Effects of dietary vitamin E and C supplementation on heart failure in fast growing commercial broiler chickens

2008 ◽  
Vol 49 (6) ◽  
pp. 697-704 ◽  
Author(s):  
S. Nain ◽  
C. Wojnarowicz ◽  
B. Laarveld ◽  
A.A. Olkowski
2005 ◽  
Vol 2005 ◽  
pp. 167-167
Author(s):  
H. A. Yousefzadeh ◽  
I. Yousefian ◽  
B. Navidshad ◽  
M. Safari

While vitamins naturally occurring in plant and animal based feed ingredients can supply a reasonable proportion of the birds daily needs, their contribution is rarely considered during formulation. This situation arises due to variability, especially in cereals and vegetable proteins, for example, the vitamin E content of corn can vary from 10 to 40 IU/kg. Because of this uncertainty in the natural supply of vitamins within a feed, the bird’s vitamin supply is therefore met by the addition of synthetic vitamins, usually in the form of a so called premix, that contains all vitamins and perhaps some other micronutrients and feed additives. This premixes use according to producer suggestions and in some cases their doses can be higher than real requirements. Skinner et al (1992) removed vitamin premixes from 21 day of age and did not report any adverse effects. Gwyther et al (1992) showed sever performance reduction by vitamin premix withdrawal from 21 to 49 day of age. This experiment was conducted to determine the effects of Vitamin supplement levels on broiler chickens from 28 to 49 days of age.


2011 ◽  
Vol 24 (10) ◽  
pp. 1440-1446 ◽  
Author(s):  
Jian-xiong Xu ◽  
Xiao-lian Chen ◽  
Jing Wang ◽  
Tian Wang

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011373
Author(s):  
Essi Hantikainen ◽  
Ylva Trolle Lagerros ◽  
Weimin Ye ◽  
Mauro Serafini ◽  
Hans-Olov Adami ◽  
...  

ObjectiveTo determine whether high baseline dietary antioxidants and total non-enzymatic antioxidant capacity (NEAC) is associated with a lower risk of Parkinson disease in men and women, we prospectively studied 43,865 men and women from a large Swedish cohort.MethodsIn the Swedish National March Cohort 43,865 men and women aged 18–94 years were followed through record linkages to National Health Registries from 1997 until 2016. Baseline dietary vitamin E, C and beta-carotene intake, as well as NEAC, were assessed by a validated food frequency questionnaire collected at baseline. All exposure variables were adjusted for energy intake and categorized into tertiles. Multivariable Cox proportional hazard regression models were fitted to estimate hazard ratios (HRs) with 95% confidence intervals (CIs) for Parkinson disease.ResultsAfter a mean follow-up time of 17.6 years we detected 465 incidence cases of Parkinson disease. In the multivariable adjusted model, dietary vitamin E (HR: 0.68: 95% CI: 0.52–0.90; p for trend: 0.005) and C (HR: 0.68; 95% CI: 0.52–0.89; p for trend: 0.004) were inversely associated with the risk of Parkinson disease, when comparing subjects in the highest to the lowest tertiles of the exposure. No association was found with estimated intake of dietary beta-carotene or NEAC.ConclusionOur findings suggest that dietary vitamin E and C intake might be inversely associated with the risk of Parkinson disease. No association was found with dietary beta-carotene or NEAC.Classification of evidenceThis study provides Class III evidence that dietary vitamin E and C intake are inversely associated with the risk of Parkinson disease.


2019 ◽  
Vol 51 (12) ◽  
pp. 1698-1705 ◽  
Author(s):  
Dana Ivancovsky-Wajcman ◽  
Naomi Fliss-Isakov ◽  
Federico Salomone ◽  
Muriel Webb ◽  
Oren Shibolet ◽  
...  

2012 ◽  
Vol 302 (1) ◽  
pp. R49-R58 ◽  
Author(s):  
Deon B. Williams ◽  
Zhongxiao Wan ◽  
Bruce C. Frier ◽  
Rhonda C. Bell ◽  
Catherine J. Field ◽  
...  

Glucocorticoid excess induces marked insulin resistance and glucose intolerance. A recent study has shown that antioxidants prevent dexamethasone (DEX)-induced insulin resistance in cultured adipocytes. The purpose of this investigation was to examine the effects of dietary vitamin E and C (Vit E/C) supplementation on DEX-induced glucose intolerance in rats. We hypothesized that feeding rats a diet supplemented with Vit E/C would improve glucose tolerance and restore insulin signaling in skeletal muscle, adipose, and liver and prevent alterations in AMPK signaling in these tissues. Male Wistar rats received either a control or Vit E/C-supplemented diet (0.5 g/kg diet each of l-ascorbate and dl-all rac-alpha-tocopherol) for 9 days prior to, and during, 5 days of daily DEX treatment (subcutaneous injections 0.8 mg/g body wt). DEX treatment resulted in increases in the glucose and insulin area under the curve (AUC) during an intraperitoneal glucose tolerance test. The glucose, but not insulin, AUC was lowered with Vit E/C supplementation. Improvements in glucose tolerance occurred independent of a restoration of PKB phosphorylation in tissues of rats stimulated with an intraperitoneal injection of insulin but were associated with increases in AMPK signaling in muscle and reductions in AMPK signaling and the expression of fatty acid oxidation enzymes in liver. There were no differences in mitochondrial enzymes in triceps muscles between groups. This study is the first to report that dietary Vit E/C supplementation can partially prevent DEX-induced glucose intolerance in rats.


2010 ◽  
Vol 27 (2) ◽  
pp. 103-110 ◽  
Author(s):  
Navid Hosseini-Mansoub ◽  
Saeid Chekani-Azar ◽  
Ali Tehrani ◽  
Alireza Lotfi ◽  
Mostaan Manesh

Influence of dietary vitamin E and zinc on performance, oxidative stability and some blood measures of broiler chickens reared under heat stress (35 °C)This study was conducted to determine the effects of vitamin E (αTA; dL-α-Tocopheryl acetate) and zinc (Zn; ZnCl2) on performance, oxidative stability and some blood measures of broiler chickens under normal and hot temperatures. One hundred sixty 10-day-old male chicks were assigned to four groups in four replicates. The birds received two diets, control and enriched with two levels of vitamin E and Zn (100 and 50 mg/kg of diet, respectively) under two ambient temperatures (22 °C and 35 °C). Although the diets enriched with the antioxidant vitamin and element compared with un-enriched diets resulted in the better performance of the birds, significant differences were related to temperature conditions, as the lowest feed conversion ratio (FCR) and the highest body weight (BW) were observed in the group fed the enriched diet under normal temperature. The serum malondialdehyde (MDA), cholesterol (C), triglycerides (TG), glucose (G), total protein (TP), and hematocrit and heterophil: lymphocyte ratio levels were significantly lower in birds reared under 22 °C compared with the group under 35 °C but the hematocrit was not significantly lower in groups fed enriched diets and exposed to normal conditions (P>0.05). It was concluded that a combination of 100 mg of vitamin E and 50 mg of Zn provides the better performance and the least blood C and TG levels accompanying the better oxidative stability in male broilers under normal temperature (22 °C) and that this combination can be considered as a protective strategy in broiler diets for reducing the negative effects of heat stress.


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