Tumor targeted gold nanoparticles for FRET-based tumor imaging and light responsive on-demand drug release

2015 ◽  
Vol 3 (41) ◽  
pp. 8065-8069 ◽  
Author(s):  
Kai Han ◽  
Jing-Yi Zhu ◽  
Shi-Bo Wang ◽  
Zi-Hao Li ◽  
Si-Xue Cheng ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Photodynamic Therapy ◽  
Side Effects ◽  
Drug Release ◽  
Tumor Imaging ◽  
On Demand

Multifunctional AuNPs for MMP-2 responsive tumor imaging and on-demand drug release were designed. A good chemotherapy and photodynamic therapy combination with minimized side effects was realized.

scholarly journals Photodynamic therapy-triggered on-demand drug release from ROS-responsive core-cross-linked micelles toward synergistic anti-cancer treatment

Nano Research ◽  
2019 ◽  
Vol 12 (5) ◽  
pp. 999-1008 ◽  
Author(s):  
Yongjuan Li ◽  
Jian Hu ◽  
Xun Liu ◽  
Yong Liu ◽  
Shixian Lv ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Drug Release ◽  
Cancer Treatment ◽  
On Demand ◽  
Anti Cancer

Photodynamic therapy-mediated remote control of chemotherapy toward synergistic anticancer treatment

Nanoscale ◽  
2018 ◽  
Vol 10 (30) ◽  
pp. 14554-14562 ◽  
Author(s):  
Yongjuan Li ◽  
Shixian Lv ◽  
Ziyuan Song ◽  
Juanjuan Dang ◽  
Xudong Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Remote Control ◽  
Cancer Therapy ◽  
Drug Release ◽  
Stimuli Responsive ◽  
On Demand ◽  
Release Property ◽  
Anticancer Treatment

Stimuli-responsive nanomedicine (NM) with an on-demand drug release property has demonstrated promising utility toward cancer therapy.

Smart mesoporous silica nanoparticles gated by pillararene-modified gold nanoparticles for on-demand cargo release

2016 ◽  
Vol 52 (95) ◽  
pp. 13775-13778 ◽  
Author(s):  
Xin Wang ◽  
Li-Li Tan ◽  
Xi Li ◽  
Nan Song ◽  
Zheng Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Release ◽  
On Demand

A new drug delivery system, based on mesoporous silica nanoparticles gated by carboxylatopillar[5]arene-modified gold nanoparticles, has been fabricated for controlled drug release.

Tumor pH-triggered “charge conversion” nanocarriers with on-demand drug release for precise cancer therapy

2020 ◽  
Vol 8 (40) ◽  
pp. 9351-9361
Author(s):  
Bo-Ai Ma ◽  
Chun-Yang Sun
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Drug Release ◽  
X Ray ◽  
On Demand ◽  
Tumor Ph

The pHe-triggered “charge conversion” nanocarriers were developed for combined X-ray-induced photodynamic therapy (X-PDT) and hypoxia-activated chemotherapy.

ROS‐Responsive Camptothecin Prodrug Nanoparticles for On‐Demand Drug Release and Combination of Chemotherapy and Photodynamic Therapy

2020 ◽  
Vol 30 (52) ◽  
pp. 2005918
Author(s):  
Bingyang Chu ◽  
Ying Qu ◽  
Xinlong He ◽  
Ying Hao ◽  
Chengli Yang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Drug Release ◽  
On Demand

NIR-sensitive UCNP@mSiO2 nanovehicles for on-demand drug release and photodynamic therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (31) ◽  
pp. 26479-26489 ◽  
Author(s):  
Ting Zhang ◽  
Huiming Lin ◽  
Liru Cui ◽  
Na An ◽  
Ruihan Tong ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Drug Release ◽  
Cancer Cell ◽  
On Demand ◽  
Specific Cytotoxicity

The synthesis of UCNP@mSiO2/HA nanovehicle reveals the NIR-triggered chemotherapy/PDT as well as the enhanced specific cytotoxicity to cancer cell.

Recent Advances in Efficacy of Using Doxorubicin Gold Nanoparticles for Chemo-, Radio-, Photothermal, and Photodynamic therapy

2021 ◽  
Vol 18 ◽  
Author(s):  
Niloufar Choubdar ◽  
Sara Avizheh ◽  
Seyed Ali Karimifard
Keyword(s):  
Gold Nanoparticles ◽  
Photodynamic Therapy ◽  
Side Effects ◽  
Water Solubility ◽  
High Water ◽  
Multi Drug Resistance ◽  
Therapeutic Drug ◽  
Target Cells ◽  
Recent Advances ◽  
Effective Cancer Therapy

: Nanoparticles (NPs) have been widely used in drug delivery systems specifically for chemo-, radio-, photothermal, and photodynamic therapy. Due to the lack of selectivity toward tumor cells the main target in therapies is to deliver drugs to cancer cells to reduce side effects. Gold nanoparticles (AuNPs) have been described as “promising nanocarriers for therapeutics” due to many properties such as low inherent toxicity, high water solubility and biocompatibility. Many research groups have focused on taking advantage of two or more therapies simultaneously to have increased efficacy using a lower dosage of the therapeutic drug and reduced multi drug resistance (MDR). Alternatively, doxorubicin (Dox) modification has been used as a strategy for increased selectivity toward target cells. Over the years, many studies have been performed on NPs to eliminate side effects using polymers, peptides, proteins, DNA, metallic NPs, microgels, and hydrogels on drug carrierse. In this review, recent advances of using Dox-AuNPs for chemo-, radio-, photothermal, photodynamic and combination therapy are briefly discussed, and we highlight recent progression in the application of Dox-AuNPs for effective cancer therapy.

Cancer cell membrane-coated nanogels as redox/pH dual-responsive drug carrier for tumor-targeted therapy

2021 ◽  
Author(s):  
Junjie Deng ◽  
Weide Xu ◽  
Jilong Wang ◽  
Qinghua Li ◽  
Chenghu Wu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Therapy ◽  
Side Effects ◽  
Drug Release ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Drug Carrier ◽  
On Demand ◽  
Dual Responsive

Nanocarriers have shown great advantages in increasing the efficiency of drug delivery and reducing the side effects. However, the lack of targeting and on-demand drug release will seriously limit their...

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