scholarly journals Antioxidant activity of melon fruit (Cucumis melo L. ‘GMP’) ethanolic extract

2020 ◽  
Author(s):  
Muhammad Zulfikar ◽  
Faiza Senja Widya ◽  
Wiko Arif Wibowo ◽  
Budi Setiadi Daryono ◽  
Slamet Widiyanto
Keyword(s):  
Antioxidant Activity ◽  
Cucumis Melo ◽  
Ethanolic Extract ◽  
Cucumis Melo L ◽  
Melon Fruit

scholarly journals In vitro antioxidant activity and gastroprotective effect of ethanolic extract from Cucumis melo L. var. inodorus fruit on ethanol-induced gastric ulcer in rats

2020 ◽  
Vol 10 (5-s) ◽  
pp. 302-307
Author(s):  
Amel Bouaziz ◽  
Assia Bentahar ◽  
Saliha Djidel ◽  
Saliha Dahamna ◽  
Seddik Khennouf
Keyword(s):  
Antioxidant Activity ◽  
Gastric Ulcer ◽  
Hydroxyl Radical ◽  
Cucumis Melo ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Dry Extract ◽  
Cucumis Melo L ◽  
In Vitro Antioxidant Activity

The aim of this study was to estimate the content of polyphenols, flavonoids and tannins and to evaluate the antioxidant property and the antiulcer activity of the ethanolic extract of melon (Cucumis melo L. var. inodorus) pulp on ethanol-induced gastric ulcers in rats.  Ferric reducing power and hydroxyl radical scavenging tests were applied to evaluate the in vitro antioxidant activity. The polyphenolic and flavonoids contents of    melon extract were found to be 56.5 ± 2.49 mg GAE/g of dry extract and 0.43 ± 0.09 mg QE/ g of dry extract, respectively. Whereas the tannins content was 48. 30 ±  0. 9 mg ETA/ g of dry extract.  Melon pulp  extract exhibited  a good reducing potential   with  an  EC50 of  4.23 ± 0.08 mg/ml and high hydroxyl radical scavenging activity with IC50 of  1.83± 0.09 mg/ml. Oral administration of the melon pulp extract at doses of  200 and 600 mg/kg to rats  reduced gastric mucosal lesions  dose-dependently  with percentage protection of 56.56 and 93.79% compared to omeprazole (95.92 %) as reference drug. These results showed that the melon pulp extract had a good antioxidant activity and gastroprotective potential suggesting it use as an adjuvant in the treatment of gastric ulcer. Keywords: Cucumis melo var. inodorus, Polyphenols, Flavonoids, Tannins, Ulcer, Rat.

scholarly journals In-vitro antioxidant, anti-inflammatory and cytotoxic activity of Cucumis melo L. of ethanolic extract

Biomedicine ◽  
2021 ◽  
Vol 41 (2) ◽  
pp. 439-442
Author(s):  
G. Malathi ◽  
J. Vadivelu
Keyword(s):  
Antioxidant Activity ◽  
Cytotoxic Activity ◽  
Cucumis Melo ◽  
Protein Denaturation ◽  
Ethanolic Extract ◽  
Cytotoxic Activities ◽  
Dpph Method ◽  
Anti Inflammatory ◽  
Cucumis Melo L

Introduction and Aim: Cucumis melo L. commonly known as wild melon (in English) belongs to the family Cucurbitaceae and well distributed in rural areas. Cucumis melo L. is a annual climbing or perennial herb, distributed almost throughout India and neighbouring countries.  Nowadays food wastes are a major concern. On the other hand, the demand for natural valuable compounds to human health is increasing. These by-products contain phytochemical compounds with great nutritional and functional potentials. The fruits of this plant possess the abortifacient property and have antitussive, antioxidant, digestive, cytotoxic and anti-inflammatory properties.   Materials and Methods: The ethanolic extract was used to determine the antioxidant scavenging activity using DPPH method, protein denaturation for anti inflammatory studies, as well as in vitro cytotoxic activity by brine shrimp lethal assay (BSLA).   Results: The results obtained indicated highest antioxidant activity as compared to DPPH methods. The protein denaturation test showed the ethanolic extracts of Cucumis melo L. had effective anti-inflammatory activity. Extracts of Cucumis melo L. also registered potential cytotoxic activities by BSLA. This study provides the basis for further investigation of Cucumis melo L. for potential identification of novel bioactive compounds with therapeutic properties.   Conclusion: The presence of phytoconstituents such as flavonoids, terpenoids, alkaloids, may indeed assist to the antioxidant activity of fruit extract. That this next thing that must be done will be to conduct in vivo experiments and discern the histopathological mechanism.

scholarly journals STIMULASI HASIL MELON ( Cucumis melo, L) DENGAN MENGGUNAKAN BIOTO GROW GOLD (BGG)

2018 ◽  
Vol 15 (1) ◽  
pp. 35-41
Author(s):  
SAHINDAH ARITONANG ◽  
SURTINAH SURTINAH
Keyword(s):  
Data Analysis ◽  
Cucumis Melo ◽  
Sugar Content ◽  
Fruit Weight ◽  
Leaf Length ◽  
Stem Diameter ◽  
Leaf Width ◽  
Randomized Design ◽  
Cucumis Melo L ◽  
Melon Fruit

The experiment was conducted experimentally using non-factorial Randomized Design (RAL) with 5 (five) treatment levels without Bioto Grow Gold, Bioto Grow Gold 1 ml liter-1 water, Bioto Grow Gold 2 ml liter -1 water, giving Bioto Grow Gold 3 ml liter-1 water and giving Bioto Grow Gold 4 ml liter-1 water. The data analysis used variance and continued with a different test of Duncan treatment average at p 0.05. The results showed that BGG treatment had the significant effect on leaf length, leaf width, stem diameter, flowering age, fruit circumference, fruit weight, a thickness of flesh and sugar content of melon fruit. The best treatment is giving Bioto Grow Gold 3 ml liter-1 water.

scholarly journals New Chromone and Triglyceride from Cucumis melo Seeds

2014 ◽  
Vol 9 (2) ◽  
pp. 1934578X1400900
Author(s):  
Sabrin R. M. Ibrahim
Keyword(s):  
Antioxidant Activity ◽  
Cytotoxic Activity ◽  
Cucumis Melo ◽  
Spectral Measurements ◽  
Dpph Assay ◽  
Meoh Extract ◽  
Mass Spectral ◽  
Cucumis Melo L ◽  
First Time

Re-investigation of the MeOH extract of the seeds of Cucumis melo L. var. reticulatus (Cucurbitaceae) led to the isolation of a new chromone derivative (5,7-dihydroxy-2-[2-(3-methoxy-4-hydroxyphenyl)ethyl]chromone (5) and a triglyceride (1,3-di-(6 Z,9 Z)-docosa-6,9-dienoyl-2-(6 Z) hexacos-6-enoylglycerol (1), together with three known compounds; α-spinasterol (2), stigmasta-7,22,25-trien-3-ol (3), and D:B-friedoolean-5-ene-3-β-ol (4), are reported from this species for the first time. Their structures were determined by extensive 1D (1H, 13C, and DEPT) and 2D (1H-1H COSY, HMQC, and HMBC) NMR and mass spectral measurements. Compound 5 displayed significant cytotoxic activity against L5178Y cells, with an ED50 of 5 μM. The MeOH extract and 5 showed antioxidant activity using the DPPH assay.

Valorization of melon fruit (Cucumis melo L.) by-products: Phytochemical and Biofunctional properties with Emphasis on Recent Trends and Advances

2020 ◽  
Vol 99 ◽  
pp. 507-519 ◽  
Author(s):  
Ricardo Gómez-García ◽  
Débora A. Campos ◽  
Cristóbal N. Aguilar ◽  
Ana R. Madureira ◽  
Manuela Pintado
Keyword(s):  
Cucumis Melo ◽  
Recent Trends ◽  
Cucumis Melo L ◽  
By Products ◽  
Melon Fruit

scholarly journals KARAKTERISTIK PERMEN JELLY TIMUN SURI (Cucumis melo L.) DENGAN PENAMBAHAN SORBITOL DAN EKSTRAK KUNYIT (Curcuma domestika Val.)

2010 ◽  
Vol 5 (2) ◽  
pp. 78 ◽  
Author(s):  
Merynda Indriyani Syafutri ◽  
Eka Lidiasari ◽  
Hendra Indawan
Keyword(s):  
Antioxidant Activity ◽  
Water Content ◽  
Cucumis Melo ◽  
Total Sugar ◽  
Font Size ◽  
Chemical Laboratory ◽  
Randomized Design ◽  
S Factor ◽  
Agricultural Faculty ◽  
Cucumis Melo L

<p class="MsoNormal" style="margin: 0cm 7.1pt 6pt 14.2pt; text-align: justify;"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">The objective of this <span class="longtext">research was to determine the chemical and organoleptic </span>characteristics</span><span class="longtext"><span style="font-size: 10pt;"> of Cucumis melo L. jelly candies </span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">with the addition of </span></span><span class="longtext"><span style="font-size: 10pt;">sorbitol and Curcuma domestika Val. extract</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">. <span style="background: #FFFFFF none repeat scroll 0% 0%;">This research was conducted in the Chemical Laboratory of Agricultural, Department of Agricultural Technology, Agricultural Faculty, Sriwijaya University</span></span></span><span class="longtext"><span style="font-size: 10pt;">,</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us"> Indralaya, from January 2010 to June 2010.</span></span><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">This research used a Factorial Completely Randomized Design with two treatments and three replications for each treatment<span class="longtext">. S factor was the addition of sorbitol concentration (9%, 16% and 23%) and E was the concentration factor addition of </span></span><span class="longtext"><span style="font-size: 10pt;">Curcuma domestika Val. extract</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us"> (5%, 7% and 9%). The results showed that the addition of sorbitol concentration had significant effect on the water content, pH, total sugar and antioxidant activity of </span></span><span class="longtext"><span style="font-size: 10pt;">Cucumis melo L. jelly candies</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">. The addition of </span></span><span class="longtext"><span style="font-size: 10pt;">Curcuma domestika Val. extract</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us"> had significant effect on the water content and antioxidant activity of </span></span><span class="longtext"><span style="font-size: 10pt;">Cucumis melo L. jelly candies</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">. Interaction addition of sorbitol and </span></span><span class="longtext"><span style="font-size: 10pt;">Curcuma domestika Val. extract</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us"> had significant effect on the antioxidant activity of jelly candies.</span></span><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">S<sub>2</sub>E<sub>2 </sub><span class="longtext">treatment (sorbitol 20% and 7.5% </span></span><span class="longtext"><span style="font-size: 10pt;">Curcuma domestika Val. extract</span></span><span class="longtext"><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">) was the best treatment with <span style="background: #FFFFFF none repeat scroll 0% 0%;">chemical </span></span></span><span style="font-size: 10pt;" lang="en-us" xml:lang="en-us">characteristics<span class="longtext"><span style="background: #FFFFFF none repeat scroll 0% 0%;"> (water content 36.48%, ash content 3.01%, pH 5.03,</span> total sugar 37.00% and the antioxidant activity 27.09%), and sensory </span>characteristics<span class="longtext"> by scoring preferences (color 3.08, texture 2.88, odour 3.08  and taste 2.88).</span></span></p>

scholarly journals An Evaluation of the Antioxidant Activity of a Methanolic Extract of Cucumis melo L. Fruit (F1 Hybrid)

Separations ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 123
Author(s):  
R. S. Rajasree ◽  
Sibi P. Ittiyavirah ◽  
Punnoth Poonkuzhi Naseef ◽  
Mohamed Saheer Kuruniyan ◽  
G. S. Anisree ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Antioxidant Activity ◽  
Cucumis Melo ◽  
Methanolic Extract ◽  
Antioxidant Activities ◽  
Reducing Power ◽  
Total Antioxidant Activity ◽  
F1 Hybrid ◽  
Total Antioxidant ◽  
Cucumis Melo L

Cucumis melo L. (C. melo) is a fruit with many medicinal properties and is consumed in various countries. It is utilised for chronic eczema and to treat minor burns and scrapes. The present study was conducted to evaluate the antioxidant activity of a methanolic extract of Cucumis melo Linn (MECM). A coarse powder prepared from the fruit and seeds was extracted with methanol (absolute) by a hot continuous percolation process in accordance with the standard protocols. All the extracts were estimated for potential antioxidant activities with tests such as an estimation of total antioxidant activity, hydroxyl radical and nitric oxide scavenging activity and reducing power ability. The qualitative analysis of the methanolic extract of C. melo fruit showed the presence of various phytochemical constituents such as carbohydrates, alkaloids, sterols, phenolic compounds, terpenes and flavonoids. The total antioxidant activity of concentrations of 50, 100 and 200 µg were tested and observed to be 3.3 ± 0.1732, 6.867 ± 0.5457 and 13.63 ± 0.8295 µg of ascorbic acid, respectively. The results also showed significant nitric oxide and DPPH scavenging activities as well as a reducing power activity of MECM. Thus, our results suggest that MECM may serve as a putative source of natural antioxidants for therapeutic and nutraceutical applications.

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