scholarly journals The quest to 3D print body parts

2016 ◽  
Vol 38 (4) ◽  
pp. 24-27 ◽  
Author(s):  
Anthony Atala ◽  
Karen Richardson

From engineering and manufacturing to art and education, 3D printing is helping to drive innovation in many different fields. Medicine is no exception. The technology is being used to print prosthetic limbs and to fabricate patient-specific models of body parts for surgeons to use as guides during reconstructive surgery. A 3D printed titanium jawbone has been implanted in a patient, as has a tailormade, bioresorbable tracheal splint that saved a baby's life.

Polymers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 2518
Author(s):  
Nunzio Cennamo ◽  
Lorena Saitta ◽  
Claudio Tosto ◽  
Francesco Arcadio ◽  
Luigi Zeni ◽  
...  

In this work, a novel approach to realize a plasmonic sensor is presented. The proposed optical sensor device is designed, manufactured, and experimentally tested. Two photo-curable resins are used to 3D print a surface plasmon resonance (SPR) sensor. Both numerical and experimental analyses are presented in the paper. The numerical and experimental results confirm that the 3D printed SPR sensor presents performances, in term of figure of merit (FOM), very similar to other SPR sensors made using plastic optical fibers (POFs). For the 3D printed sensor, the measured FOM is 13.6 versus 13.4 for the SPR-POF configuration. The cost analysis shows that the 3D printed SPR sensor can be manufactured at low cost (∼15 €) that is competitive with traditional sensors. The approach presented here allows to realize an innovative SPR sensor showing low-cost, 3D-printing manufacturing free design and the feasibility to be integrated with other optical devices on the same plastic planar support, thus opening undisclosed future for the optical sensor systems.


2021 ◽  
Vol 7 ◽  
Author(s):  
Jasamine Coles-Black ◽  
Damien Bolton ◽  
Jason Chuen

Introduction: 3D printed patient-specific vascular phantoms provide superior anatomical insights for simulating complex endovascular procedures. Currently, lack of exposure to the technology poses a barrier for adoption. We offer an accessible, low-cost guide to producing vascular anatomical models using routine CT angiography, open source software packages and a variety of 3D printing technologies.Methods: Although applicable to all vascular territories, we illustrate our methodology using Abdominal Aortic Aneurysms (AAAs) due to the strong interest in this area. CT aortograms acquired as part of routine care were converted to representative patient-specific 3D models, and then printed using a variety of 3D printing technologies to assess their material suitability as aortic phantoms. Depending on the technology, phantoms cost $20–$1,000 and were produced in 12–48 h. This technique was used to generate hollow 3D printed thoracoabdominal aortas visible under fluoroscopy.Results: 3D printed AAA phantoms were a valuable addition to standard CT angiogram reconstructions in the simulation of complex cases, such as short or very angulated necks, or for positioning fenestrations in juxtarenal aneurysms. Hollow flexible models were particularly useful for device selection and in planning of fenestrated EVAR. In addition, these models have demonstrated utility other settings, such as patient education and engagement, and trainee and anatomical education. Further study is required to establish a material with optimal cost, haptic and fluoroscopic fidelity.Conclusion: We share our experiences and methodology for developing inexpensive 3D printed vascular phantoms which despite material limitations, successfully mimic the procedural challenges encountered during live endovascular surgery. As the technology continues to improve, 3D printed vascular phantoms have the potential to disrupt how endovascular procedures are planned and taught.


Symbrachydactyly is a genetical problem occurred to newborn where the newborn experienced underdeveloped or shorten fingers. This condition will limit their normal as even a simple task of holding an item or pushing a button. A device is needed to help them gain a better life. The aim of this project is to fabricate a customized prosthesis hand using 3D printing technology at minimum cost. The proposed prosthetic was not embedded with any electrical component. The patient can only use the wrist to control the prosthetic part which is the prosthetic fingers. The prosthetic hand was also being developed with the patient specific features, which the initial design stage was adapted from a person’s hand geometry using a 3D scanner. Next the model of the prosthesis was analyzed computationally to predict the performance of the product. Different material properties are considered in the analysis to present Polylactic Acid (PLA) and Acrylonitrile Butadiene Styrene (ABS) materials. Then, the prosthesis was fabricated using the 3D printing. The results suggested that PLA material indicated better findings and further be fabricated.


2018 ◽  
Vol 15 (3) ◽  
pp. 341-349 ◽  
Author(s):  
Alexander I Evins ◽  
John Dutton ◽  
Sayem S Imam ◽  
Amal O Dadi ◽  
Tao Xu ◽  
...  

Abstract BACKGROUND Currently, implantation of patient-specific cranial prostheses requires reoperation after a period for design and formulation by a third-party manufacturer. Recently, 3-dimensional (3D) printing via fused deposition modeling has demonstrated increased ease of use, rapid production time, and significantly reduced costs, enabling expanded potential for surgical application. Three-dimensional printing may allow neurosurgeons to remove bone, perform a rapid intraoperative scan of the opening, and 3D print custom cranioplastic prostheses during the remainder of the procedure. OBJECTIVE To evaluate the feasibility of using a commercially available 3D printer to develop and produce on-demand intraoperative patient-specific cranioplastic prostheses in real time and assess the associated costs, fabrication time, and technical difficulty. METHODS Five different craniectomies were each fashioned on 3 cadaveric specimens (6 sides) to sample regions with varying topography, size, thickness, curvature, and complexity. Computed tomography-based cranioplastic implants were designed, formulated, and implanted. Accuracy of development and fabrication, as well as implantation ability and fit, integration with exiting fixation devices, and incorporation of integrated seamless fixation plates were qualitatively evaluated. RESULTS All cranioprostheses were successfully designed and printed. Average time for design, from importation of scan data to initiation of printing, was 14.6 min and average print time for all cranioprostheses was 108.6 min. CONCLUSION On-demand 3D printing of cranial prostheses is a simple, feasible, inexpensive, and rapid solution that may help improve cosmetic outcomes; significantly reduce production time and cost—expanding availability; eliminate the need for reoperation in select cases, reducing morbidity; and has the potential to decrease perioperative complications including infection and resorption.


Author(s):  
Chia-An Wu ◽  
Andrew Squelch ◽  
Zhonghua Sun

Aim: To determine a printing material that has both elastic property and radiology equivalence close to real aorta for simulation of endovascular stent graft repair of aortic dissection. Background: With the rapid development of three-dimensional (3D) printing technology, a patient-specific 3D printed model is able to help surgeons to make better treatment plan for Type B aortic dissection patients. However, the radiological properties of most 3D printing materials have not been well characterized. This study aims to investigate the appropriate materials for printing human aorta with mechanical and radiological properties similar to the real aortic computed tomography (CT) attenuation. Objective: Quantitative assessment of CT attenuation of different materials used in 3D printed models of aortic dissection for developing patient-specific 3D printed aorta models to simulate type B aortic dissection. Method: A 25-mm length of aorta model was segmented from a patient’s image dataset with diagnosis of type B aortic dissection. Four different elastic commercial 3D printing materials, namely Agilus A40 and A50, Visijet CE-NT A30 and A70 were selected and printed with different hardness. Totally four models were printed out and conducted CT scanned twice on a 192-slice CT scanner using the standard aortic CT angiography protocol, with and without contrast inside the lumen.Five reference points with region of interest (ROI) of 1.77 mm2 were selected at the aortic wall and intimal flap and their Hounsfield units (HU) were measured and compared with the CT attenuation of original CT images. The comparison between the patient’s aorta and models was performed through a paired-sample t-test to determine if there is any significant difference. Result: The mean CT attenuation of aortic wall of the original CT images was 80.7 HU. Analysis of images without using contrast medium showed that the material of Agilus A50 produced the mean CT attenuation of 82.6 HU, which is similar to that of original CT images. The CT attenuation measured at images acquired with other three materials was significantly lower than that of original images (p<0.05). After adding contrast medium, Visijet CE-NT A30 had an average CT attenuation of 90.6 HU, which is close to that of the original images with statistically significant difference (p>0.05). In contrast, the CT attenuation measured at images acquired with other three materials (Agilus A40, A50 and Visiject CE-NT A70) was 129 HU, 135 HU and 129.6 HU, respectively, which is significantly higher than that of original CT images (p<0.05). Conclusion: Both Visijet CE-NT and Agilus have tensile strength and elongation close to real patient’s tissue properties producing similar CT attenuation. Visijet CE-NT A30 is considered the appropriate material for printing aorta to simulate contrast-enhanced CT imaging of type B aortic dissection. Due to lack of body phantom in the experiments, further research with simulation of realistic anatomical body environment should be conducted.


2018 ◽  
Vol 2018 (1) ◽  
pp. 000099-000103
Author(s):  
William A. Goodman

Abstract Goodman Technologies has been directly responsive to, and focused on, 3D printing and additive manufacturing techniques, and what it takes to manufacture in zero-gravity. During a NASA Phase I SBIR project, using a small multi-printhead machine, we showed that it was possible to formulate and 3D print silicon carbide into shapes appropriate for lightweight mirrors and structures at the production rate of 1.2 square-meter/day. Gradient lattice coupons with feature sizes on the order of 0.8mm were printed and were easily machined to very fine tolerances, ten-thousandths of an inch by Coastline Optics in Camarillo, CA. To further elaborate on the list of achievements, in Phase I, Team GT demonstrated three different ceramization techniques for 3D printing low areal cost, ultra-lightweight Silicon Carbide (SiC) mirrors and structures, radiation shielding, and electronics, several of which could be employed in microgravity The Goodman Technologies briefing presented at 2017 Mirror Technology Days “3D Printed Silicon Carbide Scalable to Meter-Class Segments for Far-Infrared Surveyor: NASA Contract NNX17CM29P along with sample coupons resulted in extreme interest from both Government and the Contractor communities. Our materials, which we call RoboSiC™, is suited for many other applications including heat sinks and radiation shielding for space electronics, and we have already started to make the first parts for these applications. The successful Phase I project suggests that we will meet or exceed all NASA requirements for the primary mirror of a Far-IR Surveyor such as the Origins Space Telescope (OST) and have a high probability solution for the LUVOIR Surveyor in time for the 2020 Decadal Survey. Results indicate that printing on the ground will achieve an areal density of 7.75 kg/square-meter (~39% of a James Webb Space Telescope (JWST) beryllium segment), a cost to print of $60K/segment, and an optical surface that has nanometer-scale tolerances. Printing in the microgravity environment of space we have the potential to achieve an areal density of 1.0–2.0 kg/square meter (&lt;10% of a JWST beryllium segment), with a cost to print of ~$10K/segment. The areal density is 2–15 times better than the NASA goal of 15 kg/square meter, and the costs are substantially better than the NASA goal of $100K/square meter. The encapsulated gradient lattice construction provides a uniform CTE throughout the part for dimensional stability, incredible specific stiffness, and the added benefit of cryo-damping. For the extreme wavefront control required by the Large UV/Optical/IR Surveyor (LUVOIR) the regularly spaced lattice construction should also provide deterministic mapping of any optical distortions directly to the regular actuator spacing of a deformable mirror (DM). Some of our processes will also allow for direct embedding of electronics for active structures and segments. Encapsulation of the lattice structures will allow for actively cooling with helium for unprecedented low emissivity and thermal control. Several decades of experience and testing with SiC have shown that our materials will survive, nay thrive in, the most extreme Space, Cryogenic, Laser and Nuclear Environments.


2020 ◽  
Vol 44 (2) ◽  
pp. 69-73
Author(s):  
Paul D. Bishop ◽  
Thomas Fultz ◽  
Lisa Smith ◽  
Ryan S. Klatte ◽  
Francis Loth ◽  
...  

Three-dimensional (3D) printing of anatomical structures has yielded valuable models for simulation, education, and surgical planning applications. Applications for 3D printing have continued to expand to include some ultrasound applications. The goal of this effort was to evaluate if a 3D printed model of a superficial femoral artery (SFA) would have realistic ultrasound characteristics. A computed tomography scan was 3D reconstructed and segmented using TeraRecon Aquarius Intuition software (TeraRecon, Foster City, California) to obtain an atherosclerotic SFA geometry. Both the lumen geometry and calcified plaque geometry of the SFA were exported as a stereolithographic (STL) file. The STL file was printed with An Object350 Connex 3D System using 2 different materials selected based on published elastic modulus data. VeroWhite was selected for the calcified plaque and TangoPlus Clear was selected for the artery wall. After printing, the SFA model was imaged in a water bath with a Phillips IU22 duplex ultrasound console and L12-9 ultrasound probe. Ultrasound imaging of the SFA model yielded grayscale views of artery geometry. Lumen geometry of the SFA model was similar to the actual artery geometry. Ultrasound was able to discern between the 3D print materials and visualize regions with stenosis. Suboptimal ultrasound parameters of echogenicity and wave velocity noted to differ from biological tissue. Total 3D print material cost was estimated at below $20. Although the 3D printed model did not have fully accurate ultrasound characteristics, it still provided realistic imaging. With further research, 3D printed models may offer a low-cost alternative for ultrasound phantoms.


2020 ◽  
Vol 26 (7) ◽  
pp. 1217-1225
Author(s):  
Ranjeet Agarwala ◽  
Carlos J. Anciano ◽  
Joshua Stevens ◽  
Robert Allen Chin ◽  
Preston Sparks

Purpose The purpose of the paper was to present a specific case study of how 3D printing was introduced in the chest wall construction process of a specific patient with unique medical condition. A life-size 3D model of the patient’s chest wall was 3D printed for pre-surgical planning. The intent was to eliminate the need for operative exposure to map the pathological area. The model was used for preoperative visualization and formation of a 1-mm thick titanium plate implant, which was placed in the patient during chest wall reconstructive surgery. The purpose of the surgery was to relive debilitating chronic pain due to right scapular entrapment. Design/methodology/approach The patient was born with a twisted spine. Over time, it progressed to severe and debilitating scoliosis, which required the use of a thoracic brace. Computerized tomography (CT) data were converted to a 3D printed model. The model was used to size and form a 1-mm thick titanium plate implant. It was also used to determine the ideal location for placement of the plate during thoracotomy preoperatively. Findings The surgery, aided by the model, was successful and resulted in a significantly smaller incision. The techniques reduced invasiveness and enabled the doctors to conduct the procedure efficiently and decreased surgery time. The patient experienced relief of the chronic debilitating pain and no longer need the thoracic brace. Originality/value The 3D model facilitated pre-operative planning and modeling of the implant. It also enabled accurate incision locations of the thoracotomy site and placement of the implant. Although chest wall reconstruction surgeries have been undertaken, this paper documents a specific case study of chest wall construction fora specific patient with unique pathological conditions.


Biomolecules ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1577
Author(s):  
Zhonghua Sun

Three-dimensional (3D) printing has been increasingly used in medicine with applications in many different fields ranging from orthopaedics and tumours to cardiovascular disease. Realistic 3D models can be printed with different materials to replicate anatomical structures and pathologies with high accuracy. 3D printed models generated from medical imaging data acquired with computed tomography, magnetic resonance imaging or ultrasound augment the understanding of complex anatomy and pathology, assist preoperative planning and simulate surgical or interventional procedures to achieve precision medicine for improvement of treatment outcomes, train young or junior doctors to gain their confidence in patient management and provide medical education to medical students or healthcare professionals as an effective training tool. This article provides an overview of patient-specific 3D printed models with a focus on the applications in cardiovascular disease including: 3D printed models in congenital heart disease, coronary artery disease, pulmonary embolism, aortic aneurysm and aortic dissection, and aortic valvular disease. Clinical value of the patient-specific 3D printed models in these areas is presented based on the current literature, while limitations and future research in 3D printing including bioprinting of cardiovascular disease are highlighted.


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