scholarly journals Correlation between fundus autofluorescence and visual function in patients with cone-rod dystrophy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Satoru Kanda ◽  
Takumi Hara ◽  
Ryosuke Fujino ◽  
Keiko Azuma ◽  
Hirotsugu Soga ◽  
...  
Keyword(s):  
Visual Field ◽  
Significant Relationship ◽  
Fundus Autofluorescence ◽  
Univariate Analysis ◽  
Retrospective Chart Review ◽  
Mean Deviation ◽  
Wide Field ◽  
The Mean ◽  
The Relationship ◽  
Field Imaging

AbstractThis study aimed to investigate the relationship between autofluorescence (AF) signal measured with ultra-wide field imaging and visual functions in patients with cone-rod dystrophy (CORD). A retrospective chart review was performed for CORD patients. We performed the visual field test and fundus autofluorescence (FAF) measurement and visualized retinal structures with optical coherence tomography (OCT) on the same day. Using binarised FAF images, we identified a low FAF area ratio (LFAR: low FAF/30°). Relationships between age and logMAR visual acuity (VA), central retinal thickness (CRT), central choroidal thickness (CCT), mean deviation (MD) value, and LFAR were investigated. Thirty-seven eyes of 21 CORD patients (8 men and 13 women) were enrolled. The mean patient age was 49.8 years. LogMAR VA and MD were 0.52 ± 0.47 and − 17.91 ± 10.59 dB, respectively. There was a significant relationship between logMAR VA and MD (p = 0.001). LogMAR VA significantly correlated with CRT (p = 0.006) but not with other parameters. Conversely, univariate analysis suggested a significant relationship between MD and LFAR (p = 0.001). In the multivariate analysis, LFAR was significantly associated with MD (p = 0.002). In conclusion, it is useful to measure the low FAF area in patients with CORD. The AF measurement reflects the visual field deterioration but not VA in CORD.

scholarly journals Widefield imaging of retinal and choroidal tumors

2019 ◽  
Vol 5 (S1) ◽  
Author(s):  
Natalia F. Callaway ◽  
Prithvi Mruthyunjaya
Keyword(s):  
Fundus Autofluorescence ◽  
Imaging Modalities ◽  
Fundus Photography ◽  
Wide Field ◽  
Indocyanine Angiography ◽  
Relationship Of ◽  
The Relationship ◽  
Field Imaging ◽  
Wide Field Imaging ◽  
Sd Oct

Abstract Background Wide-field imaging plays an increasingly important role in ocular oncology clinics. The purpose of this review is to describe the commonly used wide-field imaging devices and review conditions seen in ocular oncology clinic that underwent wide-field imaging as part of the multimodal evaluation. Summary of review Wide-field or wide-angle imaging is defined as greater than 50° field of view. Modern devices can reach far beyond this reporting fields of view up to 267°, when utilizing montage features, with increasingly impressive resolution. Wide-field imaging modalities include fundus photography, fluorescein angiography (FA), fundus autofluorescence (FAF), indocyanine angiography (ICG), spectral domain optical coherence tomography (SD-OCT), and recently wide-field OCT Angiography (OCTA). These imaging modalities are increasingly prevalent in practice. The wide-field systems include laser, optical, and lens based systems that are contact or non-contact lens systems each with its own benefits and drawbacks. The purpose of this review is to discuss commonly used wide-field imaging modalities for retinal and choroidal tumors and demonstrate the use of various widefield imaging modalities in select ocular oncology cases. Conclusions Clinical examination remains the gold standard for the evaluation of choroidal and retinal tumors. Wide-field imaging plays an important role in ocular oncology for initial documentation, surgical planning, determining the relationship of the tumor to adjacent ocular structures, following tumor size after treatment, and monitoring for recurrence.

Relationship between mean follow-up intraocular pressure, rates of visual field progression and current target intraocular pressure guidelines

2020 ◽  
pp. bjophthalmol-2020-317406
Author(s):  
Bruna Melchior ◽  
Carlos Gustavo De Moraes ◽  
Jayter S Paula ◽  
George A Cioffi ◽  
Christopher A Girkin ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Visual Field ◽  
Treatment Guidelines ◽  
Evaluation Study ◽  
Mean Deviation ◽  
Racial Groups ◽  
Current Guideline ◽  
Registration Number ◽  
The Mean

AimsTo investigate if eyes presenting intraocular pressure (IOP) within the limits of current guideline-driven target IOP indeed experience slow rates of glaucomatous visual field (VF) progression.MethodsA total of 8598 24-2 VF tests from 603 eyes from the African Descent and Glaucoma Evaluation Study with manifest glaucoma were included. The sample was split into three groups based on baseline VF mean deviation (MD): G1 (better than −5.0 dB), G2 (−5.0 to −10 dB) and G3 (worse than −10 dB). We investigated the relationship between existing target IOP guidelines and rates of MD progression in these groups.ResultsFor stable eyes, the medians and IQR of the mean follow-up IOP were G1=15.0 mmHg (IQR: 13.1 to 17.7), G2=13.2 mmHg (IQR: 11.6 to 14.3) and G3=11.9 mmHg (IQR: 10.1 to 13.8) (p<0.01). When considering the mean follow-up IOP within the limits proposed by current guidelines, the median MD slopes were: −0.20 dB/y (IQR: −0.43 to −0.02) for G1<21 mmHg, −0.19 dB/y (IQR: −0.51 to −0.01) for G2<18 mmHg and −0.15 dB/y (IQR: −0.47 to 0.05) for G3<15 mmHg (p=0.63). There were no significant differences between racial groups.ConclusionIn a sample of patients with manifest glaucoma, despite substantial variability between eyes, adherence to treatment guidelines helped slow the rates of global VF progression at various stages of disease.Trial registration numberclinicaltrials.gov Identifier: NCT00221923.

scholarly journals Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Pierre-Maxime Lévêque ◽  
Pierre Zéboulon ◽  
Emmanuelle Brasnu ◽  
Christophe Baudouin ◽  
Antoine Labbé
Keyword(s):  
Visual Field ◽  
Univariate Analysis ◽  
Normal Subjects ◽  
Vessel Density ◽  
Spectral Domain ◽  
Control Group ◽  
Mean Deviation ◽  
Ganglion Cell Complex ◽  
Fiber Layer ◽  
Spectral Domain Oct

Purpose. To detect changes in optic nerve head (ONH) vascularization in glaucoma patients using spectral-domain OCT angiography (OCT-A).Material and Method. Fifty glaucoma patients and 30 normal subjects were evaluated with OCT-A (AngioVue®, Optovue). The total ONH vessel density and temporal disc vessel density were measured. Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded for glaucoma patients. Correlations among total and temporal ONH vessel density and structural and VF parameters were analyzed.Results. In the glaucoma group, total and temporal ONH vessel density were reduced by 24.7% (0.412 versus 0.547;p<0.0001) and 22.88% (0.364 versus 0.472;p=0.001), respectively, as compared with the control group. Univariate analysis showed significant correlation between rim area (mm2) and temporal ONH vessel density (r=0.623;p<0.0001) and total ONH vessel density (r=0.609;p<0.0001). Significant correlations were found between temporal and total ONH vessel density and RNFL, GCC, VF mean deviation, and visual field index.Conclusion. In glaucoma patients OCT-A might detect reduced ONH blood vessel density that is associated with structural and functional glaucomatous damage. OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.

scholarly journals Hubungan Antara Paritas Dan Partus Lama Dengan Kejadian Asfiksia Neonatorum Pada Bayi Baru Lahir Di Rumah Sakit Umum Daerah Kota Prabumulih Tahun 2019

2020 ◽  
Vol 5 (2) ◽  
pp. 101-106
Author(s):  
Dwi Saputri Mayang Sari
Keyword(s):  
High Risk ◽  
General Hospital ◽  
Significant Relationship ◽  
Univariate Analysis ◽  
Bivariate Analysis ◽  
P Value ◽  
Cross Sectional ◽  
Asphyxia Neonatorum ◽  
Prolonged Labor ◽  
The Relationship

Asphyxia Neonatorum is a failure to start and continue breathing spontaneously and regularly when a new baby is born or some time after birth. Babies may be born in asphyxia or may be able to breathe but then experience asphyxia some time after birth. The purpose of this study was to determine the relationship between parity and old parturition with the incidence of asphyxia neonatorum in the pre-Sumatran city general hospital in 2019. This study uses an Analytical Survey using a Cross Sectional approach. The population of this research is the babies born in the prehumulih city general hospital in 2019 amounted to 1763 people. The number of samples in this study were 326 respondents. In the univariate analysis it was found that from 326 respondents it was found that parity of high risk mothers was 168 respondents (51.5%) while parity of low risk mothers was 158 respondents (48.5%) and mothers who were diagnosed with prolonged labor were 149 respondents (45.7 %) while mothers who were not diagnosed with prolonged labor were 177 respondents (54.3%). Bivariate analysis shows parity has a significant relationship with the incidence of asphyxia neonatorum (p value 0,000) and old parturition has a significant relationship with the incidence of asphyxia neonatorum (p value 0,000). The conclusion of this study is that there is a relationship between parity and old parturition with the incidence of asphyxia neonatorum.

scholarly journals The Efficacy of Core Stability Assessment as a Determiner of Performance in Dynamic Balance and Agility Tests.

2016 ◽  
Author(s):  
Kieran McCartney ◽  
Jacky Forsyth
Keyword(s):  
Significant Relationship ◽  
Dynamic Balance ◽  
Core Stability ◽  
Stability Assessment ◽  
Stability Tests ◽  
Active Population ◽  
The Mean ◽  
Physiological Tests ◽  
The Relationship ◽  
Flexion Test

Aim: The aim of this study was to investigate if tests used to assess core stability could be used to determine success in physiological tests applied to assess dynamic balance and agility for a young active population. Methods: Pearson's r correlation coefficient was used to assess the relationship between the core stability tests and the dynamic balance and agility tests. Evaluation of the tests was established using Cronbach's coefficient of variance as part of intra-rater reliability tests. An analysis of 18 active college aged students was conducted (males: n= 13, females: n= 5). The mean &plusmn; SD age for males was 19.2 years &plusmn; 3.22 years and for females was 19.4 years &plusmn; 1.14 years. Conclusion: The results indicate that there is no significant relationship between tests that assess core stability and tests conducted to assess dynamic balance in active young adults. With the exception of the abdominal flexion test, no significant relationship exists between the remaining core stability tests and agility T-Test. Core stability is not a determinant of balance and agility.

scholarly journals Classification and Statistical Trend Analysis in Detecting Glaucomatous Visual Field Progression

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Cristiana Valente ◽  
Elisa D’Alessandro ◽  
Michele Iester
Keyword(s):  
Statistical Analysis ◽  
Standard Deviation ◽  
Visual Field ◽  
Trend Analysis ◽  
Open Angle Glaucoma ◽  
Mean Deviation ◽  
Threshold Strategy ◽  
Visual Field Progression ◽  
The Mean

Aim. To evaluate the agreement between different methods in detection of glaucomatous visual field progression using two classification-based methods and four statistical approaches based on trend analysis. Methods. This is a retrospective and longitudinal study. Twenty Caucasian patients (mean age 73.8 ± 13.43 years) with open-angle glaucoma were recruited in the study. Each visual field was assessed by Humphrey Field Analyzer, program SITA standard 30-2 or 24-2 (Carl Zeiss Meditec, Inc., Dublin, CA). Full threshold strategy was also accepted for baseline tests. Progression was analyzed by using Hodapp–Parrish–Anderson classification and the Advanced Glaucoma Intervention Study visual field defect score. For the statistical analysis, linear regression (r2) was calculated for mean deviation (MD), pattern standard deviation (PSD), and visual field index (VFI), and when it was significant, each series of visual field was considered progressive. We also used Progressor to look for a significant progression of each visual field series. The agreement between methods, based on statistical analysis and classification, was evaluated using a weighted kappa statistic. Results. Thirty-eight visual field series were analyzed. The mean follow-up time was 6.2 ± 1.53 years (mean ± standard deviation). At baseline, the mean MD was −7.34 ± 7.18 dB; at the end of the follow-up, the mean MD was −9.25 ± 8.65 dB; this difference was statistically significant (p<0.001). The agreement to detect progression was fair between all methods based on statistical analysis and classification except for PSD r2. A substantial agreement (κ = 0.698 ± 0.126) was found between MD r2 and VFI r2. With the use of all the statistical analysis, there was a better time-saving. Conclusions. The best agreement to detect progression was found between MD r2 and VFI r2. VFI r2 showed the best agreement with all the other methods. GPA2 can help ophthalmologists to detect glaucoma progression and to help in treatment decisions. PSD r2 was the worse method to detect progression.

Size of the Visual Field in Collegiate Fast-Pitch Softball Players and Nonathletes

1995 ◽  
Vol 81 (3_suppl) ◽  
pp. 1307-1312 ◽  
Author(s):  
William P. Berg ◽  
Suzanne M. Killian
Keyword(s):  
Visual Field ◽  
Undergraduate Students ◽  
Division I ◽  
Field Size ◽  
Female College Students ◽  
Kinetic Perimetry ◽  
Skill Test ◽  
Batting Performance ◽  
The Mean ◽  
The Relationship

The purpose of this study was to examine whether visual-field size differed between female Division I collegiate fast-pitch Softball players and female college students who were nonathletes. The relationship between visual-field size and batting performance among the softball players was also examined. 24 female undergraduate students (12 varsity fast-pitch softball players and 12 nonathletes) participated. The size of the visual field was measured via manual kinetic perimetry, and batting performance was assessed using a batting-skill test as well as batting averages for an entire competitive season. Analyses indicated that the mean visual-field size of softball players was significantly larger than that of nonathletes. However, there was no relationship between visual-field size and batting performance among the softball players. Results are discussed with respect to the origin of the superiority of visual-field size of softball players.

scholarly journals The Relationship between Demographic Factors in Adult Patients with Stroke

2020 ◽  
Vol 7 (4) ◽  
pp. 14
Author(s):  
Samad Shams-Vahdati ◽  
Alireza Ala ◽  
Eliar Sadeghi-Hokmabad ◽  
Neda Parnianfard ◽  
Nasim Ahmadi Sepehri ◽  
...  
Keyword(s):  
Significant Relationship ◽  
Demographic Data ◽  
Demographic Factors ◽  
Patient Characteristics ◽  
Developed Countries ◽  
Adult Patients ◽  
Stroke Severity ◽  
Statistical Population ◽  
The Mean ◽  
The Relationship

Background: Developing countries are challenging with stroke as the third cause of death in developed countries and the most popular neurologic disease which results in disability. This study was designed to assess the relationship between demographic factors and early outcome in adult patients with difference type of stroke. Methods and Materials: A retrospective register review was performed from March 2017 to March 2018. ED medical document (chart) were reviewed by a neurologist or physician to obtain the clinical diagnosis, patient characteristics. Their demographic data (such as age, gender), NIHSS score and MRS score were filled in questionnaire. the significant variables were verified in a multivariable model to achieve an attuned estimate of effect. Results: A total of 861 patients with stroke were included in the analysis; the male and female sex in the statistical population were 56% and 43%; the mean age of the patients was 14.32 ± 61.74. The mean NIHSS (16.08±10.51) & MRS (3.66) scores were evaluated, respectively 47% severe stroke (NICHSS>16). There was no significant relationship between age increase and NIHSS increase (P = 0.86). Conclusion: Aging has a significant relationship with increased stroke. Gender and age differences in risk of stroke outcomes are mostly described by variations in physical characteristics and stroke severity of the patients.

scholarly journals Multivariate methods to track the spatiotemporal profile of feature-based attentional selection using EEG

2019 ◽  
Author(s):  
Johannes Jacobus Fahrenfort
Keyword(s):  
Visual Field ◽  
Time Series Data ◽  
Univariate Analysis ◽  
Attentional Selection ◽  
Series Data ◽  
Attentional Processes ◽  
Eeg Data ◽  
Feature Based ◽  
Multivariate Pattern ◽  
The Relationship

This chapter provides a tutorial-style guide to analyzing electroencephalogram (EEG) data contingent on feature-based attentional selection. It is targeted at researchers that currently investigate attentional processes using univariate methods but consider moving to multivariate analyses. The chapter starts by providing examples of classical univariate analysis, in which the EEG signal occurring ipsilateral to the target is subtracted from the signal that occurs in a contralateral electrode (i.e. the classical N2pc, an interhemispheric posterior negativity emerging around 180–200 ms). Next, it shows how the same type of information can also be identified using multivariate pattern analysis (MVPA). MVPA does not restrict one to contrast attentional selection in opposite hemifields, but also allows one to assess attentional selection on the vertical meridian, or even within a quadrant of the visual field, opening up new avenues for research. The chapter demonstrates how to visualize topographic maps of attentional selection when using MVPA, and shows how to assess timing onsets using the percent-amplitude latency method. Finally, it shows how a forward encoding model enables one to characterize the relationship between a continuous experimental variable (such as attended targets positioned on a circle) and EEG activity. This allows one to construct brain patterns for positions in the visual field that were never attended in the data that was used to generate the forward model. This chapter is intended as a practical guide, explaining the methods and providing the scripts that can be used to generate the figures in-line, thus providing a step-by-step cookbook for analyzing neural time series data in the field of feature-based attentional selection.

scholarly journals The Relationship Between Defense Mechanisms and Nurses’ Occupational Burnout: A Cross-Sectional Study

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Forouzan Elyasi ◽  
Seyed Mohammad Hosseininejad ◽  
Parisa Islami Parkoohi ◽  
Mahsa Kamali ◽  
Marzieh Azizi ◽  
...  
Keyword(s):  
Significant Relationship ◽  
Defense Mechanisms ◽  
Maslach Burnout Inventory ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Occupational Burnout ◽  
Cross Sectional ◽  
Low Level ◽  
The Mean ◽  
The Relationship

Background: Occupational burnout is a psychological syndrome that occurs in response to chronic stress in the workplace. Nowadays, it is known as one of the most important consequences of occupational stress. Defense mechanisms may also affect occupational burnout. Objectives: Since burnout is an important factor influencing the productivity of nurses, this study was conducted to investigate the relationship between the defense mechanisms and occupational burnout among nurses in the educational hospitals of an urban area in Iran. Methods: This descriptive cross-sectional study was conducted on 318 nurses who had at least one-year of work experience in four educational hospitals in Sari city, Iran, in 2018. Sampling was performed using the proportional stratified sampling method. The data were collected by the Maslach Burnout Inventory (MBI) scale, psychological Defense Styles questionnaire (DSQ-40), and a demographic questionnaire. Data were analyzed using descriptive and inferential statistics via the SPSS software V.20. Results: A total of 318 nurses were studied, 13 (4.1%) of the nurses had a burnout. The mean score of the dimension of emotional exhaustion (EE) was 17.49, in the dimension of depersonalization (DP) it was 5.42, and in the dimension of personal achievement (PA) it was 31.58. They indicated a low level of occupational burnout, and the mean scores of FE, DP, and PA subscales indicated a low level of occupational burnout. The use of more mature defense mechanisms had a significant negative correlation with the increase of the EE score (rho = -0.210, P < 0.001), but no significant relationship was reported with other aspects of burnout. Increased use of immature defense mechanisms had a direct correlation with the increase in the score of DP (rho = 0.255 and P < 0.001), but had a significant inverse relationship with the PA score (rho = -0.238 and P < 0.001) and no significant relationship with EE (P = 0.627). No significant relationship was found between the use of neurotic defense mechanisms and burnout dimensions (PEE = 0.119, PDP = 0.174, and PPA = 0.127). Conclusions: Since there is a significant relationship between defense mechanisms and occupational burnout, using the components of defense mechanisms in job interviews can lead to choosing appropriate nurses to perform different tasks in different settings, in accordance with individual and psychological characteristics. Also, teaching problem-solving skills, stress management, and useful information can improve defense mechanisms, nurses’ job performance, and patient satisfaction.

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