The Psychedelic Renaissance in Clinical Research: A Bibliometric Analysis of Three Decades of Human Studies with Classical Psychedelics

Abstract Background The aim of this bibliometric analysis was to evaluate the clinical trials of randomized controlled trials (RCTs) of colorectal cancer all the world over the past decade. Methods The PubMed and Web of Science database were searched to obtain a randomized controlled trial of colorectal cancer from January 1, 2008 to January 1, 2018.The included literatures were analyzed with the bibliometric analysis. Results In the past 10 years, Randomized controlled trials of colorectal cancer have shown an upward trend; Most of the top ten research institutions in the literature are from the USA, the UK and other regions which has the high incidence of colorectal cancer; Most of the related research journals are also sponsored by European and American countries; the frequently cited top 15 literatures are mostly international multi-center clinical research, and there are fewer participants in Chinese research institutions. By keyword co-occurrence, colorectal cancer research mostly involves screening, disease-free survival, drug treatment, surgical methods, clinical trials, quality of life and prognosis; The results of the co-authorship network analysis show that Chinese researchers are less involved in international cooperation. Conclusions High-quality randomized controlled trials are increasingly favored by top international journals. However, there is still a large gap in clinical research between China and abroad. Researchers should gradually implement the standardization and accuracy of clinical trials, strengthen international multi-center cooperation and emphasize quality control.

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Trends and Development in Clinical Research of FDA-Approved Drugs Against Interleukin-1β: A Bibliometric Analysis.

10.21203/rs.3.rs-1091297/v1 ◽

2021 ◽

Author(s):

Qi Tan ◽

ZiMo Yang ◽

Wenjuan Chen ◽

Yang Jin

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Research ◽

Bibliometric Analysis ◽

Clinical Studies ◽

Inflammatory Diseases ◽

Hot Spot ◽

Descriptive Analysis ◽

The United States ◽

Approved Drugs ◽

Fda Approved Drugs

Abstract Background Interleukin(IL)-1β is a promising target for many diseases such as atherosclerosis, rheumatoid arthritis and cancer because it has been found to involve in the development of diseases. Anakinra, Canakinumab and Rilonacept were three Food and Drug Administration (FDA)-approved drugs and used for inhibiting IL-1β. Our study aims to access the trends and development for IL-1β inhibitors using bibliometric analysis. Methods All publication records were obtained from databases Web of Science and Pubmed. Publishing characteristics including organization, author, journals and co-authorship, Keywords, co-occurrence network, related journals network were analyzed by VOSviewer 1.6.16 (by Leiden University) and Bibliometric package in R(4.0.5). Graph prism 8 was used to performed descriptive analysis of all data. Results 274 publications were enrolled in our study. Of the three drugs, anakinra has been extensively studied, with 130 publications related to it between 1997 and 2021. Clinical studies on IL-1β antagonists mainly focused on rheumatoid arthritis. Non-inflammatory diseases such as cardiovascular disease and cancer were also found in the related clinical research. The United States published the most articles in clinical research on IL-1β inhibitor and it was the country that participated in the most collaborations. Conclusion Targeting IL-1β was still a hot spot for clinical research in inflammatory diseases. As progresses are made in the field, Canakinumab and Rilonocept as two novel inhibitors, will increase in a similar trend to that of Anakinra. The number of studies about the inhibitors targeting IL-1β in inflammatory diseases will emerge more in the future. Cancer therapy might be the trend in the clinical studies of antagonizing IL-1β.

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Probiotics in the Treatment of Colorectal Cancer

Medicines ◽

10.3390/medicines5030101 ◽

2018 ◽

Vol 5 (3) ◽

pp. 101 ◽

Cited By ~ 21

Author(s):

Robert Hendler ◽

Yue Zhang

Keyword(s):

Colorectal Cancer ◽

Cancer Therapy ◽

Cancer Risk ◽

Literature Review ◽

Drug Metabolism ◽

Clinical Research ◽

Human Microbiome ◽

Human Studies ◽

Colorectal Cancer Risk ◽

Response To Treatment

The human microbiome plays many roles in inflammation, drug metabolism, and even the development of cancer that we are only beginning to understand. Colorectal cancer has been a focus for study in this field as its pathogenesis and its response to treatment have both been linked to the functioning of microbiota. This literature review evaluates the animal and human studies that have explored this relationship. By manipulating the microbiome with interventions such as probiotic administration, we may be able to reduce colorectal cancer risk and improve the safety and effectiveness of cancer therapy even though additional clinical research is still necessary.

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A Bibliometric Analysis of Global Clinical Research by Anesthesia Departments

Anesthesia & Analgesia ◽

10.1213/01.ane.0000286149.57763.e7 ◽

2007 ◽

Vol 105 (6) ◽

pp. 1741-1746 ◽

Cited By ~ 24

Author(s):

Madhav Swaminathan ◽

Barbara G. Phillips-Bute ◽

Katherine P. Grichnik

Keyword(s):

Clinical Research ◽

Bibliometric Analysis

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A Bibliometric Analysis of Global Clinical Research by Anesthesia Departments

Survey of Anesthesiology ◽

10.1097/01.sa.0000307943.80222.5b ◽

2008 ◽

Vol 52 (4) ◽

pp. 202-203

Author(s):

&NA;

Keyword(s):

Clinical Research ◽

Bibliometric Analysis

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Mapping Trends and Hotspots Regarding Clinical Research on COVID-19: A Bibliometric Analysis of Global Research

Frontiers in Public Health ◽

10.3389/fpubh.2021.713487 ◽

2021 ◽

Vol 9 ◽

Author(s):

Demeng Xia ◽

Renqi Yao ◽

Sheng Wang ◽

Gaoqi Chen ◽

Yin Wang

Keyword(s):

Clinical Trials ◽

Clinical Research ◽

Bibliometric Analysis ◽

Web Of Science ◽

H Index ◽

Medical Virology ◽

The World ◽

Number Of Citations ◽

Emerging Topics ◽

The Web

Purpose: The coronavirus disease 2019 (COVID-19) outbreak, which began in December 2019, has not been completely controlled; therefore, COVID-19 has received much attention from countries around the world. Many related clinical studies, such as clinical trials, have been published, but to the knowledge of the authors, there has been no bibliometric analysis of these publications focusing on clinical research studies on COVID-19.Methods: Global publications on COVID-19 from January 2020 to December 2020 were extracted from the Web of Science (WOS) collection database. The VOSviewer software and CiteSpace were employed to perform a bibliometric study. In addition, we obtained information on relevant clinical trials from the website http://clinicaltrials.gov.Results: China published most of the articles in this field and had the highest number of citations and H-index. The Journal of Medical Virology published most of the articles related to COVID-19. In terms of institutions, Huazhong University of Science and Technology had the most publications, and Wang, JW received the highest number of citations.Conclusion: The diagnosis, prevention, and prognosis of COVID-19 are still the focus of attention at present. The overall analysis of the disease were identified as the emerging topics from the perspectives of epidemiology and statistics. However, finding an effective treatment remains the focus of clinical trials.

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The Contribution of the Brazilian Dental Journal to the Brazilian Scientific Research over 30 Years

Brazilian Dental Journal ◽

10.1590/0103-6440202004551 ◽

2020 ◽

Vol 31 (1) ◽

pp. 3-9

Author(s):

Carlos Estrela ◽

Jesus Djalma Pécora ◽

Manoel Damião Sousa-Neto

Keyword(s):

Clinical Research ◽

Bibliometric Analysis ◽

Dental Materials ◽

Basic Research ◽

Research Area ◽

Google Scholar ◽

Universal Language ◽

Thirtieth Anniversary ◽

Scopus Database ◽

Brazilian Studies

Abstract The Brazilian Dental Journal (BDJ) was officially launched in 1990, stimulated by the courage and boldness of researchers dedicated to teaching and research in dentistry. The journal was conceived in a worldwide coverage and universal language to allow publication of the results of Brazilian studies, which otherwise would not be accessible to the scientific dental community. In the year we celebrate the thirtieth anniversary of BDJ, this article presents a brief overview of Brazilian dental research and a bibliometric analysis of the articles published in this journal as a contribution to our readers and fellow researchers. The purpose was to identify the mot frequent categories of study, the most published areas of dentistry and BDJ’s top 50 most-cited articles in the Scopus and Google Scholar databases. A search was performed on all BDJ online issues published from 1990 to 2019. In this period, BDJ published 1,710 articles. Based on their distribution by category of study, 557 articles were in the basic research/dental materials area, 527 in the basic research/biology area and 280 in the clinical research area. Eight articles were cited more than 100 times in the Scopus database and 266 times in the Google Scholar database. Endodontics was the most published area. This overview of BDJ production over those 30 years allows establishing a profile of the characteristics, impact and trends of the published studies, as well as the journal’s contribution to the top 50 most-cited articles in the Scopus and Google Scholar databases.

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