The effect of dietary lipid changes on the fatty acid composition and function of liver, heart and brain mitochondria in the rat at different ages

A correlation between dietary lipids and cellular enzyme activities is a problem that has only been partially addressed by nutritionists. Therefore, changes in the fatty acid composition and the activities of some key metabolic enzymes (ubiquinol-2-cytochrome c reductase (EC 1.10.2.2), cytochrome oxidase (EC 1.9.3.1) and ATPase (EC 3.6.1.3)) in the mitochondria of liver, heart and brain of rats fed on diets differing extensively in their polyunsaturated fatty acid compositions have been investigated. The results showed that fatty acid compositional changes brought about by the dietary differences were associated with extensive changes in the activities of these key enzymes in the mitochondria. The extent of the influence differed considerably with the period over which the diets were fed. The role of dietary lipids to effect changes through the preservation of membrane structural integrity is discussed.

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Interrelationships of Dietary Lipids Upon Fatty Acid Composition of Brain Mitochondria, Erythrocytes and Heart Tissue in Chicks

American Journal of Clinical Nutrition ◽

10.1093/ajcn/13.6.362 ◽

1963 ◽

Vol 13 (6) ◽

pp. 362-368 ◽

Cited By ~ 27

Author(s):

B. CENTURY ◽

L. A. WITTING ◽

C. C. HARVEY ◽

M. K. HORWITT

Keyword(s):

Fatty Acid Composition ◽

Fatty Acid ◽

Acid Composition ◽

Brain Mitochondria ◽

Heart Tissue ◽

Dietary Lipids

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Role of dietary lipids on fetal tissue fatty acid composition and fetal survival in swine at 42 days of gestation

Journal of Animal Science ◽

10.2527/1995.7351372x ◽

1995 ◽

Vol 73 (5) ◽

pp. 1372-1380 ◽

Cited By ~ 18

Author(s):

A. Perez Rigau ◽

M. D. Lindemann ◽

E. T. Kornegay ◽

A. F. Harper ◽

B. A. Watkins

Keyword(s):

Fatty Acid Composition ◽

Fatty Acid ◽

Acid Composition ◽

Fetal Tissue ◽

Dietary Lipids ◽

Tissue Fatty Acid Composition ◽

Fetal Survival ◽

Tissue Fatty Acid

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Alterations in fatty acid composition and volatile compounds in muscle of large yellow croaker Larimichthys crocea fed different dietary lipid sources

Aquaculture Reports ◽

10.1016/j.aqrep.2021.100688 ◽

2021 ◽

Vol 20 ◽

pp. 100688

Author(s):

Hua Mu ◽

Jun Li ◽

Xiaoyi Pan ◽

Jiahuan Liu ◽

Jia Chen ◽

...

Keyword(s):

Fatty Acid Composition ◽

Fatty Acid ◽

Volatile Compounds ◽

Acid Composition ◽

Dietary Lipid ◽

Large Yellow Croaker ◽

Larimichthys Crocea

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Temperature and Aging Affect Glyphosate Toxicity and Fatty Acid Composition in Allonychiurus kimi (Lee) (Collembola)

Toxics ◽

10.3390/toxics9060126 ◽

2021 ◽

Vol 9 (6) ◽

pp. 126

Author(s):

June Wee ◽

Yun-Sik Lee ◽

Yongeun Kim ◽

Jino Son ◽

Kijong Cho

Keyword(s):

Fatty Acid Composition ◽

Fatty Acid ◽

Aging Time ◽

Acid Composition ◽

Chronic Effect ◽

Residual Concentration ◽

Significant Toxicity ◽

Collembolan Species ◽

Glyphosate Degradation ◽

Fatty Acid Compositions

Glyphosate is the most used herbicide worldwide, but enormous use of glyphosate has raised concerned about its environmental loadings. Although glyphosate is considered non-toxic, toxicity data for soil non-target organisms according to temperature and aging are scarce. This study examined the toxicity of glyphosate with the temperature (20 °C and 25 °C) and aging times (0 day and 7 days) in soil using a collembolan species, Allonychiurus kimi (Lee). The degradation of glyphosate was investigated. Fatty acid composition of A. kimi was also investigated. The half-life of glyphosate was 2.38 days at 20 °C and 1.69 days at 25 °C. At 20 °C with 0 day of aging, the EC50 was estimated to be 93.5 mg kg−1. However, as the temperature and aging time increased, the glyphosate degradation increased, so no significant toxicity was observed on juvenile production. The proportions of the arachidonic acid and stearic acid decreased and increased with the glyphosate treatment, respectively, even at 37.1 mg kg−1, at which no significant effects on juvenile production were observed. Our results showed that the changes in the glyphosate toxicity with temperature and aging time were mostly dependent on the soil residual concentration. Furthermore, the changes in the fatty acid compositions suggest that glyphosate could have a chronic effect on soil organisms.

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