scholarly journals Carbon Based Nanodots in Early Diagnosis of Cancer

2021 ◽  
Vol 9 ◽  
Author(s):  
Gurpal Singh ◽  
Harinder Kaur ◽  
Akanksha Sharma ◽  
Joga Singh ◽  
Hema Kumari Alajangi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Early Stage ◽  
Imaging Techniques ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Diagnostic Methods ◽  
Early Diagnosis Of Cancer ◽  
Successful Treatment Outcome ◽  
Wide Range ◽  
Carbon Based

Detection of cancer at an early stage is one of the principal factors associated with successful treatment outcome. However, current diagnostic methods are not capable of making sensitive and robust cancer diagnosis. Nanotechnology based products exhibit unique physical, optical and electrical properties that can be useful in diagnosis. These nanotech-enabled diagnostic representatives have proved to be generally more capable and consistent; as they selectively accumulated in the tumor site due to their miniscule size. This article rotates around the conventional imaging techniques, the use of carbon based nanodots viz Carbon Quantum Dots (CQDs), Graphene Quantum Dots (GQDs), Nanodiamonds, Fullerene, and Carbon Nanotubes that have been synthesized in recent years, along with the discovery of a wide range of biomarkers to identify cancer at early stage. Early detection of cancer using nanoconstructs is anticipated to be a distinct reality in the coming years.

scholarly journals Carbon-based quantum particles: an electroanalytical and biomedical perspective

2019 ◽  
Vol 48 (15) ◽  
pp. 4281-4316 ◽  
Author(s):  
Khadijeh Nekoueian ◽  
Mandana Amiri ◽  
Mika Sillanpää ◽  
Frank Marken ◽  
Rabah Boukherroub ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Quantum Confinement ◽  
Quantum Confinement Effect ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Confinement Effect ◽  
Spherical Carbon ◽  
Quantum Particles ◽  
Carbon Based

Carbon-based quantum particles, especially spherical carbon quantum dots (CQDs) and nanosheets like graphene quantum dots (GQDs), are an emerging class of quantum dots with unique properties owing to their quantum confinement effect.

scholarly journals Carbon-Based Quantum Dots for Supercapacitors: Recent Advances and Future Challenges

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 91
Author(s):  
Fitri Aulia Permatasari ◽  
Muhammad Alief Irham ◽  
Satria Zulkarnaen Bisri ◽  
Ferry Iskandar
Keyword(s):  
Quantum Dots ◽  
High Performance ◽  
Quantum Confinement Effect ◽  
Graphene Quantum Dots ◽  
High Energy ◽  
Carbon Quantum Dots ◽  
High Energy Density ◽  
Research Progress ◽  
Future Challenges ◽  
Carbon Based

Carbon-based Quantum dots (C-QDs) are carbon-based materials that experience the quantum confinement effect, which results in superior optoelectronic properties. In recent years, C-QDs have attracted attention significantly and have shown great application potential as a high-performance supercapacitor device. C-QDs (either as a bare electrode or composite) give a new way to boost supercapacitor performances in higher specific capacitance, high energy density, and good durability. This review comprehensively summarizes the up-to-date progress in C-QD applications either in a bare condition or as a composite with other materials for supercapacitors. The current state of the three distinct C-QD families used for supercapacitors including carbon quantum dots, carbon dots, and graphene quantum dots is highlighted. Two main properties of C-QDs (structural and electrical properties) are presented and analyzed, with a focus on the contribution to supercapacitor performances. Finally, we discuss and outline the remaining major challenges and future perspectives for this growing field with the hope of stimulating further research progress.

scholarly journals Recent Developments in Carbon Quantum Dots: Properties, Fabrication Techniques, and Bio-Applications

Processes ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 388
Author(s):  
Rehan M. El-Shabasy ◽  
Mohamed Farouk Elsadek ◽  
Badreldin Mohamed Ahmed ◽  
Mohamed Fawzy Farahat ◽  
Khaled N. Mosleh ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Green Synthesis ◽  
Graphene Quantum Dots ◽  
Carbon Sources ◽  
Carbon Quantum Dots ◽  
Synthesis Methods ◽  
Wide Range ◽  
Recent Developments ◽  
Potential Applications ◽  
Harsh Conditions

Carbon dots have gained tremendous interest attributable to their unique features. Two approaches are involved in the fabrication of quantum dots (Top-down and Bottom-up). Most of the synthesis methods are usually multistep, required harsh conditions, and costly carbon sources that may have a toxic effect, therefore green synthesis is more preferable. Herein, the current review presents the green synthesis of carbon quantum dots (CQDs) and graphene quantum dots (GQDs) that having a wide range of potential applications in bio-sensing, cellular imaging, and drug delivery. However, some drawbacks and limitations are still unclear. Other biomedical and biotechnological applications are also highlighted.

Recent advances in carbon-based dots for electroanalysis

The Analyst ◽  
2016 ◽  
Vol 141 (9) ◽  
pp. 2619-2628 ◽  
Author(s):  
Ying Yulong ◽  
Peng Xinsheng
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Recent Advances ◽  
Carbon Based

Graphene quantum dots (GQDs) and carbon quantum dots (CQDs) demonstrate unique properties in the electroanalysis field, including electroresistance, electrochemiluminescence, electrochemical and photoelectrochemical sensors.

Sensing applications of luminescent carbon based dots

The Analyst ◽  
2015 ◽  
Vol 140 (22) ◽  
pp. 7468-7486 ◽  
Author(s):  
Yongqiang Dong ◽  
Jianhua Cai ◽  
Xu You ◽  
Yuwu Chi
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Luminescence Properties ◽  
Sensing Applications ◽  
Carbon Based

Carbon based dots (CDs) including carbon quantum dots and graphene quantum dots exhibit unique luminescence properties, such as photoluminescence (PL), chemiluminescence (CL) and electrochemiluminescence (ECL).

scholarly journals N-Doped Carbon Quantum Dots as Fluorescent Bioimaging Agents

Crystals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 789
Author(s):  
Shih-Fu Ou ◽  
Ya-Yun Zheng ◽  
Sin-Jen Lee ◽  
Shyi-Tien Chen ◽  
Chien-Hui Wu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Carbon Nanomaterials ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Fluorescence Characteristics ◽  
And Staphylococcus Aureus

Graphene quantum dots, carbon nanomaterials with excellent fluorescence characteristics, are advantageous for use in biological systems owing to their small size, non-toxicity, and biocompatibility. We used the hydrothermal method to prepare functional N-doped carbon quantum dots (N-CQDs) from 1,3,6-trinitropyrene and analyzed their ability to fluorescently stain various bacteria. Our results showed that N-CQDs stain the cell septa and membrane of the Gram-negative bacteria Escherichia coli, Salmonellaenteritidis, and Vibrio parahaemolyticus and the Gram-positive bacteria Bacillus subtilis, Listeria monocytogenes, and Staphylococcus aureus. The optimal concentration of N-CQDs was approximately 500 ppm for Gram-negative bacteria and 1000 ppm for Gram-positive bacteria, and the exposure times varied with bacteria. N-Doped carbon quantum dots have better light stability and higher photobleaching resistance than the commercially available FM4-64. When excited at two different wavelengths, N-CQDs can emit light of both red and green wavelengths, making them ideal for bioimaging. They can also specifically stain Gram-positive and Gram-negative bacterial cell membranes. We developed an inexpensive, relatively easy, and bio-friendly method to synthesize an N-CQD composite. Additionally, they can serve as a universal bacterial membrane-staining dye, with better photobleaching resistance than commercial dyes.

scholarly journals Formation of Carbon Quantum Dots via Hydrothermal Carbonization: Investigate the Effect of Precursors

Energies ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 986
Author(s):  
Md Rifat Hasan ◽  
Nepu Saha ◽  
Thomas Quaid ◽  
M. Toufiq Reza
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Microcrystalline Cellulose ◽  
Uv Light ◽  
Synthesis Method ◽  
Hydrothermal Carbonization ◽  
Carbon Quantum Dots ◽  
Medical Diagnostics ◽  
Particle Size Range ◽  
Wide Range

Carbon quantum dots (CQDs) are nanomaterials with a particle size range of 2 to 10 nm. CQDs have a wide range of applications such as medical diagnostics, bio-imaging, biosensors, coatings, solar cells, and photocatalysis. Although the effect of various experimental parameters, such as the synthesis method, reaction time, etc., have been investigated, the effect of different feedstocks on CQDs has not been studied yet. In this study, CQDs were synthesized from hydroxymethylfurfural, furfural, and microcrystalline cellulose via hydrothermal carbonization at 220 °C for 30 min of residence time. The produced CQDs showed green luminescence behavior under the short-wavelength UV light. Furthermore, the optical properties of CQDs were investigated using ultraviolet-visible spectroscopy and emission spectrophotometer, while the morphology and chemical bonds of CQDs were investigated using transmission electron microscopy and Fourier-transform infrared spectroscopy, respectively. Results showed that all CQDs produced from various precursors have absorption and emission properties but these optical properties are highly dependent on the type of precursor. For instance, the mean particle sizes were 6.36 ± 0.54, 5.35 ± 0.56, and 3.94 ± 0.60 nm for the synthesized CQDs from microcrystalline cellulose, hydroxymethylfurfural, and furfural, respectively, which appeared to have similar trends in emission intensities. In addition, the synthesized CQDs experienced different functionality (e.g., C=O, O-H, C-O) resulting in different absorption behavior.

scholarly journals Organic dots (O-dots) for theranostic applications: preparation and surface engineering

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Surface Engineering ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Cargo Delivery ◽  
Bio Imaging ◽  
Theranostic Applications

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.

Microplasma Band Structure Engineering in Graphene Quantum Dots for Sensitive and Wide-Range pH Sensing

2021 ◽  
Author(s):  
Darwin Kurniawan ◽  
Bai Amutha Anjali ◽  
Owen Setiawan ◽  
Kostya Ken Ostrikov ◽  
Yongchul G. Chung ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Band Structure ◽  
Graphene Quantum Dots ◽  
Ph Sensing ◽  
Wide Range ◽  
Structure Engineering

scholarly journals Synthesis and Properties of Nitrogen-Doped Carbon Quantum Dots Using Lactic Acid as Carbon Source

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 466
Author(s):  
Kaixin Chang ◽  
Qianjin Zhu ◽  
Liyan Qi ◽  
Mingwei Guo ◽  
Woming Gao ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Lactic Acid ◽  
Fluorescence Quenching ◽  
Functional Groups ◽  
Fluorescence Intensity ◽  
Carbon Quantum Dots ◽  
Nitrogen Doped ◽  
Ph Values ◽  
Wide Range ◽  
Nitrogen Doped Carbon

Nitrogen-doped carbon quantum dots (N-CQDs) were synthesized in a one-step hydrothermal technique utilizing L-lactic acid as that of the source of carbon and ethylenediamine as that of the source of nitrogen, and were characterized using dynamic light scattering, X-ray photoelectron spectroscopy ultraviolet-visible spectrum, Fourier-transformed infrared spectrum, high-resolution transmission electron microscopy, and fluorescence spectrum. The generated N-CQDs have a spherical structure and overall diameters ranging from 1–4 nm, and their surface comprises specific functional groups such as amino, carboxyl, and hydroxyl, resulting in greater water solubility and fluorescence. The quantum yield of N-CQDs (being 46%) is significantly higher than that of the CQDs synthesized from other biomass in literatures. Its fluorescence intensity is dependent on the excitation wavelength, and N-CQDs release blue light at 365 nm under ultraviolet light. The pH values may impact the protonation of N-CQDs surface functional groups and lead to significant fluorescence quenching of N-CQDs. Therefore, the fluorescence intensity of N-CQDs is the highest at pH 7.0, but it decreases with pH as pH values being either more than or less than pH 7.0. The N-CQDs exhibit high sensitivity to Fe3+ ions, for Fe3+ ions would decrease the fluorescence intensity of N-CQDs by 99.6%, and the influence of Fe3+ ions on N-CQDs fluorescence quenching is slightly affected by other metal ions. Moreover, the fluorescence quenching efficiency of Fe3+ ions displays an obvious linear relationship to Fe3+ concentrations in a wide range of concentrations (up to 200 µM) and with a detection limit of 1.89 µM. Therefore, the generated N-CQDs may be utilized as a robust fluorescence sensor for detecting pH and Fe3+ ions.

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