Fast and facile preparation of PEGylated graphene from graphene oxide by lysosome targeting delivery of photosensitizer to efficiently enhance photodynamic therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (71) ◽  
pp. 57725-57734 ◽  
Author(s):  
Yiping Zeng ◽  
Zhangyou Yang ◽  
Shenglin Luo ◽  
Hong Li ◽  
Cong Liu ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Photodynamic Therapy ◽  
Polyethylene Glycol ◽  
Mass Production ◽  
Production Method ◽  
Targeting Delivery ◽  
Branched Polyethylenimine ◽  
Facile Preparation

A fast, facile and mass production method was reported to obtain stable and disperse polyethylene glycol (PEG) modified nanographene (NGO-PEG). Branched polyethylenimine (BPEI) was used to modify the NGO-PEG (NGO-PEG-BPEI) for further application.

scholarly journals Polyethylene Glycol Functionalized Graphene Oxide Nanoparticles Loaded with Nigella sativa Extract: A Smart Antibacterial Therapeutic Drug Delivery System

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3067
Author(s):  
Mustafa A. Jihad ◽  
Farah T. M. Noori ◽  
Majid S. Jabir ◽  
Salim Albukhaty ◽  
Faizah A. AlMalki ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Grain Size ◽  
Cell Wall ◽  
Graphene Oxide ◽  
Polyethylene Glycol ◽  
Nucleic Acid ◽  
Drug Delivery System ◽  
Delivery System ◽  
Nigella Sativa ◽  
Seed Extract

Flaky graphene oxide (GO) nanoparticles (NPs) were synthesized using Hummer’s method and then capped with polyethylene glycol (PEG) by an esterification reaction, then loaded with Nigella sativa (N. sativa) seed extract. Aiming to investigate their potential use as a smart drug delivery system against Staphylococcus aureus and Escherichia coli, the spectral and structural characteristics of GO-PEG NPs were comprehensively analyzed by XRD, AFM, TEM, FTIR, and UV- Vis. XRD patterns revealed that GO-PEG had different crystalline structures and defects, as well as a higher interlayer spacing. AFM results showed GONPs with the main grain size of 24.41 nm, while GONPs–PEG revealed graphene oxide aggregation with the main grain size of 287.04 nm after loading N. sativa seed extract, which was verified by TEM examination. A strong OH bond appeared in FTIR spectra. Furthermore, UV- Vis absorbance peaks at (275, 284, 324, and 327) nm seemed to be correlated with GONPs, GO–PEG, N. sativa seed extract, and GO –PEG- N. sativa extract. The drug delivery system was observed to destroy the bacteria by permeating the bacterial nucleic acid and cytoplasmic membrane, resulting in the loss of cell wall integrity, nucleic acid damage, and increased cell-wall permeability.

Green and facile preparation of graphene/resveratrol/polyaniline composites for high-performance supercapacitors

2021 ◽  
Vol 45 (7) ◽  
pp. 3581-3588
Author(s):  
Zhaokun Wang ◽  
Licong Jiang ◽  
Hongwei Pan ◽  
Yongyin Cui ◽  
Chengzhong Zong
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
High Performance ◽  
Environmentally Friendly ◽  
Reduced Graphene ◽  
Facile Preparation ◽  
Polyaniline Composites

A novel and environmentally-friendly resveratrol (RA) was used as an effective reagent for the preparation of reduced graphene oxide (rGO).

Graphene oxide/polyethylene glycol aerogel reinforced with grape seed extracts as wound dressing

2021 ◽  
Author(s):  
Jessica Borges-Vilches ◽  
Javiera Poblete ◽  
Fernando Gajardo ◽  
Claudio Aguayo ◽  
Katherina Fernández
Keyword(s):  
Graphene Oxide ◽  
Polyethylene Glycol ◽  
Wound Dressing ◽  
Grape Seed ◽  
Grape Seed Extracts ◽  
Seed Extracts

Layer by layer assembled functionalized graphene oxide-based polymer brushes for superlubricity on steel-steel tribocontact

Soft Matter ◽  
2021 ◽  
Author(s):  
Suprakash Samanta ◽  
Rashmi Ranjan Sahoo
Keyword(s):  
Graphene Oxide ◽  
Nucleophilic Addition ◽  
Polymer Brushes ◽  
Addition Reaction ◽  
Layer By Layer ◽  
Functionalized Graphene ◽  
Covalent Functionalization ◽  
Functionalized Graphene Oxide ◽  
Nucleophilic Addition Reaction ◽  
Branched Polyethylenimine

Present study demonstrates a simple and multistep approach for the preparation of covalent functionalization of chemically prepared graphene oxide (GO) by branched polyethylenimine (PEI) through nucleophilic addition reaction to prepare...

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