scholarly journals Granular impacts: how far the Boussinesq model can go?

2021 ◽  
Vol 249 ◽  
pp. 03001
Author(s):  
Francisco Martinez ◽  
Claudia Gonzalez
Keyword(s):  
Pressure Distribution ◽  
Elastic Medium ◽  
Mechanical Response ◽  
Point Force ◽  
Surprising Result ◽  
Boussinesq Model ◽  
Isotropic Elastic Medium ◽  
The Impact ◽  
Static Point

A key problem on granular impacts deals with the determination of the mechanical response of the grains due to the impact of the intruder. This topic has been poorly addressed in the literature so far, a gap to which this study aims to contribute by measuring the pressure distribution at the bottom of a loose and dry sandy bed, impacted by a heavy sphere of fixed diameter. Exploring different bed thicknesses and intruder’s dropping height, we have found that the structure of this distribution is very similar to the Boussinesq model, initially proposed for a static point-force acting over an isotropic-elastic medium. This surprising result opens up many challenging questions that could help validate or refute this model in other scenarios.

scholarly journals Numerical modeling of lander interaction with a low-gravity asteroid regolith surface

2018 ◽  
Vol 615 ◽  
pp. A41 ◽  
Author(s):  
Florian Thuillet ◽  
Patrick Michel ◽  
Clara Maurel ◽  
Ronald-Louis Ballouz ◽  
Yun Zhang ◽  
...  
Keyword(s):  
Granular Media ◽  
Mechanical Response ◽  
Low Gravity ◽  
Frictional Material ◽  
Grazing Impacts ◽  
Impact Processes ◽  
Sample Return Mission ◽  
The Many ◽  
The Impact

Context. Landing on the surface of small bodies is particularly challenging, as the physical properties of the surface material are not well known and the mechanical response of this material in a low-gravity environment is not well understood. Aims. In order to improve our understanding of low-speed impact processes on granular media and their outcome in low-gravity environments, we consider the landing of the package MASCOT, to be released by the JAXA asteroid sample return mission Hayabusa2 on (162173) Ryugu in October 2018. Beyond addressing the theoretical aspects of the mechanical response of granular media in low gravity, this study also supports both engineering and scientific teams of Hayabusa2 in the search for the lander and in the determination of Ryugu’s surface properties. Methods. A campaign of hundreds of numerical simulations using the soft-sphere discrete element method implemented in the N-body code pkdgrav were performed to study the interaction between the lander and the low-gravity surface of the asteroid made of a granular medium representing the regolith. Assuming a broad range of regolith properties, and the lander’s trajectory and motion, we analyzed the outcomes of the landing (distance traveled by the lander, penetration depth, and shape of the traces left in the regolith surface) to determine the influence of the many parameters defining the properties of MASCOT and of the grains, and the ingoing motion of the lander. Results. We identify well-marked trends for the fate of the lander and the traces left in the granular material. Distances traveled by the lander are greater and penetrations are shallower for gravel-like media than for less frictional material. A similar trend is found for grazing impacts as opposed to vertical ones. Different regolith properties also generate different traces on the ground after the impact.

In situ determination of a rock mass modulus using a high resolution tiltmeter

1996 ◽  
Vol 33 (2) ◽  
pp. 350-355 ◽  
Author(s):  
Bassam Saleh ◽  
Abdallah I Husein Malkawi ◽  
Pierre A Blum
Keyword(s):  
Rock Mass ◽  
High Resolution ◽  
Boussinesq Model ◽  
New Approach ◽  
Structural Work ◽  
Rock Mass Modulus ◽  
Elastic Rock ◽  
The Impact

A very high resolution tiltmeter (10–8 rad, 0.002 s) developed by P.A. Blum, in 1957 was used to establish a new approach to directly evaluate the in situ average elastic rock-mass modulus. Five tiltmeters were installed on the facades of the Louvre museum to study the deformations induced by internal structural work and by the impact of the Paris metro traffic movement. The measured data from the tiltmeter were used to determine the elastic rock modulus of the museum's foundation using the Boussinesq model. The results obtained by the developed approach are consistent with the typical elastic rock-mass modulus for the rock found in the museum's foundations. Key words: rock-mass modulus, tiltmeter, deformation, Boussinesq model.

Assessment of sensitivity of the efficiency of regional tax spending towards investment attractiveness of the types of economic activity carried out by the residents of advanced development territory

2020 ◽  
pp. 98-110
Author(s):  
Evgeniya Mikhailovna Popova ◽  
Guzel Mukhtarovna Guseinova ◽  
Sergei Borisovich Milov
Keyword(s):  
Economic Activity ◽  
Socioeconomic Development ◽  
Federal District ◽  
Tax Incentives ◽  
Capital Investments ◽  
The Subject ◽  
Investment Process ◽  
The Impact ◽  
Advanced Development

The deficit of subnational budgets and deceleration capital investments in multiple Russian regions increase the relevance of research aimed at improvement of tax incentivizing practice of the regional investment process. The studies focused on determination of the impact of socioeconomic and institutional factors upon the efficiency of investment tax expenses obtained wide circulation within the foreign scientific literature. The subject of this article is the assessment of sensitivity of the efficiency of regional tax expanses towards investment attractiveness of the types of economic activity carried out by the residents of territories of advanced socioeconomic development, created in the subjects of Far Easter Federal District. The scientific novelty and practical values of this research consists in substantiation of the reasonableness of assessment of investment attractiveness of the types of economic activity that are stimulated by tax incentives. Methodology for assessing investment attractiveness is proposed and tested. The conclusion is made that in case of low investment attractiveness of the type of economic activity, which was planned to support by tax incentives, it is required to conduct and additional analysis to avoid unjustified tax expanses.

Method development for the determination of textural properties of sugar beet roots

2019 ◽  
pp. 392-400 ◽  
Author(s):  
Gunnar Kleuker ◽  
Christa M. Hoffmann
Keyword(s):  
Sugar Beet ◽  
Compression Test ◽  
Storage Period ◽  
Textural Properties ◽  
Small Sample ◽  
Root Tip ◽  
Flexural Test ◽  
Sample Distribution ◽  
The Impact

The harvest of sugar beet leads to root tip breakage and surface damage through mechanical impacts, which increase storage losses. For the determination of textural properties of sugar beet roots with a texture analyzer a reliable method description is missing. This study aimed to evaluate the impact of washing, soil tare, storage period from washing until measurement, sample distribution and number of roots on puncture and compression measurements. For this purpose, in 2017 comprehensive tests were conducted with sugar beet roots grown in a greenhouse. In a second step these tests were carried out with different Beta varieties from a field trial, and in addition, a flexural test was included. Results show that the storage period after washing and the sample distribution had an influence on the puncture and compression strength. It is suggested to wash the roots by hand before the measurement and to determine the strength no later than 48 h after washing. For reliable and comparable results a radial distribution of measurement points around the widest circumference of the root is recommended for the puncture test. The sample position of the compression test had an influence on the compressive strength and therefore, needs to be clearly defined. For the puncture and the compression test it was possible to achieve stable results with a small sample size, but with increasing heterogeneity of the plant stand a higher number of roots is required. The flexural test showed a high variability and is, therefore, not recommended for the analysis of sugar beet textural properties.

Development and Validation of an LC-MS/MS Method for Simultaneous Determination of Canagliflozin and Metformin HCl in Rat Plasma and its Application

2020 ◽  
Vol 16 (6) ◽  
pp. 752-762
Author(s):  
Vivek Nalawade ◽  
Vaibhav A. Dixit ◽  
Amisha Vora ◽  
Himashu Zade
Keyword(s):  
Internal Standard ◽  
Rat Plasma ◽  
Precipitation Method ◽  
Herbal Extracts ◽  
One Step ◽  
Precision And Accuracy ◽  
Development And Validation ◽  
The Impact ◽  
Metformin Hcl

Background: Food and herbal extracts rich in Quercetin (QRT) are often self-medicated by diabetics and can potentially alter the pharmacokinetics (PK) of Metformin HCl (MET) and Canagliflozin (CNG) leading to food or herb-drug interactions and reduced therapeutic efficacy. However, the impact of these flavonoids on the pharmacokinetic behaviour of MET and CNG is mostly unknown. Methods: A simple one-step protein precipitation method was developed for the determination of MET and CNG from rat plasma. The mobile phase chosen was MeOH 65% and 35% water containing 0.1% formic acid at a flow rate of 1mL/min. Results: The retention time of MET, internal standard (Valsartan) and CNG was 1.83, 6.2 and 8.2 min, respectively. The method was found to be linear in the range of 200 - 8000 ng/mL for CNG and 100 = 4000 ng/ml for MET. Precision and accuracy of the method were below 20% at LLOQ and below 15% for LQC, MQC, and HQC. Conclusion: The method was successfully applied for the determination of PK of MET and CNG by using 100 μL of rat plasma. QRT co-administration affects the PK parameters of MET and CNG. This alteration in PK parameters might be of significant use for clinicians and patients.

The Microeconomics of Product Innovation

2018 ◽  
Author(s):  
Paul Stoneman ◽  
Eleonora Bartoloni ◽  
Maurizio Baussola
Keyword(s):  
Product Innovation ◽  
New Products ◽  
Goods And Services ◽  
Product Innovations ◽  
Microeconomic Analysis ◽  
Prime Objective ◽  
Price Measurement ◽  
The Impact

The prime objective of this book is the use microeconomic analysis to guide and provide insight into the generation and adoption of new products. Taking an approach that uses minimal formal mathematics, the volume initially addresses questions of definitions, sources, and extent of product innovation, differentiating between goods and services; hard and soft innovations; horizontal and vertical innovations; original, new to market, and new to firm innovations. The sources of product innovations (e.g. R&D, design, and creativity) are explored empirically, and the extent of such innovations is then pursued using survey and other data. Three chapters are devoted to the theoretical analysis of the demand for and supply of new products and to the determination of firms’ decisions to undertake product innovation. Later chapters encompass empirical evidence on the determination of the extent of product innovation, the diffusion of such innovation, the impact of product innovation on firm performance, price measurement, and welfare, while the final chapter addresses policy issues.

Studies on Related ms Magnitude Rate Models in Triangular Wave Unloading Section of Calcium Medium-Fine Sandstone

2010 ◽  
Vol 152-153 ◽  
pp. 164-170
Author(s):  
Jie Liu ◽  
Jian Lin Li ◽  
Ying Xia Li ◽  
Shan Shan Yang ◽  
Ji Fang Zhou ◽  
...  
Keyword(s):  
Mechanical Response ◽  
Strain Curve ◽  
Experimental System ◽  
Constant Term ◽  
Lag Time ◽  
Vertical Force ◽  
Time Segment ◽  
Triangular Wave ◽  
Apparent Modulus ◽  
The Impact

Specific to the improvement in the present research of mechanical response under cyclic loading, this paper, taking the calcareous middle- coarse sandstone as the research subject and the RMT-150C experimental system in which data is recoded by ms magnitude as the platform, develops several related models concerning the unloading rate of triangle waves. The unloading process is divided into lag time segment and non-lag time segment, with criterions and related parameters provided as well. The term apparent elastic modulus is defined. The test data analysis shows that there exist a linear relationship between the apparent modulus and instant vertical force before load damage in non-lag time segment. On the preceding basis, a rate-dependent model of triangular wave un-installation section in non-lag time segment is established. Due to the inability of the loading equipment to accurately input the triangle wave, the average loading rate is amended and a constant term is added into it. The model is proved to be reliable, as the predicted value of the deformation rate and the stress strain curve coincides with measured value. At the same time, the impact of the lag time is pointed out quantitatively and a predication model of lag time segment is set up.

scholarly journals Viscoelastometry for detecting oral anticoagulants

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Philipp Groene ◽  
Daniela Wagner ◽  
Tobias Kammerer ◽  
Lars Kellert ◽  
Andreas Giebl ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Prospective Observational Study ◽  
Oral Anticoagulants ◽  
Plasma Concentrations ◽  
Factor Xa ◽  
Clotting Time ◽  
Emergency Situations ◽  
Tissue Plasminogen ◽  
The Impact

Abstract Background Determination of anticoagulant therapy is of pronounced interest in emergency situations. However, routine tests do not provide sufficient insight. This study was performed to investigate the impact of anticoagulants on the results of viscoelastometric assays using the ClotPro device. Methods This prospective, observational study was conducted in patients receiving dabigatran, factor Xa (FXa)-inhibitors, phenprocoumon, low molecular weight heparin (LMWH) or unfractionated heparin (UFH) (local ethics committee approval number: 17–525-4). Healthy volunteers served as controls. Viscoelastometric assays were performed, including the extrinsic test (EX-test), intrinsic test (IN-test) Russel’s viper venom test (RVV-test), ecarin test (ECA-test), and the tissue plasminogen activator test (TPA-test). Results 70 patients and 10 healthy volunteers were recruited. Clotting time in the EX-test (CTEX-test) was significantly prolonged versus controls by dabigatran, FXa inhibitors and phenprocoumon. CTIN-test was prolonged by dabigatran, FXa inhibitors and UFH. Dabigatran, FXa inhibitors and UFH significantly prolonged CTRVV-test in comparison with controls (median 200, 207 and 289 vs 63 s, respectively; all p < 0.0005). Only dabigatran elicited a significant increase in CTECA-test compared to controls (median 307 vs 73 s; p < 0.0001). CTECA-test correlated strongly with dabigatran plasma concentration (measured by anti-IIa activity; r = 0.9970; p < 0.0001) and provided 100% sensitivity and 100% specificity for detecting dabigatran. Plasma concentrations (anti-XA activity) of FXa inhibitors correlated with CTRVV-test (r = 0.7998; p < 0.0001), and CTRVV-test provided 83% sensitivity and 64% specificity for detecting FXa inhibitors. Conclusions In emergency situations, ClotPro viscoelastometric assessment of whole-blood samples may help towards determining the presence and type of anticoagulant class that a patient is taking. Trial registration German clinical trials database ID: DRKS00015302.

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