scholarly journals Zinc Status and Febrile Seizures: Results from a Cross-sectional Study

2020 ◽  
Vol 11 (04) ◽  
pp. 597-600
Author(s):  
Janani Arul ◽  
Peter Prasanth Kumar Kommu ◽  
Ananthanarayanan Kasinathan ◽  
Lopamudhra Ray ◽  
Lalitha Krishnan
Keyword(s):  
Odds Ratio ◽  
Serum Zinc ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Demographic Variables ◽  
Sectional Study ◽  
Cross Sectional ◽  
Zinc Levels ◽  
Level Of Significance

Abstract Objective To estimate the serum zinc levels in children under the age of 5 years with febrile seizures and febrile children without seizures Materials and Methods In this cross-sectional study from 2017 to 2018, 40 children with febrile seizures (simple and complex) were taken as cases. Forty age- and sex-matched febrile children without convulsions were recruited as controls. Serum zinc estimates were analyzed using a spectrophotometer (Biolis 50i–Autoanalyzer). Statistical Analysis The demographic variables and serum zinc estimates were analyzed using the Mann–Whitney test. The odds ratio was used to calculate the association of zinc deficiency in febrile seizures; 5% level of significance was considered. Results The mean serum concentrations of zinc in the cases and controls were 83.8 ± 33.1 μg/dL and 116.3 ± 30.3 μg/dL, respectively (p = 0.002). Hypozincemia defined by “a serum zinc level of less than 63 μg/dL” was found in 12 (30%) cases and 2(5%) controls with an odds ratio of 8:1. Conclusion Children with febrile seizures had significantly reduced concentrations of zinc in the serum.

scholarly journals Estimation of serum zinc levels in children with febrile convulsions

2018 ◽  
Vol 5 (4) ◽  
pp. 1518 ◽  
Author(s):  
Ubaidur Rehman H. ◽  
Shamshad Ahmed Khan ◽  
Prakash R. Saldanha
Keyword(s):  
Serum Zinc ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Sectional Study ◽  
Serum Zinc Level ◽  
Cross Sectional ◽  
Significant Difference ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background: Febrile seizures are the most common form of convulsion in children with the aged between 6 months to 6 years. Different studies have shown that reduction of zinc leads to the incidence of febrile seizures in children. This study was conducted with the goal of examination of the zinc level in the patients with Febrile Seizures.Methods: This cross sectional study was conducted on 50 children in two equal groups of children with febrile seizures, febrile children without seizures. In order to examine the zinc level blood samples were taken of all subjects and the zinc level of these patients was determined. The data was analyzed using the SPSS-16 statistical software and by descriptive statistical tests.Results: 31 males (47.2%) and 19 female children (52.8%) with the average age of 27.23±15.3 months were examined. The two groups had no significant difference in terms of age and sex. The average of zinc level in the patients with Febrile Seizures was 57.4 µg/dL and it was 116 µg/dL in the febrile children without FS there was a significant difference between the two groups in terms of the zinc level (P=0.01).Conclusions: The low serum zinc level in the group of patients with Febrile Seizures compared with children without febrile seizures indicate the existence of a relationship between the serum zinc level and development of FS in children aged between 6 months and 6 years.

scholarly journals The association between hypozincemia and aortic stenosis prevalence in hemodialysis patients: a single-center cross-sectional study

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Satoshi Matsui ◽  
Tomonaga Ameku ◽  
Daisuke Takada ◽  
Shinji Ono
Keyword(s):  
Aortic Stenosis ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Sectional Study ◽  
Single Center ◽  
Cross Sectional ◽  
Dialysis Vintage ◽  
Zinc Levels ◽  
Serum Zinc Levels

Abstract Background Hypozincemia contributes to phosphate-induced vascular calcification in model animals of renal failure, but the association between hypozincemia and aortic stenosis (AS) prevalence in patients with end-stage kidney disease remains unreported in clinical settings. Methods To investigate the association between hypozincemia and AS prevalence in patients undergoing hemodialysis, we designed a single-center cross-sectional study. Our outcome “AS” was defined as prevalence of moderate or severe AS or surgical history for AS. Depending on serum zinc levels, we divided patients undergoing hemodialysis into deciles. The association between hypozincemia and AS prevalence was analyzed via logistic regression adjusted for age, sex, dialysis vintage, diabetes history, serum albumin, and history of taking calcium-containing phosphate binder. Results Ninety-three patients undergoing hemodialysis were eligible. The mean serum zinc level was 61.3 ± 13.9 μg/dL. Twelve patients who belonged to 1st decile had serum zinc levels ≤ 48 μg/dL. Of these twelve patients, six patients (50 %) had AS. On the other hand, of eighty one patients who belonged to 2nd–10th deciles (serum zinc levels > 48 μg/dL), thirteen patients (16 %) had AS. Hypozincemia (serum zinc levels ≤ 48 μg/dL) was associated with AS prevalence (P = 0.038; odds ratio 4.43; 95% confidence interval 1.09–18.0). Conclusions AS was more prevalent in patients undergoing hemodialysis with severe hypozincemia in our cross-sectional study, although interventional studies are required to elucidate the benefit of zinc supplementation for AS progression.

scholarly journals Association between the number of prosthetic crowns and periodontitis: a cross-sectional study

2021 ◽  
Author(s):  
Yun-Jeong Kim ◽  
Jae-Young Lee ◽  
Young Ku ◽  
Hyun-Jae Cho
Keyword(s):  
Odds Ratio ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Nutrition Examination Survey ◽  
Regression Analyses ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Health Related

Abstract BackgroundAlthough the presence of prosthetic restorations has been associated with plaque accumulation, gingivitis, and periodontitis, there is a lack of large epidemiological investigations providing credible evidence on the association of prosthetic crowns with periodontitis. The purpose of the study was to analyze the association between the number of prosthetic crowns and the presence of periodontitis.MethodsThis study was based on the Seventh Korea National Health and Nutrition Examination Survey (2016-2018). A total of 12,689 participants over the age of 19 years were surveyed. Multivariate logistic regression analyses were used to identify the association between the number of prosthetic crowns and periodontitis after adjusting for potential confounders, including demographic variables, socio-economic characteristics, oral health-related variables, and oral and systemic clinical variables. ResultsThe odds ratio of periodontitis showed statistically significant differences in the anterior and posterior regions, and the prevalence of periodontal disease increased as the number of crown prostheses increased. Participants with 6–10 and 11 prosthetic crowns had 1.24 and 1.28 times higher prevalence of periodontitis, respectively, than patients with no prosthetic crown.ConclusionsThe results of this study show that the number of prosthetic crowns present in adults is related to the prevalence of periodontitis.

scholarly journals Association of Serum Zinc Level with Febrile Seizures in Children

2021 ◽  
pp. 200-203
Author(s):  
Maryum Naveed ◽  
Rimsha Mohsin ◽  
Palwasha Khan
Keyword(s):  
Febrile Seizure ◽  
Serum Zinc ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Control Group ◽  
Case Group ◽  
Serum Zinc Level ◽  
Cross Sectional

Introduction: Febrile seizure (FS), previously known as febrile convulsion, is the most common seizure in children. FS usually occurs between six months and five years of age. Aims and objectives: The main objective of the study is to find the association of serum zinc level with febrile seizures in children of Pakistan. Material and methods: This cross sectional study was conducted at Mayo Hospital, Lahore during June 2020 to January 2021. The data was collected from 164 patients of both genders. Results: The data was collected from 164 patients. In the case group, 46 children were male (53.3%), and 36 children (46.7%) were female. In the control group 44 children were male (43.3%) and 38 children were female (56.7%). The age of all participants was between one months and six years. Conclusion: It is concluded that low serum zinc levels are fairly un-sufficient to support the hypothesis that Zinc deficiency could not be a potential risk factor for febrile seizure in children.

scholarly journals Low Serum Zinc in Critically Ill Patients Fed Oral and Enteral Nutrition in a Brazilian Terciary Hospital: A Cross-Sectional Study

2021 ◽  
Vol 6 (6) ◽  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Medical Records ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Oral Nutrition ◽  
Flame Atomic Absorption ◽  
Zinc Levels

Purpose: Since zinc is required for immunity and inflammation regulations, this paper aimed to investigate serum zinc levels in critically ill patients receiving Enteral (EN) and Oral Nutrition (ON) and correlate these values with demographic, clinical and laboratory parameters. Material and Methods: This is a cross-sectional study. Researchers collected data from electronic medical records in Intensive Care Units (ICUs) of a Brazilian tertiary hospital. Flame Atomic Absorption Spectrophotometry measured serum zinc (normal range: 70-120 mcg/dl). Evaluated variables: age, sex, diagnoses, ICU type, iron, hemoglobin, leukocytes, C-reactive protein, severity score, and mortality. Results: Researches assessed 203 medical records. Mean zinc score was low (EN: 59.13 ±16.26 mcg/dl; ON: 64.75 ±16.80 mcg/dl; p= 0.010). Mean age was high (EN: 77.48 ± 16.26 years; ON: 75.01 ± 13.03 years; p= 0.012). Iron was positively correlated with zinc in EN (p= 0.012). Age was correlated negatively with zinc in ON (p=0.001). Hemoglobin was correlated positively with zinc in EN (p= 0.007) and ON (p= 0.018). Conclusions: Most of the ICU patients had low zinc. EN had lower zinc levels than ON. L

scholarly journals A study of zinc level in cord blood of neonates and its relationship with antropometric measurements in the neonates: a descriptive cross-sectional study

2019 ◽  
Vol 6 (2) ◽  
pp. 722
Author(s):  
Syed Mohamed ◽  
Santosh Kumar ◽  
J. Kumutha
Keyword(s):  
Cord Blood ◽  
Growth Parameters ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background: During pregnancy, fast growth and cell differentiation takes place in both mother and foetus. Maternal nutritional factors play an important role in the growth of the neonate. Among the micronutrient zinc is an important micronutrient whose deficiency is associated with poor pregnancy outcomes. The objective the current study was to evaluate the relationship of serum zinc concentration of the maternal blood and the neonatal cord blood with that of the infant’s anthropometric measurements.Methods: A descriptive cross-sectional study was performed under the Department of Neonatology, Saveetha medical college. Duration of the study was from April 2017 to June 2018. The study included 82 singleton mother baby dyads born in Saveetha medical college. Anthropometric measurements such as birth weight, head circumference, neonate length apart from other clinical features of both the mother and neonates were recorded for statistical analysis. Serum zinc levels were estimated using 2-(5-bromo-2-pyridylazo)-5-(N-Propyl-N-sulfopropylamino)-phenol (5-Br-PAPS) protocol.Results: The mean maternal age of the study population is 25.3±2.3 years. Majority of the mother had natural mode of delivery (57%). The mean cord serum zinc level was found to be 94.0±1.6microgram /dl and the mother’s serum zinc level was 93.8±30.7microgram /dl (range from 49 to 171microgram /dl) which was not found to be statistically significant. Serum zinc levels of the cord was compared with the child anthropometrics and mother’s serum zinc levels to assess for the significance, but there was no correlation observed between the umbilical cord, and the birth weight (r=0.03), length of the child (r=-0.02), head circumference (r=-0.07) and mothers serum zinc levels (r=-0.002).Conclusions: According to our results authors were unable to establish a relationship between Neonates growth parameters and zinc levels in neonates cord blood and zinc levels in the mother. Further studies with a larger sample size and prospective design would establish a causal relationship between zinc and growth parameters in the neonate.

scholarly journals Is Serum Zinc Level Associated with Prediabetes and Diabetes?: A Cross-Sectional Study from Bangladesh

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e61776 ◽  
Author(s):  
Md. Rafiqul Islam ◽  
Iqbal Arslan ◽  
John Attia ◽  
Mark McEvoy ◽  
Patrick McElduff ◽  
...  
Keyword(s):  
Serum Zinc ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Sectional Study ◽  
Serum Zinc Level ◽  
Cross Sectional

scholarly journals A Study of Serum Zinc level in Cirrhosis of Liver

2013 ◽  
Vol 5 (2) ◽  
pp. 44-47
Author(s):  
F Atia ◽  
N Sultana ◽  
S Ahmed ◽  
S Ferdousi ◽  
R Sultana ◽  
...  
Keyword(s):  
Serum Zinc ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Serum Zinc Level ◽  
Cross Sectional ◽  
Medical College ◽  
Cirrhotic Patients ◽  
Cirrhosis Of Liver ◽  
Zinc Levels ◽  
Age Range

Cirrhosis is a consequence of chronic liver diseases. Zinc is a micronutrient that plays an important role in the function of liver. This cross-sectional study was carried out in the Department of Biochemistry, Dhaka Medical College, from July 2010 to June 2011 to observe the association of serum zinc level with liver cirrhosis. A total of 100 adults, both males and females with age range of 18-60 years, of which 50 were healthy subjects and 50 adult hospitalised cirrhotic patients were selected purposively for the study according to selection crieteria. Fasting serum zinc level was measured with atomic absorption spectrophotometer. Serum zinc level was found to be low in 72% patients. Mean ±SD of serum zinc levels (?g/L) were 610.32 ± 169.60 and 827.66 ± 267.32 in cases and controls respectively. In cirrhotic patients serum zinc level was significantly lower than that of healthy controls (P<0.001). Though, it is difficult to draw any definite conclusion from this study, because of reduced level serum of zinc found in cirrhotics, Zn may be supplemented to them with a hope of better treatment response. DOI: http://dx.doi.org/10.3329/bjmb.v5i2.13340 Bangladesh J Med Biochem 2012; 5(2): 44-47

scholarly journals Influence of Breastfeeding and Complementary Feeding on Serum and Erythrocyte Zinc Levels in Preterm and Term Infants: A Cross-sectional Study

2021 ◽  
Author(s):  
Talita Rodrigues Azevedo e Silva ◽  
Anna Caroline Pereira Vivi ◽  
Fernando Luiz Affonso Fonseca ◽  
Cibele Wolf Lebrão ◽  
Maria Wany Louzada Strufaldi ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Preterm Infants ◽  
Complementary Feeding ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Term Infants ◽  
Cross Sectional ◽  
Zinc Levels ◽  
Serum Zinc Levels

Abstract Background: Zinc is an important micronutrient involved in cell division, growth, and immune system function. Most studies evaluating the nutritional status related to zinc and prematurity were conducted with hospitalized preterm infants. These studies show controversial results regarding the prevalence of deficiency, clinical implications, and the effect of zinc supplementation on mortality, infectious diseases, and growth in these groups. This study aimed to compare serum and erythrocyte zinc levels in a group of preterm and term infants during complementary feeding and related the zinc levels to dietary intake, and current nutritional condition in both groups. Methods: Cross-sectional study with 43 preterm infants (24 to 33 weeks) aged 9-24 months (mean: 14.3±6.4 months), compared with 47 term healthy infants. Data collected: socioeconomic status and maternal health during pregnancy, dietary history, anthropometry (weight, height, and head circumference), and current dietary intake. Laboratory tests: blood count, serum and erythrocyte zinc concentrations, and C-reactive protein.Results: Males predominated (24, or 55.8%) in the preterm group; the mean birth weight was 1,245±381.7 grams. Serum zinc levels <65 µg/dL and anemia were observed in four preterm (5.1%) and four term infants (5.3%), respectively. No infant had erythrocyte zinc < 40 µg/gHb. The variables independently associated with serum zinc levels were breastfeeding at the time of evaluation (20.11 µg/dL; 95% CI 9.62 to 30.60; p<0.001) and late (4-7 months) introduction of complementary feeding (6.6 µg/dL; 95% CI 5.3 to 11.4; p<0.001). Breastfeeding was also independently and directly associated with erythrocyte zinc levels (18.8 ug/dL; 95% CI 3.7 to 33.8; p=0.015). Conclusions: No difference was observed in the nutritional status related to zinc between preterm and term infants during complementary feeding. Serum and erythrocyte zinc levels were influenced by breastfeeding and the onset of solid foods.

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