scholarly journals The inhibitory effect of Eupatorium adenophorum extracts on the pathogen of postharvest disease of banana

2020 ◽  
Vol 185 ◽  
pp. 03038
Author(s):  
Weifeng Zhao ◽  
Weixiu Yang ◽  
Ying Li ◽  
Junying Cao ◽  
Xiaohuan Yang ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Antibacterial Effect ◽  
Inhibitory Effect ◽  
Postharvest Disease ◽  
Eupatorium Adenophorum ◽  
Post Harvest ◽  
Fusarium Semitectum ◽  
Colletotrichum Musae ◽  
Better Than ◽  
Three Components

The Colletotrichum musae and Fusarium semitectum Berk., Which often occur in banana after harvest were used as the targets. Three components with antibacterial activity extracted from the leaves of the plant were used as "fungicide". The antibacterial effect of the three component substances on the pathogens of anthracnose and shaft rot was studied. The results showed that the inhibitory rates of the components A, B and C at 2 mg / ml on the pathogens of banana anthracnose and shaft rot reached 82.53%, 79.91%, 78.30% and 82.2%, 78.69% and 81.17% respectively. The EC90 values of component A, B and C for banana anthracnose pathogens were 1.70, 1.85, and 1.69 mg / ml. Respectively, the EC90 values for banana shaft rot pathogens were 1.37, 1.38, and 1.64 mg / ml. The antibacterial effect of the three component substances on the pathogen of banana shaft rot was better than that of anthracnose. The three component substances have great potential for controlling post-harvest anthracnose and shaft rot of bananas.

scholarly journals Design, Synthesis and Antibacterial Activity of Novel Pyrimidine-Containing 4H-Chromen-4-one Derivatives

2020 ◽  
Author(s):  
Shijun Su ◽  
Mei Chen ◽  
Xuemei Tang ◽  
Feng Peng ◽  
Tingting Liu ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Inhibitory Effect ◽  
Xanthomonas Oryzae ◽  
Design Synthesis ◽  
H Nmr ◽  
Half Maximal Effective Concentration ◽  
Bacterial Cell Membrane ◽  
Better Than ◽  
C Nmr

Abstract A series of pyrimidine-containing 4H-chromen-4-one derivatives were designed and synthesized by combining bioactive substructures. All compounds were characterized using 1H NMR, 13C NMR, 19F NMR and HRMS. Preliminary biological activity results showed that most of title compounds displayed significant inhibitory activity against Xanthomonas axonopodis pv. Citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Ralstonia solanacearum (Rs). In particular, compound 4c demonstrated a good inhibitory effect against Xac and Xoo, with half-maximal effective concentration(EC50) values of 15.5 and 14.9 μg/mL respectively, and that of compound 4h showed the best antibacterial activity against Rs with an EC50 value of 14.7 μg/mL, These results were better than both bismerthiazol (BT, 51.7, 70.1 and 52.7 μg/mL, respectively) and thiodiazole copper (TC, 77.9, 95.8 and 72.1 μg/mL respectively). In vivo antibacterial activity results indicated that compound 4c displayed better curative(42.4%) and protective (49.2%) activities for reducing rice bacterial leaf blight than both BT (35.2, 39.1%) and TC (30.8, 27.3%). The mechanism of compound 4c against Xoo was analysed through scanning electron microscopy (SEM). Results showed that the compound destroied the bacterial cell membrane structure. These results indicated that pyrimidine-containing 4H-chromen-4-one derivatives are valuable in the research of new agrochemicals.

Research on Properties of Antibacterial Paper Sprayed by Nano-Chitosan

2014 ◽  
Vol 926-930 ◽  
pp. 214-217
Author(s):  
Ying Hong ◽  
Li Ze Tang
Keyword(s):  
Staphylococcus Aureus ◽  
Tensile Strength ◽  
Antibacterial Effect ◽  
Circle Method ◽  
Inhibitory Effect ◽  
Bursting Strength ◽  
Obvious Change ◽  
And Staphylococcus Aureus ◽  
Better Than

Antibacterial paper for packaging was sprayed by nanochitosan as antibacterial ingredients. The bacteriostatic circle method was adopted to evaluate its antibacterial effect on E.coli and Staphylococcus aureus. We investigated the effects of different concentrations of nanochitosan on antibacterial paper thickness, tensile strength, bursting strength, folding strength and antibacterial properties.The results showed that: tensile strength, bursting strength and folding strength of the antibacterial paper is better than the control paper and the thickness has no obvious change. The antibacterial paper enhanced the antibacterial effect following the increasing concentration of nanochitosan. The same concentration of nanochitosan antibacterial paper, its inhibitory effect on E.coli was greater than that of Staphylococcus aureus.

scholarly journals Green synthesis, characterization and antibacterial activities of silver nanoparticles from strawberry fruit extract

2017 ◽  
Vol 19 (4) ◽  
pp. 128-136 ◽  
Author(s):  
Saviour A. Umoren ◽  
Alexis M. Nzila ◽  
Saravanan Sankaran ◽  
Moses M. Solomon ◽  
Peace S. Umoren
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Room Temperature ◽  
Size Range ◽  
Antibacterial Activities ◽  
Inhibitory Effect ◽  
Strawberry Fruit ◽  
Fruit Extract ◽  
Vis Spectroscopy ◽  
Better Than

Abstract Silver nanoparticles (AgNPs) have been synthesized in the presence of Strawberry fruit extract (SBFE) at room temperature. The synthesized AgNPs was characterized by UV-vis spectroscopy, SEM, EDS, XRD, TEM and FTIR. The UV-vis spectra of the AgNPs show SPR band at 450 nm. TEM results indicate that AgNPs are spherical in shape and size range between 7–65 nm. Antibacterial activity of the synthesized AgNPs has been assessed against Pseudomonas aeruginosa and Bacillus licheniformis. The results show that AgNPs exhibit inhibitory effect and effect is a function of AgNPs concentration. The antibacterial activity of the prepared AgNPs has been compared with two antibiotics, amoxicillin and ciprofloxacin. It is found that the antibiotics perform better than AgNPs.

Study on Antisepsis and Preservation of Dapingding Jujube

2014 ◽  
Vol 971-973 ◽  
pp. 174-177
Author(s):  
Zhan Ru Ma ◽  
Lan Chen ◽  
Xiao Bo Zhang ◽  
Xi Hong Li ◽  
Jin Shan Luo ◽  
...  
Keyword(s):  
Antibacterial Effect ◽  
Inhibitory Effect ◽  
Fruit Firmness ◽  
Microbial Infection ◽  
Postharvest Diseases ◽  
Cinnamon Oil ◽  
Rot Disease ◽  
Effect Of The Composition ◽  
Better Than

This paper investigated the microbial infection of postharvest diseases of Dapingding jujube and cited the symptoms of common rot disease .At the same time, the antibacterial effect of cinnamon oil, natamycin and their composition on Dapingding jujube during the period of storage were studied. The results showed that the preservation inhibitory effect of cinnamon oil was better than natamycin at earlier storage, but just the opposite at later storage, while, the effect of the composition had been very good during the whole storage with higher rate of intact fruit, better fruit firmness and lower cankered index.

scholarly journals Synthesis and Antibacterial Evaluation of Novel 1,3,4-Oxadiazole Derivatives Containing Sulfonate/Carboxylate Moiety

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1488
Author(s):  
Lei Wang ◽  
Xia Zhou ◽  
Hui Lu ◽  
Xianfu Mu ◽  
Linhong Jin
Keyword(s):  
Antibacterial Activity ◽  
Inhibitory Effect ◽  
Sem Analysis ◽  
Leaf Blight ◽  
Xanthomonas Oryzae ◽  
Bacterial Leaf Blight ◽  
Xanthomonas Axonopodis ◽  
Better Than

In order to discover new lead compounds with high antibacterial activity, a series of new derivatives were designed and synthesized by introducing a sulfonate or carboxylate moiety into the 1,3,4-oxadiazole structure. Antibacterial activity against two phytopathogens, Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac), was assayed in vitro. The preliminary results indicated that ten compounds including 4a-1-4a-4 and 4a-11-4a-16 had good antibacterial activity against Xoo, with EC50 values ranging from 50.1-112.5 µM, which was better than those of Bismerthiazol (253.5 µM) and Thiodiazole copper (467.4 µM). Meanwhile, 4a-1, 4a-2, 4a-3 and 4a-4 demonstrated good inhibitory effect against Xanthomonas axonopodis pv. citri with EC50 values around 95.8-155.2 µM which were better than those of bismerthiazol (274.3 µM) and thiodiazole copper (406.3 µM). In addition, in vivo protection activity of compound 4a-2 and 4a-3 against rice bacterial leaf blight was 68.6% and 62.3%, respectively, which were better than bismerthiazol (49.6%) and thiodiazole copper (42.2%). Curative activity of compound 4a-2 and 4a-3 against rice bacterial leaf blight was 62.3% and 56.0%, which were better than bismerthiazol (42.9%) and thiodiazole copper (36.1%). Through scanning electron microscopy (SEM) analysis, it was observed that compound 4a-2 caused the cell membrane of Xanthomonas oryzae pv. oryzae ruptured or deformed. The present results indicated novel derivatives of 5-phenyl sulfonate methyl 1,3,4-oxadiazole might be potential antibacterial agents.

The Research on the Effect of Br-Antibacterial Agents to Whitewater

2013 ◽  
Vol 726-731 ◽  
pp. 552-555
Author(s):  
Yong Hui Li ◽  
Mei Hong Niu ◽  
Na Li ◽  
Jian Zhang ◽  
Yan Ning Sun
Keyword(s):  
Antibacterial Agents ◽  
Antibacterial Effect ◽  
Culture Method ◽  
Inhibitory Effect ◽  
Actual Situation ◽  
Paper Pulp ◽  
Bacteriostatic Agent ◽  
Coated Plate ◽  
White Water ◽  
Better Than

This paper concerns with two brominated bacteriostatic agents, using the condition-test to research the inhibitory effect of the microorganisms in the waste paper pulp white water. Using the coated plate culture method of adding different amounts of antibacterial agents in Whitewater, the bacteria and mold in nutrient agar and potato medium experiments were used to observe the inhibitory effect. The results showed that the chosen brominated bacteriostatic agents (PS-2890, GB-3612) in this paper have a better antibacterial effect and 1#is better than 2#,the bacteriostatic agent can be chosen according to the actual situation of the plant .The bacteriostatic agent will achieve a higher rate of bacteriostasis when it is added to 5ppm, and this added amount can also meet the requirements of the factory on the prevention and treatment of microbial. The rate of bacteriostasis generally reached 40% -80% ,the highest 92.8%,when the antibacterial dosage is 3ppm-7ppm.

scholarly journals Antibacterial Activity of Methanolic Extracts from Lyngbya truncicola and Pseudanabaena sp.

2021 ◽  
Vol 10 (11) ◽  
pp. 192-199
Author(s):  
Olvera Ramírez Roxana Pineda López Margarita ◽  
Y Medina Jaritz Nora Beatriz
Keyword(s):  
Antibacterial Activity ◽  
Pathogenic Bacteria ◽  
Antibacterial Effect ◽  
Inhibitory Effect ◽  
New Drugs ◽  
Resistant Bacteria ◽  
Methanolic Extracts ◽  
Activity Test ◽  
Serovar Typhimurium ◽  
Reference Strains

One of the consequences of the abuse in the use of antibiotics is the emergence of resistant bacteria, wich causes new drugs to be sought, and thus makes it necessary to seek alternatives sources. There are many natural compounds, obtained from cyanobacteria, that have an inhibitory effect against various pathogenic bacteria. In this group of cyanobacteria are those belonging to the Lyngbya and Pseudanabaena genera; therefore, the aim of this work was to evaluate the antibacterial activity of methanolic extracts from L. truncicola and Pseudanabaena sp. against reference strains: Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli and Salmonella enterica ssp. enterica serovar Typhimurium. The cyanobacteria were propagated in BG-11 medium with constant aeration and a 12 hour light: dark photoperiod. The antibacterial activity test was carried out by the Kirby-Bauer method. The antibacterial effect was observed as growth inhibition halos. All the microorganisms presented suffered inhibition, the greater effect was produced on S. enterica ssp. enterica serovar Typhimurium. The largest halos were obtained with the extract of Lyngbya truncicola.

A comparative study of the antibacterial activity of Quercus robur (Ethanolic extract) and Zinc oxide nanoparticles on Salmonella (In vitro)

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Hams H. H. Alfattli ◽  
Ghufran Zuhair Jiber ◽  
Ghaidaa Gatea Abbass
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Zinc Oxide Nanoparticles ◽  
Quercus Robur ◽  
Ethanolic Extract ◽  
Inhibitory Effect ◽  
Significant Inhibition ◽  
Oxide Nanoparticles ◽  
Inhibition Zones

This study which designed to evaluate the inhibitory effect of Ethanolic extract of (Quercusrobur) and Zinc oxide nanoparticles on the growth of one genus of enterobacteriacae (Salmonella). In vitro. For this purpose graduate concentrates for plant extract (50, 100, 200, 400 )mg/ml which prepared and compared with Zinc oxide nanoparticles of different concentration (2, 1, 0.5, 0.25) μg/ml,and examined. The result showed that the studied medicinal plant has antibacterial activity against this bacteria which used. The result showed that the plant has good activity in decrease the growth of this bacteria. The results of the study also showed that the nano-ZnO has very effective antibacterial action against the studied bacteria which was Salmonella,nanoparticles concentrations lead to increasing in the inhibition zones of tested bacterial growth. We also study the effect of three antibiotics Lomefloxacin (LOM), Ciprofloxacin (SIP) and Rifampin (RA) and the result showed,in a comparison within the tested bacteria,Salmonella had a significant inhibition increase in Lomefloxacin ; the ciprofloxacin showed effect on tested bacteria. However,Rifampin does not show any effect on tested bacteria.

Antibacterial Activity of Biodegradable Particles based on Chitosan Containing Colloidal Silver

2020 ◽  
Vol 36 (4) ◽  
pp. 87-93
Author(s):  
V.Yu. Reshetova ◽  
A.F. Krivoshchepov ◽  
I.A. Butorova ◽  
N.B. Feldman ◽  
S.V. Lutsenko ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Polymer Matrix ◽  
Adipic Acid ◽  
Antibacterial Effect ◽  
Academic Excellence ◽  
Colloidal Silver ◽  
Scanning Electron Microscopy Data ◽  
Covalent Bonds ◽  
Agar Diffusion Test

Chitosan beads with colloidal silver nanoparticles inclued in the polymer matrix have been obtained by the introduction of chitosan into an acidified nanosilver sol. Dual interconnection of drops of the resulting solution was then carried out by ionotropic gelation at the first stage and covalent crosslinking of the polymer matrix with adipic acid at the second stage. The surface morphology of the obtained beads was studied by scanning electron microscopy. Data of Fourier transform IR spectroscopy confirmed the formation of covalent bonds between chitosan and adipic acid. The antibacterial activity of obtained beads against S. aureus and E. coli was evaluated using agar diffusion test. It was shown that the сhitosan beads modified with nanostructured silver exhibited an antibacterial effect against the tested strains, and they can be used as a basis for creating biodegradable wound healing dressings with a prolonged antibacterial effect. chitosan, silver nanoparticles, antibacterial activity, wound dressings This work was supported by the "Russian Academic Excellence Project 5-100". The study was carried out with the financial support of the Russian Foundation for Basic Research in the framework of the Scientific Project no. 18-29-18039.

Synthesis and Assessment of Novel Anti-chlamydial Benzylidene Acylhydrazides Derivatives

2018 ◽  
Vol 15 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Xiaofeng Bao ◽  
Ying Xue ◽  
Chao Xia ◽  
Yin Lu ◽  
Ningjing Yang ◽  
...  
Keyword(s):  
Inhibitory Effect ◽  
Dependent Manner ◽  
Iron Starvation ◽  
Hydrochloride Salt ◽  
Obligate Intracellular ◽  
Biphasic Life Cycle ◽  
Ic50 Value ◽  
Ic50 Values ◽  
Dose Dependent ◽  
Better Than

Background: Chlamydiae, characterized by a unique biphasic life cycle, are a group of Gram-negative obligate intracellular bacterial pathogens responsible for diseases in a range of hosts including humans. Benzylidene acylhydrazide CF0001 could inhibit chlamydiae independent of iron starvation and T3SS inhibition. This finding promoted us to design and synthesize more benzylidene acylhydrazides to find novel anti-chlamydial agents. Methods: The carboxylic acids 1a-1d were coupled with Boc-hydrazide inpresence of EDCI and DMAP to obtain the intermediate 2a-2d in 60-62% yields. N-Boc deprotections were performed to obtain hydrazide hydrochloride salt 3a-3d. Nextly, the hydrazides were subjected to condensation with aldehydes to obtain benzylidene acylhydrazides 4a-4g in 30-52% yields in two steps. Results: Compound 4d exhibited best inhibitory effect on the formation and growth of chlamydial inclusions. The IC50 value of compound 4d for infectious progenies was 3.55 µM, better than 7.30 µM of CF0001. Conclusion: To find novel anti-chlamydial agents, we have designed and synthesized benzylidene acylhydrazides 4a-4g. Compounds 4a, 4d, 4g showed inhibitory activity on C. muridarum with the IC50 values from 3.55-12 µM. The 3,5-dibromo-4-hydroxyl substitutes on ring B are critical to keep their anti-chlamydial activity. Compound 4d inhibited C. muridarum in a dose-dependent manner without apparent cytotoxicity.

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