No Difference in Magnesium Intake between Obese Women and Healthy Controls

2019 ◽  
Vol 89 (3-4) ◽  
pp. 118-124
Author(s):  
Jennifer Beatriz Silva Morais ◽  
Taynáh Emannuelle Coelho de Freitas ◽  
Juliana Soares Severo ◽  
Ana Raquel Soares de Oliveira ◽  
Kyria Jayanne Clímaco Cruz ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Dietary Intake ◽  
Body Mass ◽  
Energy Homeostasis ◽  
Cross Sectional Study ◽  
Control Group ◽  
Obese Women ◽  
Cross Sectional ◽  
And Control ◽  
Macronutrient Distribution

Abstract. Magnesium is a predominantly intracellular ion and plays an important role in energy metabolism and in the maintenance of energy homeostasis. This study aimed to estimate the dietary intake of magnesium and its association with adiposity parameters in obese women. This cross-sectional study included 125 women, aged between 20 and 50 years, who were divided into two groups: obese group (n = 62) and control group (n = 63). The control group was age-matched. Adiposity parameters determined were weight, body mass index and waist circumference as well as the intake of calories, macronutrients, and magnesium were calculated. The cut-off for obesity was body mass index between 30.0 and 39.9 kg/m2 and for control group was between 18.5 and 24.9 kg/m2 Food intake was calculated using 3-day food records, and energy consumption as well as the intake of macronutrients and magnesium was calculated using the NutWin software version 1.5. The reference values used were the Acceptable Macronutrient Distribution Range for macronutrients and the Estimated Average Requirement (EAR) for magnesium. The average levels of magnesium found in the diet were lower than those recommended (169.1 ± 64.5 mg Mg/day and 158.5 ± 42.9 mg Mg/day, for obese women and control group, respectively) and the differences between the groups were not statistically different (p > 0.05). The correlation analysis indicated that the association between the dietary intake of magnesium and adiposity was not significant. The results of this study indicate that dietary magnesium does not influence the adiposity parameters in obese women.

scholarly journals EFFECT OF LEPR AND GR GENE POLYMORPHISMS ON HEALTH STATUS OF MOTHERS WITH METABOLIC DISORDERS AND THEIR NEWBORNS

2020 ◽  
Vol 20 (3) ◽  
pp. 20-25
Author(s):  
V.I. Pokhуlko ◽  
Yu.I. Cherniavska ◽  
S.M. Tsvirenko ◽  
Z.I. Rossokha ◽  
Yu.Yu. Klymchiuk
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Gene Polymorphisms ◽  
Metabolic Disorders ◽  
Cross Sectional Study ◽  
Control Group ◽  
Genetic Determinants ◽  
Cross Sectional ◽  
Prevalence Of Obesity

The high prevalence of obesity and metabolic syndrome throughout the world over the past two decades provided the grounds to the WHO to consider overweight as a non-infectious pandemic. Among the factors that negatively affect the metabolism, result in metabolic disorders and obesity there are genetic, prenatal, diet-related, somatic, psychogenic and others. Analysis of LEPR and GR gene polymorphisms among mothers and their newborns can be an important component in the prediction of metabolic disorders and obesity. The aim of this study was to analyze the presence of clinical and genetic determinants of metabolic syndrome in mothers and their newborns. Materials and methods. A cross-sectional study of 42 pairs of mothers and newborns was performed; we analyzed their anthropometric, clinical and laboratory parameters and, in particular, 2 types of genetic polymorphisms (LEPR rs1137101 and GR, BClI polymorphism). The main group consisted of 15 mother-child pairs, where the woman was clinically obese (body mass index more than 30), the comparison group included 27 mother-child pairs, where the women were overweight (body mass index more than 25). Results. Obese mothers were significantly more likely to have a miscarriage (p = 0.01). Children from obese mothers had significantly higher percentiles of birth weight compared to the control group (60.9 ± 7.7 and 49.75 ± 4.5, respectively, p = 0.05). The GG genotype of the GR gene was associated with more common indications for hospitalization (p = 0.012), rapid delivery (p = 0.01), umbilical cord entanglement around the neck of the foetus (p = 0.012). Among the children- carriers of the GG BclI genotype GR, cardio-metabolic disorders detected by the auscultation of the heart (arrhythmia, functional noise) were found out as significantly more frequent (p = 0.003). Conclusion. The study did not find the associations between LEPR and GR gene polymorphism in obese mothers and the development of overweight in their children, but the study revealed an adverse effect of polymorphic variants on obstetric and gynaecological status of mothers, labour and adaptation of infants in the early neonatal period.

scholarly journals Circulating ErbB3/HER3 Levels are Associated with Increased Risk of Hypertension with Overweight: A Cross-Sectional Study

2020 ◽  
Author(s):  
Lijun Zhu ◽  
Zhengmei Fang ◽  
Yuelong Jin ◽  
Weiwei Chang ◽  
Mengyun Huang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Body Mass Index ◽  
Body Mass ◽  
Conditional Logistic Regression ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Cross Sectional ◽  
Increased Risk

Abstract Background: Hypertension and overweight are both independent risk factors for cardiovascular disease，and being overweight can more likely to develop high blood pressure. Recent research has shown that ErbB3/HER3 played a considerable role in the development of cardiovascular disease. However, ErbB3 levels effects in the hypertensive overweight patients are unknown. This study aimed to assess the association between ErbB3 levels and hypertension with overweight in Chinese population. Methods: 128 Chinese adults aged 33-79 years, both sexes, underwent evaluation of height and weight, blood pressure, biochemical indicators and ErbB3 levels. Plasma ErbB3 levels was assessed by the Enzyme-linked immunosorbent assay (ELISA), and body mass index (BMI) was calculated as body weight divided by height squared. Participants were allocated in three groups according to blood pressure and BMI: healthy control group (CNT; n = 31; normotensive and nonoverweight), hypertension group (HT; n = 33; hypertension and nonoverweight) and hypertension with overweight group (HTO; n = 64; hypertension and overweight). A 2-tailed P<0.05 was defined to be statistically significant. Results: The difference in mean of ErbB3 levels in three groups was not significant, but had a linear decrease in males, in CNT (1.13±0.36), HT (1.03±0.36) and HTO (0.84±0.26) ng/ml, with P was 0.007. In drinking population, the ErbB3 was significantly reduced in the HTO group as compared with the CNT and HT groups (0.76±0.23 versus 1.18±0.37 and 1.20±0.30, respectively). ErbB3 levels was negatively correlated with DBP in males(r=-0.293, P=0.012), in smoking populations (r=-0.47, P=0.004) and drinking populations (r=-0.387, P=0.008). Besides, BMI in males and in drinking populations and UA in males presented negatively correlations with ErbB3 (p＜0.05). The multivariate conditional logistic regression showed that plasma ErbB3 levels was associated with reduced risk for HTO in males (OR 0.054; 95% CI: 0.007-0.412) and drink group(OR 0.002; 95% CI: 0.000-0.101). Conclusions：The apparent association between lower ErbB3 levels and overweight hypertensive patients suggested that ErbB3 may contribute to the pathogenesis to hypertension with overweight, with BMI, gender, and drinking all potentially modulating the process.Keywords: ErbB3; Hypertension; Overweight; Body mass index.

scholarly journals Association of Obesity with Hypertension in Adult Female

2017 ◽  
Vol 28 (1) ◽  
pp. 28-33
Author(s):  
Nahid Yeasmin ◽  
Sayeeda Mahmuda ◽  
Shamima Akther ◽  
Khadija Begum ◽  
Masud Salehin ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
Medical Problem ◽  
Cross Sectional Study ◽  
Control Group ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Female Subjects

Background: Incidence of hypertension in female is increasing throughout the world, leading to life threatening medical problem like cardiovascular diseases, stroke. An association between hypertension and obesity has been identified.Objectives : The study was carried out to observe the association of obesity with hypertension in adult female.Methods : This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of one hundred female subjects were selected with age ranging from30 to50 years. Among them 50 hypertensive female subjects were included from out-patient department of Medicine, Dhaka medical college Hospital, Dhaka as study group(B) and 50 apparently healthy female were taken as control group(A) for comparison Waist circumference(WC) was measured and body mass index (BMI) was calculated in both groups. Data was analyzed by Unpaired Student’s ‘t’ test and Pearson’s correlation co-efficient (r) test as applicable.Results: The value of waist circumference was higher in hypertensive subjects than those of nonhypertensive female and result was statistically significant. Body mass index value was significantly (p<0.001) higher in hypertensive subjects in comparison to those of non-hypertensive subjects. In hypertensive subjects waist circumference and body mass index values were higher and showed significant positive correlation with systolic and diastolic blood pressure. Conclusion: Present study revealed that hypertension has positive and significant relationship with waist circumference and body mass index.Bangladesh J Medicine Jan 2017; 28(1) : 28-33

scholarly journals Association between uterine leiomyoma with body mass index and parity in the women of coastal Karnataka, India

2020 ◽  
Vol 9 (2) ◽  
pp. 740 ◽  
Author(s):  
Amruta C. ◽  
Annappa Shetty ◽  
Naresh Pawaskar ◽  
Shreya Desai
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Uterine Leiomyoma ◽  
Benign Tumor ◽  
Cross Sectional Study ◽  
Obese Women ◽  
Sectional Study ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Reduced Risk

Background: Fibroid is the commonest benign tumor of the uterus and also commonest benign solid tumor in females. Fibroids are found to be 2-3 times more prevalent in obese women, specially the one’s with central obesity and in those with BMI > or = 35. Epidemiologic data also shows pregnancy is associated with reduced risk of fibroids. So, the present study will be a cross-sectional study which will be undertaken to know the association of uterine leiomyoma with BMI and parity in the women of coastal Karnataka.Methods: An analytical cross-sectional study was performed among the 100 patients attending OPD at the department of obstetrics and gynecology, Karwar institute of medical sciences from June 2018 to August 2018. Women suspected to have fibroid based on their symptoms were made to undergo ultrasonography. Comparison was made between the parity, body mass index of the patient and the size of the uterine fibroid visualized.Results: Out of 100 women studied 63 were nulliparous and 37 women were multiparous. Incidence of fibroid is inversely proportional to parity. When BMI < 18 only 6 women had fibroid, when BMI > 25, 57 women had fibroids and between 18-25 group 37 women were diagnosed with fibroid.Conclusions: The fibroid showed directly proportional association with BMI. Greater the BMI, more was the risk of fibroids. The fibroid showed inversely proportional association with parity. Greater the parity of the women lesser was her chances of being at risk of having fibroid.

scholarly journals The Relationship between Body Mass Index and Poor Self-rated Health in the Korean Population

2019 ◽  
Author(s):  
Eun-Seok Sung ◽  
Chang Kyun Choi ◽  
Ji-An Jeong ◽  
Min-Ho Shin
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Obese Women ◽  
Sampling Weights ◽  
Cross Sectional ◽  
Self Rated Health ◽  
Rate Ratios ◽  
The Relationship

AbstractObjectiveSeveral previous studies have evaluated associations between body mass index (BMI) and self-rated health (SRH); however, the results were inconsistent. This study aimed to examine the association between BMI and SRH in Korean adults.MethodsThe study was conducted in 214,997 adults who participated in the 2016 Korean Community Health Survey. Participants were categorized into four groups based on BMI: underweight (<18.5 kg/m2), normal weight (18.5–24.9 kg/m2), overweight (25.0–29.9 kg/m2), or obese (≥30.0 kg/m2). Multivariate Poisson regression analysis with sampling weights and robust variance estimators was performed to evaluate the relationship between BMI categories and poor SRH.ResultsThere was a J-shaped association between BMI and poor SRH in both sexes, with the lowest risk observed in the normal weight group in both sexes. Compared with normal weight subjects, the age and lifestyle adjusted prevalence rate ratios for poor SRH were 1.61 (95% CI, 1.50–1.74) for underweight, 1.16 (95% CI, 1.11–1.21) for overweight, and 2.35 (95% CI, 2.13–2.58) for obese men; and 1.24 (95% CI, 1.17–1.32) for underweight, 1.26 (95% CI, 1.22–1.31) for overweight, and 1.77 (95% CI, 1.64–1.91) for obese women.ConclusionsIn a cross-sectional study using a nationally representative survey, there was a nonlinear relationship between BMI and poor SRH. This relationship was more prominent in men than in women. Prospective studies are needed to further clarify the relationship between BMI and SRH.

Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome

2019 ◽  
pp. 68-73
Author(s):  
Trong Nghia Nguyen ◽  
Thi Nhan Nguyen ◽  
Thi Dua Dao
Keyword(s):  
Metabolic Syndrome ◽  
Medical Center ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D ◽  
Key Words Metabolic Syndrome ◽  
And Control

Background: The metabolic syndrome is a constellation of cardiometabolic risk factors that tend to cluster together in affected individuals more often than predicted by chance. The presence of the metabolic syndrome substantially increases the risk of developing type 2 diabetes and cardiovascular disease, and is associated with a range of adverse clinical outcomes, many of which are closely associated with aging. Current estimates suggest that approximately 20 - 25% of the world’s population is affected by the metabolic syndrome. The prevalence of the metabolic syndrome rises with age and more than 45% of people aged over 60 years have the metabolic syndrome. Recent studies show that low vitamin D status is very common in the world and this is a risk factor of metabolic syndrome. Objective: (1) Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome. (2) Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Material and method: A cross-sectional study with control group on 318 adult subjects for health examinations at International Medical Center at Hue Central Hospital, including 139 subjects with metabolic syndrome and control group of 179 healthy subjects. Metabolic syndrome was defined according to the IDF, NHLBI, AHA, WHF, IAS, IASO (2009). Plasma hydroxyvitamin D concentration was measured using chemiluminescent microparticle immunoassay. Reciever operating characteristic (ROC) curve were generated to assess sensitivity and specificity for different cut off value of 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Results: Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome was 26.4 ng/ml, incidence of plasma 25-hydroxyvitamin D deficiency (59.7%) was significantly higher than in control group (23.5%) (p < 0.001). The optimal cut off point for 25-OH-D concentration for predictor of metabolic syndrome as 26.4 ng/ml (AUC=0.657, sensitivity=53.4%, specificity=71.6%). Conclusion: In 139 subjects with metabolic syndrome, the plasma 25-hydroxyvitamin D concentration was 26.4 ng/ml and the incidence of 25-hydroxyvitamin D deficiency in the metabolic syndrome group was 59.7%. The optimal cut off point for plasma 25-hydroxyvitamin D concentration for predictor of metabolic syndrome as 26.4 ng/ml. Key words: Metabolic syndrome, 25-hydroxyvitamin D

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