scholarly journals Frailty transitions and cognitive function among South Korean older adults

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Fatima Nari ◽  
Bich Na Jang ◽  
Hin Moi Youn ◽  
Wonjeong Jeong ◽  
Sung-In Jang ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Daily Living ◽  
Mini Mental State Examination ◽  
Adult Population ◽  
Geriatric Syndrome ◽  
South Korean ◽  
Adl Disability ◽  
Older Adult Population ◽  
State Examination

AbstractFrailty is considered a multidimensional geriatric syndrome, manifested by the accumulation of age-associated deficits. The consequences of frailty transitions are still understudied. This study evaluated the influence of frailty transitions on cognitive function in the older adult population. We used data derived from the Korean Longitudinal Study of Aging (KLoSA) (2008–2018) on older adults aged ≥ 65 years. Frailty was assessed using a validated Korean frailty measure known as the frailty instrument (FI), and cognitive function was measured using the Korean version of the Mini-Mental State Examination (K-MMSE). Transitions in frailty and their relationship with cognitive function were investigated using lagged generalized estimating equations (GEE), t-tests, and ANOVA. Respondents who experienced frailty transitions (those with ameliorating frailty), those who developed frailty, and whose frailty remained constant, were more likely to have a lower cognitive function than those who were consistently non-frail. Older age, activities of daily living (ADL) disability, and instrumental ADL disability were more negatively associated with declining cognitive function, especially in the “frail → frail” group. Changes in all individual components of the frailty instrument were significantly associated with impaired cognitive function. The results suggest an association between frailty transitions and cognitive impairment. Over a 2-year span, the remaining frail individuals had the highest rate of cognitive decline in men, while the change from non-frail to frail state in women was significantly associated with the lowest cognitive function values. We recommend early interventions and prevention strategies in older adults to help ameliorate or slow down both frailty and cognitive function decline.

scholarly journals Association between the Use of Proton Pump Inhibitors and Cognitive Impairment in Older Adults

2018 ◽  
Vol 60 (1) ◽  
Author(s):  
Camilo Gómez ◽  
Miguel German Borda Borda ◽  
Mario Ulises Pérez ◽  
Pamela Tella Vega ◽  
Carlos Alberto Cano Gutiérrez
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Adult Population ◽  
Cross Sectional ◽  
Adjusted Risk ◽  
Risk Increase ◽  
Older Adult Population ◽  
State Examination

Objective: The objective was to describe the association between the presence of cognitive impairment and the use of proton pump inhibitors (PPI) in the older adult population in Bogotá, Colombia. Methods: We analyzed the SABE Bogotá study. This study included 2,000 people over 60 years, in a cross-sectional sample. The variable of interest was the alteration in the modified Mini-Mental State Examination (MMSE-M). It was related to the use of PPI. This analysis was adjusted for factors such as sex, age, years of schooling and marital status. Results: The average age was 71.17±8.05 years, 63.4% were women. We found that 20.7% used PPIs, with an average duration of use of 74.8±93.76 months. 12.6% of older adults had altered MMSE-M, with a higher prevalence in PPI users (25.4% vs. 20.02%; p: 0.049). In the multivariate analysis, an association of adjusted risk increase was found between cognitive impairment and the use of PPIs for ≥24 months (OR: 1.90; CI: 1.11-3.24; p = 0.018). Conclusions: This study shows an association of a significant increase in the risk between using PPIs for ≥ 24 months and developing cognitive impairment. More studies are needed to conclude a direct causality relationship.

scholarly journals Association between cognitive declines and disability in activities of daily living in older adults with COPD: evidence from the China health and retirement longitudinal study

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e040098
Author(s):  
Bingyan Gong ◽  
Shaomei Shang ◽  
Chao Wu
Keyword(s):  
Older Adults ◽  
Regression Analysis ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Visuospatial Ability ◽  
Cross Sectional ◽  
Adl Disability

ObjectivesThis study aimed to investigate the relationship between disability and domain-specific cognitive function in older adults with chronic obstructive pulmonary disease (COPD).DesignCross-sectional analyses combined with retrospective longitudinal analyses.SettingWe included 450 communities in China.ParticipantsIn this study, 1022 (mean age: 68.6±6.3; 612 males) and 152 (mean age: 67.0±5.2; 83 males) older adults with COPD from the China Health and Retirement Longitudinal Study were included in a cross-sectional multivariate linear regression analysis and a longitudinal logistic regression analysis, respectively.Outcome measuresDisability was determined by the difficulty or inability to complete 1 of the 12 activity items in basic activities of daily living (ADL) and instrumental ADL. The cognitive dimensions of episodic memory, attention/numerical ability, orientation to time, and visuospatial ability were assessed via the immediate/delayed recall task, serial sevens task, naming the current date and pentagon-figure-drawing tasks, respectively.ResultsOf 1022 older respondents with COPD at wave-4, 48.5% had ADL disability. Declines in the global cognitive function (β (95% CI)=−0.627 (−1.214 to –0.040)), orientation to time (β (95% CI)=−0.207 (−0.364 to –0.050)) and visuospatial ability (β (95% CI)=−0.068 (−0.127 to –0.009)) were significantly associated with the presence of ADL disability, when demographic and health-related variables were adjusted. Of 152 older participants with COPD and without ADL disability in wave-2, 61 (40.1 %) developed disability over a 2-year follow-up. Relative to the participants without a decline in orientation to tine, those with the condition had greater odds of incidence of ADL disability increased by a factor of about 1.46 over a 2-year follow-up.ConclusionsIn older adults with COPD, orientation to time and visuospatial inability are vulnerable to the presence of a disability. Prevention of a decline in orientation to time might help prevent disability in older people with COPD.

scholarly journals Effects of dance on the postural balance, cognition and functional autonomy of older adults

2018 ◽  
Vol 71 (suppl 5) ◽  
pp. 2302-2309 ◽  
Author(s):  
Eliane Gomes da Silva Borges ◽  
Rodrigo Gomes de Souza Vale ◽  
Carlos Soares Pernambuco ◽  
Samaria Ali Cader ◽  
Selma Pedra Chaves Sá ◽  
...  
Keyword(s):  
Older Adults ◽  
Activities Of Daily Living ◽  
Mental State ◽  
Postural Balance ◽  
Daily Living ◽  
Mini Mental State Examination ◽  
Control Group ◽  
Ballroom Dancing ◽  
Functional Autonomy ◽  
State Examination

ABSTRACT Objective: to evaluate the postural balance, cognition and functional autonomy of older adults with dementia, who are long-stay inpatients, subjected to ballroom dancing. Method: simple randomized clinical study. Older adult sample: control group (30) and experimental group (30). The groups were subjected to the protocol of functional autonomy for activities of daily living; to the assessment of cognition (mini-mental state examination); and to the analysis of postural balance (stabilometric and postural platforms). The analysis of variance with repeated measures for group and time factors, and Scheffé’s post hoc test were used, with significance of p < 0.05. Results: For the mini-mental state examination, the control group presented a 24.27 mean, and the experimental 22.75. Functional autonomy for activities of daily living – experimental: 54.47 ± 7.24 (p < 0.0001) x control: 61.77 ± 8.47 (p = 0.011). Postural balance – experimental: X = 3.16 ± 3.44 (p = 0.02) x control = X = 6.30 ± 7.62 (p = 0.04). Conclusion: Ballroom dancing can be recommended for older adults to provide improvement in their balance and motor performance of the activities of daily living.

scholarly journals APTIDÃO CARDIORRESPIRATÓRIA E FUNÇÃO COGNITIVA EM IDOSOS

2011 ◽  
Vol 16 (1) ◽  
Author(s):  
Diana Dos Santos ◽  
Adriana C A Guimarães ◽  
André Junqueira Xavier ◽  
Fernanda Guidarini Monte ◽  
Silvia Rosane Parcias
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Cardiorespiratory Fitness ◽  
Clinical Characteristics ◽  
Mini Mental State Examination ◽  
Economic Level ◽  
Physical Exercises ◽  
Proportional Relation ◽  
Social Demographic ◽  
State Examination

A aptidão cardiorrespiratória parece estar positivamente relacionada ao desempenho cognitivo. Nesse sentido, o objetivo do estudo foi analisar a relação entre a aptidão cardiorrespiratória e a função cognitiva em indivíduos idosos. Participaram deste estudo 90 idosos com média de idade de 69,3±3,5 anos, inseridos nos programas de exercícios físicos da UDESC e do CATI da Grande Florianópolis, no ano de 2009. Foram utilizados: entrevista semiestruturada para identificar as características sociodemográficas e clínicas; questionário Miniexame do Estado Mental para avaliar a função cognitiva e Teste de Caminhada de uma Milha, para classificar a amostra quanto à capacidade cardiorrespiratória. Os valores do teste de caminhada foram estratificados em três grupos de aptidão física: abaixo da média, na média e acima da média, para a idade. Foram realizadas análises estatísticas descritivas e inferenciais. Verificaram-se diferenças estatisticamente significantes (p<0,05) entre os três grupos da aptidão cardiorrespiratória quanto ao sexo, à escolaridade e à renda. Observou-se tendência maior de declínio cognitivo em idosos com aptidão cardiorrespiratória abaixo da média. O estudo sugere existir uma relação diretamente proporcional entre a capacidade cardiorrespiratória e a função cognitiva em indivíduos idosos. CARDIORESPIRATORY FITNESS AND COGNITIVE FUNCTION IN OLDERS ADULTS abstract The cardiorespiratory fitness seems to be positively related to the cognitive function. The objective of this study was to analyze the relation between the cardiorespiratory fitness and the cognitive function in older adults. Ninety individuals, participants of programs of physical exercises, with average of age of 69,3±3,5 years, had been selected. Semi-structures interviews had been applied to identify social, demographic and clinical characteristics. The “Mini-mental state examination” had been applied to evaluate the cognitive function and Walked Test of a Mile had been used to classify the cardiorespiratory fitness. The walked test values had been divided in three groups of cardiorespiratory fitness: below the average; in the average and above the average, for the age. Its statistical analyses descriptive and inferential had been used. Significant statistical differences (p<0,05) had been founded when comparing the cardiorespiratory fitness with the sex, years of study and economic level. Bigger trend of cognitive decline was observed when the cardiorespiratory fitness was below the average. This study suggests that exist a directly proportional relation between the cardiorespiratory fitness and the cognitive function in older adults.

scholarly journals Association between adiposity levels and cognitive impairment in the Chilean older adult population

2019 ◽  
Vol 8 ◽  
Author(s):  
Y. Concha-Cisternas ◽  
F. Lanuza ◽  
H. Waddell ◽  
Anne Sillars ◽  
A. M. Leiva ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mini Mental State Examination ◽  
Adult Population ◽  
Cross Sectional Study ◽  
National Health Survey ◽  
Sectional Study ◽  
Cross Sectional ◽  
Confounding Variables ◽  
Older Adult Population ◽  
State Examination

AbstractAlthough both obesity and ageing are risk factors for cognitive impairment, there is no evidence in Chile on how obesity levels are associated with cognitive function. Therefore, the aim of the present study was to investigate the association between adiposity levels and cognitive impairment in older Chilean adults. This cross-sectional study includes 1384 participants, over 60 years of age, from the Chilean National Health Survey 2009–2010. Cognitive impairment was evaluated using the Mini-Mental State Examination. BMI and waist circumference (WC) were used as measures of adiposity. Compared with people with a normal BMI, the odds of cognitive impairment were higher in participants who were underweight (OR 4·44; 95 % CI 2·43, 6·45; P &lt; 0·0001), overweight (OR 1·86; 95 % CI 1·06, 2·66; P = 0·031) and obese (OR 2·26; 95 % CI 1·31, 3·21; P = 0·003). The associations were robust after adjustment for confounding variables. Similar results were observed for WC. Low and high levels of adiposity are associated with an increased likelihood of cognitive impairment in older adults in Chile.

scholarly journals No clear relationship between antihypertensive class and cognitive function over 12 months in a cohort study of community-dwelling adults aged 80 and over

2019 ◽  
Vol 10 ◽  
pp. 204062231882084 ◽  
Author(s):  
Ruth Peters
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Adult Population ◽  
Community Dwelling ◽  
Channel Blockers ◽  
80 And Over ◽  
Aged 80 And Over ◽  
Increased Risk ◽  
Older Adult Population ◽  
The Impact

Background: Hypertension is prevalent in older adults. Hypertension has also been associated with an increased risk of cognitive decline. However, evidence relating to the impact of antihypertensive use is mixed. Calcium-channel blockers (CCB) have been suggested as the most beneficial class of antihypertensive for protection of cognition in older adults, however, to date, there have been no cohort studies designed to examine this. Methods: Community-dwelling treated hypertensive adults aged 80 and over were recruited from general practice sites and followed for 1 year. Cognitive function was assessed at baseline and 12 months using the modified Mini-Mental State Exam (3MS). Regression was used to examine the association between 12-month exposure to antihypertensive class and change in cognitive function. Results: A total of 292 participants completed the study. Mean change in 3MS score was a rise of 0.53 [standard deviation (SD) 4.7] 3MS points in those taking CCBs ( n = 135) compared with a drop of 0.09 (SD 5.1) in those without ( n = 157) p = 0.28. There was no relationship between CCBs or between any antihypertensive class and change in cognitive function over 1 year. Additional analyses using a clinically meaningful fall of 5 or more 3MS points showed similar results. Conclusion: In a hypertensive community-dwelling older adult population treated with antihypertensives, there was no evidence that CCBs were protective of cognitive function over a 12-month exposure. If a protective effect is present, it may be small or require a longer treatment period. Larger longer studies are required for confirmation.

Factors Associated With Adherence to an Accelerometer Protocol in Older Adults

2011 ◽  
Vol 8 (8) ◽  
pp. 1152-1159 ◽  
Author(s):  
Erin Gemmill ◽  
Constance M. Bayles ◽  
Kathleen McTigue ◽  
William Satariano ◽  
Ravi Sharma ◽  
...  
Keyword(s):  
Older Adults ◽  
Daily Living ◽  
Mini Mental State Examination ◽  
Multivariate Model ◽  
Lower Body ◽  
Aging Effects ◽  
Factors Associated ◽  
The Mean ◽  
State Examination ◽  
Predictors Of Adherence

Background:Adherence to protocols of accelerometer use by participants of research studies is crucial to ensure the most accurate measure of their physical activity.Methods:We used data from a study of 201 individuals 65 years of age and older to examine whether aging effects on physical and cognitive health limit the ability of an older adult to be adherent to an accelerometer protocol.Results:A comparison of participants who met the adherent person criteria with those who did not showed that the percentage of participants whose income is $20,000 or greater, the percentage of participants who reported white race, and the mean number of school grades completed were significantly different between the 2 groups. Logistic regression analyses showed that the best multivariate model to predict being a valid person included Instrumental Activities of Daily Living score, while the best multivariate model to predict being an adherent person included Modified Guralnik Lower Body Score and Mini-Mental State Examination Score.Conclusions:This study found that certain measures of physical and cognitive functioning were the best predictors of adherence to an accelerometer protocol among older adults.

scholarly journals Study of cognitive functions in major idiopathic interstitial pneumonias

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Mohamed W. Zakaria ◽  
Reem I. El-Korashy ◽  
Mostafa O. Shaheen ◽  
Samah Selim ◽  
Kwashi J. Amum
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Cognitive Dysfunction ◽  
Mini Mental State Examination ◽  
Mmse Score ◽  
Control Group ◽  
Healthy Individuals ◽  
Co Morbidity ◽  
Impaired Lung Function ◽  
State Examination

Abstract Background Cognitive dysfunction in idiopathic interstitial pneumonia (IIP) is an important clinical co-morbidity that is associated with impaired lung function. The aim of the work is to assess cognitive function in major IIP and to find out the relation between cognitive dysfunction and the oxygenation parameters. Results Fifty individuals were involved in the study; 30 patients with major IIP and 20 healthy individuals. Patients with IIP had significantly lower mini mental state examination (MMSE) score compared to the control group (P < 0.001). Wechsler Deterioration Index (WDI) revealed that 33.3% (n = 10) of the patients with IIP had sure cognitive impairment and 26.6% (n = 8) had ongoing cognitive deterioration. Patients with idiopathic pulmonary fibrosis (IPF) had lower cognitive function than other IIP. Conclusion There is an impairment of cognitive function in patients with major IIP, particularly in IPF, as measured by WDI and MMSE. Further large studies are needed to assess the possible predictors of cognitive impairment and their effects on the patients’ outcome.

scholarly journals Vision and Hearing Impairments Affecting Activities of Daily Living among Malaysian Older Adults by Gender

2021 ◽  
Vol 18 (12) ◽  
pp. 6271
Author(s):  
Yee Mang Chan ◽  
Norhafizah Sahril ◽  
Ying Ying Chan ◽  
Nor’ Ain Ab Wahab ◽  
Norliza Shamsuddin ◽  
...  
Keyword(s):  
Older Adults ◽  
Gender Differences ◽  
Activities Of Daily Living ◽  
Hearing Impairment ◽  
Daily Living ◽  
Hearing Impairments ◽  
Cross Sectional ◽  
Middle Income ◽  
Middle Income Countries ◽  
Adl Disability

Vision and hearing impairments are common among older adults and can cause undesirable health effects. There are limited studies from low- and middle-income countries exploring gender differences between vision and hearing impairment with Activities of Daily Living (ADL) disability. Therefore, this study aimed to investigate gender differences between vision and hearing impairments with ADL disability among older adults in Malaysia. Cross-sectional data from 3977 respondents aged 60 and above from the Malaysian National Health and Morbidity Survey 2018 were used. We used logistic regression analysis to measure associations between vision and hearing impairments with ADL disability, adjusted for covariates. The prevalence of ADL disability was higher among females than males (p < 0.001). The adjusted associations between vision impairment and ADL disability were significant among males (aOR 3.79; 95%CI 2.26, 6.38) and females (aOR 2.66; 95%CI 1.36, 5.21). Similarly, significant adjusted associations were found between hearing impairment and ADL disability among males (aOR 5.76; 95%CI 3.52, 9.40) and females (aOR 3.30; 95%CI 1.17, 9.33). Vision and hearing impairments were significantly associated with ADL disability, with no gender differences identified. Early detection and effective management of vision and hearing impairments are important to prevent ADL disability and improve older adults’ level of independence.

The Brief Odor Detection Test (B-ODT) for Very Early Diagnosis of Cognitive Decline: A Preliminary Study

2017 ◽  
Vol 18 (2) ◽  
pp. 197-210
Author(s):  
Dimitra Savvoulidou ◽  
Efthymia Totikidou ◽  
Chariklia Varvesiotou ◽  
Magda Iakovidou ◽  
Ourania Sfakianaki ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Adult Population ◽  
Detection Threshold ◽  
Community Dwelling ◽  
Odor Detection ◽  
Olfactory Impairment ◽  
Older Adult Population ◽  
Community Dwelling Older Adults

Olfactory impairment in older adults is associated with cognitive decline. This study describes the development of a Brief Odor Detection Test (B-ODT), and its pilot administration in community-dwelling older adults. The study aimed at examining whether the test could differentiate older adults with very mild cognitive impairment from their cognitively healthy counterparts. The sample consisted of 34 older adults (22 women), aged from 65 to 87 years. Participants were divided into two groups according to their general cognitive functioning. Odor detection was measured via vanillin solutions at the following concentrations: 150 mg/L, 30 mg/L, 15 mg/L, 3 mg/L, and .03 mg/L. The first condition of the test involved a scale administration of vanillin solutions. The second condition examined the change in air odour and it required vanillin solution of 30 mg/L and a metric ruler of 30 cm. The examiner had to place the solution at a specific distance point from each nostril. Odour identification sensitivity was secondarily measured. The results showed statistically significant differences in odour detection threshold between the two groups. In the unirhinal testing, left nostril differences of the two groups were definite. Hence, the B-ODT seems a promising instrument for very early cognitive impairment screening in older adult population.

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