scholarly journals Gel Phantom Models for Radiofrequency and Microwave Ablation of the Liver

2020 ◽  
Vol 04 (03) ◽  
pp. 303-310
Author(s):  
Willa J. Chen ◽  
Qi Wang ◽  
Charles Y. Kim
Keyword(s):  
Animal Models ◽  
Liver Cancer ◽  
Thermal Ablation ◽  
Microwave Ablation ◽  
Early Stage ◽  
Pros And Cons ◽  
Percutaneous Thermal Ablation ◽  
Future Potential ◽  
Gel Phantom

AbstractHeat-based percutaneous thermal ablation techniques have emerged as popular and effective treatments for liver cancer. As the technology continues to evolve, there is a need for optimized methods for experimentation to identify advantageous modifications and developments. Given that assessing and comparing resulting ablation zones in animal models are costly and resource-intensive, in vitro gel phantom models can serve an important role for early-stage experimentation. There exist several gel phantom recipes that have been reported in the literature. In this review, we will review the various recipes, the pros and cons to the existing models, and future potential directions.

Stereotactic Body Radiation and Other Ablative Therapies

2018 ◽  
Author(s):  
Praveen Sridhar ◽  
Hiran C Fernando
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Thermal Ablation ◽  
Stereotactic Body Radiation Therapy ◽  
Early Stage ◽  
Early Stage Lung Cancer ◽  
Curative Intent ◽  
Stereotactic Body Radiation ◽  
Percutaneous Thermal Ablation ◽  
Stage Lung Cancer

Lung cancer is the leading cause of cancer death in both men and women. This is related to the high prevalence and high mortality particularly when presenting at an advanced stage. Surgical resection remains the standard curative therapy for early-stage lung cancer. However, many patients are not able to tolerate resection secondary to poor respiratory reserve and other comorbid diseases. Stereotactic body radiation therapy (SBRT) and percutaneous thermal ablation are minimally invasive techniques that have been used to treat other solid tumors with curative intent. Over the past decade, there has been an expansion in the roles of both SBRT and thermal ablation in the treatment of early-stage lung tumors. The encouraging results from several studies have led to the incorporation of these therapies, particularly SBRT, as the standard of care for curative-intent treatment of patients with medically inoperable early-stage lung cancer. This chapter presents an overview of the approach to patient selection as well as provides a review of the current evidence for SBRT, percutaneous thermal ablation, and bronchoscopic ablation for early-stage nonsmall cell lung cancers. This review contains 3 figures, 4 tables, and 28 references Key Words: stereotactic body radiation therapy, percutaneous thermal ablation, cryoablation, microwave ablation, endoscopic ablation, bronchoscopic ablation, radiofrequency ablation, early stage NSCLC therapy

Pulmonary Ablation: A Primer

2014 ◽  
Vol 65 (2) ◽  
pp. 177-185 ◽  
Author(s):  
Benjamin J. Roberton ◽  
David Liu ◽  
Mark Power ◽  
John M.C. Wan ◽  
Sam Stuart ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Thermal Ablation ◽  
Microwave Ablation ◽  
Practical Knowledge ◽  
Early Stage ◽  
Treatment Options ◽  
Small Cell ◽  
Small Cell Lung ◽  
Image Guided

Percutaneous image-guided thermal ablation is safe and efficacious in achieving local control and improving outcome in the treatment of both early stage non–small-cell lung cancer and pulmonary metastatic disease, in which surgical treatment is precluded by comorbidity, poor cardiorespiratory reserve, or unfavorable disease distribution. Radiofrequency ablation is the most established technology, but new thermal ablation technologies such as microwave ablation and cryoablation may offer some advantages. The use of advanced techniques, such as induced pneumothorax and the popsicle stick technique, or combining thermal ablation with radiotherapy, widens the treatment options available to the multidisciplinary team. The intent of this article is to provide the reader with a practical knowledge base of pulmonary ablation by concentrating on indications, techniques, and follow-up.

scholarly journals Decision Making: Thermal Ablation Options for Small Renal Masses

2017 ◽  
Vol 34 (02) ◽  
pp. 167-175 ◽  
Author(s):  
Debra Gervais ◽  
Colin McCarthy
Keyword(s):  
Renal Cell Carcinoma ◽  
Thermal Ablation ◽  
Microwave Ablation ◽  
The United States ◽  
Treatment Modalities ◽  
Small Renal Masses ◽  
Renal Masses ◽  
Advantages And Disadvantages ◽  
Percutaneous Thermal Ablation ◽  
Total Nephrectomy

AbstractRenal cell carcinoma is a relatively common tumor, with an estimated 63,000 new cases being diagnosed in the United States in 2016. Surgery, be it with partial or total nephrectomy, is considered the mainstay of treatment for many patients. However, those patients with small renal masses, typically less than 3 to 4 cm in size who are deemed unsuitable for surgery, may be suitable for percutaneous thermal ablation. We review the various treatment modalities, including radiofrequency ablation, microwave ablation, and cryoablation; discuss the advantages and disadvantages of each method; and review the latest data concerning the performance of the various ablative modalities compared with each other, and compared with surgery.

scholarly journals Microwave ablation in the treatment of liver tumors. A better tool or simply more power?

2020 ◽  
Vol 22 (4) ◽  
pp. 451
Author(s):  
Zeno Sparchez ◽  
Tudor Mocan ◽  
Pompilia Radu ◽  
Iuliana Nenu ◽  
Mihai Comsa ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Liver Metastases ◽  
Intrahepatic Cholangiocarcinoma ◽  
Thermal Ablation ◽  
Microwave Ablation ◽  
Liver Tumors ◽  
Colorectal Cancer Liver Metastases ◽  
Clinical Scenarios

It has been a long time since tumor ablation was first tested in patients with liver cancer, especially hepatocellular carcinoma. Since than it has become a first line treatment modality for hepatocellular carcinoma. Over the years, the indications of thermal ablation have expanded to colorectal cancer liver metastases and intrahepatic cholangiocarcinoma as well. Together with the new indication for ablation, new ablation devices have been developed as well. Among them microwave ablation shows potential in replacing radiofrequency ablation as the preferred method of thermal ablation in liver cancer. The debate whether radiofrequency or microwave ablation should be the preferred method of treatment in patients with liver cancer remains open. The main purpose of this review is to offer some answers to the question: Microwave ablation in liver tumors: a better tool or simply more power? Various clinical scenarios will be analyzed including small, medium, and intermediate size hepatocellular carcinoma, colorectal cancer liver metastases and intrahepatic cholangiocarcinoma. Furthermore, the advantages, limitations, and technical considerations of MWA treatment will be provided also.

Percutaneous Thermal Ablation: Hydrodissection and Balloon Displacement to Protect Adjacent Non-Target Critical Structures

2018 ◽  
Author(s):  
Farrah J. Wolf ◽  
Jason Iannuccilli
Keyword(s):  
Thermal Ablation ◽  
Microwave Ablation ◽  
Thermal Injury ◽  
Contrast Material ◽  
Ablation Zone ◽  
Image Guided ◽  
Angioplasty Balloon ◽  
Ionic Contrast ◽  
Percutaneous Thermal Ablation ◽  
Physical Displacement

This chapter describes techniques that may be utilized to protect soft tissue structures and vessels that lie less than 1 cm from the planned ablation zone from thermal injury. Hydrodissection with dextrose 5% in water combined with non-ionic contrast material may be used as a means of providing mechanical displacement. Alternatively, an angioplasty balloon inflated with air may be used to provide both physical displacement and thermal insulation. This chapter provides an overview of the percutaneous image-guided thermal ablation technique as well as clinical examples, including microwave ablation of a renal cell carcinoma and radiofrequency ablation of a hepatocellular carcinoma, utilizing hydrodissection and balloon displacement techniques.

scholarly journals Role of percutaneous thermal ablation in cancer treatment

2021 ◽  
Author(s):  
Doha Jamal Ahmad ◽  
Amal Yahea Alyami ◽  
Abdullah Ahmed Alasker ◽  
Kholoud Bakur Fallatah ◽  
Reshan Mane AlReshan ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Thermal Ablation ◽  
Specific Volume ◽  
Microwave Ablation ◽  
The Other ◽  
Clinical Settings ◽  
Malignant Cells ◽  
Less Invasive ◽  
Percutaneous Thermal Ablation

The main aim of using thermal ablation strategies is to eliminate the targeted malignant cells within a specific volume. However, it should be noted that some researchers have reported the potential limitations of some of these techniques. On the other hand, more updated investigations indicated that these limitations could be overcome by the adjuvant use of other management modalities as chemotherapy. Many limitations have been reported with the modality, including the prolonged therapeutic time. Therefore, cryoablation and microwave ablation techniques were introduced in the literature as safe and efficacious modalities that overcame the limitations of the radiofrequency technique. Overall, percutaneous thermal ablation is associated with favorable outcomes and should be used in clinical settings due to the various advantages that have been reported for the modality, in addition to being less invasive.

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