scholarly journals Descriptive characteristics of the cohort of workers from the Siberian Group of Chemical Enterprises (SGCE)

2019 ◽  
Vol 14 ◽  
pp. 04012
Author(s):  
Andrey Karpov ◽  
Ravil Takhauov ◽  
Andrey Zerenkov ◽  
Yuriy Dolgopolov ◽  
Konstantin Izmestev ◽  
...  
Keyword(s):  
1983 ◽  
Vol 4 (2) ◽  
pp. 265-271 ◽  
Author(s):  
Wolfgang Böhme ◽  
Ulrich Joger

AbstractVipera baranin. sp. from northwestern Turkey is a member of the euro-siberian group within the genus Vipera. It is characterized by the following peculiarities: 1) Higher ventral count than V. ursinii and V. kaznakovi (145). 2) ♀ with a higher subcaudal count than V. ursinii, V. kaznakovi and V. berus (37). 3) Loreal scales and head plates divided to an extent as in the western European V. aspis (5 "loreals", 34 "intercanthals and intersupraoculars", parietals fully divided into small scales). 4) Different from V. aspis in having only one row of subocular scales between eye and supralabials. 5) The three specimens known up to now are totally melanistic, with white supralabials and a bright yellow underside of tail. The possibility ofy hybrid nature of the only preserved specimen is discussed and dimissed. As long as no further material is known, the relationships of V. barani to the other species can not be clarified.


2021 ◽  
Vol 66 (1) ◽  
pp. 37-43
Author(s):  
Yu. Semenova ◽  
A. Karpov ◽  
T. Takhauova ◽  
D. Kalinkin ◽  
A. Takhauov ◽  
...  

Purpose: To examine the predictors of acute myocardial infarction development and to evaluate the relationship of the radiation component (external γ-radiation) with the probability of developing acute myocardial infarction in workers of radiation-dangerous plants working age (under 60 for men, 55 for women), by the example of the Siberian Group of Chemical Enterprises personnel. Material and methods: The work is based on the results of a prospective population study (1998–2013). The diagnosis of acute myocardial infarction was verified in 540 people of working age (34 women and 506 men). For each case selected control (n = 1,080) among the employees of the Siberian Group of Chemical Enterprises, passed periodic medical examination in the study period. Every person was described by means of 46 variables including characteristics of social status, a number of risk factors, associated diseases, biochemical indices including the level of general cholesterol, the main clinical data, cumulative dose of external radiation and the amount of 239Pu content in an organism. Results: It was determined that in the group of the personnel of working age the most important traditional predictors of acute myocardial infarction, less important factor in the pathogenesis of the disease are conditions of the individual accumulation of a dose, but not the magnitude of the total external doses in the evaluation range. Conclusion: To improve the system of preventive measures aimed at reducing the level of morbidity and mortality from acute myocardial infarction, it is recommended to form risk groups taking into account the most significant predictors of this disease (age, systolic blood pressure, smoking). For the personnel of radiation dangerous plants working age insignificant conditions for the formation of radiation dose (age of first exposure, the rate of accumulation of radiation dose, duration of exposure) under conditions of trouble-free operation of the equipment. Active measures for the diagnosis of coronary heart disease and targeted correction of detected somatic disorders for the prevention of acute vascular catastrophes are expedient for workers of radiation hazardous industries from 40 to 60 years with an individual risk of acute myocardial infarction less than 50 % using the model described below.


2021 ◽  
Vol 20 (5) ◽  
pp. 5-17
Author(s):  
D. E. Kalinkin ◽  
R. M. Takhauov ◽  
I. V. Milto ◽  
A. B. Karpov ◽  
L. R. Takhauova ◽  
...  

Background. One of the main directions in the field of ensuring radiation safety of “nuclear legacy” facilities is the assessment of radiation effects and most significant radiogenic risks in employees of nuclear enterprises and their descendants.Objective. Analysis of the cancer incidence among employees of the Siberian Group of Chemical Enterprises (SGCE) exposed to ionizing radiation in the course of their professional activities.Material and Methods. The actual values and standardized estimated risks of developing cancer among the SGCE workers occupationally exposed to ionizing radiation were calculated using generally accepted methods based on the information of the regional medical dosimetry registry of Seversk Biophysical Research Center of FMBA, containing updated data on all SGCE employees diagnosed with cancer (period from 01.01.1950 to 31.12.2015 inclusive). The control group consisted of workers who were not occupationally exposed to ionizing radiation.Results. Among the male personnel of the SGCE, the highest incidence of cancer of the digestive, respiratory, and skin organs (including melanoma) was observed in patients aged 50–59 and 70–79 years. Among the female workers, the highest cancer incidence was in the age group 40–49 years; cancer of the gastrointestinal tract, genital tract and breast was the most common. The cancer incidence rate in the SGCE workers who occupationally exposed to ionizing radiation was not higher that that observed in the control group. The median age of male cancer patients occupationally exposed to ionizing radiation was significantly lower than the median age of male cancer patients of the control group. In female cancer patients, a significant difference in the median age of cancer diagnosis was found only in relation to skin cancer. Both male and female SGCE personnel occupationally exposed to ionizing radiation was at high risk of certain cancers: among male patients – cancer of the mesothelium and soft tissues, genital organs, eyes and brain, as well as multiple primary tumors; among female patients – cancer of lips, oral cavity, pharynx, digestive system, respiratory system, skin (including melanoma), mesothelium, soft tissues, breast, urinary tract, lymphatic and hematopoietic tissues, as well as multiple primary tumors.Conclusion. The data obtained will allow determination of the main directions for assessing the health risks of personnel of radiation hazardous facilities and the formation of a set of measures aimed at improving the system of protection and improving the health of workers at radiation hazardous enterprises and the extension of their working longevity. 


Author(s):  
Anatoly Bushuev ◽  
Yury Verzilov ◽  
Victor Zubarev ◽  
Tatiana Aleeva ◽  
Ekaterina Petrova ◽  
...  

Abstract The paper is devoted to investigations of spent reactor graphite contamination. The study was based on the sampling from the graphite stacks and sleeves of three shut down plutonium-production reactors in Siberian Group of Chemical Enterprises (SGCE), Seversk (Tomsk-7). Several hundreds graphite samples were analysed by means of α-, β-, γ- and X-ray spectrometry. Contents of 3H, 14C, fission products, actinides, products of impurities neutron activation were determined. The inventories of above mentioned radionuclides were estimated. Correlation between content of various groups of radionuclides was studied. Graphite sleeves contamination was studied depending on the period of their irradiation. Comparison of obtained experimental data for the three SGCE reactors with calculated predictions showed substantial difference. The conclusion was made on applicability of the data obtained for estimations of spent graphite contamination in other reactor types including RBMK reactors. The main part of the studies was performed in the frame of the ISTC Projects No. 561 and No. 1409 fulfilment.


2020 ◽  
Vol 65 (4) ◽  
pp. 5-11
Author(s):  
D. Kalinkin ◽  
T. Takhauova ◽  
A. Karpov ◽  
Yu. Samoilova ◽  
M. Plaksin ◽  
...  

Purpose: Development of the basic directions of a modern strategy for protecting the health of the adult population living in the activity zone of nuclear industry enterprises (using the example of the Seversk population). Material and methods: The object of the study was the population of the city of Seversk, formed around the Siberian Group of Chemical Enterprises. The subject of the study was demographic indicators; disability; incidence of malignant neoplasms, diseases of the circulatory system, injuries and accidents); socio-economic, behavioral and technological risk factors affecting the occurrence of major diseases. Results: It was established that by the end of the study period (1970–2017), the studied population was in a state of natural population decline due to a decrease in the birth rate and an increase in mortality, while the mortality rate exceeded the birth rate. During the period under review, the primary incidence of malignant neoplasia significantly increased; at the same time, the incidence of cardiovascular diseases, as well as the frequency of injuries and poisoning, decreased. Among the adult population of Seversk, behavioral factors (the habit of smoking, regular use of alcohol, a sedentary lifestyle, lack of regular physical activity) are more common than socio-economic (living conditions, financial situation) risk factors. Important risk factors are incorrect assessment by citizens of their own health and the reasons for its violation. Among Siberian Group of Chemical Enterprises workers exposed to tekhnogenic risk factor (long-term occupational exposure), there is an increased risk of cancer death of all localizations taken together, respiratory and digestive organs; bones, joints, mesothelium, soft tissues and genitals. At the same time, the risk of oncological mortality during irradiation was not exceeded in the range of small doses of (up to 100 mSv), and for any of the localization of malignant neoplasms this effect is not dose-dependent. Conclusion: The data obtained made it possible to specify and substantiate the basic directions of the modern strategy for protecting the health of the adult population living in the activity zone of nuclear industry enterprises (using the example of the Seversk population).


2002 ◽  
Vol 140 (1) ◽  
pp. 51-62 ◽  
Author(s):  
Anatoly Y. Bushuev ◽  
Yury M. Verzilov ◽  
Viktor N. Zubarev ◽  
Alexander E. Kachanovsky ◽  
Igor M. Proshin ◽  
...  

2009 ◽  
Vol 7 (4) ◽  
pp. 23-33 ◽  
Author(s):  
Nikolay V Litvjakov ◽  
Maksim B Freydin ◽  
Ravil M Takhauov ◽  
Alena M Ageeva ◽  
Natalia M Volkova ◽  
...  

The association of 13 biallelic polymorphisms of genes hOGG1 977C > G, XPD1 2251A > C, XPG1 3310G > C, XRCC1:580C> T, 839G >A, 1196G>A GSTT1 («+»/«-»), GSTM1 («+»/«-»), CYP2C19 681G> A, NOS3: -665C>T, 774С> T, 894G > T, VNTRint4 with risk of development of malignant new growths (MNG) in conditions of "low-dose" ionizing irradiation was investigated. In 1 group of irradiated patients of malignant new growths there are 96 persons, in 2 group of non-irradiated patients of MNG - 135 persons, in 3 control group - 148 healthy irradiated workers of the Siberian Group of Chemical Enterprises. By means of procedure FDR it is shown that only polymorphic variants of gene CYP2C19681G* are authentically associated with risk of occurrence of MNG against an irradiation. 1 genotype consisting of a combination of 5 polymorphic loci is selected. Frequency of occurrence of this genotype in 1 group makes 16,9 % (14/83), in 2 group - 1,0 % (1/100), in 3 group - 0,84 % (1/119). At its carriers in conditions of low-dose irradiation more than in 20 times the risk of occurrence of MNG (OR between 1 and 3 groups (95 % CI) = 24,14 (3,21-502,64) increases; p = 0,0000581, taking into account the correction of Bonferroni р = 0,01046).


2020 ◽  
Vol 13 (4) ◽  
pp. 615-622
Author(s):  
Irina Vyacheslavovna Pchelovodova ◽  
Ekaterina Anatoljevna Sofronova ◽  
Denis Leonidovich Kornilov

The article considers archival sound collections according to the musical and song tradition of the Siberian group of Udmurts living in the Krasnoyarsk region and the Tomsk region. The main stock repository today is the phonogrammarchiv of the Udmurt Institute of History, Language and Literature of the UdmFRC UB RAS. Expeditionary recordings made in 1974 and 2006 make it possible to trace the state of musical folklore in dynamics. Analysis of the field material showed a decrease in the number of songs and the complete disappearance of rites in late recordings, while the layer of non-ritual songs survived quite well. The same phenomenon (partial disappearance of the rite layer of songs and the prevalence of the non-ritual) we see in the Udmurt traditional culture. In our opinion, this is facilitated by the emotional component of non-ritual songs, which is relevant at all times. During the course of the work, new materials stored in other funds were identified and will be considered in subsequent studies. The further planned comparative analysis of musical folklore of the Udmurt resettlement tradition with autochthonous tradition will allow relating the degree of preservation and/or loss of its components.


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