mature dried seeds through cold pressing and boiling respectively and chemical composition determined using Gas Chromatography (GC)-Mass Spectrometry (MS). The constituents of both seed oils were dominated by saturated and unsaturated fatty acids, cyclic esters and methyl esters. The predominant constituents of R. communis were (Z)-6-Octadecenoic acid (37.33%), Ricinoleic acid (30.22%) and 13-Hexyloxacyclotridec-10-en-2-one (26.67%) while those of A. indica were 2-hexyl-1-decanol (30.97%), Octadecanoic acid (29.69%) and Oxalic acid, 6-ethyloct-3-yl ethyl ester (15.55%). Oils contained Hexadecanoic acid and Octadecanoic acid which are used in the manufacture of several products such as candles, soaps, lotions, perfumes and cosmetics. Octadecenoic acid is important in control of human diseases and Ricinoleic acid in production of alkyd resins for surface coating and biofuel. From the results, A. indica and R. communis seed oils constituents have potential in the agricultural, industrial, comestics and pharmaceutical sectors but require further fractionation to isolate the bioactive compounds.

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Addition of Quantitative 3-Hydroxy-Octadecanoic Acid to the Stable Isotope Gas Chromatography-Mass Spectrometry Method for Measuring 3-Hydroxy Fatty Acids

Clinical Chemistry ◽

10.1093/clinchem/48.1.176 ◽

2002 ◽

Vol 48 (1) ◽

pp. 176-179 ◽

Cited By ~ 8

Author(s):

Patricia M Jones ◽

Susan Tjoa ◽

Paul V Fennessey ◽

Stephen I Goodman ◽

Michael J Bennett

Keyword(s):

Mass Spectrometry ◽

Fatty Acids ◽

Gas Chromatography ◽

Stable Isotope ◽

Hydroxy Fatty Acids ◽

Gas Chromatography Mass Spectrometry ◽

Octadecanoic Acid ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Mass Spectrometry

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Measurement and Correlation of the Solid−Liquid−Gas Equilibria for Carbon Dioxide + Octadecanoic Acid (Stearic Acid) and Carbon Dioxide + 1-Octadecanol (Stearyl Alcohol) Systems

Journal of Chemical & Engineering Data ◽

10.1021/je9005272 ◽

2010 ◽

Vol 55 (2) ◽

pp. 925-929 ◽

Cited By ~ 14

Author(s):

Hirohisa Uchida ◽

Tetsuo Kamijo

Keyword(s):

Carbon Dioxide ◽

Stearic Acid ◽

Stearyl Alcohol ◽

Octadecanoic Acid ◽

Solid Liquid

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Metabolite profiling of tartary buckwheat-an underutilized neutraceutical crop of Kashmir Himalaya

Journal of Phytology ◽

10.19071/jp.2016.v8.3106 ◽

2017 ◽

Vol 8 ◽

pp. 49 ◽

Cited By ~ 1

Author(s):

Tanveer Bilal Pirzadah ◽

Bisma Malik ◽

Inayatullah Tahir ◽

Reiaz Ul Rehman

Keyword(s):

Metabolite Profiling ◽

Well Being ◽

Tartary Buckwheat ◽

Octadecanoic Acid ◽

Food Sector ◽

Fagopyrum Tataricum ◽

Promising Alternative ◽

Hull Extract ◽

Pharmaceutical Properties ◽

Excellent Source

The aim of the present study was to explore the possible metabolites in the methanolic extract of root, stem, groat and hull of the neutraceutical crop, Fagopyrum tataricum using GC-MS technique. From GC-MS metabolite profiling, over 90 different metabolites were identified among root, stem, groat and hull extract. The most prevailing compounds were 3, 3’, 4’, 5, 7-pentahydroflavone-3-rhamnoglucoside (71.94%) in groat, 9, 12-octadecadienoic acid (49.38%) in root, 6-octadecanoic acid, a steric acid (70.46%) in hull and Cis-9-hexadecanal (13.38%) in stem. Present investigation reveals that F. tataricum is an excellent source of many metabolites such as, fatty acids, hydrocarbons, steroids, terpenoids, esters, organic acids and aldehydes with excellent pharmaceutical properties. These results suggest that tartary buckwheat could be a promising alternative in the functional food sector and neutraceutical to improve social well-being and diminish malnutrition.

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Prediction aided in vitro analysis of octadecanoic acid from Cyanobacterium Lyngbya sp. as a proapoptotic factor in eliciting anti-inflammatory properties

Bioinformation ◽

10.6026/97320630013301 ◽

2017 ◽

Vol 13 (09) ◽

pp. 301-306

Author(s):

Paramasivan Manivannan ◽

◽

Gangatharan Muralitharan ◽

Nainangu Prasanna Balaji ◽

◽

...

Keyword(s):

Octadecanoic Acid ◽

Anti Inflammatory ◽

Vitro Analysis ◽

In Vitro Analysis

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Evaluation of the Antibacterial Activities of Isolated Bioactive Components from the plant Adenodolichos paniculatus

Journal of Phytomedicine and Therapeutics ◽

10.4314/jopat.v19i2.4 ◽

2021 ◽

Vol 19 (2) ◽

pp. 429-447

Author(s):

A.E. Onwuliri ◽

I.F. Kyahar ◽

J.O. Ehinmidu ◽

P.O. Oladosu

Keyword(s):

Staphylococcus Aureus ◽

Pseudomonas Aeruginosa ◽

Stearic Acid ◽

Streptococcus Pyogenes ◽

Antibacterial Activities ◽

Bioactive Components ◽

Octadecanoic Acid ◽

Zones Of Inhibition ◽

Rf Values ◽

Component C

The three bioactive components isolated included: component A (major phytochemicals were Bis (2-ethylhexyl) phthalate (16.36 %), 9,12-Octadecadienoic acid, ethyl ether (14.77 %) and 9.cis., 11.trans.-octadecadie noate (14.77 %), component B (major phytochemicals were 9,12-Octadecadienal (Linoleic acid) (40.98 %), Octadecanoic acid (Stearic acid) (9.26 %), Undecanoic acid, 10-bromo- (10-bromoudecanoic acid) (9.26 %) and n-Hexadecanoic acid (Palmitic acid) and component C (cis-9-octadecenoic acid (Oleic Acid) (30.45 %), Octadecanoic acid (Stearic acid) (17.33 %)). These components isolated from the chloroform fraction of Adenodolichos paniculatus are used by traditional medicinal practitioners for the management of mouth and throat infections. The antibacterial activities against Streptococcus pyogenes, Staphylococcus aureus and Pseudomonas aeruginosa were evaluated using bioautography and agar-well diffusion methods. The bioautogram result showed that component A had inhibited spots against S. pyogenes (17.50 mm) and P. aeruginosa (16.00 mm), corresponding to the TLC spots with Rf values of 0.594, 0.55 and 0.26, respectively. Component B showed inhibition spots against Streptococcus pyogenes (36.50 mm), Staphylococcus aureus (16.00 mm) and Pseudomonas aeruginosa (11.00 mm), corresponding to the TLC spots with Rf values 0.891, 0.87, 0.85 and 0.25, respectively. Component C showed inhibition spots against Streptococcus pyogenes (16.50 mm), Staphylococcus aureus (15.00 mm) and Pseudomonas aeruginosa (10.50 mm), corresponding to the TLC spots Rf values of 0.938, 0.44, 0.21 and 0.90, respectively. For the agar-well diffusion method, component A at 1 mg/ml inhibited Streptococcus pyogenes, Staphylococcus aureus and Pseudomonas aeruginosa growths with zones of inhibition 23.0, 19.5 and 17.50 mm, respectively. MIC and MBC of component A were 125, 250 and 250 and 250, 500 and 500 μg/ml, respectively. Component B at 1 mg/ml inhibited Streptococcus pyogenes, Staphylococcus aureus and Pseudomonas aeruginosa growth with zones of inhibition 30.0, 28.0 and 18.5 mm, respectively. MIC and MBC of the compound B were 31, 62 and 125 and 62, 125 and 250 μg/ml, respectively. Component C at 1 mg/ml inhibited Streptococcus pyogenes, Staphylococcus aureus and Pseudomonas aeruginosa growth with zones of inhibition 24.5, 20.5 and 17.0 mm, respectively. MIC and MBC of the component C were 62, 125 and 250 and 125, 250 and 500 μg/ml, respectively. This study confirmed that bioactive compounds of A. paniculatus root have antibacterial properties and support the use of this part of the plant as a traditional remedy for mouth and throat infections possibly caused by the test bacteria.

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SKRINING SENYAWA METABOLIT SEKUNDER DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETILASETAT DAUN WEDUSAN (Eupatorium odoratum)

Molekul ◽

10.20884/1.jm.2009.4.2.67 ◽

2009 ◽

Vol 4 (2) ◽

pp. 94

Author(s):

Purwati Purwati ◽

Undri Rastuti

Keyword(s):

Antioxidant Activity ◽

Ethyl Acetate ◽

Research Method ◽

Oxidation Process ◽

Ethyl Acetate Extract ◽

Natural Process ◽

Inhibition Activity ◽

Octadecanoic Acid ◽

Fat Quality

Oxidation process is a natural process which always occurs in fat. The process affects and decreases the fat quality. Oxidation in fat can be hampered by the addition of antioxidant. Antioxidant activity of wedusan leaf has to be studied to know the possibility of wedusan leaf as an antioxidant. Hence, the aims of the research were to determine the antioxidant activity of ethyl acetate extract of wedusan leaf using TBA method, and to compare the antioxidant activity of wedusan leaf and that of BHT. The research method consisted of sample preparation, extraction, and determination of antioxidant activity using TBA method. Wedusan leaf was extracted by maceration using n-hexane and ethyl acetate solvents. The n-hexane extract was 2.90 gram, whereas ethyl acetate extract was 13.12 gram. Based on qualitative screening on secondary metabolites, ethyl acetate extract contained flavonoid. The results from GC-MS indicated that ethyl acetate extract contained methyl heptadecanoic, methyl-13-octadecenoic, 14,16-octadecadienal, and octadecanoic acid. The order of inhibition activity of antioxidant were 0.05% (w/v) of BHT > 0.15% (w/v) of ethyl acetate extract > 0.10% (w/v) of ethyl acetate extract > 0.05% (w/v) of ethyl acetate extract.

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