Scaled P300 Scalp Distribution Correlates of Verbal Deception in an Autobiographical Oddball Paradigm: Control for Task Demand

2003 ◽  
Vol 17 (1) ◽  
pp. 14-22 ◽  
Author(s):  
J. Peter Rosenfeld ◽  
Archana Rao ◽  
Matthew Soskins ◽  
Antoinette Reinhart Miller

Abstract Subjects participated in two trial blocks of an autobiographical oddball paradigm. In the first block, 14% of the stimuli were the subject's phone number, 86% were other, meaningless numbers. Subjects responded yes or no, verbally and truthfully. In the second block, stimuli were dates, and the oddball was the subject's birthdate. Subjects again responded verbally, but dishonestly on about 50% of the trials and truthfully on the other 50%. Reaction times differed between the first and the second blocks, but not between the honest and dishonest trials of the second block. P300 amplitude was reduced in dishonest trials of the second block. Honest trials of both blocks had similar P300 amplitudes. Scaled scalp distributions were the same for honest trials of both blocks, but differed between honest and dishonest trials of the second block. There were no latency effects. The results are discussed from the viewpoint that task demand effects do not mediate the P300 differences between honest and dishonest responses.

2021 ◽  
Vol 12 ◽  
Author(s):  
Kota Suzuki

Sequential congruency effects are observed in interference tasks, in which reaction times (RTs) are shorter for congruent stimuli preceded by congruent (cC) than incongruent stimuli (iC), and RTs are longer for incongruent stimuli preceded by congruent (cI) than incongruent stimuli (iI). These effects are interpreted as resulting from incongruent stimuli triggering attentional control in the next trial, which reduces cognitive control. This study aimed to examine sequential congruency effects on event-related potential (ERP) components for Go- and Nogo-stimuli. We used the hybrid reverse Stroop Go/Nogo task. The stimuli were Kanji characters, “赤” (i.e., red) and “青” (i.e., blue) painted in congruent and incongruent colors. Participants responded to one of the two characters (i.e, the Go-stimulus) and stopped responding to the other character (i.e., the Nogo-stimulus). The results indicated that the Nogo-N1 was reduced by trials preceded by incongruent stimuli compared with congruent ones, suggesting that color processing was inhibited by attentional control; however, there was no reduction in the Go-N1. In addition, the Nogo-N2 amplitudes were larger for cI than iI and iC than cC. On the other hand, the Go-N2 was not modulated by sequential modulation effects, which was lower for incongruent stimuli than congruent stimuli. These results indicate that the Nogo-N2 is involved in cognitive control, whereas the Go-N2 is associated with selection processing. These findings suggest that the modulation of sequential congruency effects of N1 and N2 required the response inhibition task demand; however, Go-P3 and Nogo-P3 amplitudes were the largest for cI. Therefore, the time range of ERP components might be related to the susceptibility of an interaction effect between response inhibition task demand and sequential congruency effects.


2021 ◽  
Vol 11 (4) ◽  
pp. 481
Author(s):  
Damiano Paolicelli ◽  
Alessia Manni ◽  
Antonio Iaffaldano ◽  
Giusy Tancredi ◽  
Katia Ricci ◽  
...  

Cognitive impairment (CI) is a common and disabling symptom of Multiple Sclerosis (MS) with a negative impact on daily living. In this pilot study, we applied magnetoencephalography (MEG) and high density (hd) electroencephalography (EEG) study to evaluate acoustic P300 features in a cohort of early MS. Sixteen MS patients (pwMS) and 19 healthy controls (HCs) matched for age and gender underwent an MEG-/(hd)-EEG-co-recording, using 306-channel Vectorview and 64 scalp electrodes. CI was assessed using Rao’s Brief Repeatable Battery (BRB). Moreover, we performed psychometric tests to assess depression and fatigue. In pwMS, we observed a slight latency prolongation of P300 peak compared to HCs, while P300 amplitude and scalp distribution were similar in the two groups. pwMS did not show an amplitude reduction and different scalp distribution of Event-Related Potentials (ERPs) and Event Related Fields (ERFs) related to an acoustic oddball paradigm. We found an inverse correlation between P300 amplitude and fatigue (r Spearman = −0.4; p = 0.019). In pwMS, phenomena of cortical adaptation to early dysfunction could preserve the cognitive performance of the P300 acoustic task, while the development of fatigue could prospectively lead to amplitude decline of P300, suggesting its possible role as a biomarker.


Cephalalgia ◽  
2004 ◽  
Vol 24 (7) ◽  
pp. 554-563 ◽  
Author(s):  
G Buodo ◽  
D Palomba ◽  
M Sarlo ◽  
C Naccarella ◽  
PA Battistella

Cognitive processing was investigated interictally in 18 children with migraine without aura and 18 age-matched controls by measuring event-related potentials (ERPs) and reaction times (RTs) during an acoustic oddball paradigm. Results showed that N100 amplitude evoked by frequent stimuli was significantly smaller in patients compared with controls. Habituation of target P300 amplitude was observed in patients but not in controls. Mean RTs were equivalent in the two groups, but migraine children made more errors than controls.


2019 ◽  
Vol 4 (6) ◽  
pp. 1482-1488
Author(s):  
Jennifer J. Thistle

Purpose Previous research with children with and without disabilities has demonstrated that visual–perceptual factors can influence the speech of locating a target on an array. Adults without disabilities often facilitate the learning and use of a child's augmentative and alternative communication system. The current research examined how the presence of symbol background color influenced the speed with which adults without disabilities located target line drawings in 2 studies. Method Both studies used a between-subjects design. In the 1st study, 30 adults (ages 18–29 years) located targets in a 16-symbol array. In the 2nd study, 30 adults (ages 18–34 years) located targets in a 60-symbol array. There were 3 conditions in each study: symbol background color, symbol background white with a black border, and symbol background white with a color border. Results In the 1st study, reaction times across groups were not significantly different. In the 2nd study, participants in the symbol background color condition were significantly faster than participants in the other conditions, and participants in the symbol background white with black border were significantly slower than participants in the other conditions. Conclusion Communication partners may benefit from the presence of background color, especially when supporting children using displays with many symbols.


Author(s):  
Melanie C. Steffens ◽  
Inga Plewe

Abstract. The introduction of the Implicit Association Test (IAT; Greenwald, McGhee, & Schwartz, 1998 ) has stimulated numerous research activities. The IAT is supposed to measure the degree of association between concepts. Instances have to be assigned to these concepts by pressing appropriate keys as quickly as possible. The reaction time difference between certain conditions, termed the IAT effect, is used as an indicator of the degree of the concepts’ association. We tested the hypothesis that the degree of association between one concept (or category) and the instances of the other presented concept also influences reaction times. In our experiment, the instances in the target categories, male and female names, were kept constant. The adjectives in the evaluative categories were manipulated: Either the pleasant adjectives were female-associated and the unpleasant adjectives were male-associated, or vice versa. These stereotypic associations were indeed found to exert a substantial influence on the size of the IAT effect. This finding casts doubt on the assumption that the IAT effect may be interpreted as a pure measure of the degree of association between concepts.


2002 ◽  
Vol 16 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Antoinette R. Miller ◽  
J. Peter Rosenfeld ◽  
Matthew Soskins ◽  
Marianne Jhee

Abstract The P300 component of the event-related potential was recorded during two blocks of an autobiographical oddball task. All participants performed honestly during the first block (Phone), i.e., the oddball stimuli were phone numbers. During the second block (Birthday), in which the oddball stimuli were participants' birthdays, a Truth group (N = 13) performed honestly and a Malinger group (N = 14) simulated amnesia. Amnesia simulation significantly reduced P300 amplitudes, both between groups and within the Malinger group (Phone vs. Birthday), possibly because of an increase in task difficulty in the Malinger condition. Analysis of scaled amplitudes also indicated a trend for a feigning-related alteration in P300 topography. Bootstrapping of peak-to-peak amplitudes detected significantly more (93%) Malinger individuals than bootstrapping of baseline-to-peak amplitudes (64%). Bootstrapping also provided evidence of a feigning-related amplitude difference between oddball stimuli (i.e., Phone > Birthday) in 71% of Malinger group individuals. In this comparison, the peak-to-peak measure also performed significantly better in intraindividual diagnostics.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Gyu-Ho Shin ◽  
Sun Hee Park

Abstract Across languages, a passive construction is known to manifest a misalignment between the typical order of event composition (agent-before-theme) and the actual order of arguments in the constructions (theme-before-agent), dubbed non-isomorphic mapping. This study investigates comprehension of a suffixal passive construction in Korean by Mandarin-speaking learners of Korean, focusing on isomorphism and language-specific devices in the passive. We measured learners’ judgment of the acceptability of canonical and scrambled suffixal passives as well as their reaction times (relative to a canonical active transitive). Our analysis generated three major findings. First, learners uniformly preferred the canonical passive to the scrambled passive. Second, as proficiency increased, the judgment gap between the canonical active transitive and the canonical suffixal passive narrowed, but the gap between the canonical active transitive and the scrambled suffixal passive did not. Third, learners (and even native speakers) spent more time in judging the acceptability of the canonical suffixal passive than they did in the other two construction types. Implications of these findings are discussed with respect to the mapping nature involving a passive voice, indicated by language-specific devices (i.e., case-marking and verbal morphology dedicated to Korean passives), in L2 acquisition.


Catalysts ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 552
Author(s):  
Dominika Kozicka ◽  
Paulina Zieleźny ◽  
Karol Erfurt ◽  
Jakub Adamek

Herein we describe the development and optimization of a two-step procedure for the synthesis of N-protected 1-aminomethylphosphonium salts from imides, amides, carbamates, or lactams. Our “step-by-step” methodology involves the transformation of amide-type substrates to the corresponding hydroxymethyl derivatives, followed by the substitution of the hydroxyl group with a phosphonium moiety. The first step of the described synthesis was conducted based on well-known protocols for hydroxymethylation with formaldehyde or paraformaldehyde. In turn, the second (substitution) stage required optimization studies. In general, reactions of amide, carbamate, and lactam derivatives occurred at a temperature of 70 °C in a relatively short time (1 h). On the other hand, N-hydroxymethylimides reacted with triarylphosphonium salts at a much higher temperature (135 °C) and over longer reaction times (as much as 30 h). However, the proposed strategy is very efficient, especially when NaBr is used as a catalyst. Moreover, a simple work-up procedure involving only crystallization afforded good to excellent yields (up to 99%).


2018 ◽  
Author(s):  
Michael J. Morgan ◽  
Joshua A. Solomon

AbstractIt is usually assumed that sensory adaptation is a universal property of human vision. However, in two experiments designed to measure adaptation without bias, we have discovered a minority of participants who were unusual in the extent of their adaptation to motion. One experiment was designed so that targets would be invisible without adaptation; the other, so that adaptation would interfere with target detection. In the first, participants adapted to a spatial array of moving Gabor patches. On each trial the adapting array was followed by a test array in which but all of the test patches except one were identical to their spatially corresponding adaptors; the target moved in the opposite direction to its adaptor. Participants were required to identify the location of the changed target with a mouse click. The ability to do so increased with the number of adapting trials. Neither search speed nor accuracy was affected by an attentionally-demanding conjunction task at the fixation point during adaptation, suggesting low-level (pre-attentive) sites in the visual pathway for the adaptation. However, a minority of participants found the task virtually impossible. In the second experiment the same participants were required to identify the one element in the test array that was slowly moving: reaction times in this case were elevated following adaptation. The putatively weak adapters from the first experiment found this task easier than the strong adapters.


2021 ◽  
Vol 15 ◽  
Author(s):  
Nadine D. Herzog ◽  
Tim P. Steinfath ◽  
Ricardo Tarrasch

Sustained attention is the ability to continually concentrate on task-relevant information, even in the presence of distraction. Understanding the neural mechanisms underlying this ability is critical for comprehending attentional processes as well as neuropsychiatric disorders characterized by attentional deficits, such as attention deficit hyperactivity disorder (ADHD). In this study, we aimed to investigate how trait-like critical oscillations during rest relate to the P300 evoked potential—a biomarker commonly used to assess attentional deficits. We measured long−range temporal correlations (LRTC) in resting-state EEG oscillations as index for criticality of the signal. In addition, the attentional performance of the subjects was assessed as reaction time variability (RTV) in a continuous performance task following an oddball paradigm. P300 amplitude and latencies were obtained from EEG recordings during this task. We found that, after controlling for individual variability in task performance, LRTC were positively associated with P300 amplitudes but not latencies. In line with previous findings, good performance in the sustained attention task was related to higher P300 amplitudes and earlier peak latencies. Unexpectedly, we observed a positive relationship between LRTC in ongoing oscillations during rest and RTV, indicating that greater criticality in brain oscillations during rest relates to worse task performance. In summary, our results show that resting-state neuronal activity, which operates near a critical state, relates to the generation of higher P300 amplitudes. Brain dynamics close to criticality potentially foster a computationally advantageous state which promotes the ability to generate higher event-related potential (ERP) amplitudes.


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