Molecular design of the amphiphilic AB diblock copolymer toward one-step synthesis of amino-group functionalized large pore mesoporous silica

RSC Advances ◽  
2014 ◽  
Vol 4 (81) ◽  
pp. 43047-43051 ◽  
Author(s):  
Dongpo Xu ◽  
Yuan Yao ◽  
Lu Han ◽  
Shunai Che
Keyword(s):  
Acrylic Acid ◽  
Mesoporous Silica ◽  
Pore Size ◽  
Diblock Copolymer ◽  
Molecular Design ◽  
Amino Group ◽  
Structure Directing Agent ◽  
Functionalized Mesoporous Silica ◽  
One Step ◽  
Loading Amount

A functionalized mesoporous silica with an amino group loading amount of 3.1 mmol g−1 and a pore size of 27.5 nm was achieved by the co-structure directing agent (CSDA) method using poly(styrene)-b-poly(acrylic acid) (PS-b-PAA) as the template.

Efficient Removal of Cd2+ by the Mesoporous Silica Functionalized by APTES

2013 ◽  
Vol 726-731 ◽  
pp. 2409-2412
Author(s):  
Xiao Feng Cai ◽  
Kang Wei Ji ◽  
Wan Hao Wu ◽  
Jie Hou ◽  
Shi You Hao
Keyword(s):  
Aqueous Solution ◽  
Mesoporous Silica ◽  
Ph Value ◽  
High Surface ◽  
High Surface Area ◽  
Efficient Removal ◽  
Structure Directing Agent ◽  
Functionalized Mesoporous Silica ◽  
Adsorption Desorption ◽  
Large Pore Size

Amino-functionalized mesoporous silica (AFMS) with high amino loading, high surface area, and large pore size was synthesized using the anionic surfactant N-lauroylsarcosine sodium (Sar-Na) as template and 3-aminopropyltriethoxysilane (APTES) as co-structure directing agent (CSDA). The synthesized AFMS was characterized by N2adsorption-desorption, TEM and elemental analyzer. The results of the removal of Cd2+from aqueous solution showed that the pH value of aqueous solution affected the removal efficiency of Cd2+greatly, and that unary adsorption isotherm of Cd2+on the AFMS was well described by the Sips isotherm model, in which the adsorption capacity was 2.43 mmol/g for Cd2+, much higher than the literature data.

scholarly journals One-step synthesis of zinc-encapsulated MCM-41 as H2S adsorbent and optimization of adsorption parameters

2020 ◽  
Vol 3 (02) ◽  
pp. 74-81
Author(s):  
Nastaran Hazrati ◽  
Ali Akbar Miran Beigi ◽  
Majid Abdouss ◽  
Amir Vahid
Keyword(s):  
Pore Diameter ◽  
High Specific Surface Area ◽  
Adsorption Parameters ◽  
N2 Adsorption ◽  
Structure Directing Agent ◽  
Functionalized Mesoporous Silica ◽  
One Step ◽  
Ammonia Aqueous Solution ◽  
Adsorption Desorption ◽  
Mcm 41

The nano-sized structure of well-ordered Zn@MCM-41 adsorbent was synthesized through a direct hydrothermal method using CTAB as a structure-directing agent in an ammonia aqueous solution with different amounts of zinc acetylacetonate which were inserted into the structure-directing agent's loop during the synthesis. The XRD, HRTEM, and N2 adsorption-desorption isotherms were used to characterize the prepared ZnO functionalized mesoporous silica samples. As a result, the presence of ZnO in highly-ordered MCM-41's pore was proved as well as maintenance of the ordered mesostructure of MCM-41. The materials were possessed with a high specific surface area (1114-509 m2.g-1) and a large pore diameter (4.03-3.27 nm). Based on the obtained results from the adsorption of H2S gas in a lab-made setup, the Znx@MCM-41 showed the superior ability to increase of ZnO amount up to 7 hours as a breakthrough point. 

scholarly journals Mesoporous Silica with Covalently Immobilized Anthracene as Adsorbent for SPE Recovery of PAHs Pollutants from Highly Lipidic Solutions

2020 ◽  
Author(s):  
Albina Mikhraliieva ◽  
Rodrigo Araújo Gonçalves ◽  
Volodymyr Zaitsev
Keyword(s):  
Mesoporous Silica ◽  
Vegetable Oil ◽  
Myristic Acid ◽  
Polar Solvent ◽  
Dynamic Adsorption ◽  
Functionalized Mesoporous Silica ◽  
High Lipid ◽  
Two Samples ◽  
One Step ◽  
Π Stacking Interaction

Two samples of functionalized mesoporous silica containing anchored anthrylmethylamine groups (SiO<sub>2</sub>-Ant) have been prepared by surface assembling (1) and one step silane immobilization (2). Both adsorbents can be attributed to bimodal balanced hydrophobic-hydrophilic adsorbents with loading of anthracene groups about 15-33%. The adsorbents have been used for SPE of anthracene from organic solvents (acetonitrile, acetone and heptane) and model solutions of lipids (myristic acid and vegetable oil). The obtained results were compared with commercial C18 SPE cartridge. While C18 cartridge recovers anthracene from water-containing media (acetonitrile/water, 1/1), SiO<sub>2</sub>-Ant cartridges much more efficient in extraction of anthracene from non-polar solvent (heptane). Lipids macrocomponents such as myristic acid and vegetable oil do not decrease the dynamic adsorption capacity and recovery of the model PAH on SiO<sub>2</sub>-Ant. It was demonstrated that π-π stacking interaction with the analyte determine the selectivity of SiO<sub>2</sub>-Ant towards of anthracene. This makes SiO<sub>2</sub>-Ant attractive for selective pre-concentration of PAHs from high lipid content objects, such as vegetable oils.

scholarly journals Mesoporous Silica with Covalently Immobilized Anthracene as Adsorbent for SPE Recovery of PAHs Pollutants from Highly Lipidic Solutions

2020 ◽  
Author(s):  
Albina Mikhraliieva ◽  
Rodrigo Araújo Gonçalves ◽  
Volodymyr Zaitsev
Keyword(s):  
Mesoporous Silica ◽  
Vegetable Oil ◽  
Myristic Acid ◽  
Polar Solvent ◽  
Dynamic Adsorption ◽  
Functionalized Mesoporous Silica ◽  
High Lipid ◽  
Two Samples ◽  
One Step ◽  
Π Stacking Interaction

Two samples of functionalized mesoporous silica containing anchored anthrylmethylamine groups (SiO<sub>2</sub>-Ant) have been prepared by surface assembling (1) and one step silane immobilization (2). Both adsorbents can be attributed to bimodal balanced hydrophobic-hydrophilic adsorbents with loading of anthracene groups about 15-33%. The adsorbents have been used for SPE of anthracene from organic solvents (acetonitrile, acetone and heptane) and model solutions of lipids (myristic acid and vegetable oil). The obtained results were compared with commercial C18 SPE cartridge. While C18 cartridge recovers anthracene from water-containing media (acetonitrile/water, 1/1), SiO<sub>2</sub>-Ant cartridges much more efficient in extraction of anthracene from non-polar solvent (heptane). Lipids macrocomponents such as myristic acid and vegetable oil do not decrease the dynamic adsorption capacity and recovery of the model PAH on SiO<sub>2</sub>-Ant. It was demonstrated that π-π stacking interaction with the analyte determine the selectivity of SiO<sub>2</sub>-Ant towards of anthracene. This makes SiO<sub>2</sub>-Ant attractive for selective pre-concentration of PAHs from high lipid content objects, such as vegetable oils.

scholarly journals Hybrid mesoporous silica with controlled drug release

2019 ◽  
Vol 84 (9) ◽  
pp. 1027-1039 ◽  
Author(s):  
László Almásy ◽  
Ana-Maria Putz ◽  
Qiang Tian ◽  
Gennady Kopitsa ◽  
Tamara Khamova ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Drug Loading ◽  
Sol Gel ◽  
Nitrogen Adsorption ◽  
Controlled Drug Release ◽  
Ammonium Bromide ◽  
Structure Directing Agent ◽  
One Step

The mesoporous silica particles were prepared by the sol?gel method in one-step synthesis, in acidic conditions, from tetraethoxysilane (TEOS) and methyltriethoxysilane (MTES), varying the mole ratio of the silica precursors. Nitric acid was used as catalyst at room temperature and hexadecyltrimethyl ammonium bromide (CTAB) as structure directing agent. Optical properties, porosity and microstructure of the materials in function of the MTES/TEOS ratio were evaluated using infrared spectroscopy, nitrogen adsorption and small angle X-ray scattering. All materials showed the ordered pore structure and the high specific surfaces, making them suitable as the drug delivery systems. Drug loading and release tests using ketoprofen were performed to assess their performance for drug delivery applications. The amount of the methylated precursor used in the synthesis had little effect on the drug loading capacity, but had a strong influence on the initial rate of the drug release.

scholarly journals Mesoporous Silica With Covalently Immobilized Anthracene As Adsorbent For SPE Recovery Of PAHs Pollutants From Highly Lipidic Solutions

2021 ◽  
Vol 16 (1) ◽  
pp. 5-14
Author(s):  
Albina Mikhraliieva ◽  
Rodrigo A. Gonзalves ◽  
Vladimir Zaitsev
Keyword(s):  
Mesoporous Silica ◽  
Vegetable Oil ◽  
Myristic Acid ◽  
Solid Phase ◽  
Functionalized Mesoporous Silica ◽  
High Lipid ◽  
Two Samples ◽  
Polycyclic Aromatic ◽  
One Step ◽  
Π Stacking Interaction

Two samples of functionalized mesoporous silica containing anchored anthrylmethylamine groups (SiO2-Ant) have been prepared by surface assembling (1) and one step silane immobilization (2). Both adsorbents can be attributed to bimodal balanced hydrophobic-hydrophilic adsorbents with loading of anthracene groups about 15-33 %. The adsorbents have been used for solid-phase extraction (SPE) of anthracene from organic solvents (acetonitrile, acetone and heptane) and model solutions of lipids (myristic acid and vegetable oil). The obtained results were compared with commercial C18 SPE cartridge. While C18 cartridge recovers anthracene from water-containing media (acetonitrile/water, 1/1), SiO2-Ant cartridges much more efficient in extraction of anthracene from non-polar solvent (heptane). Lipids macrocomponents such as myristic acid and vegetable oil do not decrease the dynamic adsorption capacity and recovery of the model polycyclic aromatic hydrocarbon (PAH) on SiO2-Ant. It was demonstrated that π-π stacking interaction with the analyte determine the selectivity of SiO2-Ant towards of anthracene. This makes SiO2-Ant attractive for selective preconcentration of PAHs from high lipid content objects, such as vegetable oils.

scholarly journals Synthesis, Characterization and Textural Analysis of Functionalized Mesoporous Silica Using Sodium Silicate as Precursor and Silicone Surfactant as Template

2014 ◽  
Vol 11 (2) ◽  
pp. 419-428
Author(s):  
Baghdad Science Journal
Keyword(s):  
Mesoporous Silica ◽  
Sodium Silicate ◽  
Nitrogen Adsorption ◽  
Average Diameter ◽  
Functionalized Silica ◽  
Average Pore ◽  
Force Microscopy ◽  
Functionalized Mesoporous Silica ◽  
One Step ◽  
Adsorption Desorption

Three mesoporous silica with different functional group were prepared by one-step synthesis based on the simultaneous hydrolysis and condensation of sodium silicate with organo - silane in the presence of template surfactant polydimethylsiloxane - polyethyleneoxide (PDMS - PEO). The prepared materials were characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), atomic force microscopy (AFM) and nitrogen adsorption/desorption experiments. The results indicate that the preparation of methyl and phenyl functionalized silica were successful and the mass of methyl and phenyl groups bonded to the silica structure are 15, 38 mmol per gram silica. The average diameter of the silica particles are 103.51, 167.25 , and 86.41 nm while the average pore diameter are 6.7, 16.4, and 2.7 nm for unfunctionalized, methyl, and phenyl functionalized silica respectively.

scholarly journals The Design of Anionic Surfactant-Based Amino-Functionalized Mesoporous Silica Nanoparticles and their Application in Transdermal Drug Delivery

Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1035
Author(s):  
Aliyah Almomen ◽  
Ahmed M. El-Toni ◽  
Mohammed Badran ◽  
Adel Alhowyan ◽  
Mohd Abul Kalam ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Anionic Surfactant ◽  
Mesoporous Silica Nanoparticles ◽  
Synergetic Effect ◽  
Melanoma Cells ◽  
Skin Permeability ◽  
Loading Capacity ◽  
Structure Directing Agent ◽  
Functionalized Mesoporous Silica

Melanoma remains the most lethal form of skin cancer and most challenging to treat despite advances in the oncology field. Our work describes the utilization of nanotechnology to target melanoma locally in an attempt to provide an advanced and efficient quality of therapy. Amino-functionalized mesoporous silica nanoparticles (MSN-NH2) were developed in situ through the utilization of anionic surfactant and different volumes of 3-aminopropyltriethoxysilane (APTES) as a co-structure directing agent (CSDA). Prepared particles were characterized for their morphology, particles size, 5-flurouracol (5-FU) and dexamethasone (DEX) loading capacity and release, skin penetration, and cytotoxicity in vitro in HT-144 melanoma cells. Results of transmission electron microscopy (TEM) and nitrogen adsorption–desorption isotherm showed that using different volumes of APTES during the functionalization process had an impact on the internal and external morphology of the particles, as well as particle size. However, changing the volume of APTES did not affect the diameter of formed mesochannels, which was about 4 nm. MSN-NH2 showed a relatively high loading capacity of 5-FU (12.6 ± 5.5) and DEX (44.72 ± 4.21) when using drug: MSN-NH2 ratios of 5:1 for both drugs. The release profile showed that around 83% of 5-FU and 21% of DEX were released over 48 h in pH 7.4. The skin permeability study revealed that enhancement ratio of 5-Fu and DEX using MSN-NH2 were 4.67 and 5.68, respectively, relative to their free drugs counterparts. In addition, the accumulation of drugs in skin layers where melanoma cells usually reside were enhanced approximately 10 times with 5-FU and 5 times with DEX when delivering drugs using MSN-NH2 compared to control. MSN-NH2 alone was nontoxic to melanoma cells when incubated for 48 h in the range of 0 to 468 µg/mL. The combination of 5-FU MSN-NH2 and DEX MSN-NH2 showed significant increase in toxicity compared to their free dug counterparts and exhibited a synergetic effect as well as the ability to circumvent DEX induced 5-FU resistance in melanoma cells.

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