Sexuell übertragbare Infektionen: Update 2013

Praxis ◽  
2013 ◽  
Vol 102 (5) ◽  
pp. 273-278 ◽  
Author(s):  
Stephan Lautenschlager

Trotz beachtlicher Fortschritte in Diagnostik, Therapie und Aufklärung sind sexuell übertragbare Infektionen (STI) weltweit und speziell auch in der Schweiz weiterhin zunehmend. Die häufigsten sexuell übertragbaren Erreger umfassen humane Papillomviren, Chlamydien, Herpes-simplex-Viren (Typ 1 und 2), Neisseria gonorrhoeae, Treponema pallidum, Hepatitis-B-Viren und Trichomonaden. Infolge des häufig asymptomatischen oder oligosymptomatischen Verlaufs bedeuten diese Infektionen sowohl diagnostisch als auch therapeutisch weiterhin eine grosse Herausforderung für das Gesundheitswesen. Erfreulicherweise konnten aktuelle epidemiologische Studien zu Infektionen mit humanen Papillomviren zeigen, dass geimpfte Frauen kaum noch an Kondylomen erkranken und ebenfalls deutlich seltener Zervix-Dysplasien aufweisen. Auf der anderen Seite ist die Zunahme von Urethritisfällen durch unterschiedliche Erreger sowie der Syphilis ungebrochen. Alarmierend ist zusätzlich die aktuelle Resistenzlage der Gonokokken, die zunehmend auf die Cephalosporine – die letzte verbleibende wirksame Antibiotikagruppe – eine reduzierte Empfindlichkeit aufweist. In dieser Situation sollten die aktuellen Therapierichtlinien streng eingehalten werden. Weitere aktuelle Trends und deren Konsequenzen werden im Artikel diskutiert.

2020 ◽  
Vol 61 (3) ◽  
pp. 227-241
Author(s):  
Jorge Cañarte Alcivar ◽  
Melina Moreano Zambrano ◽  
Mónica Guerrero Madroñero ◽  
Miguel Giler Zambrano ◽  
Diana Callejas Monsalve ◽  
...  

Las infecciones de transmisión sexual (ITS) y conductas sexualesde riesgo, son prevalentes en mujeres encarceladas. Este estudio mostróque las ITS fueron más frecuentes en mujeres reclusas (66,6 %) que en mujeresen libertad (p ≤ 0,001). Solo el grupo de encarceladas presentó combinacionesde ITS (39%) (p≤0,019), siendo significativas las infecciones por VPH (p≤0,007) y Chlamydia trachomatis (p≤ 0,003) con otros agentes causales. VPHy Chlamydia trachomatis fueron más frecuentes en reclusas (35,7%), mientrasque las mujeres libres presentaron 9,5% (p≤0,004) y 7,1% respectivamente(p≤0,001). Las reclusas presentaron combinaciones de diferentes genotiposde VPH (p≤0,011). Las infecciones por Treponema pallidum ocurrieron en 7,1% en reclusas y estuvieron ausentes en las libres. El virus de la hepatitis B, estuvopresente en un 9,5% de reclusas y ausente en mujeres libres (p≤0,040). Losmarcadores para hepatitis C y el virus de la inmunodeficiencia humana (VIH)fueron negativos en ambos grupos; los virus herpes simplex tipo 1 y 2 (VHS) seencontraron en 9,5 % de las reclusas y en 7,1 % de mujeres libres. El consumo de tabaco, alcohol y el uso de otras drogas, mostró una frecuencia de 100%,89,3% y 78,6% respectivamente en mujeres reclusas y un 40%, 30% y 10% en laslibres (p≤0,001). El número de parejas sexuales en relación a la presencia deITS entre ambos grupos, mostró significancia para un número de dos o más parejas(p<0,006). Se observó una elevada prevalencia de ITS únicas o mixtas enmujeres reclusas, así como factores asociados a conductas sexuales de riesgo.


2009 ◽  
Vol 3 (1) ◽  
pp. 27-33
Author(s):  
Tahmina Shirin ◽  
Saidur Rahman ◽  
Fareha Jesmin Rabbi ◽  
Md Humayun Kabir ◽  
KZ Mamun

The prevalence of sexually transmitted diseases (STDs) among patients attending out patients department of Skin and Venereal diseases of Dhaka Medical College Hospital, Dhaka and Shahid Sohrawardy Hospital, Dhaka was studied. A total of 230 patients were enrolled in the study during the period of July, 2006 to May, 2007. Urethral and endocervical swabs were collected from the participants for detection of Neisseria gonorrheae (by culture), Chlamydia trachomatis (by immunochromatoghraphy) and blood samples for the detection of Treponema pallidum antibody (by rapid plasma regain and Treponema pallidum haemagglutination assay), Herpes simplex virus type 2 antibody (both IgM and IgG by enzyme linked immunosorbent assay) and Human Immunodeficiency virus antibody (by enzyme linked immunosorbent assay). Socio-demographic data and data regarding high-risk sexual behavior were also collected. Out of 230 participants, 199 (86.5%) were positive for STDs pathogens studied, among them, 98 (42.6%) were infected with single pathogen and 101 (43.9%) were suffering from multiple infections. The prevalences of N. gonorrheae, C. trachomatis, T. pallidum, and HSV type 2 were 90 (39.1%), 110 (47.8%), 28 (12.2%) and 88 (38.2%) respectively. However, none of them were positive for HIV infection. Use of condom was significantly associated with protection of the participants against STDs. Keywords: Sexually Transmitted Diseases, Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum, Herpes simplex virus type-2, Human Immunodeficiency virus   doi: 10.3329/bjmm.v3i1.2968 Bangladesh J Med Microbiol 2009; 03 (01): 27-33


Author(s):  
Chao Zhang ◽  
Qiang Ren ◽  
Wenhui Chang

Human immunodeficiency virus (HIV)-infected patients are at a higher risk for co-infection with Hepatitis B virus (HBV), Hepatitis C virus (HCV), and Treponema pallidum (TP; the agent causing syphilis) than the general population. The prevalence of HBV, HCV, and syphilis has geographic differences and varies from region to region among HIV-positive individuals. A retrospective study was carried out on HIV-positive individuals between June 2011 and June 2016 in Shaanxi Province. Univariate and multivariate logistic regression analyses using stepwise regression analysis regarding risk factors for HIV–HBV, HIV–HCV, and HIV–syphilis co-infection. HBV–HCV, HCV–syphilis, HBV–syphilis, and HBV–HCV–syphilis co-infection rates were 1.7%, 2.2%, 2.6%, and 0.1%, respectively. The rate of ineffective hepatitis B vaccine immunization was as high as 30.2% among HIV-positive individuals. Ethnicity (OR = 31.030, 95% CI: 11.643–82.694) and HIV transmission routes (OR = 134.024, 95% CI: 14.328–1253.653) were the risk factors for HCV infection in HIV-positive individuals. Among the HIV-positive individuals with the antibodies of TP, the rate of homosexual transmission was also higher, but heterosexual transmission was lower (OR = 0.549 95% CI: 0.382–0.789) The HIV-infected patients in Shaanxi Province had the characteristics of low active detection rate and late diagnosis. The high rate of ineffective vaccination against HBV suggests a need for improved vaccination services.


2008 ◽  
Vol 103 ◽  
pp. S336
Author(s):  
Jenny Smith ◽  
Richard Sterling ◽  
A. Scott Mills ◽  
R. Stravitz ◽  
Velimir Luketic ◽  
...  

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