This chapter focuses on the work-related hazards faced by pornography performers and other laborers in the adult entertainment industry workforce. The chapter reviews demographics and characteristics of pornography performers, what health-related and other challenges those in the industry face because of their work, which organized groups support their collective health and safety on the job, and what policies have been drafted that seek to address pornography performers’ health and safety. The chapter details health hazards, including sexually transmitted infections (STIs), violence on set, stigma, the challenges of working as independent contractors, and lack of wage transparency in the industry. The chapter emphasizes that occupational safety and health hazards faced by performers are undoubtedly compounded when performers are Black, Latinx, transgender, or identify as belonging to another marginalized group. Public health advocates should focus on promoting the well-being of those who work in the pornography industry by establishing meaningful, long-term, trusting partnerships with those presently working in the industry.