Towards improved magnetic fluid hyperthermia: major-loops to diminish variations in local heating

Hyperthermia therapy for cancer has attracted much attention nowadays. The study on the heat transfer in the magnetic fluid and the tumor is crucial for the successful application of magnetic fluid hyperthermia (MFH). Water-based Fe3O4 magnetic fluid is expected to be a most appropriate candidate for MFH due to the good biocompatibility, high saturation magnetization, super-paramagnetization and high chemical stability. In this paper, we explore the heat generation and transfer in magnetic fluid which is placed under an AC magnetic field. It is found that the amplitude and the frequency of alternating magnetic field, particle size and volume fraction have a pronounce influence on maximum temperature of hyperthermia.

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Applications of Oscillatory Flow of Magnetic Fluid as Active Damper and Actuator

International Journal of Modern Physics B ◽

10.1142/s0217979299002332 ◽

1999 ◽

Vol 13 (14n16) ◽

pp. 2213-2220 ◽

Cited By ~ 1

Author(s):

Shinichi Kamiyama

Keyword(s):

Magnetic Field ◽

Magnetic Fluid ◽

Applied Magnetic Field ◽

Oscillatory Flow ◽

Mass System ◽

Active Damper

Study on the control of vibration of a spring-mass system attached to a piston immersed in a magnetic fluid by controlling the applied magnetic field is conducted theoretically and experimentally to develop the magnetic fluid active damper and actuator.

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Effect of an applied magnetic field on sloshing pressure in a magnetic fluid

Journal of Physics Conference Series ◽

10.1088/1742-6596/412/1/012018 ◽

2013 ◽

Vol 412 ◽

pp. 012018 ◽

Cited By ~ 2

Author(s):

S Kaneko ◽

T Ishiyama ◽

T Sawada

Keyword(s):

Magnetic Field ◽

Magnetic Fluid ◽

Applied Magnetic Field ◽

Sloshing Pressure

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Tunable Characteristics and Mechanism Analysis of the Magnetic Fluid Refractive Index With Applied Magnetic Field

IEEE Transactions on Magnetics ◽

10.1109/tmag.2014.2310710 ◽

2014 ◽

Vol 50 (8) ◽

pp. 1-5 ◽

Cited By ~ 47

Author(s):

Yong Zhao ◽

Di Wu ◽

Ri-Qing Lv ◽

Yu Ying

Keyword(s):

Magnetic Field ◽

Refractive Index ◽

Magnetic Fluid ◽

Applied Magnetic Field ◽

Mechanism Analysis

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MAGNETIC FLUID HYPERTHERMIA IN A CYLINDRICAL GEL CONTAINS WATER FLOW

Journal of Mechanics in Medicine and Biology ◽

10.1142/s0219519415500888 ◽

2015 ◽

Vol 15 (05) ◽

pp. 1550088 ◽

Cited By ~ 3

Author(s):

MORTEZA HEYDARI ◽

MEHRDAD JAVIDI ◽

MOHAMMAD MAHDI ATTAR ◽

ALIREZA KARIMI ◽

MAHDI NAVIDBAKHSH ◽

...

Keyword(s):

Magnetic Field ◽

Experimental Data ◽

Fluid Flow ◽

Magnetic Fluid ◽

Blood Perfusion ◽

Temperature Function ◽

Magnetic Fluid Hyperthermia ◽

Frequency Magnetic Field ◽

Complicated Part ◽

Cancerous Cells

In magnetic fluid hyperthermia (MFH), nanoparticles are injected into a diseased tissue and then subjected to an alternating high frequency magnetic field. The produced heat may have a key asset to destroy the cancerous cells. The blood flow in a tissue is considered as the most complicated part of the MFH which should be taken into account in the analysis of the MFH. This study was aimed to perform an experimental study to investigate the heat transfer of agar gel which contains fluid flow. Fe 3 O 4 as a nanoparticle was injected into the center of a cylindrical gel. It was also embedded with other cylindrical gels and subjected to an alternating magnetic field of 7.3 (kA/m) and a frequency of 50 (kHz) for 3600 (s). The temperature of the gel was measured at three points. The temperature distribution was measured via the experimental data. Moreover, specific absorption rate (SAR) was quantified with time differential temperature function at t = 0 by means of experimental data. Finite element method (FEM) was employed to establish a model to validate the SAR function. Results revealed the effects of fluid flow and accuracy of the SAR function for heat production in gel. The proposed function have implications in hyperthermia studies as a heat generation source. Finally, the condition of experimental setup was simulated to find the blood perfusion.

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