scholarly journals Validating deep learning inference during chest X-ray classification for COVID-19 screening

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Robbie Sadre ◽  
Baskaran Sundaram ◽  
Sharmila Majumdar ◽  
Daniela Ushizima

AbstractThe new coronavirus unleashed a worldwide pandemic in early 2020, and a fatality rate several times that of the flu. As the number of infections soared, and capabilities for testing lagged behind, chest X-ray (CXR) imaging became more relevant in the early diagnosis and treatment planning for patients with suspected or confirmed COVID-19 infection. In a few weeks, proposed new methods for lung screening using deep learning rapidly appeared, while quality assurance discussions lagged behind. This paper proposes a set of protocols to validate deep learning algorithms, including our ROI Hide-and-Seek protocol, which emphasizes or hides key regions of interest from CXR data. Our protocol allows assessing the classification performance for anomaly detection and its correlation to radiological signatures, an important issue overlooked in several deep learning approaches proposed so far. By running a set of systematic tests over CXR representations using public image datasets, we demonstrate the weaknesses of current techniques and offer perspectives on the advantages and limitations of automated radiography analysis when using heterogeneous data sources.

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Okeke Stephen ◽  
Mangal Sain ◽  
Uchenna Joseph Maduh ◽  
Do-Un Jeong

This study proposes a convolutional neural network model trained from scratch to classify and detect the presence of pneumonia from a collection of chest X-ray image samples. Unlike other methods that rely solely on transfer learning approaches or traditional handcrafted techniques to achieve a remarkable classification performance, we constructed a convolutional neural network model from scratch to extract features from a given chest X-ray image and classify it to determine if a person is infected with pneumonia. This model could help mitigate the reliability and interpretability challenges often faced when dealing with medical imagery. Unlike other deep learning classification tasks with sufficient image repository, it is difficult to obtain a large amount of pneumonia dataset for this classification task; therefore, we deployed several data augmentation algorithms to improve the validation and classification accuracy of the CNN model and achieved remarkable validation accuracy.


IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 20235-20254
Author(s):  
Hanan S. Alghamdi ◽  
Ghada Amoudi ◽  
Salma Elhag ◽  
Kawther Saeedi ◽  
Jomanah Nasser

Author(s):  
Tanishka Dodiya

Abstract: COVID-19 also famously known as Coronavirus is one of the deadliest viruses found in the world, which has a high rate in both demise and spread. This has caused a severe pandemic in the world. The virus was first reported in Wuhan, China, registering causes like pneumonia. The first case was encountered on December 31, 2019. As of 20th October 2021, more than 242 million cases have been reported in more than 188 countries, and it has around 5 million deaths. COVID- 19 infected persons have pneumonia-like symptoms, and the infection damages the body's respiratory organs, making breathing difficult. The elemental clinical equipment as of now being employed for the analysis of COVID-19 is RT-PCR, which is costly, touchy, and requires specific clinical workforce. According to recent studies, chest X-ray scans include important information about the start of the infection, and this information may be examined so that diagnosis and treatment can begin sooner. This is where artificial intelligence meets the diagnostic capabilities of intimate clinicians. X-ray imaging is an effectively available apparatus that can be an astounding option in the COVID-19 diagnosis. The architecture usually used are VGG16, ResNet50, DenseNet121, Xception, ResNet18, etc. This deep learning based COVID detection system can be installed in hospitals for early diagnosis, or it can be used as a second opinion. Keywords: COVID-19, Deep Learning, CNN, CT-Image, Transfer Learning, VGG, ResNet, DenseNet


2021 ◽  
Vol 11 (17) ◽  
pp. 8227 ◽  
Author(s):  
Andrea Loddo ◽  
Fabio Pili ◽  
Cecilia Di Ruberto

COVID-19, an infectious coronavirus disease, caused a pandemic with countless deaths. From the outset, clinical institutes have explored computed tomography as an effective and complementary screening tool alongside the reverse transcriptase-polymerase chain reaction. Deep learning techniques have shown promising results in similar medical tasks and, hence, may provide solutions to COVID-19 based on medical images of patients. We aim to contribute to the research in this field by: (i) Comparing different architectures on a public and extended reference dataset to find the most suitable; (ii) Proposing a patient-oriented investigation of the best performing networks; and (iii) Evaluating their robustness in a real-world scenario, represented by cross-dataset experiments. We exploited ten well-known convolutional neural networks on two public datasets. The results show that, on the reference dataset, the most suitable architecture is VGG19, which (i) Achieved 98.87% accuracy in the network comparison; (ii) Obtained 95.91% accuracy on the patient status classification, even though it misclassifies some patients that other networks classify correctly; and (iii) The cross-dataset experiments exhibit the limitations of deep learning approaches in a real-world scenario with 70.15% accuracy, which need further investigation to improve the robustness. Thus, VGG19 architecture showed promising performance in the classification of COVID-19 cases. Nonetheless, this architecture enables extensive improvements based on its modification, or even with preprocessing step in addition to it. Finally, the cross-dataset experiments exposed the critical weakness of classifying images from heterogeneous data sources, compatible with a real-world scenario.


2021 ◽  
Vol 11 (10) ◽  
pp. 993
Author(s):  
Roberta Fusco ◽  
Roberta Grassi ◽  
Vincenza Granata ◽  
Sergio Venanzio Setola ◽  
Francesca Grassi ◽  
...  

Objective: To report an overview and update on Artificial Intelligence (AI) and COVID-19 using chest Computed Tomography (CT) scan and chest X-ray images (CXR). Machine Learning and Deep Learning Approaches for Diagnosis and Treatment were identified. Methods: Several electronic datasets were analyzed. The search covered the years from January 2019 to June 2021. The inclusion criteria were studied evaluating the use of AI methods in COVID-19 disease reporting performance results in terms of accuracy or precision or area under Receiver Operating Characteristic (ROC) curve (AUC). Results: Twenty-two studies met the inclusion criteria: 13 papers were based on AI in CXR and 10 based on AI in CT. The summarized mean value of the accuracy and precision of CXR in COVID-19 disease were 93.7% ± 10.0% of standard deviation (range 68.4–99.9%) and 95.7% ± 7.1% of standard deviation (range 83.0–100.0%), respectively. The summarized mean value of the accuracy and specificity of CT in COVID-19 disease were 89.1% ± 7.3% of standard deviation (range 78.0–99.9%) and 94.5 ± 6.4% of standard deviation (range 86.0–100.0%), respectively. No statistically significant difference in summarized accuracy mean value between CXR and CT was observed using the Chi square test (p value > 0.05). Conclusions: Summarized accuracy of the selected papers is high but there was an important variability; however, less in CT studies compared to CXR studies. Nonetheless, AI approaches could be used in the identification of disease clusters, monitoring of cases, prediction of the future outbreaks, mortality risk, COVID-19 diagnosis, and disease management.


2020 ◽  
Vol 77 (9) ◽  
pp. 597-602
Author(s):  
Xiaohua Wang ◽  
Juezhao Yu ◽  
Qiao Zhu ◽  
Shuqiang Li ◽  
Zanmei Zhao ◽  
...  

ObjectivesTo investigate the potential of deep learning in assessing pneumoconiosis depicted on digital chest radiographs and to compare its performance with certified radiologists.MethodsWe retrospectively collected a dataset consisting of 1881 chest X-ray images in the form of digital radiography. These images were acquired in a screening setting on subjects who had a history of working in an environment that exposed them to harmful dust. Among these subjects, 923 were diagnosed with pneumoconiosis, and 958 were normal. To identify the subjects with pneumoconiosis, we applied a classical deep convolutional neural network (CNN) called Inception-V3 to these image sets and validated the classification performance of the trained models using the area under the receiver operating characteristic curve (AUC). In addition, we asked two certified radiologists to independently interpret the images in the testing dataset and compared their performance with the computerised scheme.ResultsThe Inception-V3 CNN architecture, which was trained on the combination of the three image sets, achieved an AUC of 0.878 (95% CI 0.811 to 0.946). The performance of the two radiologists in terms of AUC was 0.668 (95% CI 0.555 to 0.782) and 0.772 (95% CI 0.677 to 0.866), respectively. The agreement between the two readers was moderate (kappa: 0.423, p<0.001).ConclusionOur experimental results demonstrated that the deep leaning solution could achieve a relatively better performance in classification as compared with other models and the certified radiologists, suggesting the feasibility of deep learning techniques in screening pneumoconiosis.


Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1480
Author(s):  
Nur-A-Alam Alam ◽  
Mominul Ahsan ◽  
Md. Abdul Based ◽  
Julfikar Haider ◽  
Marcin Kowalski

Currently, COVID-19 is considered to be the most dangerous and deadly disease for the human body caused by the novel coronavirus. In December 2019, the coronavirus spread rapidly around the world, thought to be originated from Wuhan in China and is responsible for a large number of deaths. Earlier detection of the COVID-19 through accurate diagnosis, particularly for the cases with no obvious symptoms, may decrease the patient’s death rate. Chest X-ray images are primarily used for the diagnosis of this disease. This research has proposed a machine vision approach to detect COVID-19 from the chest X-ray images. The features extracted by the histogram-oriented gradient (HOG) and convolutional neural network (CNN) from X-ray images were fused to develop the classification model through training by CNN (VGGNet). Modified anisotropic diffusion filtering (MADF) technique was employed for better edge preservation and reduced noise from the images. A watershed segmentation algorithm was used in order to mark the significant fracture region in the input X-ray images. The testing stage considered generalized data for performance evaluation of the model. Cross-validation analysis revealed that a 5-fold strategy could successfully impair the overfitting problem. This proposed feature fusion using the deep learning technique assured a satisfactory performance in terms of identifying COVID-19 compared to the immediate, relevant works with a testing accuracy of 99.49%, specificity of 95.7% and sensitivity of 93.65%. When compared to other classification techniques, such as ANN, KNN, and SVM, the CNN technique used in this study showed better classification performance. K-fold cross-validation demonstrated that the proposed feature fusion technique (98.36%) provided higher accuracy than the individual feature extraction methods, such as HOG (87.34%) or CNN (93.64%).


2020 ◽  
Author(s):  
Hanan Alghamdi ◽  
Ghada Amoudi ◽  
Salma Elhag ◽  
Kawther Saeedi ◽  
Jomanah Nasser

UNSTRUCTURED Chest X-ray (CXR) imaging is a standard and crucial examination method used for suspected cases of coronavirus disease (COVID-19). In profoundly affected or limited resource areas, CXR imaging is preferable owing to its availability, low cost, and rapid results. However, given the rapidly spreading nature of COVID-19, such tests could limit the efficiency of pandemic control and prevention. In response to this issue, artificial intelligence methods such as deep learning are promising options for automatic diagnosis because they have achieved state-of-the-art performance in the analysis of visual information and a wide range of medical images. This paper reviews and critically assesses the preprint and published reports between March and May 2020 for the diagnosis of COVID-19 via CXR images using convolutional neural networks and other deep learning architectures. Despite the encouraging results, there is an urgent need for public, comprehensive, and diverse datasets. Further investigations in terms of explainable and justifiable decisions are also required for more robust, transparent, and accurate predictions


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Ivo M. Baltruschat ◽  
Hannes Nickisch ◽  
Michael Grass ◽  
Tobias Knopp ◽  
Axel Saalbach

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