Study on Antisepsis and Preservation of Dapingding Jujube

2014 ◽  
Vol 971-973 ◽  
pp. 174-177
Author(s):  
Zhan Ru Ma ◽  
Lan Chen ◽  
Xiao Bo Zhang ◽  
Xi Hong Li ◽  
Jin Shan Luo ◽  
...  
Keyword(s):  
Antibacterial Effect ◽  
Inhibitory Effect ◽  
Fruit Firmness ◽  
Microbial Infection ◽  
Postharvest Diseases ◽  
Cinnamon Oil ◽  
Rot Disease ◽  
Effect Of The Composition ◽  
Better Than

This paper investigated the microbial infection of postharvest diseases of Dapingding jujube and cited the symptoms of common rot disease .At the same time, the antibacterial effect of cinnamon oil, natamycin and their composition on Dapingding jujube during the period of storage were studied. The results showed that the preservation inhibitory effect of cinnamon oil was better than natamycin at earlier storage, but just the opposite at later storage, while, the effect of the composition had been very good during the whole storage with higher rate of intact fruit, better fruit firmness and lower cankered index.

Research on Properties of Antibacterial Paper Sprayed by Nano-Chitosan

2014 ◽  
Vol 926-930 ◽  
pp. 214-217
Author(s):  
Ying Hong ◽  
Li Ze Tang
Keyword(s):  
Staphylococcus Aureus ◽  
Tensile Strength ◽  
Antibacterial Effect ◽  
Circle Method ◽  
Inhibitory Effect ◽  
Bursting Strength ◽  
Obvious Change ◽  
And Staphylococcus Aureus ◽  
Better Than

Antibacterial paper for packaging was sprayed by nanochitosan as antibacterial ingredients. The bacteriostatic circle method was adopted to evaluate its antibacterial effect on E.coli and Staphylococcus aureus. We investigated the effects of different concentrations of nanochitosan on antibacterial paper thickness, tensile strength, bursting strength, folding strength and antibacterial properties.The results showed that: tensile strength, bursting strength and folding strength of the antibacterial paper is better than the control paper and the thickness has no obvious change. The antibacterial paper enhanced the antibacterial effect following the increasing concentration of nanochitosan. The same concentration of nanochitosan antibacterial paper, its inhibitory effect on E.coli was greater than that of Staphylococcus aureus.

scholarly journals The inhibitory effect of Eupatorium adenophorum extracts on the pathogen of postharvest disease of banana

2020 ◽  
Vol 185 ◽  
pp. 03038
Author(s):  
Weifeng Zhao ◽  
Weixiu Yang ◽  
Ying Li ◽  
Junying Cao ◽  
Xiaohuan Yang ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Antibacterial Effect ◽  
Inhibitory Effect ◽  
Postharvest Disease ◽  
Eupatorium Adenophorum ◽  
Post Harvest ◽  
Fusarium Semitectum ◽  
Colletotrichum Musae ◽  
Better Than ◽  
Three Components

The Colletotrichum musae and Fusarium semitectum Berk., Which often occur in banana after harvest were used as the targets. Three components with antibacterial activity extracted from the leaves of the plant were used as "fungicide". The antibacterial effect of the three component substances on the pathogens of anthracnose and shaft rot was studied. The results showed that the inhibitory rates of the components A, B and C at 2 mg / ml on the pathogens of banana anthracnose and shaft rot reached 82.53%, 79.91%, 78.30% and 82.2%, 78.69% and 81.17% respectively. The EC90 values of component A, B and C for banana anthracnose pathogens were 1.70, 1.85, and 1.69 mg / ml. Respectively, the EC90 values for banana shaft rot pathogens were 1.37, 1.38, and 1.64 mg / ml. The antibacterial effect of the three component substances on the pathogen of banana shaft rot was better than that of anthracnose. The three component substances have great potential for controlling post-harvest anthracnose and shaft rot of bananas.

The Research on the Effect of Br-Antibacterial Agents to Whitewater

2013 ◽  
Vol 726-731 ◽  
pp. 552-555
Author(s):  
Yong Hui Li ◽  
Mei Hong Niu ◽  
Na Li ◽  
Jian Zhang ◽  
Yan Ning Sun
Keyword(s):  
Antibacterial Agents ◽  
Antibacterial Effect ◽  
Culture Method ◽  
Inhibitory Effect ◽  
Actual Situation ◽  
Paper Pulp ◽  
Bacteriostatic Agent ◽  
Coated Plate ◽  
White Water ◽  
Better Than

This paper concerns with two brominated bacteriostatic agents, using the condition-test to research the inhibitory effect of the microorganisms in the waste paper pulp white water. Using the coated plate culture method of adding different amounts of antibacterial agents in Whitewater, the bacteria and mold in nutrient agar and potato medium experiments were used to observe the inhibitory effect. The results showed that the chosen brominated bacteriostatic agents (PS-2890, GB-3612) in this paper have a better antibacterial effect and 1#is better than 2#,the bacteriostatic agent can be chosen according to the actual situation of the plant .The bacteriostatic agent will achieve a higher rate of bacteriostasis when it is added to 5ppm, and this added amount can also meet the requirements of the factory on the prevention and treatment of microbial. The rate of bacteriostasis generally reached 40% -80% ,the highest 92.8%,when the antibacterial dosage is 3ppm-7ppm.

SKY59, A Novel Recycling Antibody for Complement-mediated Diseases

2020 ◽  
Vol 27 (25) ◽  
pp. 4157-4164 ◽  
Author(s):  
Taku Fukuzawa ◽  
Junichi Nezu
Keyword(s):  
Inhibitory Effect ◽  
Biologic Agent ◽  
Microbial Infection ◽  
Duration Of Action ◽  
Complement Activity ◽  
Body Of Knowledge ◽  
Therapeutic Benefits ◽  
Long Duration ◽  
Recycling Technology ◽  
Current Therapies

Background: The complement system usually helps protect against microbial infection, but it could also be involved in the onset of various diseases. Inhibition of complement component 5 (C5) with eculizumab has resulted in a significant reduction of hemolysis, reduction of thromboembolic events, and increased survival in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH). However, eculizumab requires frequent intravenous infusions due to the abundance of C5 in plasma and some patients may still experience breakthrough hemolysis. This review introduces the recent body of knowledge on recycling technology and discusses the likely therapeutic benefits of SKY59, a novel recycling antibody, for PNH and complement-mediated disorders. Methods: By using recycling technology, we created a novel anti-C5 antibody, SKY59, capable of binding to C5 pH-dependently. Results: In cynomolgus monkeys, SKY59 robustly inhibited C5 and complement activity for significantly longer than a conventional antibody. SKY59 also showed an inhibitory effect on C5 variant p.Arg885His, whereas eculizumab does not suppress complement activity in patients with this type of mutation. Conclusion: SKY59 is a promising anti-C5 biologic agent that has significant advantages over current therapies such as long duration of action and efficacy against C5 variants.

Synthesis and Assessment of Novel Anti-chlamydial Benzylidene Acylhydrazides Derivatives

2018 ◽  
Vol 15 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Xiaofeng Bao ◽  
Ying Xue ◽  
Chao Xia ◽  
Yin Lu ◽  
Ningjing Yang ◽  
...  
Keyword(s):  
Inhibitory Effect ◽  
Dependent Manner ◽  
Iron Starvation ◽  
Hydrochloride Salt ◽  
Obligate Intracellular ◽  
Biphasic Life Cycle ◽  
Ic50 Value ◽  
Ic50 Values ◽  
Dose Dependent ◽  
Better Than

Background: Chlamydiae, characterized by a unique biphasic life cycle, are a group of Gram-negative obligate intracellular bacterial pathogens responsible for diseases in a range of hosts including humans. Benzylidene acylhydrazide CF0001 could inhibit chlamydiae independent of iron starvation and T3SS inhibition. This finding promoted us to design and synthesize more benzylidene acylhydrazides to find novel anti-chlamydial agents. Methods: The carboxylic acids 1a-1d were coupled with Boc-hydrazide inpresence of EDCI and DMAP to obtain the intermediate 2a-2d in 60-62% yields. N-Boc deprotections were performed to obtain hydrazide hydrochloride salt 3a-3d. Nextly, the hydrazides were subjected to condensation with aldehydes to obtain benzylidene acylhydrazides 4a-4g in 30-52% yields in two steps. Results: Compound 4d exhibited best inhibitory effect on the formation and growth of chlamydial inclusions. The IC50 value of compound 4d for infectious progenies was 3.55 µM, better than 7.30 µM of CF0001. Conclusion: To find novel anti-chlamydial agents, we have designed and synthesized benzylidene acylhydrazides 4a-4g. Compounds 4a, 4d, 4g showed inhibitory activity on C. muridarum with the IC50 values from 3.55-12 µM. The 3,5-dibromo-4-hydroxyl substitutes on ring B are critical to keep their anti-chlamydial activity. Compound 4d inhibited C. muridarum in a dose-dependent manner without apparent cytotoxicity.

scholarly journals Antibacterial activity of plant extracts against Listeria monocytogenes isolated from ready-to-eat salads

2020 ◽  
Vol 13 (1) ◽  
pp. 131-143
Author(s):  
É. György ◽  
É. Laslo ◽  
E. Csató
Keyword(s):  
Listeria Monocytogenes ◽  
Essential Oils ◽  
Antibacterial Effect ◽  
Storage Conditions ◽  
Inhibitory Effect ◽  
Listeria Innocua ◽  
Foodborne Diseases ◽  
Bacterial Strains ◽  
Antibacterial Effects ◽  
Growth Environment

Abstract Ready-to-eat salads are becoming more and more popular. However, due to their ingredients, they represent a suitable growth environment for different microbes. In the prevention of foodborne diseases, hygienic food preparation and appropriate storage conditions are very important. During this study, ten different ready-to-eat salads were analysed for the presence of Listeria monocytogenes. Five different selective agar mediums were used for the enumeration and isolation of Listeria monocytogenes. The isolated bacterial strains were subjected to morphological and biochemical confirmation tests. The antibacterial effects of five different freshly squeezed vegetable juices (carrots, celery, beets, horseradish, and onions) and of five essential oils (dill, thyme, oregano, lemongrass, and sage) were determined against Listeria monocytogenes, Listeria innocua, and L. monocytogenes strains isolated from ready-to-eat salads. Based on the results obtained from fresh vegetable juices, carrot juice exerted the highest antibacterial effect, while the others showed no or slight inhibitory effect (horseradish, beets, onions) against Listeria species. Among the essential oils, thyme, lemongrass, and oregano showed the strongest antibacterial effect against the studied Listeria species.

scholarly journals Cinnamon oil downregulates virulence genes of poultry respiratory bacterial agents and revealed significant bacterial inhibition: An in vitro perspective

2019 ◽  
Vol 12 (11) ◽  
pp. 1707-1715 ◽  
Author(s):  
Ahmed Mohammed Erfan ◽  
Sherif Marouf
Keyword(s):  
Virulence Genes ◽  
Antibacterial Effect ◽  
Herbal Extract ◽  
Disk Diffusion ◽  
Economic Losses ◽  
Poultry Industry ◽  
Cinnamon Oil ◽  
Avibacterium Paragallinarum ◽  
Vitro Effect

Background and Aim: Respiratory bacterial agents represent one of the most harmful factors that ordinarily threaten the poultry industry and usually lead to great economic losses. Meanwhile, there is a global demand to avoid the highly emerging antibiotic resistance and antibiotic residues in edible meat. Whereas, the use of alternatives became of great priority, especially for those substances extracted from natural plant origin. The study aimed to evaluate the antibacterial effect of cinnamon oil as a herbal extract on different respiratory bacterial agents. Materials and Methods: One hundred and fifty biological samples were collected through targeted surveillance for respiratory diseased poultry farms representing three governorates, from which bacterial isolation and identification, DNA sequencing of representative strains were performed. Furtherly, phenotypic and genotypic evaluation of the antibacterial effect of cinnamon oil was performed by minimum inhibitory concentration, agar disk diffusion, and virulence genes expression real-time polymerase chain reaction. Results: Cinnamon oil gave rise to acceptable degrees of virulence genes downregulation of 0.15, 0.19, 0.37, 0.41, 0.77, and 0.85 for Staphylococcus aureus sed gene, Escherichia coli stx1 gene, Avibacterium paragallinarum HPG-2 gene, Pasteurella multocida ptfA gene, Mycoplasma gallisepticum Mgc2 gene, and Ornithobacterium rhinotracheale adk gene, respectively. Phenotypically, using agar disk diffusion assay and broth microdilution susceptibility, cinnamon oil showed also tolerable results as it stopped the growth of S. aureus, E. coli, P. multocida, and A. paragallinarum with varying zones of inhibition. Conclusion: The encountered results declared the successful in vitro effect of cinnamon oil that recommends its application for living birds for future use as a safe antibacterial in the poultry industry.

scholarly journals Comparison and Analysis of the Performances and Mechanisms of Recycled Asphalt Incorporating High-Permeability Rejuvenating Agent

2019 ◽  
Vol 2019 ◽  
pp. 1-16
Author(s):  
Yanjuan Tian ◽  
Mulian Zheng ◽  
Hailei Xu ◽  
Chupeng Chen ◽  
Jinhao Zhang
Keyword(s):  
Inhibitory Effect ◽  
The Self ◽  
Oxygen Absorption ◽  
Group Index ◽  
High Permeability ◽  
Recycled Asphalt ◽  
Modified Asphalt ◽  
The Matrix ◽  
Sbs Modified Asphalt ◽  
Better Than

The objective of this study is to develop a highly permeable rejuvenating agent for the recycling of the asphalt pavement. The rheological properties and permeability of recycled asphalt after adding the self-developed rejuvenating agent, as well as two other agents, were compared and evaluated. An improved softening point method was devised to evaluate the permeability. In addition, the recycled asphalt was analyzed using Fourier transform infrared spectroscopy (FTIR). The results showed that the self-developed rejuvenating agent had high permeability, could effectively restore the performance of the aged asphalt, and could improve the aging-resistant property of the recycled asphalt. FTIR analysis showed that the matrix asphalt experienced oxygen absorption and dehydrogenation during the aging process. The aging of the SBS-modified asphalt was achieved via dual aging of the matrix asphalt and SBS-modified components. In addition, the rejuvenating agent CA had an inhibitory effect on asphalt aging, and its recycling efficiency was better than that of the rejuvenating agent A for the aged SBS-modified asphalt. Finally, a relationship between the microscopic functional group index and the macroscopic test index was established.

Glycoprotein Biosynthesis: Stimulation of N-Acetylglucosaminyltransferase Activity by Cytidiee 5′-Diphosphocholine

1972 ◽  
Vol 50 (10) ◽  
pp. 1082-1093 ◽  
Author(s):  
Sailen Mookerjea
Keyword(s):  
Enzyme Activity ◽  
Phospholipase C ◽  
Inhibitory Action ◽  
Inhibitory Effect ◽  
Nucleotide Sugar ◽  
Inorganic Pyrophosphate ◽  
Golgi Membranes ◽  
Cationic Detergents ◽  
Better Than ◽  
Stimulation Of

The stimulatory effect of CDP-choline on N-acetylglucosaminyltransferase activity is marked in rough microsomes but is almost absent in Golgi-rich membranes or in serum. The marked CDP-choline effect on the enzyme is evident even when the nucleotide–sugar substrate concentration is raised to near saturation. Diglyceride has an inhibitory action on the enzyme which is effectively reversed by further addition of CDP-choline. Of the other different lipid factors tested only CDP-ethanolamine has a stimulatory effect similar to CDP-choline. CDP-choline alone activates the enzyme better than Triton. CDP-choline and Triton, in different combinations of doses, show a marked synergistic effect. Cationic detergents do not activate the enzyme and inorganic pyrophosphate almost completely inhibits the enzyme activity. Phospholipase A has an inhibitory effect in the presence of CDP-choline. Phospholipase C, by itself, stimulates the enzyme activity. In the presence of CDP-choline, a higher concentration of phospholipase C partially abolishes the CDP-choline effect on the enzyme. Phosphorylcholine from labeled CDP-choline is rapidly incorporated into lecithin in the assay system used for measuring N-acetylglucosaminyltransferase activity. Capacity for lecithin synthesis is poor in Golgi membranes. However, lecithin synthesis is stimulated by adding exogenous diglyceride, but CDP-choline plus diglyceride failed to activate N-acetylglucosaminyltransferase in Golgi membranes. Finally, various possibilities have been discussed to explain the mechanism of action of CDP-choline on the enzyme.

A Study on the Antibacterial Property of the Extract from Apocynum Venetum

2011 ◽  
Vol 332-334 ◽  
pp. 164-167
Author(s):  
Zheng Li ◽  
Zhen Feng Dong ◽  
Jian Fei Zhang ◽  
Ji Xian Gong ◽  
Fan Jie Meng
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Staphylococcus Aureus ◽  
Aspergillus Niger ◽  
Antibacterial Effect ◽  
Antibacterial Property ◽  
Absolute Ethanol ◽  
Antibacterial Substance ◽  
Apocynum Venetum ◽  
Better Than

In order to determined the antibacterial property of Apocynum venetum. Three kinds of extractants (distilled water, 75% ethanol and absolute ethanol) were used to extract the leaf, stick and skin of Apocynum venetum, respectively. Flask and plate methods were used to evaluate the antibacterial property of these extracts on four kinds of classical microbiologies, Escherichia coli, Staphylococcus aureus, Saccharomyces cerevisiae and Aspergillus niger, respectively. The results showed that the antibacterial rate of extract by 75 % ethanol was better than extracts by water or absolute ethanol on Escherichia coli and skin contained more antibacterial substance (on Escherichia coli) than others. The antibacterial rate of extract by distill water was better than extracts by 75 % ethanol or absolute ethanol on Staphylococcus aureus and stick contained more antibacterial substance (on Staphylococcus aureus) than others. Some of extracts had very weak antibacterial rate on Saccharomyces cerevisiae and all extracts had not antibacterial effect on Aspergillus niger.

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