High selectivity towards small copper ions by a preorganized phenanthroline-derived tetradentate ligand and new insight into the complexation mechanism

2014 ◽  
Vol 43 (33) ◽  
pp. 12470-12473 ◽  
Author(s):  
Cheng-Liang Xiao ◽  
Qun-Yan Wu ◽  
Lei Mei ◽  
Li-Yong Yuan ◽  
Cong-Zhi Wang ◽  
...  
Keyword(s):  
High Selectivity ◽  
Copper Ions ◽  
Tetradentate Ligand ◽  
Complexation Mechanism ◽  
Insight Into

A preorganized tetradentate phenanthroline-derived amide ligand was found to show high selectivity towards small copper ions.

Highly Selective Separation and Enrichment of Phosphopeptides by Uranyl-Salophen Immobilized Silica Gel Material

2015 ◽  
Vol 1095 ◽  
pp. 341-344 ◽  
Author(s):  
Can Hui Xu ◽  
Guang Liang Zhang ◽  
Xin Zhou ◽  
Xi Lin Xiao ◽  
Chang Ming Nie ◽  
...  
Keyword(s):  
Silica Gel ◽  
Metal Ion ◽  
High Selectivity ◽  
Separation Efficiency ◽  
Solid Phase ◽  
Tetradentate Ligand ◽  
Peptide Mixtures ◽  
New Material ◽  
Solid Phase Material

The characterization of phosphoproteins requires highly specific methods for the separation and enrichment of phosphopeptides. Here we report a novel metal ion-immobilized solid phase material for the separation and enrichment of phosphopeptides. The material is uranyl-salophen-silica gel (USSG) particles in which salophen is a tetradentate ligand of uranyl ion. In USSG salophen is connected on the surface of silica gel and uranyl is bound on the surface through its coordination with salophen. Phosphopeptides can be selectively retained by USSG because uranyl-salophen can bind phosphate moiety with strong affinity and high selectivity. The new material USSG has been successfully used for the separation of phosphopeptides from peptide mixtures with the separation efficiency of 97.0% to 97.4%.

scholarly journals Feasibility of nanoscale zero-valent iron loaded sediment-based biochar (nZVI-SBC) for simultaneous removal of nitrate and phosphate: high selectivity towards dinitrogen and synergistic mechanism

2021 ◽  
Author(s):  
Xiaohui Liu ◽  
Jia Wei ◽  
Liangang Hou ◽  
Yuhan Zhu ◽  
Yaodong Wu ◽  
...  
Keyword(s):  
High Selectivity ◽  
Phosphate Removal ◽  
Zero Valent Iron ◽  
Polluted Water ◽  
Nitrogen And Phosphorus ◽  
Nanoscale Zero Valent Iron ◽  
Synergistic Mechanism ◽  
Loading Ratio ◽  
Anoxic Environment ◽  
Complexation Mechanism

Abstract In the process of water treatment, excessive nitrogen and phosphorus pollutants are of great concern. Therefore, we prepared nanoscale zero-valent iron loaded on sediment-based biochar (nZVI-SBC) to conduct nitrate and phosphate removal at the same time. The characterization demonstrated that nZVI-SBC was successfully synthesized, which had obvious advantages for larger specific surface area and better dispersion compared with pure nZVI. The batch experiments indicated that the best loading ratio of nZVI to SBC and optimum dosage for nitrate and phosphate were 1:1and 2 g·L-1, respectively. Their removal by nZVI-SBC was an acid-driven process. Anoxic environment was more conducive to the reduction of nitrate while the phosphate removal was fond of oxygen environment. 77.78% of nitrate and 99.21% of phosphate have been successfully removed, mainly depending on reduction and complexation mechanism, respectively. Moreover, nZVI-SBC had higher N2 selectivity and produced less ammonium than nZVI. The interaction between nitrate and phosphate was studied to manifest that they had different degrees of inhibition during the removal of the other. Our research indicated that nZVI-SBC has great potential for remediation of nitrogen and phosphorus polluted water.

High selectivity and reversibility/reusability red emitting fluorescent probe for copper ions detection and imaging in living cells

2019 ◽  
Vol 206 ◽  
pp. 125-131 ◽  
Author(s):  
Hanzhi Ni ◽  
Qingming Wang ◽  
Lei Jin ◽  
Wenling Wang ◽  
Lihui Dai ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Copper Ions ◽  
Living Cells

scholarly journals A Comprehensive Review on Thiophene Based Chemosensors

2021 ◽  
Author(s):  
Rikitha S. Fernandes ◽  
Nitinkumar S. Shetty ◽  
Priyanka Mahesha ◽  
Santhosh L. Gaonkar
Keyword(s):  
High Selectivity ◽  
Low Cost ◽  
Photophysical Properties ◽  
Biological Systems ◽  
Detection Mechanism ◽  
Comprehensive Review ◽  
Thiophene Derivatives ◽  
Analyte Detection ◽  
Insight Into

AbstractThe recognition and sensing of various analytes in aqueous and biological systems by using fluorometric or colorimetric chemosensors possessing high selectivity and sensitivity, low cost has gained enormous attention. Furthermore, thiophene derivatives possess exceptional photophysical properties compared to other heterocycles, and therefore they can be employed in chemosensors for analyte detection. In this review, we have tried to explore the design and detection mechanism of various thiophene-based probes, practical applicability, and their advanced models (design guides), which could be thoughtful for the synthesis of new thiophene-based probes. This review provides an insight into the reported chemosensors (2008-2020) for thiophene scaffold as effective emission and absorption-based chemosensors.

scholarly journals Flavin-Dependent Halogenases Catalyze Enantioselective Olefin Halocyclization

2020 ◽  
Author(s):  
Dibyendu Mondal ◽  
Brian F. Fisher ◽  
Yuhua Jiang ◽  
Jared C. Lewis
Keyword(s):  
Organic Chemistry ◽  
Catalytic Activity ◽  
High Selectivity ◽  
Organic Transformations ◽  
Docking Simulations ◽  
Bond Forming ◽  
Reaction Optimization ◽  
Wide Range ◽  
Site Selective ◽  
Insight Into

<div><div><div><p>Catalytic enantioselective halocyclization of alkenes is a powerful bond forming tool in synthetic organic chemistry and a key step in the biosynthesis of several natural products. To date, however, no examples of enantioselective halocyclization of simple achiral olefins catalyzed by enzymes have been reported. Herein, we report that flavin-dependent halogenases (FDHs) previously engineered to catalyze site-selective aromatic halogenation can also catalyze bromolactonization of olefins with high enantioselectivity and near-native catalytic proficiency. Analysis of the selectivity of FDH variants along the lineage for the most selective enzymes reveals mutations responsible for the emergence of halocyclase activity, and docking simulations provide insight into the origins of improvements imparted by these mutations. High selectivity was achieved by characterizing and mitigating the release of HOBr from FDH variants using a combination of protein engineering and reaction optimization. Given the range of different halocyclization reactions and other organic transformations that proceed via oxidative halogenation, this expansion of FDH catalytic activity bodes well for the development of a wide range of biocatalytic halogenation reactions.</p></div></div></div>

scholarly journals Detection of Cu2+ Ions with GGH Peptide Realized with Si-Nanoribbon ISFET

Sensors ◽  
2019 ◽  
Vol 19 (18) ◽  
pp. 4022 ◽  
Author(s):  
Olena Synhaivska ◽  
Yves Mermoud ◽  
Masoud Baghernejad ◽  
Israel Alshanski ◽  
Mattan Hurevich ◽  
...  
Keyword(s):  
Field Effect Transistor ◽  
Copper Ions ◽  
Specific Binding ◽  
Cost Effective ◽  
Detection Methods ◽  
Ligand Interaction ◽  
Amine Groups ◽  
Effect Transistor ◽  
Pre Treatment ◽  
Insight Into

The presence of heavy metal ions such as copper in the human body at certain concentrations and specific conditions can lead to the development of different diseases. The currently available analytical detection methods remain expensive, time-consuming, and often require sample pre-treatment. The development of specific and quantitative, easy-in-operation, and cost-effective devices, capable of monitoring the level of Cu2+ ions in environmental and physiological media, is necessary. We use silicon nanoribbon (SiNR) ion-sensitive field effect transistor (ISFET) devices modified with a Gly–Gly–His peptide for the detection of copper ions in a large concentration range. The specific binding of copper ions causes a conformational change of the ligand, and a deprotonation of secondary amine groups. By performing differential measurements, we gain a deeper insight into the details of the ion–ligand interaction. We highlight in particular the importance of considering non-specific interactions to explain the sensors’ response.

Conjugation-induced fluorescence labelling of mesoporous silica nanoparticles for the sensitive and selective detection of copper ions in aqueous solution

2014 ◽  
Vol 38 (12) ◽  
pp. 6017-6024 ◽  
Author(s):  
Jingjing Cui ◽  
Shangfeng Wang ◽  
Kai Huang ◽  
Yongsheng Li ◽  
Wenru Zhao ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Detection Limit ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
High Selectivity ◽  
Copper Ions ◽  
Mesoporous Silica Nanoparticles ◽  
Selective Detection ◽  
Fluorescence Labelling

A newly developed fluorescent “on–off” chemosensor presents high selectivity towards Cu2+ with detection limit as low as 0.28 μM.

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