Book reviews: Computational Biochemistry and Biophysics, O. M. Becker, A. D. MacKerell, Jr., B. Roux and M. Watanabe (reviewed by Charles Laughton); Enzymes in Nonaqueous Solvents, Methods and Protocols, ed. Evgeny N. Vulfson, Peter J. Halling and Herbert L. Holland (reviewed by Karine Auclair); Bioactive Compounds from Natural sources, ed. Corrada Tringali (reviewed by W. Ayer); Natural Compounds in Cancer Chemotherapy, John Boik (reviewed by John Mann); Medicinal Chemistry – Into the Millenium, M. M. Campbell and I. S. Blagbrough (reviewed by Anita R. Maguire)

2001 ◽  
Vol 18 (5) ◽  
pp. 579-582
Keyword(s):  
Bioactive Compounds ◽  
Cancer Chemotherapy ◽  
Medicinal Chemistry ◽  
Natural Compounds ◽  
Nonaqueous Solvents ◽  
Natural Sources ◽  
Charles Laughton

scholarly journals An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities

2020 ◽  
Vol 21 (13) ◽  
pp. 4618 ◽  
Author(s):  
Francesca Annunziata ◽  
Cecilia Pinna ◽  
Sabrina Dallavalle ◽  
Lucia Tamborini ◽  
Andrea Pinto
Keyword(s):  
Scientific Community ◽  
Medicinal Chemistry ◽  
Biological Activities ◽  
Natural Compounds ◽  
Natural Sources ◽  
Wide Range ◽  
Living Organisms ◽  
Privileged Structures ◽  
Synthetic Approaches ◽  
Critical Overview

Privileged structures have been widely used as an effective template for the research and discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and it can be found in a considerable number of plants as well as in some fungi and bacteria. In the last years, these natural compounds have been gaining an increasing attention from the scientific community for their wide range of biological activities, mainly due to their ability to interact with diverse enzymes and receptors in living organisms. In addition, coumarin nucleus has proved to be easily synthetized and decorated, giving the possibility of designing new coumarin-based compounds and investigating their potential in the treatment of various diseases. The versatility of coumarin scaffold finds applications not only in medicinal chemistry but also in the agrochemical field as well as in the cosmetic and fragrances industry. This review is intended to be a critical overview on coumarins, comprehensive of natural sources, metabolites, biological evaluations and synthetic approaches.

Nutraceuticals from Marine Bionetworks

2019 ◽  
Vol 15 (4) ◽  
pp. 338-344
Author(s):  
Abhitav Tiwari ◽  
Shambhawi Pritam ◽  
Keerti Mishra ◽  
Mehshara Khan ◽  
Neeraj Upmanyu ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Bioactive Compounds ◽  
Daily Basis ◽  
Marine Organisms ◽  
Bioactive Molecules ◽  
Natural Sources ◽  
Nutraceutical Compounds ◽  
Potential Sources ◽  
Immense Potential ◽  
Potential Use

“Nutrition” and “Pharmaceutical” together build up the perception of “Nutraceuticals” that refer to the food or dietary supplements that help to incorporate additional health benefits to the fundamental sustenance accomplished on daily basis. Each nutraceutical contains one or more bioactive molecules that are usually obtained by chemical and/ or biotechnological synthesis or by extraction from natural sources. Among the natural sources, marine bionetwork possess immense potential for the presence of bioactive compounds. Some of these bioactive compounds as isolated from marine sources, have potential use as nutraceuticals. This mini review provides a brief overview of nutraceutical compounds from marine sources that are currently under research and/or have been commercialized. A detailed discussion on the biochemical categories of compounds and the marine organisms that play as potential sources of these bioactive nutraceutical compounds have been included.

scholarly journals Medicinal Plants and Its Pharmacological Values

2021 ◽  
Author(s):  
Smita G. Bhat
Keyword(s):  
Medicinal Plants ◽  
Natural Resources ◽  
Bioactive Compounds ◽  
Biological Diversity ◽  
Biological Activities ◽  
Chemical Compounds ◽  
Natural Sources ◽  
Plant Parts ◽  
New Drug ◽  
Important Chemical

Plants have been used as a source of medicine for the treatment of different diseases from thousands of years ago. There is numerous evidences are available for use of plants as a medicine in the treatment of diseases in Indian, Egyptian, Chinese, Greek and Roman system of medicine. Pharmacognosy is the study of medicines derived from natural sources, mainly from plants which may further lead to development of new drug. The exploration, extraction and screening of biological diversity such as herbs, spices, microbes and other natural resources is the worldwide activity in recent years. Phytochemicals are the naturally available bioactive compounds which are derived from different plant parts and are primarily responsible for biological activities. The most important chemical compounds which are present in the plants are alkaloids, phenols, saponins, carbohydrates, terpenoids, steroids, flavonoids and tannins etc.

Cancer Chemotherapy, Bioactive Compounds, and Immunotherapy

2021 ◽  
pp. 45-87
Author(s):  
Eva Fischer-Fodor ◽  
Anna Andreea Zimta ◽  
Mihail Buse ◽  
Ioana Berindan Neagoe
Keyword(s):  
Bioactive Compounds ◽  
Cancer Chemotherapy

scholarly journals Origins and Bioactivities of Natural Compounds Derived from Marine Ascidians and Their Symbionts

Marine Drugs ◽  
2019 ◽  
Vol 17 (12) ◽  
pp. 670 ◽  
Author(s):  
Xiaoju Dou ◽  
Bo Dong
Keyword(s):  
Natural Products ◽  
Secondary Metabolites ◽  
Bioactive Compounds ◽  
Natural Compounds ◽  
Marine Animals ◽  
Lead Compounds ◽  
Chemical Structures ◽  
Complex Interactions ◽  
Novel Structures ◽  
Important Drug

Marine ascidians are becoming important drug sources that provide abundant secondary metabolites with novel structures and high bioactivities. As one of the most chemically prolific marine animals, more than 1200 inspirational natural products, such as alkaloids, peptides, and polyketides, with intricate and novel chemical structures have been identified from ascidians. Some of them have been successfully developed as lead compounds or highly efficient drugs. Although numerous compounds that exist in ascidians have been structurally and functionally identified, their origins are not clear. Interestingly, growing evidence has shown that these natural products not only come from ascidians, but they also originate from symbiotic microbes. This review classifies the identified natural products from ascidians and the associated symbionts. Then, we discuss the diversity of ascidian symbiotic microbe communities, which synthesize diverse natural products that are beneficial for the hosts. Identification of the complex interactions between the symbiont and the host is a useful approach to discovering ways that direct the biosynthesis of novel bioactive compounds with pharmaceutical potentials.

scholarly journals Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species

Marine Drugs ◽  
2018 ◽  
Vol 16 (11) ◽  
pp. 408 ◽  
Author(s):  
Rosario Nicoletti ◽  
Francesco Vinale
Keyword(s):  
Microbial Diversity ◽  
Bioactive Compounds ◽  
Scientific Community ◽  
Human Life ◽  
Trichoderma Species ◽  
Natural Sources ◽  
The Impact

The impact of bioactive compounds from natural sources on human life, particularly in pharmacology and biotechnology, has challenged the scientific community to explore new environmental contexts and the associated microbial diversity. [...]

scholarly journals Syntheses of Marchantins C, O and P as Promising Highly Bioactive Compounds

2011 ◽  
Vol 6 (3) ◽  
pp. 1934578X1100600
Author(s):  
Andreas Speicher ◽  
Judith Holz ◽  
Alexandra Hoffmann
Keyword(s):  
Total Synthesis ◽  
Bioactive Compounds ◽  
Natural Compounds ◽  
Marchantia Polymorpha ◽  
Antitumor Activities ◽  
Microtubule Inhibitor ◽  
First Time

Recently, remarkable microtubule inhibitor and antitumor activities of the bis(bibenzyl) marchantin C – isolated from liverworts like Marchantia polymorpha since 1983 – were found. In this paper we describe the efficient total synthesis of this subtype of bis(bibenzylic) compounds with two biarylether connections. Two selectively methylated derivatives known as natural compounds marchantin O and P were synthesized for the first time by modification of the arene subunits and can now be considered as promising highly bioactive compounds.

Sign in / Sign up

Export Citation Format

Share Document