Physicochemical characterization of diacyltetrol-based lipids consisting of both diacylglycerol and phospholipid headgroups

RSC Advances ◽  
2014 ◽  
Vol 4 (42) ◽  
pp. 21971-21978 ◽  
Author(s):  
Narsimha Mamidi ◽  
Sukhamoy Gorai ◽  
Bolledu Ravi ◽  
Debasis Manna
Keyword(s):  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Anionic Lipid ◽  
Phospholipid Headgroups ◽  
First Time

Synthesis and physicochemical properties of a family of diacyltetrol-based hybrid lipids, containing both diacylglycerol and anionic lipid headgroups within the same moiety, have been reported for the first time.

scholarly journals Physicochemical Characterization Cascade of Nanoadjuvant–Antigen Systems for Improving Vaccines

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 544
Author(s):  
Giuditta Guerrini ◽  
Antonio Vivi ◽  
Sabrina Gioria ◽  
Jessica Ponti ◽  
Davide Magrì ◽  
...  
Keyword(s):  
Immune Response ◽  
Protein Structure ◽  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Protein Antigen ◽  
Efficacy And Safety

Adjuvants have been used for decades to enhance the immune response to vaccines, in particular for the subunit-based adjuvants. Physicochemical properties of the adjuvant-protein antigen complexes, such as size, morphology, protein structure and binding, influence the overall efficacy and safety of the vaccine. Here we show how to perform an accurate physicochemical characterization of the nanoaluminum–ovalbumin complex. Using a combination of existing techniques, we developed a multi-staged characterization strategy based on measurements of increased complexity. This characterization cascade has the advantage of being very flexible and easily adaptable to any adjuvant-protein antigen combinations. It will contribute to control the quality of antigen–adjuvant complexes and immunological outcomes, ultimately leading to improved vaccines.

Mineralogical and physicochemical characterization of selected Portuguese Mesozoic-Cenozoic muddy/clayey raw materials to be potentially used as healing clays

Clay Minerals ◽  
2010 ◽  
Vol 45 (2) ◽  
pp. 229-240 ◽  
Author(s):  
M. Rebelo ◽  
F. Rocha ◽  
E. Ferreira Da Silva
Keyword(s):  
Physicochemical Properties ◽  
Mineral Water ◽  
Raw Materials ◽  
Physicochemical Characterization ◽  
Mineralogical Composition ◽  
Exchange Capacity ◽  
Water Mixture ◽  
X Ray Diffraction ◽  
Geological Formations

AbstractThe use of pelitic geological materials for the treatment of muscle-bone-skin pathologies, by application of a cataplasm made of clay and mineral water mixture, is currently receiving attention and interest from the general public and scientific community. In Portugal there are several natural occurrences of clays/muds which are used for pelotherapy and/or geotherapy. These are carried out either indoors (thalassotherapy and thermal centres) or outdoors, in natural sites generally located near the seaside. The aim of this study is to assess the mineralogical and physicochemical properties of Portuguese raw materials for therapeutic purposes. These materials were collected from different Portuguese Mesozoic-Cenozoic geological formations located in the neighbourhood of thermal centres or at beaches known from their empirical applications. X-ray diffraction (XRD) and scanning electron microscopy (SEM-EDS) were used to assess the mineralogical composition of these clays. Physicochemical properties, such as specific surface area, cation exchange capacity, plasticity/abrasiveness indices and heat diffusiveness were also determined. Having distinct geological ages and genesis, the materials examined are mainly illitic. Less abundant kaolinite and smectite are also present. With respect to their physicochemical properties, all samples have good thermal properties which make them potentially suitable for therapeutic or aesthetic purposes.

Physicochemical characterization of organogels prepared from menhaden oil or structured lipid with phytosterol blend or sucrose stearate/ascorbyl palmitate blend

2019 ◽  
Vol 10 (1) ◽  
pp. 180-190 ◽  
Author(s):  
Sarah A. Willett ◽  
Casimir C. Akoh
Keyword(s):  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Ascorbyl Palmitate ◽  
Structured Lipid ◽  
Menhaden Oil

Phytosterol blend and sucrose stearate/ascorbyl palmitate blend organogelators and different oil phases formed organogels with different physicochemical properties.

Physicochemical Characterization of Nano-Hydroxyapatite Prepared by a Wet Method

2017 ◽  
Vol 758 ◽  
pp. 189-193
Author(s):  
Jia Yun Xu ◽  
Shohei Kasugai ◽  
Hideki Aoki ◽  
Takayuki Terukina ◽  
Makoto Otsuka
Keyword(s):  
Body Temperature ◽  
Phosphoric Acid ◽  
Acid Solution ◽  
Physicochemical Properties ◽  
Calcium Hydroxide ◽  
Physicochemical Characterization ◽  
Phosphoric Acid Solution ◽  
Reaction Conditions ◽  
Lower Temperature

Recently nano-hydroxyapatite (nano-HA) has been used as a new biomaterial in medical and dental fields. There are many methods to synthesize the nano-HA. In the present study, the nano-HA was synthesized under various reaction conditions by a wet method using neutralization reaction of calcium hydroxide suspension and phosphoric acid solution. The physicochemical properties of the nano-HA were characterized by XRD, FTIR, TG and TEM. The XRD, FTIR and TEM results indicated that the nano-HA samples were pure and the sizes were less than 50 nm. However, all samples contained carbonate and the contents were determined to be 2-4% by TG. The crystallinity of the nano-HA increased higher at body temperature of 37°C than at lower temperature of 7-10°C.

scholarly journals STUDIES OF NERVE PROTEINS. ISOLATION AND PHYSICOCHEMICAL CHARACTERIZATION OF A PROTEIN FROM LOBSTER NERVE

1951 ◽  
Vol 34 (6) ◽  
pp. 853-863 ◽  
Author(s):  
Myles Maxfield
Keyword(s):  
Absorption Spectrum ◽  
Physicochemical Properties ◽  
Particle Shape ◽  
Physicochemical Characterization ◽  
Pure Form

1. A procedure is described by which several protein constituents may be obtained from extracts of lobster claw nerves. One of these fractions, designated fraction A, representing 10 per cent of the total non-dialyzable material of the extracts, has been obtained in relatively (85 per cent) pure form. 2. This component has been characterized with respect to its physicochemical properties, particle shape, dimensions, and absorption spectrum.

scholarly journals Kinetic and energetic insights in the dissipative non-equilibrium operation of an autonomous light-powered supramolecular pump

2021 ◽  
Author(s):  
Stefano Corrà ◽  
Marina Tranfik Bakic ◽  
Jessica Groppi ◽  
Massimo Baroncini ◽  
Serena Silvi ◽  
...  
Keyword(s):  
Self Assembly ◽  
Physicochemical Characterization ◽  
Theoretical Models ◽  
External Source ◽  
Light Energy ◽  
Artificial System ◽  
Depth Study ◽  
First Time ◽  
Non Equilibrium

Natural and artificial autonomous molecular machines operate by constantly dissipating energy coming from an external source to maintain a non-equilibrium state. The in-depth study of these dissipative states is highly challenging as they exist only as long as energy is provided. Here we report on the detailed physicochemical characterization of the dissipative operation of a supramolecular pump transducing light energy into chemical energy by shifting the equilibrium of self-assembly reactions. The composition of the system under light irradiation was followed in real-time by 1H NMR and parameters such as the dissipation and the energy storage at the steady state were extracted for four different irradiation intensities. For the first time in an artificial system, we quantitatively probed the relationship between the light energy input and the deviation of the dissipative state from thermodynamic equilibrium. Our results also provide a testing ground for newly developed theoretical models.

Isolation and evaluation of some physicochemical properties of Parkia biglobosa starch

2009 ◽  
Vol 81 (1) ◽  
pp. 97-104 ◽  
Author(s):  
Nnemeka Edith Ihegwuagu ◽  
Moses Olubayo Omojola ◽  
Martins Ochobiojo Emeje ◽  
Olobayo Olufunsho Kunle
Keyword(s):  
Physicochemical Properties ◽  
Food Industry ◽  
Corn Starch ◽  
Physicochemical Characterization ◽  
Parkia Biglobosa ◽  
Locust Bean ◽  
African Locust Bean

This paper describes the isolation and physicochemical characterization of starch obtained from Parkia biglobosa (African locust bean). The results show that the properties of starch from this source compare favorably with those of corn starch BP, and suggest that it could be useful as a stabilizer in baking powders and as an emulsifier in the food industry.

scholarly journals Extraction and Physicochemical Characterization of Oil from Unripe Plantain (Musa Paradisiaca) Peels

2020 ◽  
pp. 151-155
Author(s):  
Orodu Victor Enearepuadoh ◽  
Igara Evawere Abigail
Keyword(s):  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Iodine Content ◽  
Acid Value ◽  
Physicochemical Analysis ◽  
Human Consumption ◽  
Musa Paradisiaca ◽  
The Mean ◽  
The Stability

Extraction and physicochemical analysis of oil from unripe plantain (Musa paradisiaca) peels was carried out using cold extraction method. The peels were washed with distilled water, sun dried for 3 hours and oven dried for 6 hours at 85oC. It was then ground thoroughly. 700g of the sample was weighed and 1.20 liter of n-hexane was added for 72 hours. It was placed in a water bath for the evaporation of the solvent. The physicochemical properties determined were Saponification Value (SV), Iodine Value (IV), Free Fatty Acid Value (FFA), Peroxide Value (PV), Acid Value (AV) the mean results obtained SV 335.18mg/KOH/g, IV 7.16gI2/100g, FFA 338.76mg/KOH/g, AV 696.35mg/KOH/g and PV 328.46meq/kg. In comparing these physicochemical properties with the standard given by WHO/FAO, it was observed that IV and PV were below the range, SV, AV and FFA was above the range. Hence, the oil obtained from unripe plantain (Musa paradisiaca) peels is not fit for human consumption because AV, SV and FFA are higher than the standard given by WHO/FAO rather it can be used for making of soap and shampoos, PV showed the stability of the oil and IV indicates it’s nondrying quality which will not be suitable for ink and paint making due to its low iodine content.

scholarly journals Physicochemical Characterization of Febuxostat Microcomplexes with Parent and Modified Cyclodextrins

2018 ◽  
Vol 17 (1) ◽  
pp. 51-63
Author(s):  
Sayee V Aher ◽  
Yogesh V Pore
Keyword(s):  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Log P ◽  
Phase Solubility ◽  
Solubility Curve ◽  
Drying Process ◽  
Linear Type ◽  
Modified Cyclodextrins ◽  
Dissolution Properties

Febuxostat, a BCS class II antigout drug was complexed with β-cyclodextrin (βCD), hydroxypropyl-β- cyclodextrin (HPβCD) and / or methyl-β-cyclodextrin (MβCD), to improve its physicochemical properties. Earlier phase solubility and thermodynamic investigations in acetate buffer (pH 4.5) illustrated AL (linear) type of solubility curve and enthalpy driven complexation process, respectively. The association constant and complexation efficiency of modified cyclodextrins (CDs) were significantly higher than that of parent cyclodextrin (CD). The microcomplexes prepared by spray drying process were examined for their spectral, diffractometric, thermal, particle size, saturation solubility, Log P and dissolution properties. The physicochemical properties of pure drug were improved upon complexation with CDs. However, modified CDs produced amorphous micro-complexes contributing for their better performance as compared to parent CD.Dhaka Univ. J. Pharm. Sci. 17(1): 51-63, 2018 (June)

Sign in / Sign up

Export Citation Format

Share Document