A System for Quantifying the Informativeness and Efficiency of the Connected Speech of Adults With Aphasia

1993 ◽  
Vol 36 (2) ◽  
pp. 338-350 ◽  
Author(s):  
Linda E. Nicholas ◽  
Robert H. Brookshire
Keyword(s):  
Scoring System ◽  
Connected Speech ◽  
Rule Based ◽  
Individual Basis ◽  
Information Unit ◽  
Correct Information ◽  
Significant Difference ◽  
Interjudge Reliability

A standardized rule-based scoring system, the Correct Information Unit (CIU) analysis, was used to evaluate the informativeness and efficiency of the connected speech of 20 non-brain-damaged adults and 20 adults with aphasia in response to 10 elicitation stimuli. The interjudge reliability of the scoring system proved to be high, as did the session-to-session stability of performance on measures. There was a significant difference between the non-brain-damaged and aphasic speakers on each of the five measures derived from CIU and word counts. However, the three calculated measures (words per minute, percent CIUs, and CIUs per minute) more dependably separated aphasic from non-brain-damaged speakers on an individual basis than the two counts (number of words and number of CIUs).

Concept Verification of a Remote Automatic Scoring System for Evaluating Knee Function after Total Knee Arthroplasty

2020 ◽  
Author(s):  
Haohua Zhang ◽  
Yixin Zhou
Keyword(s):  
Total Knee Arthroplasty ◽  
Data Acquisition ◽  
Knee Arthroplasty ◽  
Scoring System ◽  
Knee Function ◽  
Motion Sensor ◽  
Significant Difference ◽  
Cloud Server ◽  
Total Knee ◽  
Automatic Scoring

AbstractThe Knee Society Score (KSS) is the most commonly used scale for evaluating postoperative pain and physical function after total knee arthroplasty (TKA). However, this scale requires clinic visiting, which is not quite convenient. Our concept verification study demonstrated a remote automatic system for evaluating knee function after TKA using the KSS. The remote scoring system consists of two modules for data acquisition, an application for patients, a cloud server, and an application for doctors. The kinematic data are collected by the data acquisition modules and transmitted to the patient application via Bluetooth. The data acquisition module contains a motion sensor, a microcontroller unit, a power supply, and a Bluetooth module. The motion sensor consists of an accelerometer, a gyroscope, and a geomagnetic sensor, all of which are three-axis instruments. Using the nine-axis data, the three-dimensional (3D) angles are calculated according to the theory of attitude and heading reference system. The KSS score is calculated using a scoring algorithm in the patient application and transmitted to the doctor application through the cloud server. The knee function of 10 patients treated with unilateral TKA was evaluated by both a doctor and the remote scoring system. The consistency in KSS between the doctor and the system was analyzed using the paired t-test. The remote scoring system successfully recorded knee function data and transmitted the scores from the patient application to the doctor application through the cloud server. There was no significant difference in the KSS scores evaluated by the doctor and that by the system (p = 0.326). This remote automatic scoring system provides a reliable and convenient method for evaluating knee function after TKA at home.

scholarly journals To Compare the Functional Outcome of Intra Articular Distal end of Radius Fracture Treated by Conventional pop cast and External Fixatator Fixatation

2019 ◽  
Vol 4 (1) ◽  
pp. 586-591
Author(s):  
Pradeep Kumar Gupta ◽  
Ajay Kumar Yadav
Keyword(s):  
Functional Outcome ◽  
External Fixation ◽  
Closed Reduction ◽  
Scoring System ◽  
Radius Fracture ◽  
Definitive Treatment ◽  
Point System ◽  
Fixation Group ◽  
Significant Difference ◽  
Cast Group

Introduction: Distal end of radius fractures frequently have a high degree of comminution, instability, and associated with soft tissue injuries. Treatment of this distal radius fracture is controversial and there is no single definitive treatment method that is considered the standard of care. Objective: 1. To compare the functional results of the conventional POP cast and external fixator fixation of intra articular distal end of radius fracture. 2. To compare the radiological changes with that of functional outcome. Methodology: It was a prospective study comparing the functional outcome of distal intra-articular radius fracture when managed by conventional POP cast and external fixatator fixation. The final outcome was decided on the basis of modified Gartland and Werley scoring system. Total 50 patients (19 – 54 years) were recruited. 30 were treated by closed reduction and POP cast and 20 by external fixation. Radiological parameters were graded according to Schecks criteria and fracture comminution was classified according to Frykman's classification. Results: The functional outcome of the treatment was a subjective evaluation in which 80% of the patients had pain in external fixation as compared to 63% in closed reduction POP cast group. The restriction of activities was in 10% of the patient in external fixation group as compared with 33% in closed reduction POP cast group. The final scoring system as modification of Gartland and Werley point system had 5 ± 3 conventional pop cast group and 4 ± 4 in external fixation group. (p = 0.3764). On radiological evaluation, there was no significant difference in radial length, radial angle and volar tilt in two groups. Conclsion: The results show no statistically significant difference between the two modes of interventions. External fixation provides easy mobilization of fingers and reduces edema and stiffness of joints. The active ranges of movements at the wrist joints were significantly better in external fixation group. 

Body composition by air-displacement plethysmography by using predicted and measured thoracic gas volumes

1998 ◽  
Vol 84 (4) ◽  
pp. 1475-1479 ◽  
Author(s):  
Megan A. McCrory ◽  
Paul A. Molé ◽  
Terri D. Gomez ◽  
Kathryn G. Dewey ◽  
Edmund M. Bernauer
Keyword(s):  
Body Composition ◽  
Body Volume ◽  
Air Displacement Plethysmography ◽  
Bod Pod ◽  
Individual Basis ◽  
Thoracic Gas Volume ◽  
Significant Difference ◽  
Hydrostatic Weighing ◽  
Gas Volume ◽  
Boyle’S Law

The BOD POD, a new air-displacement plethysmograph for measuring human body composition, utilizes the inverse relationship between pressure and volume (Boyle’s law) to measure body volume directly. The quantity of air in the lungs during tidal breathing, the average thoracic gas volume (Vtg), is also measured by the BOD POD by using a standard plethysmographic technique. Alternatively, the BOD POD provides the use of a predicted Vtg (Vtgpred). The validity of using Vtgpred in place of measured Vtg (Vtgmeas) to determine the percentage of body fat (%BF) was evaluated in 50 subjects (36 women, 14 men; ages 18–56 yr). There was no significant difference between Vtgmeas and Vtgpred (mean difference ± SE, 53.5 ± 63.3 ml) nor in %BF by using Vtgmeas vs. Vtgpred (0.2 ± 0.2 %BF). On an individual basis, %BF measured by using Vtgmeas vs. Vtgpred differed within ±2.0% BF for 82% of the subjects; maximum differences were −2.9 to +3.0% BF. For comparison, data from 24 subjects who had undergone hydrostatic weighing were evaluated for the validity of using predicted vs. measured residual lung volume (Vr pred vs. Vr meas, respectively). Differences between Vr meas and Vr pred and in %BF calculated by using Vr meas vs. Vr pred were significant (187 ± 46 ml and 1.4 ± 0.3% BF, respectively; P < 0.001). On an individual basis, %BF determined by using Vr meas vs. Vr preddiffered within ±2.0% BF for 46% of the subjects; maximum differences were −2.9 to +3.8% BF. With respect to %BF measured by air displacement, our findings support the use of Vtgpred for group mean comparisons and for purposes such as screening in young to middle-aged individuals. This contrasts with the use of Vr pred in hydrostatic weighing, which leads to significant errors in the estimation of %BF. Furthermore, although the use of Vtgpred has some application, determining Vtgmeas is relatively simple in most cases. Therefore, we recommend that the use of Vtgmeas remain as standard experimental and clinical practice.

scholarly journals Cross-Cultural Adaptation and Quantitative Evaluation of Dysfunctional Voiding and Incontinence Scoring System in Pediatric Serbian Population

Medicina ◽  
2019 ◽  
Vol 55 (4) ◽  
pp. 100
Author(s):  
Dragana Cirovic ◽  
Ivana Petronic ◽  
Jasna Stojkovic ◽  
Ivan Soldatovic ◽  
Polina Pavicevic ◽  
...  
Keyword(s):  
Scoring System ◽  
Pediatric Population ◽  
Scoring Systems ◽  
Cross Sectional Study ◽  
Repeated Measurements ◽  
Receiver Operating Curve ◽  
Dysfunctional Voiding ◽  
Cross Sectional ◽  
Significant Difference ◽  
Test Retest Reliability

Background and objective: Dysfunctional voiding (DV) presents relatively frequent problem in pediatric urologist practice. The necessity for implementation of DV evaluation in the pediatric population is of particular importance, since there is no clear consensus on the clinical assessment of such condition. The aims of our study were to evaluate the test/retest reliability and reproducibility of dysfunctional voiding and incontinence scoring system: Serbian version (DVISSSR) in patients with voiding and incontinence dysfunctions without structural deformities, and to estimate cut-off value for DVISSSR. Methods: The cross-sectional study included 57 children with voiding and incontinence dysfunctions and 30 healthy pediatric controls. For the evaluation of voiding and incontinence dysfunction we used DVISS. The forward–backward method was applied for translation of the DVISS questionnaire from English into Serbian language. Reproducibility was analyzed by Interclass Correlation Coefficient (ICC). Sensitivity and specificity of DVISSSR scores was done by receiver operating curve (ROC) curve. Results: There was a significant difference in DVISSSR score between patients and controls (p < 0.001). For reliability and reproducibility of the questionnaire, there was no significant difference between repeated measurements (p = 0.141), and strong reliability (ICC = 0.957; p < 0.001). Conclusion: We have demonstrated successful translation and validation of the DVISSSR score. Moreover, a reliable scoring system of children with voiding dysfunctions should include evaluations of symptom scoring systems at the multicentric level.

scholarly journals Reconstruction of anterior cruciate ligament by using two different techniques

2010 ◽  
Vol 63 (11-12) ◽  
pp. 845-850 ◽  
Author(s):  
Vladimir Ristic ◽  
Srdjan Ninkovic ◽  
Vladimir Harhaji ◽  
Milan Stankovic ◽  
Dragan Savic ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Bone Graft ◽  
Scoring System ◽  
Cruciate Ligament ◽  
Group Versus ◽  
International Knee Documentation Committee ◽  
Rigid Fixation ◽  
Postoperative Results ◽  
Significant Difference ◽  
Anterior Cruciate

Introduction. Modern literature concerning reconstructions of Anterior Cruciate Ligament is mostly focused on the choice of graft (hamstring or bone-tendon-bone), its placing, tensioning and fixation. The bone-hamstring-bone graft consists of compressed cancellous bone on its ends and it has been developed to achieve a more rigid fixation of the graft. The aim of this study was to compare the postoperative results in surgically treated patients two years after the reconstruction of anterior cruciate ligament. Material and methods. The study included 55 patients divided into two groups according to the implanted graft: bone-tendon-bone and bone-hamstring-bone graft. The results were assessed by Tegner and Lysholm scoring systems, arthrometric measurements, functional tests and International Knee Documentation Committee standard. Results. The average postoperative results did not show a statistically significant difference (p<0.05) between the two groups (94 in the bone-tendon-bone group versus 93 in the bone-hamstring-bone group) according to Lysholm scoring system, nor in the arthrometric measurements obtained by Lachman test (2.0:2.1). According to the International Knee Documentation Committee standard, the bone-hamstring-bone group had more excellent results, but also three unsatisfactory ones; so, the bone-tendon-bone group was found to have uniform and better results (100% of excellent and good results vs. 91% in the bone-hamstring-bone group). Better results were also recorded by Tegner scoring system in the bone-tendon-bone group (8.6 vs. 7.1) due to the fact that there were more active athletes and greater preoperative level of activities in this group (3.1 vs.7.l in the bone-hamstring group). Conclusions. The choice of graft is a less important factor in the reconstruction of anterior cruciate ligament than its placing, tensioning and fixation, because a significant difference between groups was recorded only by the International Knee Documentation Committee standard.

The Clinical Features and Prognosis of Early T-Cell Precursor Subtype of Lymphoblastic Lymphoma in the Japanese Pediatric Leukemia/Lymphoma Study Group ALB-NHL03 Study

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 1728-1728
Author(s):  
Reiji Fukano ◽  
Shosuke Sunami ◽  
Masahiro Sekimizu ◽  
Tetsuya Takimoto ◽  
Tetsuya Mori ◽  
...  
Keyword(s):  
T Cell ◽  
Scoring System ◽  
Lymphoblastic Lymphoma ◽  
Study Group ◽  
Advanced Stage ◽  
Sufficient Data ◽  
Cell Precursor ◽  
Pediatric Leukemia ◽  
Significant Difference ◽  
Lymphoma Study Group

Abstract Introduction: Recently, early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) was identified as a subtype of T-cell ALL (T-ALL), with distinctive gene expression and cell marker profiles. Some reports revealed that ETP-ALL was associated with a high risk of remission induction failure and relapse. In precursor T-cell lymphoblastic lymphoma (T-LBL), the clinical features and prognosis of the ETP subtype are not clear yet. In this study, we analyzed the data obtained from patients of advanced stage T-LBL to clarify the prognosis of pediatric T-LBL according to the immunophenotypes, including the ETP subtype of LBL. Patients and methods: From November 2004 to October 2010, 136 children (aged 1–18 years) with newly diagnosed advanced stage LBL (stages III and IV) were eligible for the Japanese Pediatric Leukemia/Lymphoma Study Group ALB-NHL03 study. We analyzed their immunophenotyping data as well as the ETP subtype. The immunophenotype of T-LBL was classified into pro-T, pre-T, intermediate T, and mature T based on the European Group for the Immunological Characterization of Leukemias (EGIL) classification. The definition of ETP subtype LBL was based on a previous report from the Tokyo Children’s Cancer Study Group (Inukai et al, 2011) using a scoring system consisting of the following 11 markers: CD4, CD8, CD13, CD33, CD34, HLA-DR, CD2, CD3, CD4, CD10, and CD56. Both definitions were based on flow cytometric analysis. Results: In this analysis, 104 (76%) patients were diagnosed with T-LBL. Sufficient data to evaluate the EGIL classification was available for 40 out of 104 patients. The remaining patients could not be classified due to incomplete immunophenotypic data. There were 1, 9, 21, and 9 cases of Pro-T, pre-T, intermediate T, and mature T, respectively. The 3-year event-free survival (EFS) of pro-T/pre-T and intermediate T/mature T was 80.0 ± 12.7% and 76.7 ± 7.7%, respectively (P = 0.7586). For evaluating the ETP subtype of LBL, sufficient data, obtained by using the scoring system with 11 markers, was available for 40 patients. Eight (20%) and 32 (80%) patients were classified as having ETP and non-ETP subtype, respectively. Bone marrow involvement for patients with ETP and non-ETP subtype was observed in 7 (88%) and 11 (34%) cases, respectively (P = 0.014). Central nervous system involvement in patients with ETP and non-ETP subtype was observed in 2 (25%) and 0 cases, respectively (P = 0.036). Thus, stage IV classification was more frequently observed in patients with ETP subtype than in patients with non-ETP subtype (P = 0.014). The 3-year EFS of patients with ETP and non-ETP subtype were 75.0 ± 15.3% and 71.9 ± 8.0%, respectively. There was no significant difference in EFS between patients with ETP and non-ETP subtype (P = 0.8281). Conclusion: For 40 out of 104 T-LBL patients, sufficient data was available to evaluate the immunophenotype for EGIL classification and ETP subtype. There was no significant difference in EFS according to the immunophenotypic subtype of T-LBL. In contrast to T-ALL, ETP subtype in LBL was not statistically related to EFS in this analysis. Disclosures No relevant conflicts of interest to declare.

Chemotherapy and survival benefit in elderly patients with advanced gastric cancer.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 45-45 ◽  
Author(s):  
Aya Sugimoto ◽  
Tsutomu Nishida ◽  
Kei Takahashi ◽  
Kaori Mukai ◽  
Tokuhiro Matsubara ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Advanced Gastric Cancer ◽  
Scoring System ◽  
Survival Benefit ◽  
Poor Prognosis ◽  
Risk Group ◽  
Univariate Analysis ◽  
Significant Difference ◽  
Total Point

45 Background:There is little evidence if chemotherapy (CT) offer survival benefit for elderly patients (EP) with advanced gastric cancer (AGC). Methods: This was a single-centre retrospective study. A total of 118 patients with AGC were hospitalized at our hospital from April 2012 to June 2016. Of them, EP older than 75 years with AGC were eligible for inclusion in the study. Basically, the treatment strategy, chemotherapy (CT) or best supportive care (BSC) were comprehensively decided according to their background. We evaluate the risk factors for survival using the Cox proportional hazard model and explored the optimal indication for CT for EP. Results: Of 118 patients with AGC, 47 patients were enrolled as EP [63% men; mean age, 81 years]. Of EP, 26 patients (55%) received CT and 21 patients received BSC. As first-line CT, 13 patients received S1 monotherapy, the others treated with combination agents. The median overall survival time (MST) was 138 days. There was no significant difference between CT and BSC group (172 vs. 118 days, p = 0. 1087). Univariate analysis revealed the following 5 factors for poor prognosis were significant (defined as p-value < 0.1): Performance status (PS) 3a 2 (HR3.7, 95% CI: 1.5-8.5), C-reactive protein levels 3a 1mg/dL (HR4.0, 95% CI: 1.8-9.4), albumin level < 3g/dL (HR2.1, 95% CI: 1.1-4.3), neutrophil/lymphocyte ratio (NLR) 3a 4 (HR3.7, 95% CI: 1.7-8.5), and diffuse type (HR1.8, 95% CI: 0.9-3.8). As each poor risk factor of 5 and age factor 3a 80 years represents point 1, we calculated total points (0-6) for each patient. Median total points of CT and BSC were 2 and 4, respectively (p = 0.0196). Therefore, we set cut-off point of 3. Then, EP with a total point of 3 and more were classified as high risk group (HR: N = 25) and the others were as low risk group (LR: N = 22). There was significantly longer MST in LR than HR (all EP; 457 vs 105 days, HR: 0.23, p = 0.0002 and EP with CT; 232 vs 113 days, HR:0.26, p = 0.0085). Conclusions: Our findings using the scoring system including 6 factors suggest that EP with a total point 3 and more, were poor prognosis and may not receive benefit from CT for AGC. When judging indication for CT in EP with AGC, this scoring system may be useful, and in case of LR (total point 0-2) may be considered an indication for CT.

Discrepancy of blast percentage between the bone marrow aspirate and biopsy and its impact on survival outcomes in patients with myelodysplastic syndromes excess blast (MDS-EB).

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 7053-7053
Author(s):  
Meera Yogarajah ◽  
Phuong L. Nguyen ◽  
Rong He ◽  
Hassan Alkhateeb ◽  
Mithun Vinod Shah ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Scoring System ◽  
Small Sample Size ◽  
Scoring Systems ◽  
Standard Of Care ◽  
Small Sample ◽  
International Prognostic Scoring System ◽  
Increased Risk ◽  
Significant Difference ◽  
Impact On Survival

7053 Background: The revised International Prognostic Scoring System (IPSS-R) aids in prognosticating MDS. The percentage (%) of blasts in the bone marrow is one of the major determinants of the scoring system. The aspirate blast % is utilized as the standard of care, but there could be discrepancies in the blast % reported by the aspirate and the biopsy. We aim to study the possible use of bone marrow biopsy blasts in MDS-EB in calculating IPSS-R. Methods: The MDS database was reviewed for cases of MDS-EB after due IRB approval. We calculated IPSS-R scores based on the aspirate blast % (IPSS-RAsp) and biopsy blast % (IPSS-RBx). The biopsy blast % was reported morphologically or by the CD34 stain. Whenever a range was reported the highest value was utilized as the blast %. Suboptimal aspirates were excluded from the study. The overall survival (OS) was determined by IPSS-RAsp, IPSS-RBx and IPSS-R highest blast (IPSS-RHi). OS estimates were calculated by Kaplan-Meier curves and log-rank testing using JMP v.13. Uno’s concordance statistic was used to compare all 3 risk scoring systems. Results: Of 1322 patients, 431 (33%) cases were identified with MDS-EB; out of which 173 cases had both blasts reported in the biopsy and the aspirate. Out of 173 cases, 35 (20%) had MDS-EB1, and 61 (35%) had MDS EB-2 based on both biopsy and aspirate (concordant cases). Seventy seven (45%) patients changed from EB-1 to EB2 or vice versa based on the biopsy blast (44/77 (57%) cases were upstaged). The OS outcomes based on the IPSS-RBx biopsy showed a clear and meaningful separation with median OS decreasing with increased risk but IPSS-RAsp and IPSS-RHi did not (Table). We compared the 3 models for observed OS differences using the Uno model and there was no statistically significant difference. Conclusions: IPSS-RBx (but not IPSS-RAsp and IPSS-RHi) identified prognostic groups for OS with median OS decreasing with increased risk. The small sample size may have led to an insignificant effect on model power by Uno model. This finding needs to be validated by other centers. [Table: see text]

Sign in / Sign up

Export Citation Format

Share Document